Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Foram encontrados 4949 produtos de "Esteroides e Derivados"
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4'-Nitro-3'-(trifluoromethyl)acetanilide
CAS:<p>Applications 4’-Nitro-3’-(trifluoromethyl)acetanilide is a metabolite of the nonsteroidal antiandrogen drug, Flutamide (F598850).<br>References Kang, P. et al.: Drug Metab. Dispos., 36, 1425 (2008); Takashima, E. et al.: Biol. Pharmac. Bull., 26, 1455 (2003); Katchen, B. et al.: J. Invest. Dermatol., 66, 379 (1976);<br></p>Fórmula:C9H7F3N2O3Cor e Forma:NeatPeso molecular:248.162-Methyl Ethynyl Estradiol
CAS:Produto Controlado<p>Impurity Ethinylestradiol EP Impurity M<br>Applications 2-Methylethynylestradiol (Ethinylestradiol EP Impurity M) is a 17α-ethynyl steroid. 2-Methylethynylestradiol is an impurity of Ethynylestradiol (E685100).<br></p>Fórmula:C21H26O2Cor e Forma:NeatPeso molecular:310.43a,a,a-Trifluorotoluene
CAS:Produto Controlado<p>Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);<br></p>Fórmula:C7H5F3Cor e Forma:ColourlessPeso molecular:146.116α-Hydroxy Testosterone-d3
CAS:Produto ControladoFórmula:C19H25D3O3Cor e Forma:NeatPeso molecular:307.44(11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione
CAS:Produto Controlado<p>Applications (11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione is a derivative of Dexamethasone (D298800), an anti-inflammatory glucocorticoid.<br>References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),<br></p>Fórmula:C22H27FO4Cor e Forma:WhitePeso molecular:374.45Betamethasone 21-Mesylate (>90%)
CAS:Produto ControladoFórmula:C23H31FO7SPureza:>90%Cor e Forma:NeatPeso molecular:470.55Fluocinolone Acetonide-13C3
CAS:Produto ControladoFórmula:C2113C3H30F2O6Cor e Forma:NeatPeso molecular:455.47Dexamethasone Phosphate Bisulfate Adduct Sodium Salt
CAS:Fórmula:C22H32FO11PS•xNaCor e Forma:NeatPeso molecular:554.522298Prednisolone (1 mg/mL in Methanol)
CAS:Produto ControladoFórmula:C21H28O5Cor e Forma:ColourlessPeso molecular:360.443β-Hydroxy Tibolone (1mg/ml in Acetonitrile)
CAS:Produto ControladoFórmula:C21H30O2Cor e Forma:Single SolutionPeso molecular:314.46Equilenin-d3
CAS:Produto Controlado<p>Applications Isotope labelled Equilenin (E592400), which is a naturally occuring estrogenic steroidal hormone (1,2) isolated from urine of pregnant mares (3). Not found in human urine. Component of conjugated estrogenic hormones. Estrogen. This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Corbellini, A. et L.: Farmaco Sci. 1964 Nov;19:913-22.2. Stein, R. et al.: Tetrahedron 1970 Apr;26(8):1917-33.<br></p>Fórmula:C182H3H15O2Cor e Forma:White To Light BrownPeso molecular:269.3517β-Dihydro Equilin-16,16,17-d3
CAS:Produto Controlado<p>Applications A labelled metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C182H3H17O2Cor e Forma:NeatPeso molecular:271.373-O-Benzyl Estriol
CAS:Produto Controlado<p>Applications Protected Estriol.<br>References Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Fórmula:C25H30O3Cor e Forma:NeatPeso molecular:378.506α-Hydroxy Gestrinone Glucuronide
CAS:Produto ControladoFórmula:C27H32O9Cor e Forma:Light YellowPeso molecular:500.5413-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (~90%) (Levo Norgestrel Impurity)
CAS:Produto Controlado<p>Impurity Levonorgestrel EP Impurity D<br>Applications 13-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (Levonorgestrel EP Impurity D) is an impurity of Levonorgestrel.<br>References McGinty, D., et al.: Endocrinology, 24, 829 (1939), Belanger, A., et al.: Steroids, 37, 361 (1981), Nieman, L., et al.: J. Clin. Endocrinol. Metab., 61, 536 (1985), Klebe, G., et al.: J. Med. Chem., 37, 4130 (1994),<br></p>Fórmula:C21H30OCor e Forma:NeatPeso molecular:298.464-Hydroxy Estradiol 1-N3-Adenine
CAS:Produto Controlado<p>Applications 4-Hydroxy Estradiol 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H27N5O3Cor e Forma:NeatPeso molecular:421.49b-Estradiol 17-Acetate
CAS:Produto Controlado<p>Applications Protected Estradiol. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References Miilunpohja, M., et al.: J. Steroid Biochem. Mol. Biol., 100, 59 (2006), Ikonomou, M., et al.: Environ. Toxicol. Chem., 27, 243 (2008),<br></p>Fórmula:C20H26O3Cor e Forma:NeatPeso molecular:314.427-[9-[[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17β
Produto Controlado<p>Applications Fulvestrant (F862500) impurity C.<br></p>Fórmula:C41H65F5O4S2Cor e Forma:NeatPeso molecular:781.073-Aminobenzotrifluoride
CAS:Produto Controlado<p>Applications 3-Aminobenzotrifluoride is a known human toxin that can cause bacterial mutation and hepatocyte unscheduled DNA synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reinhold, D., et al.: T. ASAE, 49, 2077 (2006); Thompson, C., et al.: Environ. Mutagen., 5, 803 (1983)<br></p>Fórmula:C7H6F3NCor e Forma:YellowPeso molecular:161.1225-Hydroxy Cholesterol-d6
CAS:Produto Controlado<p>Applications 25-Hydroxy Cholesterol-d6, is the labeled analogue of 25-Hydroxy Cholesterol (H918030), which is an oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It also induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.<br>References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);<br></p>Fórmula:C272H6H40O2Cor e Forma:NeatPeso molecular:408.697-(Desacetothioxy)-7-acetodithioperoxy-spironolactone
Produto ControladoFórmula:C24H32O4S2Cor e Forma:NeatPeso molecular:448.646a,9a-Difluoroprednisolone
CAS:Produto Controlado<p>Applications 6α,9α-Difluoroprednisolone has shown to increase metastases and increase glucocorticoid activity in C57/BL6 mice.<br>References Albert, D., Zeidman, I.: Cancer Res., 22, 1297 (1962)<br></p>Fórmula:C21H26F2O5Cor e Forma:White To Light BeigePeso molecular:396.4210b-Hydroxy D-(-)-Norgestrel
CAS:<p>Applications 10β-Hydroxy D-(-)-Norgestrel is an impurity of Levonorgestrel (N689510).<br>References Gorog, S. et al.: J. Pharmac. Biomed. Anal., 14, 85 (1995); Berta, R. et al.: J. Pharmac. Biomed. Anal., 54, 458 (2011); Choudhary, M. I. et al.: Nat. Prod. Res., 20, 1074 (2006);<br></p>Fórmula:C21H28O3Cor e Forma:White To Off-WhitePeso molecular:328.4452-Hydroxy Atorvastatin Lactone
CAS:Produto Controlado<p>Impurity Atorvastatin 2-Hydroxy Lactone<br>Stability Hygroscopic<br>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br></p>Fórmula:C33H33FN2O5Cor e Forma:Off White SolidPeso molecular:556.6215-Keto Latanoprost
CAS:<p>Applications 15-Keto Latanoprost is a metabolite of Latanoprost (L177280).<br>References Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998), Watson, P., et al.: Drugs Today, 35, 449 (1999),<br></p>Fórmula:C23H30O5Cor e Forma:NeatPeso molecular:386.48Testosterone-16,16,17-d3 Benzoate
CAS:Produto ControladoFórmula:C26H29D3O3Cor e Forma:NeatPeso molecular:395.562-Hydroxy-estrone-6-N3-adenine (90%)
CAS:Produto Controlado<p>Applications 2-Hydroxy-estrone-6-N3-adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Fórmula:C23H25N5O3Pureza:90%Cor e Forma:NeatPeso molecular:419.48Estratetraenol
CAS:Produto Controlado<p>Applications A steroid produced by females having pheromone activities.<br>References Kotiyan, P., et al.: J. Pharm. Biomed. Anal., 22, 667 (2000), Bensafi, M., et al.: Behaviour. Brain Res., 152, 11 (2004), Zhu, B., et al.: Endocrinol., 147, 4132 (2006), Bellavance, E., et al.: J. Med. Chem., 52, 7488 (2009),<br></p>Fórmula:C18H22OCor e Forma:NeatPeso molecular:254.374-Methylestrone
CAS:Produto Controlado<p>Applications 4-Methylestrone is an intermediate in the synthesis of 4-substituted estrone and estradiol derivatives with inhibitory activities towards steroid sulfatase as a target for therapeutic intervention of treating breast cancer.<br>References Numazawa, M., et al.: J. Steroid. Biochem. Molec. Biol., 96, 51 (2005);<br></p>Fórmula:C19H24O2Cor e Forma:NeatPeso molecular:284.39Fluticasone-d3 17β-Carboxylic Acid
CAS:Produto ControladoFórmula:C21H23D3F2O5Cor e Forma:NeatPeso molecular:399.44Tetrahydrocortisol 21-Acetate
CAS:Produto Controlado<p>Applications Cortisol derivative. A potential corticoid metabolite.<br>References Okihara, R. et al.; Chem. Pharm. Bull. 58, 344 (2010); Hosoda, H. et al.; Chem. Pharm. Bull. 32, 4023 (1984)<br></p>Fórmula:C23H36O6Cor e Forma:NeatPeso molecular:408.53(3E)-17-Deacetylnorgestimate
CAS:<p>Applications E-17-Deacetylnorgestimate is a metabolite of Norgestimate. A contraceptive for birth control used by women.Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990); Rabiolo, A., et al.: Arch. Gynecol. Obstet., 294, 1317 (2016)<br></p>Fórmula:C21H29NO2Cor e Forma:Off-WhitePeso molecular:327.46Desisobutyryl Ciclesonide
CAS:Produto Controlado<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Fórmula:C28H38O6Cor e Forma:White To Off-WhitePeso molecular:470.606-Oxo Boldione
CAS:Produto Controlado<p>Applications A derivative of Exemestane (E957000), a new aromatase inhibitor.<br>References Thompson, E., et al.: J. Biol. Chem., 249, 5364 (1974), Cole, P., et al.: J. Med. Chem., 33, 2933 (1990), Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Fórmula:C19H22O3Cor e Forma:Off-White To Light YellowPeso molecular:298.38Cholesterol 5α,6α-Epoxide
CAS:Produto Controlado<p>Applications Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols.<br>References Lizard, G., et al.: Eur. J. Lipid Sci. Technol., 118, 135 (2016); Sabolova, M., et al.: J. Sci. Food Agric., 97, 5092 (2017); Bezine, M., et al.: Biochimie (2018)<br></p>Fórmula:C27H46O2Cor e Forma:NeatPeso molecular:402.65Ciclesonide-d7
CAS:Produto Controlado<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References ukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Fórmula:C32H37D7O7Cor e Forma:NeatPeso molecular:547.73(5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one
CAS:Produto Controlado<p>Applications (5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one is metabolite and impurity of the anabolic steroid Oxandrolone (O845050).<br>References Fragkaki, A.G. et al.: J. Steroid Biochem. Mol. Biol., 115, 44 (2009); Bi, H. et al.: J. Steroid Biochem. Mol. Biol., 42, 533 (1992);<br></p>Fórmula:C19H28O2Cor e Forma:White To Off-WhitePeso molecular:288.4217-Hydroxypregn-5-ene-3,20-dione
CAS:Produto Controlado<p>Applications 17-Hydroxypregn-5-ene-3,20-dione is used in the synthesis of physiologically active steroid esters and spirolactones that functions as potential aldosterone antagonists.<br>References Seletskii, B. M., et al.: Croat. Chem. Acta. , 58, 699 (1986)<br></p>Fórmula:C21H30O3Cor e Forma:NeatPeso molecular:330.463-epi-25-Hydroxy Vitamin D3
CAS:<p>Stability Light Sensitive, Temperature Sensitive<br>Applications The epimer metabolite of Calcifediol or 25-hydroxyvitamin D3 (C125700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sakaki, T., et al.: Eur. J. Biochem., 267, 6158 (2000), Kamao, M., et al.: J. Biol. Chem., 278, 1463 (2003),<br></p>Fórmula:C27H44O2Cor e Forma:NeatPeso molecular:400.6421-Butyryloxy Budesonide
<p>Applications 21-Butyryloxy Budesonide is a derivative of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979); Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980); Clissold, S.P., et al.: Drugs, 28, 485 (1984)<br></p>Fórmula:C29H40O7Cor e Forma:NeatPeso molecular:500.62Atorvastatin Lactone Diepoxide(Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An Atorvastatin (A791750) derivative which have improved stability.<br></p>Fórmula:C33H33FN2O6Cor e Forma:NeatPeso molecular:572.6217β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide
CAS:Produto Controlado<p>Applications 17β-Hydroxy Exemestane 17-O-β-D-Glucuronide is the glucuronidated conjugate of the hydroxy metabolite of Exemestane (E957000).<br>References Sun, D. et al.: Pharmacogen. Genom., 20, 575 (2010);<br></p>Fórmula:C26H31D3O8Cor e Forma:NeatPeso molecular:477.562-Hydroxy Estradiol 6-N3-Adenine
CAS:Produto Controlado<p>Applications 2-Hydroxy Estradiol 6-N3-Adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogeneous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Fórmula:C23H27N5O3Cor e Forma:NeatPeso molecular:421.49Fulvestrant 17-Ketone
CAS:Produto Controlado<p>Applications Fulvestrant 17-Ketone, is an impurity of Fulvestrant (F862500), a novel steroidal estrogen antagonist reported to lack any partial agonist activity. Antineoplastic (hormonal).<br>References Wakeling, A.E., et al.: Cancer Res., 51, 3867 (1991), Howell, A., et al.: Br. J. Cancer, 74, 300 (1996), Robertson, J.F., et al.: Cancer Res., 61, 6739 (2001),<br></p>Fórmula:C32H45F5O3SCor e Forma:NeatPeso molecular:604.75(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
CAS:Produto Controlado<p>Applications Glucocorticoid.<br></p>Fórmula:C22H28O4Cor e Forma:NeatPeso molecular:356.466b-Chloro-7a-hydroxy-6,7-dihydro Cyproterone Acetate
CAS:Produto Controlado<p>(1β,2β,6β-7α)-17-(Acetyloxy)-6-chloro-1,2-dihydro-7-hydroxy<br>-3'H-cyclopropa[1,2]pregna-1,4-diene-3,20-dione; 6β-Chloro<br>-1β,2β-dihydro-7α,17-dihydroxy-3'Hcyclopropa[1,2]pregna-1,4-diene-3,20-dione 17-Acetate;<br>Cyproterone Acetate EP Impurity G</p>Fórmula:C24H31ClO5Cor e Forma:NeatPeso molecular:434.9537α-Acetylthio-17α-ethoxymethyl Testosterone
CAS:Produto ControladoFórmula:C24H36O4SCor e Forma:NeatPeso molecular:420.61
![7-[9-[[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17β](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FP227275.webp&w=3840&q=75)
