Nucleosídeos e Nucleotídeos
Os nucleosídeos são compostos formados por uma base nitrogenada ligada a um açúcar (ribose ou desoxirribose). Quando um grupo fosfato é adicionado ao nucleosídeo, forma-se um nucleotídeo. Esses compostos são essenciais na biologia celular, pois os nucleotídeos são os blocos fundamentais do DNA e RNA, responsáveis pelo armazenamento e transmissão da informação genética. Os nucleosídeos têm aplicações no tratamento de doenças virais, atuando como inibidores da replicação viral. Os nucleotídeos, além do seu papel estrutural nos ácidos nucleicos, participam de processos energéticos, como a síntese de ATP.
Na CymitQuimica, oferecemos uma ampla gama de nucleosídeos e nucleotídeos essenciais para pesquisa em biologia molecular, virologia e farmacologia.
Foram encontrados 3430 produtos de "Nucleosídeos e Nucleotídeos"
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Dexelvucitabine
CAS:<p>Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C9H10FN3O3Pureza:98.25%Cor e Forma:SolidPeso molecular:227.19Cidofovir dihydrate
CAS:<p>Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.</p>Fórmula:C8H18N3O8PPureza:99.44%Cor e Forma:SolidPeso molecular:315.22Fludarabine Phosphate
CAS:Fludarabine Phosphate (NSC 312887 Phosphate) is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine with antineoplastic activity.Fórmula:C10H13FN5O7PPureza:99.25% - 99.78%Cor e Forma:SolidPeso molecular:365.21Hibifolin
CAS:Hibifolin is a flavonol glycoside natural product,is a potential inhibitor of adenosine deaminase (Ki of 49.92 μM).Fórmula:C21H18O14Pureza:98.92%Cor e Forma:SolidPeso molecular:494.361,5-Isoquinolinediol
CAS:1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.Fórmula:C9H7NO2Pureza:98.29% - 99.35%Cor e Forma:Of White To White PowderPeso molecular:161.16Dilazep dihydrochloride
CAS:<p>Dilazep dihydrochloride inhibits adenosine uptake, ischemia, nucleoside transport, platelet aggregation, and acts as a vasodilator.</p>Fórmula:C31H46Cl2N2O10Pureza:98.39%Cor e Forma:SolidPeso molecular:677.61Remdesivir
CAS:<p>Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of</p>Fórmula:C27H35N6O8PPureza:97.62% - 99.98%Cor e Forma:SolidPeso molecular:602.58Uridine
CAS:<p>Uridine (Uridin) is a nucleoside compound, a base that makes up RNA, that replaces thymine in DNA during transcriptione. Cost-effective and quality-assured.</p>Fórmula:C9H12N2O6Pureza:99.08% - 99.82%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:244.2Adenosine monophosphate
CAS:AMP is a purine nucleotide, vital in cell signaling and energy regulation, and inhibits EC 3.1.3.11 and 3.1.3.1, also an A1 receptor agonist.Fórmula:C10H14N5O7PPureza:99.59% - 99.84%Cor e Forma:Crystals From Water + Acetone SolidPeso molecular:347.22GKT136901
CAS:GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of PeroxynitriteFórmula:C19H15ClN4O2Pureza:99.16%Cor e Forma:SolidPeso molecular:366.8NADPH tetrasodium salt
CAS:<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Fórmula:C21H26N7Na4O17P3Pureza:97.15% - >99.99%Cor e Forma:SolidPeso molecular:833.35NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Fórmula:C45H82N11O17P3Pureza:98.73% - 99.05%Cor e Forma:SolidPeso molecular:1142.12Thiamine pyrophosphate chloride
CAS:<p>Thiamine pyrophosphate, a vitamin B1 derivative, is a coenzyme in transketolase studies for decarboxylation in biology.</p>Fórmula:C12H19ClN4O7P2SPureza:98.29% - 99.72%Cor e Forma:SolidPeso molecular:460.76ASP-9521
CAS:<p>ASP-9521 is a selective, potent and orally active indole-based AKR1C3 inhibitor with an IC50 of 11 nM for human AKR1C3.Cost-effective and quality-assured.</p>Fórmula:C19H26N2O3Pureza:95.11% - 96.96%Cor e Forma:SolidPeso molecular:330.42Rabeprazole sodium
CAS:<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Fórmula:C18H20N3NaO3SPureza:98% - 99.912%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:381.42Ganciclovir sodium
CAS:Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.Fórmula:C9H13N5NaO4Pureza:99.93%Cor e Forma:SolidPeso molecular:278.22Didanosine
CAS:<p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>Fórmula:C10H12N4O3Pureza:99.64%Cor e Forma:White Crystalline PowderPeso molecular:236.23Cytosine
CAS:Cytosine is a pyrimidine nucleic acid base; its deamination can cause mutations in leukemia and cancer.Fórmula:C4H5N3OPureza:99.67%Cor e Forma:SolidPeso molecular:111.1Sofosbuvir
CAS:<p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>Fórmula:C22H29FN3O9PPureza:99.77% - 99.82%Cor e Forma:SolidPeso molecular:529.45Cytidine 5'-monophosphate
CAS:<p>Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide, one of the basic units that make up RNA.</p>Fórmula:C9H14N3O8PPureza:98.78% - 99.10%Cor e Forma:SolidPeso molecular:323.20N2-Nitroso Folinic Acid (N2-Nitroso (6RS)-Calcium Levofolinate EP Impurity H, N2-Nitroso Leucovorin)
Fórmula:C20H22N8O8Peso molecular:502.44Famciclovir
CAS:Produto Controlado<p>Applications Used as an antiviral. Prodrug of Penciclovir (P221500).<br>References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),<br></p>Fórmula:C14H19N5O4Cor e Forma:Off-WhitePeso molecular:321.33N-Nitrosodiethylamine (100 ug/mL in Methanol)
CAS:Produto ControladoFórmula:C4H10N2OCor e Forma:Single SolutionPeso molecular:102.14Ribavirin-13C5
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled Ribavirin (R414475). Purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Fórmula:C5C3H12N4O5Cor e Forma:NeatPeso molecular:249.17Entecavir-13C2,15N
CAS:Produto Controlado<p>Applications Labelled Entecavir. An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.<br>References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),<br></p>Fórmula:C1013C2H15N415NO3Cor e Forma:White To Off-WhitePeso molecular:280.264’-Epi Lamivudine
CAS:Produto Controlado<p>Applications Lamivudine epimer.<br>References Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992), Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Fórmula:C8H11N3O3SCor e Forma:NeatPeso molecular:229.26Adenosine-13C5
CAS:<p>Stability Hygroscopic<br>Applications Labelled nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010), Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010),<br></p>Fórmula:C513C5H13N5O4Cor e Forma:White To Off-WhitePeso molecular:272.20RO 2433
CAS:Produto Controlado<p>Impurity Sofosbuvir Metabolite GS331007<br>Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.<br>References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)<br></p>Fórmula:C10H13FN2O5Cor e Forma:NeatPeso molecular:260.223’,5’-Di-O-benzyl Entecavir
CAS:Produto Controlado<p>Applications 3’,5’-Di-O-benzyl Entecavir is an intermediate in the preparation of the hepatitis B antiviral agent, Entecavir (E558900).<br>References Li, R. et al.: Zhong. Yao., 6, 292 (2008); Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);<br></p>Fórmula:C26H27N5O3Cor e Forma:NeatPeso molecular:457.52cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS:Produto Controlado<p>Applications Antiviral nucleoside analog, also an impurity found in emtricitabine (E525000).<br>References Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Fórmula:C8H9FN2O4SCor e Forma:Off-WhitePeso molecular:248.23α-Decitabine-3',5'-bis(4-chlorobenzoate)
CAS:Produto ControladoFórmula:C22H18Cl2N4O6Cor e Forma:White To Off-WhitePeso molecular:505.308Folic Acid-13C5
CAS:<p>Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>Fórmula:C5C14H19N7O6Cor e Forma:Dark Yellow To Dark BrownPeso molecular:446.362-Oxa-1,4-butanediol diacetate
CAS:Produto ControladoFórmula:C7H12O5Cor e Forma:NeatPeso molecular:176.17trans-Abacavir Dihydrochloride
CAS:Produto Controlado<p>Applications trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Fórmula:C14H18N6O·2HClCor e Forma:NeatPeso molecular:359.25Adenosine 5’-Monophosphoramidate Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Used in the characterization and elucidation of coordination requirements of adenine nucleotides complexes with Fe(II) ions.<br>References Richter, Y., et al.: Nucleos. Nucleot. Nucleic Acids, 22, 1757 (2003),<br></p>Fórmula:C10H14N6O6P·NaCor e Forma:NeatPeso molecular:368.22O-Benzoyllamivudine
CAS:Produto ControladoFórmula:C15H15N3O4SCor e Forma:Off-WhitePeso molecular:333.3625-Fluoro Cytosine
CAS:Produto Controlado<p>Applications 5-FC is a toxic antifungal/antimicrobial agent.<br>References Gopinath, P., et al.: Biotechnol. Lett., 30, 1913 (2008), Kalkanci, A., et al.: Microbiol Immunol., 52, 435 (2008), Dubeau, M., et al.: App. Env. Microbiol., 75, 1211 (2009),<br></p>Fórmula:C4H4FN3OCor e Forma:White To Off-WhitePeso molecular:129.09Penciclovir
CAS:<p>Applications An antiviral.<br>References Weinberg, A., et al.: Antimicrob. Ag. Chemother., 36, 2037 (1992), McMeekin, J.R., et al.: Anal. Proc., 29, 178 (1992),<br></p>Fórmula:C10H15N5O3Cor e Forma:NeatPeso molecular:253.26N2-Acetyl Acyclovir
CAS:Produto Controlado<p>Impurity Aciclovir EP Impurity F<br>Applications N2-Acetyl Acyclovir (Aciclovir EP Impurity F) is an impurity of Acyclovir (A192400).<br>References Balon, K., et al.: Pharm. Res., 16, 882 (1999),<br></p>Fórmula:C10H13N5O4Cor e Forma:BeigePeso molecular:267.245-Fluoro ent-Lamivudine Acid D-Menthol Ester
CAS:Produto Controlado<p>Applications Intermediate in the synthesis of ent-Emtricitabine (E525005).<br></p>Fórmula:C18H26FN3O4SCor e Forma:NeatPeso molecular:399.48
![cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FF591850.webp&w=3840&q=75)
