Fosfatos e Fosfonatos Orgânicos
Os fosfatos orgânicos são compostos que contêm um grupo fosfato (-PO₄) ligado a um átomo de carbono numa estrutura orgânica, geralmente em combinação com álcoois, ácidos ou aminas. Estes compostos são utilizados na formulação de APIs para melhorar a solubilidade, estabilidade e biodisponibilidade dos princípios ativos. Os fosfatos orgânicos também desempenham um papel na liberação controlada de fármacos e na melhoria da absorção de certos medicamentos.
Os fosfonatos orgânicos contêm um grupo fosfonato (-PO₃H₂), no qual o átomo de fósforo está ligado a um átomo de carbono e a dois grupos oxigênio. Estes compostos possuem propriedades farmacológicas importantes, especialmente na inibição de enzimas e na modulação de processos bioquímicos. Os fosfonatos orgânicos são utilizados na produção de APIs que atuam no metabolismo ósseo, no tratamento de infecções bacterianas ou como antivirais, devido aos seus efeitos biológicos específicos.
Na CymitQuimica, oferecemos fosfatos e fosfonatos orgânicos para pesquisa em química médica, bioquímica e desenvolvimento de formulações avançadas.
Foram encontrados 1201 produtos de "Fosfatos e Fosfonatos Orgânicos"
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Diatrizoic Acid Dihydrate
CAS:<p>Diatrizoic Acid Dihydrate is used as a radiocontrast compound. It is used for imaging the gastrointestinal tract in patients allergic to barium.</p>Fórmula:C11H13I3N2O6Cor e Forma:SolidPeso molecular:649.943α-Hydroxy Pravastatin Lactone-d3
CAS:Produto Controlado<p>Applications A labelled metabolite of Pravastatin (P702000), a competitive inhibitor of HMG-CoA reductase.<br>References Serizawa, N., et al.: J. Antibiot., 36, 604 (1983), White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)<br></p>Fórmula:C23H31D3O6Cor e Forma:NeatPeso molecular:409.53Zofenoprilat Sodium Salt (90%)
CAS:<p>Stability Very Hygroscopic<br>Applications The active metabolite of Zofenopril, an ACE inhibitor.<br>References Cushman, D., et al.: Br. J. Clin. Pharmacol., 28, 115S (1989), Kelly, J., et al.: Clin. Pharmacokinet., 19, 177 (1990), Liu, X., et al.: Cardiv. Drugs Ther., 6, 437 (1992), Marzo, A., et al.: Arzneim.- Forsch., 49, 992 (1999), Subissi, A., et al.: Cardiv. Drug Rev., 17, 2 (1999),<br></p>Fórmula:C15H18NNaO3S2Pureza:90%Cor e Forma:White SolidPeso molecular:347.433-Bromo-2-methylpropionic Acid
CAS:<p>Impurity Captopril EP Impurity D<br>Stability Hygroscopic<br>Applications 3-Bromo-2-methylpropionic Acid (Captopril EP Impurity D) is used in the preparation of captopril selenium analogs as antioxidants and ACE inhibitors used as antihypertensive drugs.<br>References Bhuyan, B. et al.: Org. Biomol. Chem., 9, 1356 (2011);<br></p>Fórmula:C4H7BrO2Cor e Forma:Colourless LiquidPeso molecular:167.003,3'-Disulfanediylbis[(2S)-2-methylpropanoic] Acid
CAS:Produto ControladoFórmula:C8H14O4S2Cor e Forma:NeatPeso molecular:238.32Deferasirox-d4
CAS:Produto Controlado<p>Applications Labelled orally active tridentate iron chelator.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hershko, C., et al.: Blood, 97, 1115 (2001), Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003), Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003),<br></p>Fórmula:C212H4H11N3O4Cor e Forma:NeatPeso molecular:377.39Minodronic Acid
CAS:Produto Controlado<p>Applications Minodronic acid is developed for osteoporosis treatment.<br>References Tanishima, S., et al.: Clin. Interv. Aging, 8, 185 (2013)<br></p>Fórmula:C9H12N2O7P2Cor e Forma:NeatPeso molecular:322.15Malathion (Diethyl-d10)
CAS:Produto Controlado<p>Applications Malathion (Diethyl-d10) is used as one of the substances for the clean-up step in post-harvest pesticide residue analysis.<br>References Ucles, A., et al.: Talanta, 144, 51 (2015)<br></p>Fórmula:C102H10H9O6PS2Cor e Forma:Light YellowPeso molecular:340.42Hydroxy Cyclophosphamide Semicarbazone-d4 (>80%)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Isotope labelled Aldophosphamide Semicarbazone is a major metabolite of cyclophosphamide (C988580), a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.<br>References Struck, R.F., et al.: Cancer. Rsch., 34, 2933 (1947); Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999),<br></p>Fórmula:C8H14D4Cl2N5O3PPureza:>80%Cor e Forma:NeatPeso molecular:338.16Fenthion Sulfone-d6
CAS:Produto Controlado<p>Applications Labelled Fenthion Sulfone (F278015). Fenthion Sulfone is a metabolite of the organothiophosphate insecticide Fenthion (F278000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Oh, C., et al.: Bull Environ. Contam. Toxicol., 78, 314 (2007); Wang, W., et al.: Anal. Chim. Acta, 602, 211 (2007);<br></p>Fórmula:C10H9D6O5PS2Cor e Forma:NeatPeso molecular:316.36N-Nitroso Cilazapril (Phenyl-D5)
CAS:Produto ControladoFórmula:C22D5H25N4O6Cor e Forma:NeatPeso molecular:451.528m-Salicylic Acid
CAS:Produto Controlado<p>Applications m-Salicylic Acid is widely used in organic synthesis. It is also an important active metabolite of aspirin (A187780).<br>References Haynes, M., et al.: CRC H.b Chem. Phys., 92, 306 (2011)<br></p>Fórmula:C7H6O3Cor e Forma:Off-WhitePeso molecular:138.12Hydroxy Cyclophosphamide Semicarbazone (80%)
CAS:Produto Controlado<p>Applications Aldophosphamide Semicarbazone is a major metabolite of cyclophosphamide (C988580), a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.<br>References Struck, R.F., et al.: Cancer. Rsch., 34, 2933 (1947); Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962); Fraiser, L.H., et al.: Drugs, 42, 781 (1991); Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999);<br></p>Fórmula:C8H18Cl2N5O3PPureza:80%Cor e Forma:NeatPeso molecular:334.14Captopril EP Impurity N
CAS:<p>Captopril EP Impurity N is a synthetic impurity found in Captopril EP, which is used as a drug product for the treatment of hypertension. The impurity standard for Captopril EP Impurity N is available on request.</p>Fórmula:C8H14O4S2Pureza:Min. 95%Peso molecular:238.33 g/molEnalaprilat benzyl ester
CAS:<p>Enalaprilat benzyl ester is a drug product that is custom synthesized according to the customer's specifications. It is a white or off-white crystalline powder and has a purity of 99%. Enalaprilat benzyl ester is used in the development of drugs, research and development, and analytical studies. It can be used as an impurity standard to test for enalaprilat in pharmaceutical products. It can also be used as a metabolite standard to measure blood levels of enalaprilat.</p>Fórmula:C25H30N2O5Pureza:Min. 95%Peso molecular:438.52 g/molCalcipotriol EP Impurity I
<p>Calcipotriol EP Impurity I is a metabolite of calcipotriol which acts as a natural, synthetic and analytical standard for the compound. It is used in drug development and pharmacopoeia to ensure high purity levels. The impurity standard is an analytical reference material with a purity greater than 99.5% and contains no more than 10% of any other impurity.</p>Fórmula:C27H40O3Pureza:Min. 95%Peso molecular:412.6 g/mol(S)-3''-Hydroxy pravastatin sodium salt
CAS:<p>(S)-3''-Hydroxy pravastatin sodium salt is a drug product that is custom synthesized. It is the sodium salt of (S)-3''-hydroxypravastatin, which has been shown to be a natural product with high purity. The metabolite of (S)-3''-hydroxypravastatin sodium salt is 3'-hydroxypravastatin. This product can be used for analytical purposes as well as in pharmacopoeia, drug development, and research and development. It can also be used as an impurity standard for HPLC and GC analysis.</p>Fórmula:C23H35NaO8Pureza:Min. 95%Peso molecular:462.51 g/molPravastatin 6-oxo Impurity
CAS:<p>Pravastatin 6-oxo Impurity is an impurity of Pravastatin, a drug used in the treatment of high cholesterol. The impurity has been identified through analytical methods and is characterized by HPLC analysis. This substance has been shown to be present in at least 0.1% of the drug product and may be present as a result of incomplete synthesis or a side-reaction during synthesis.</p>Fórmula:C23H34O7Pureza:Min. 95%Peso molecular:422.51 g/mol3α-Hydroxy pravastatin sodium salt
CAS:<p>3alpha-Hydroxy pravastatin sodium salt is a white to off-white crystalline powder. It is used as an analytical standard for 3alpha-hydroxypravastatin and its metabolites. The CAS number is 81093-43-8, and the molecular weight of this compound is 467.6 g/mol. This product can be custom synthesized to meet your needs.</p>Fórmula:C23H35NaO7Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:446.51 g/mol
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