Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Foram encontrados 4967 produtos de "Esteroides e Derivados"
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Estrone 3-Acetate
CAS:Produto ControladoFórmula:C20H24O3Cor e Forma:White To Off-WhitePeso molecular:312.40Testosterone Enol Diacetate
CAS:Produto Controlado<p>Applications Controlled substance.<br></p>Fórmula:C23H32O4Cor e Forma:NeatPeso molecular:372.5Mifepristone
CAS:Produto Controlado<p>Applications Mifepristone is a progesterone receptor antagonist with partial agonist activity. Abortifacient.<br>References Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)<br></p>Fórmula:C29H35NO2Cor e Forma:White To Light YellowPeso molecular:429.59Z,Z-Dienestrol
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications A metabolite of Diethylstilbestrol.<br>References Liehr, J.G., et al.: Steroids, 40, 713 (1982),<br></p>Fórmula:C18H18O2Cor e Forma:NeatPeso molecular:266.334-Hydroxy Ospemifene (Ospemifene Impurity)
CAS:<p>Applications 4-Hydroxy Ospemifene is an Ospemifene (O703000) impurity, used to treat dyspareunia. It is a selective estrogen receptor modulator (SERM) acting similarly to an estrogen.<br>References Rutanen, E., et al.: Menopause, 10, 433 (2003);<br></p>Fórmula:C24H23ClO3Cor e Forma:NeatPeso molecular:394.89Chlormadinone
CAS:Produto Controlado<p>Applications It has been used in combinations as an oral contraceptive.<br>References Brennan, D.M., et al.: Acta Endocrinol., 44, 367 (1963), Honma., s., et al.: Chem Pharm. Bull., 25 2019 (1977), Usui, T., et al.: Acta Urol. Jpn., 27, 327 (1981),<br></p>Fórmula:C21H27ClO3Cor e Forma:NeatPeso molecular:362.89Estrone 3-Sulfate Sodium Salt, Stabilized with TRIS
CAS:Fórmula:C18H21O5S·NaCor e Forma:NeatPeso molecular:372.41Digitoxin-21,23,23-d3
CAS:Produto Controlado<p>Applications Isotope labelled Digitoxin (D445950), is used as a cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Foerster, et al.: Arch. Int. Pharmacodyn. Ther., 159, 1 (1966), Jakovljevic, I.M., Anal. Profiles Drug Subs., 3, 149 (1974)<br></p>Fórmula:C41H61D3O13Pureza:90%Cor e Forma:NeatPeso molecular:767.962-Methyl-N-[3-(trifluoromethyl)phenyl]propanamide
CAS:Produto ControladoFórmula:C11H12F3NOCor e Forma:NeatPeso molecular:231.21Pregna-4,14-diene-3,20-dione
CAS:Produto Controlado<p>Impurity Progesterone EP Impurity A<br>Applications Pregna-4,14-diene-3,20-dione (Progesterone EP Impurity A) is a Progesterone derivative<br>References Wilks, J., et al.: Steroids, 35, 697 (1980), Templeton, J., et al.: J. Med. Chem., 30, 1502 (1987), Blackmore, P., et al.: Mol. Pharmacol., 49, 727 (1996),<br></p>Fórmula:C21H28O2Cor e Forma:NeatPeso molecular:312.45Desmosterol-d6
CAS:Produto Controlado<p>Applications A labelled metabolite of Cholesterol (C432501).<br>References Marx, J., et al.: Science, 294, 508 (2001), Plosch, T., et al.: J. Biol. Chem., 277, 33870 (2002), Lund, E., et al.: J .Biol. Chem., 278, 22980 (2003),<br></p>Fórmula:C272H6H38OCor e Forma:NeatPeso molecular:390.67Estrone Enol Diacetate
CAS:Produto Controlado<p>Applications Estrone Enol Diacetate can be applied as a substrate for human paroxonases. A steroid with potential to be inhibitor of NADH-oxidase and succinate oxidase.<br>References Teiber, J. et al.: Arch. Biochem. Bioiphys. 461, 24 (2007); Stoppani, A. et al.: Arch. Biochem. Biophys., 127, 463 (1968)<br></p>Fórmula:C22H26O4Cor e Forma:Off-WhitePeso molecular:354.44Testosterone Undecanoate-d3
CAS:Produto Controlado<p>Applications A Labelled metabolite of Testosterone (T155000). It is a promising androgen for male hormonal contraception.CONTROLLED SUBSTANCE<br>References Glass, A., et al.: J. Clin. Endocrinol. Metab., 45, 1211 (1977), Behre, H., et al.: Eur. J. Endocrinol., 140, 414 (1999), Nieschlag, E., et al.: Steroids, 68, 965 (2003), Wang, C., et al.: J. Clin. Endocrinol. Metab., 91, 460 (2006),<br></p>Fórmula:C30H45D3O3Cor e Forma:NeatPeso molecular:459.729,11-Didehydrooestriol
CAS:Produto Controlado<p>Impurity Estriol EP Impurity A<br>Stability Hygroscopic<br>Applications 9,11-Didehydrooestriol (Estriol EP Impurity A) is an impurity of Estriol (E888960), a metabolite of Estradiol (E888000). An estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929), Huffman, et al.: J. Biol. Chem., 169, 167 (1947),<br></p>Fórmula:C18H22O3Cor e Forma:Off-WhitePeso molecular:286.37(2α)-Methyl Megestrol Acetate
CAS:Produto Controlado<p>Impurity Megestrol Acetate EP Impurity H<br>Applications (2α)-Methyl Megestrol Acetate (Megestrol Acetate EP Impurity H) is a related impurity in Megestrol acetate (M208050).<br>References Schneider, F., et al.: Helv. Chim. Acta, 56, 2396 (1973), Aisner, J., et al.: Semin. Oncol., 15, 68 (1988), Krischenowski, D., et al.: Steroids, 58, 278 (1993), Bratoeff, E., et al.: Chem. Pharm. Bull., 51, 1132 (2003),<br></p>Fórmula:C25H34O4Cor e Forma:NeatPeso molecular:398.5416-Epiestriol
CAS:Produto Controlado<p>Impurity Estriol EP Impurity F<br>Applications 16-Epiestriol (Estriol EP Impurity F) is a metabolite of Estradiol.<br>References Marrian, B., et al.: Biochem. J., 59, 136 (1955), Dietel, M., et al.: Cancer Res., 50, 6100 (1990), Schumacher, G., et al.: Clin. Cancer Res., 5, 493 (1999), Robert, J., et al.: J. Med. Chem., 46, 4805 (2003),<br></p>Fórmula:C18H24O3Cor e Forma:WhitePeso molecular:288.38Dexamethasone Sodium Sulfobenzoate
CAS:Produto Controlado<p>Applications Dexamethasone Sodium Sulfobenzoate is related to Dexamethasone (D298800) a steroid that regulates T cell survival, growth, and differentiation.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995); Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999); Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999);<br></p>Fórmula:C29H32FO9S·NaCor e Forma:NeatPeso molecular:598.615-Oxo Atorvastatin
CAS:<p>Applications Atorvastatin Derivative<br></p>Fórmula:C33H33FN2O5Cor e Forma:NeatPeso molecular:556.6219-Hydroxy Cholesterol
CAS:<p>Applications A metabolite of Cholesterol. Cholesterol oxidation product having cytotoxicity effects.<br>References Higley, N., et al.: Food Chem. Toxicol., 22, 983 (1984), Emanuel, H., et al.: J. Food Sci., 56, 843 (1991), Kilsdonk, E., et al.: J. Lipid Res., 36, 505 (1995), Cantwell, H., et al.: Cell Biol. Toxicol., 14, 401 (1998),<br></p>Fórmula:C27H46O2Cor e Forma:NeatPeso molecular:402.656(7)-Dehydro Norgestrel
CAS:<p>Impurity Levonorgestrel EP Impurity M<br>Applications 6(7)-Dehydro Norgestrel (Levonorgestrel EP Impurity M) is a Norgestrel (N689500) impurity.<br>References Gorog, S., et al.: J. Chromatogr., 400 177 (1987),<br></p>Fórmula:C21H26O2Cor e Forma:NeatPeso molecular:310.43(Z)-Guggulsterone
CAS:Produto Controlado<p>Applications (Z)-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.<br>References Yang, D. et al.: J. Lipid Res., 53, 529 (2012); El-Mekkawy, S. et al.: Nat. Prod. Res., 27, 146 (2013);<br></p>Fórmula:C21H28O2Cor e Forma:NeatPeso molecular:312.45(16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione
CAS:Produto Controlado<p>Impurity Betamethasone EP Impurity C<br>Applications (16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione (Betamethasone EP Impurity C) is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient.<br>References Reeves, E.K.M., et al.: Bioorg., Med. Chem., 21, 2241 (2013), Xiong, Y., et al.: J. Pharm. Biomed. Anal., 49, 646 (2009)<br></p>Fórmula:C22H28O4Cor e Forma:NeatPeso molecular:356.4617α-Progesterone
CAS:<p>Applications 17α-Progesterone is a testosterone precursror generated from cholesterol. Also used as a diagnostic agent in the identification and study of ovarian Leydig cell tumor disease.<br>References Vesely, D. et al.: Proc. Natl. Acad. Sci. USA., 76, 3491 (1979); Arhan, E. et al.: J. Pediatric Endocrinol. Metab., 21, 181 (2008);<br></p>Fórmula:C21H30O2Cor e Forma:NeatPeso molecular:314.46δ7-Avenasterol (E/Z mixture)
CAS:<p>Applications Δ7-Avenasterol is an analog of Stigmasterol (S686750); a plant sterol that is used as a precursor in the synthesis of progesterone.<br>References Han, P., et al.: Biotechnol. App. Biochem., 54, 105 (2009); Matsunaga, I., et al.: Anal. Biochem., 393, 222 (2009); Huang, C., et al.: Plant Physiol., 150, 1192 (2009)<br></p>Fórmula:C29H48OCor e Forma:White To Off-WhitePeso molecular:412.6924(R/S)-Hydroxycholesterol-d7
CAS:Produto Controlado<p>Applications 24(R/S)-Hydroxycholesterol-d7 is used in the study of biochemical methods for quantitative detection of steroids containing quantitative charge tags and oxidizing agents and using mass spectroscopy for detection.<br>References Groffoths, Williams., US 20150233953, (2015)<br></p>Fórmula:C272H7H39O2Cor e Forma:NeatPeso molecular:409.70Betamethasone 21-Valerate
CAS:<p>Impurity Betamethasone Valerate EP Impurity E<br>Applications Betamethasone 21-Valerate (Betamethasone Valerate EP Impurity E) is an isomeric impurity of Betamethasone 17-Valerate (B327075), as an corticosteroid. Betamethasone 21-Valerate was generated in the stress study of the active drug Betamethasone 17-Valerate (B327075).<br>References Caron, J.C., et al.: J. Pharmaceut. Sci., 73, 1703 (1984); Stouch, T.R., et al.: J. Med. Chem., 29, 2125 (1986);<br></p>Fórmula:C27H37FO6Cor e Forma:WhitePeso molecular:476.58Desonide-21-aldehyde Hydrate
Produto ControladoFórmula:C24H32O7Cor e Forma:White To Light YellowPeso molecular:432.507Digitoxin
CAS:<p>Stability Hygroscopic<br>Applications Cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Foerster, et al.: Arch. Int. Pharmacodyn. Ther., 159, 1 (1966), Jakovljevic, I.M., Anal. Profiles Drug Subs., 3, 149 (1974)<br></p>Fórmula:C41H64O13Cor e Forma:White To Off-WhitePeso molecular:764.94Eplerenone Hydroxyacid Potassium Salt
CAS:Produto Controlado<p>Applications A metabolite of Eplerenone. Used in combination therapy for treatment of cardiovascular disorders.<br>References Staessen, J., et al.: J. Endocrinol., 91, 457 (1981), de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), MacFadyen, R., et al.: Cardiovasc. Res., 35, 30 (1997),<br></p>Fórmula:C24H31O7·KCor e Forma:Off-White To Light YellowPeso molecular:470.60Testosterone 17-Decanoate
CAS:Produto Controlado<p>Applications Testosterone 17-Decanoate, is an ester of Testosterone (T155000). Testosterone 17-Decanoate, can be used as a potential long-acting male contraceptive, with the combination of subcutaneous etonogestrel implants .<br>References Brady, B. M., et al.: Human Reproduction, 21 (1), 285 (2006); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000);<br></p>Fórmula:C29H46O3Cor e Forma:NeatPeso molecular:442.6717-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid
Produto Controlado<p>Applications 17-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid is an intermediate used to prepare (11β,17α)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-androsta-1,4-diene-17-carboxylic acid (E890570) which is a derivative of Loteprednol Etabonate (L471400), an ophthalmic corticosteroid.<br>References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)<br></p>Fórmula:C20H24O5Cor e Forma:NeatPeso molecular:344.4017-Hydroxy Pregnenolone
CAS:Produto Controlado<p>Applications 17-Hydroxy Pregnenolone, is a metabolite of Pregnenolone (P712200).<br>References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),<br></p>Fórmula:C21H32O3Cor e Forma:White To Off-WhitePeso molecular:332.48(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:<p>Applications (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, can be used for the synthesis of Calicoferol E, a vitamin D3 analogues.<br>References Vir Singh, T., et al.: ARKAT USA, INc., (2002);<br></p>Fórmula:C22H28O5Cor e Forma:White To Light RedPeso molecular:372.4520(α)-Dihydro Pregnenolone
CAS:<p>Applications 20α-Dihydro Pregnenolone is a metabolite of Pregnenolone (P712200).<br>References Purdy, R., et al.: J. Med. Chem., 33, 1572 (1990), Bixo, M., et al.: Brain Res., 764, 173 (1997), Huang, X., et al.: J. Biol. Chem., 275, 29452 (2000),<br></p>Fórmula:C21H34O2Cor e Forma:NeatPeso molecular:318.4917β-Estradiol
CAS:Produto Controlado<p>Impurity Ethinylestradiol EP Impurity D<br>Applications 17b-Estradiol is the major estrogen (1) secreted by the premenopausal ovary (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.<br></p>Fórmula:C18H24O2Cor e Forma:NeatPeso molecular:272.3813-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-5(10)-en-20-yn-3-one(Levo Norgestrel Impurity)
CAS:Produto Controlado<p>Impurity Levonorgestrel EP Impurity B<br>Applications 13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-5(10)-en-20-yn-3-one (Levonorgestrel EP Impurity B) is an impurity of Levonorgestrel.<br>References McGinty, D., et al.: Endocrinology, 24, 829 (1939), Belanger, A., et al.: Steroids, 37, 361 (1981), Nieman, L., et al.: J. Clin. Endocrinol. Metab., 61, 536 (1985), Klebe, G., et al.: J. Med. Chem., 37, 4130 (1994),<br></p>Fórmula:C21H28O2Cor e Forma:NeatPeso molecular:312.45Testosterone 17-Isobutyrate
CAS:Produto Controlado<p>Applications Testosterone ester.<br>References Zarzycki, P., et al.: Anal. Bioanal. Chem., 391, 2219 (2008), Talarovicova, A., et al.: Hormon. Behav., 55, 235 (2009),<br></p>Fórmula:C23H34O3Cor e Forma:Off-WhitePeso molecular:358.51Flurandrenolide
CAS:Produto Controlado<p>Applications Glucocorticoid; antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Fórmula:C24H33FO6Cor e Forma:NeatPeso molecular:436.51Exemestane-19-d3
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications An antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Fórmula:C20H21D3O2Cor e Forma:NeatPeso molecular:299.42Betamethasone 17-Propionate
CAS:Produto Controlado<p>Impurity Clobetasol Propionate EP Impurity A / Betamethasone Dipropionate EP Impurity B<br>Applications Betamethasone 17-Propionate (Clobetasol Propionate EP Impurity A) is a degradation product of Betamethasone. Glucocorticoid.<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Fórmula:C25H33FO6Cor e Forma:Off-WhitePeso molecular:448.52Dutasteride β-Dimer
CAS:Produto Controlado<p>Applications Dutasteride β-Dimer is a dimer impurity of Dutasteride (D735000); a dual inhibitor of 5α-reductase isoenzymes type 1 and 2. Dutasteride is structurally related to Finasteride (F342000) and is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Fórmula:C46H55F6N3O4Cor e Forma:NeatPeso molecular:827.94Lynestrenol
CAS:Produto Controlado<p>Applications Lynestrenol is an orally available progestogen hormone used in contraception to avoid hereditary angiodema as well as in treatment of ischemic stroke.<br>References Saule, C. et al.: Clin. Exp. Allergy, 43, 475 (2013); Beraki, S. et al.: PLoS One., 8, e69233 (2013);<br></p>Fórmula:C20H28OCor e Forma:NeatPeso molecular:284.44Hydroxy Flutamide-d6
CAS:Produto ControladoFórmula:C11H5D6F3N2O4Cor e Forma:Light Yellow SolidPeso molecular:298.25
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