Nucleosídeos e Nucleotídeos
Os nucleosídeos são compostos formados por uma base nitrogenada ligada a um açúcar (ribose ou desoxirribose). Quando um grupo fosfato é adicionado ao nucleosídeo, forma-se um nucleotídeo. Esses compostos são essenciais na biologia celular, pois os nucleotídeos são os blocos fundamentais do DNA e RNA, responsáveis pelo armazenamento e transmissão da informação genética. Os nucleosídeos têm aplicações no tratamento de doenças virais, atuando como inibidores da replicação viral. Os nucleotídeos, além do seu papel estrutural nos ácidos nucleicos, participam de processos energéticos, como a síntese de ATP.
Na CymitQuimica, oferecemos uma ampla gama de nucleosídeos e nucleotídeos essenciais para pesquisa em biologia molecular, virologia e farmacologia.
Foram encontrados 3429 produtos de "Nucleosídeos e Nucleotídeos"
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4-Desethoxy-2-ethoxy Dapagliflozin, >90%
CAS:Produto Controlado<p>Applications (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(2-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol is an impurity of Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Fórmula:C21H25ClO6Pureza:>90%Cor e Forma:NeatPeso molecular:408.87Abacavir 5’-β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Abacavir 5’-β-D-Glucuronide is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Fórmula:C20H25N6NaO7Cor e Forma:NeatPeso molecular:484.44Fenretinide
CAS:Produto Controlado<p>Stability Light Sensitive - Protect from Light Exposure<br>Applications Fenretinide (4-HPR) is a synthetic retinoid deriverative. 4-HBR is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.A synthetic analog of Vitamin A.<br>References Marth, C., et al.:J. Nat. Cancer Inst., 75, 871 (1985), Delia, D., et al.: Cancer Res., 53, 6036 (1993), Costa., A., et al.: Cancer Res., 54, Suppl., 2032s (1994), Decensi., A., et al.: Eur. J. Cancer Prev., 3, 377 (1994)<br></p>Fórmula:C26H33NO2Cor e Forma:NeatPeso molecular:391.551-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications 1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one is an impurity of 5-Azacytidine (A796000), a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase.<br>References Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999), Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999), Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999), Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)<br></p>Fórmula:C10H14N4O6Cor e Forma:White To Off-WhitePeso molecular:286.24Capecitabine
CAS:Produto Controlado<p>Applications Capecitabine is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).<br>References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Fórmula:C15H22FN3O6Cor e Forma:NeatPeso molecular:359.35N,O-Diacetate Isoacyclovir
CAS:Produto Controlado<p>Impurity Aciclovir EP Impurity M<br>Applications An impurity of Acyclovir. Aciclovir EP Impurity M<br>References Laskin, O., et al.: Clin. Pharmacok., 8, 187 (1983), Grass, G., et al.: Pharm. Res., 5, 372 (1988), Mahony, W., et al.: J. Biol. Chem., 263, 9285 (1988), Merino, V., et al.: J. Pharm. Sci., 84, 777 (1995),<br></p>Fórmula:C12H15N5O5Cor e Forma:NeatPeso molecular:309.2785’-Ethylcarboxamido Adenosine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A potent adenosine receptor agonist. Inhibits platelet aggregation and is centrally active in vivo.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cusack and Hourani: Br. J. Pharmacol., 72, 433 (1981), Knapp, et al.: Pharmacol. Biochem. Behav., 68, 797 (2001)<br></p>Fórmula:C12H16N6O4Cor e Forma:NeatPeso molecular:308.29Cidofovir Diphosphate Trisodium Salt (>85%)
CAS:Produto Controlado<p>Applications Cidofovir Diphosphate Trisodium Salt has antiviral activity, which is used against herpes viruses. Cidofovir Diphosphate is a metabolite in human cells.<br>References Hitchcock, M. J. M., et al.: Antivir. Chem. Chemoth., 7, 115-127 (1996); Cihlar, T., et al.: Collect. Czech. Chem. C., 57, 661-72 (1992)<br></p>Fórmula:C8H13N3Na3O12P3Pureza:>85%Cor e Forma:NeatPeso molecular:505.0925-Methyluridine
CAS:<p>Applications A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.<br>References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),<br></p>Fórmula:C10H14N2O6Cor e Forma:NeatPeso molecular:258.23Adenosine 5'-Monophosphate
CAS:Produto Controlado<p>Applications Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.<br>References Hong, J.A. et al.: J. Med. Chem., 52, 5485 (2009); Korboukh I. et al.: J. Med. Chem., 55, 6467 (2012)<br></p>Fórmula:C10H14N5O7PCor e Forma:NeatPeso molecular:347.225-Methyl-2’-deoxy Cytidine
CAS:<p>Applications A Cytidine (C998300) analog and also an isostere of Thymidine (T412000).<br>References Sabini, E., et al.: J. Med. Chem., 51, 4219 (2008), Sabini, E., et al.: J. Mol. Biol., 378, 607 (2008),<br></p>Fórmula:C10H15N3O4Cor e Forma:NeatPeso molecular:241.243’-Amino-3’-deoxythymidine
CAS:Produto Controlado<p>Impurity Zidovudine Impurity;<br>Stability Hygroscopic, Moisture Sensitive<br>Applications A metabolite of Zidovudine (3'-Azido-3'-deoxythymidine; AZT).<br>References Qian, M., et al.: Biochem. Pharmacol., 48, 383 (1994), Diwan, B., et al.: Toxicol. Appl. Pharmacol., 161, 82 (1999) , Lim, S., et al.: J. Biol. Chem., 276, 23616 (2001), Von Tungeln, L., et al.: Carcinogenesis, 23, 1427 (2002),<br></p>Fórmula:C10H15N3O4Cor e Forma:White To Off-WhitePeso molecular:241.24Entecavir-13C2,15N
CAS:Produto Controlado<p>Applications Labelled Entecavir. An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.<br>References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),<br></p>Fórmula:C1013C2H15N415NO3Cor e Forma:White To Off-WhitePeso molecular:280.264’-Epi Lamivudine
CAS:Produto Controlado<p>Applications Lamivudine epimer.<br>References Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992), Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Fórmula:C8H11N3O3SCor e Forma:NeatPeso molecular:229.26RO 2433
CAS:Produto Controlado<p>Impurity Sofosbuvir Metabolite GS331007<br>Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.<br>References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)<br></p>Fórmula:C10H13FN2O5Cor e Forma:NeatPeso molecular:260.223’,5’-Di-O-benzyl Entecavir
CAS:Produto Controlado<p>Applications 3’,5’-Di-O-benzyl Entecavir is an intermediate in the preparation of the hepatitis B antiviral agent, Entecavir (E558900).<br>References Li, R. et al.: Zhong. Yao., 6, 292 (2008); Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);<br></p>Fórmula:C26H27N5O3Cor e Forma:NeatPeso molecular:457.52cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS:Produto Controlado<p>Applications Antiviral nucleoside analog, also an impurity found in emtricitabine (E525000).<br>References Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Fórmula:C8H9FN2O4SCor e Forma:Off-WhitePeso molecular:248.23Folic Acid-13C5
CAS:<p>Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>Fórmula:C5C14H19N7O6Cor e Forma:Dark Yellow To Dark BrownPeso molecular:446.362-Oxa-1,4-butanediol diacetate
CAS:Produto ControladoFórmula:C7H12O5Cor e Forma:NeatPeso molecular:176.17trans-Abacavir Dihydrochloride
CAS:Produto Controlado<p>Applications trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Fórmula:C14H18N6O·2HClCor e Forma:NeatPeso molecular:359.25Adenosine 5’-Monophosphoramidate Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Used in the characterization and elucidation of coordination requirements of adenine nucleotides complexes with Fe(II) ions.<br>References Richter, Y., et al.: Nucleos. Nucleot. Nucleic Acids, 22, 1757 (2003),<br></p>Fórmula:C10H14N6O6P·NaCor e Forma:NeatPeso molecular:368.22O-Benzoyllamivudine
CAS:Produto ControladoFórmula:C15H15N3O4SCor e Forma:Off-WhitePeso molecular:333.362N2-Acetyl Acyclovir
CAS:Produto Controlado<p>Impurity Aciclovir EP Impurity F<br>Applications N2-Acetyl Acyclovir (Aciclovir EP Impurity F) is an impurity of Acyclovir (A192400).<br>References Balon, K., et al.: Pharm. Res., 16, 882 (1999),<br></p>Fórmula:C10H13N5O4Cor e Forma:BeigePeso molecular:267.245-Fluoro ent-Lamivudine Acid D-Menthol Ester
CAS:Produto Controlado<p>Applications Intermediate in the synthesis of ent-Emtricitabine (E525005).<br></p>Fórmula:C18H26FN3O4SCor e Forma:NeatPeso molecular:399.486-Deoxypenciclovir
CAS:Produto Controlado<p>Applications A metabolite of Famciclovir, an antiviral.<br>References Harnden, M.R., et al.: J. Med. Chem., 32, 1738 (1989)<br></p>Fórmula:C10H15N5O2Cor e Forma:Off White SolidPeso molecular:237.261R-Dapagliflozin
CAS:Produto Controlado<p>Applications 1R-Dapagliflozin is an isomer of Dapagliflozin (D185370), which is a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Fórmula:C21H25ClO6Cor e Forma:NeatPeso molecular:408.883'-Deoxyinosine
CAS:Produto Controlado<p>Impurity Didanosine EP Impurity D<br>Applications 3'-Deoxyinosine (Didanosine EP Impurity D) is an Inosine (I661000) analog with potential use as an antileishmanial drug. Used as an inhibiting agent in studies of Trypanosoma cruzi growth inside host cells in vitro. An impurity of the antiviral drug 2’,3’-Dideoxyinosine (D440950).<br>References Morishige, K. et al.: Exp. Parasitol., 80, 665 (1995); Aoki, T. et al.: Adv. Exp. Med. Biol., 370, 499 (1994);<br></p>Fórmula:C10H12N4O4Cor e Forma:NeatPeso molecular:252.23α-Decitabine
CAS:Produto Controlado<p>Applications α-Decitabine is shown to inhibit DNA methylation resulting in an effective anticancer agent.<br>References Hajek, M. et al.: Biochem. Pharm., 75, 965 (2008); Rogstad, D. et al.: Chem. Res. Toxicol., 22, 1194 (2009);<br></p>Fórmula:C8H12N4O4Cor e Forma:NeatPeso molecular:228.212,4-Diamino-6-hydroxypyrimidine
CAS:Produto Controlado<p>Applications 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.<br></p>Fórmula:C4H6N4OCor e Forma:NeatPeso molecular:126.12Abacavir-d4
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications Abacavir-d4 is deuterium labeled Abacavir (A104990). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Fórmula:C14H14D4N6OCor e Forma:Off-WhitePeso molecular:290.361’-epi-Cladribine
CAS:<p>Applications 1’-epi-Cladribine is an impurity of Cladribine (C557500), a substituted purine nucleoside with antileukemic activity.<br>References Seto, S., et al.: J. Clin. Invest., 75, 377 (1985), Piro, L.D., et al.: N. Engl. J. Med., 322, 1117 (1990),<br></p>Fórmula:C10H12ClN5O3Cor e Forma:NeatPeso molecular:285.69Floxuridine-13C,15N2
CAS:Produto Controlado<p>Applications Labelled Floxuridine. Antiviral; antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harris, M., et al.: Biophys. J., 4, 203 (1964),<br></p>Fórmula:C813CH11F15N2O5Cor e Forma:WhitePeso molecular:249.17Melamine-15N3
CAS:<p>Applications Isotope labelled Melamine (M208703), which forms synthetic resins with formaldehyde. It remains largely non-metabolized in male Wistar rats with 90% of the administered dose excreted in the urine (1,2) and thus acts as a non-protein nitrogen food additive found in milk (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Mast, R. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Smith, J. et al.: Toxicol Appl Pharmacol. 1994 Apr;125(2):296-308.3. Anirudhan, T. et al.: Food Chem. 2017 Jul 15;227:85-92.<br></p>Fórmula:C3H615N3N3Cor e Forma:White To Off-WhitePeso molecular:129.10Dapagliflozin hydroxy Impurity (Mixture of Diastereomers)
CAS:<p>Applications (1S)-1,5-anhydro-1-C-[4-Chloro-3-[(4-ethoxyphenyl)hydroxymethyl]phenyl]-D-glucitol is an impurity of the drug Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Fórmula:C21H25ClO7Cor e Forma:White To Off-WhitePeso molecular:424.872Zanamivir
CAS:Produto Controlado<p>Applications Influenza viral neuraminidase inhibitor; structural analog of the sialic acid. Antiviral.<br>References Woods, J.M., et al.: Antimicrob. Agents Chemother., 37, 1473 (1993), Pegg, M.S., et al.: Biochem. Mol. Biol. Int., 32, 851 (1994), Monto, A.S., et al.: J. Am. Med. Assoc., 282, 31 (1999),<br></p>Fórmula:C12H20N4O7Cor e Forma:NeatPeso molecular:332.31Adenosine-3’,5’-cyclic Monophosphate
CAS:<p>Stability Hygroscopic<br>Applications Adenosine-3’,5’-cyclic Monophosphate is an Adenosine (A280400) derivative useful as anticancer agent.<br>References Keast, R., et al.: Pharma. Res., 19, 1019 (2002),<br></p>Fórmula:C10H12N5O6PCor e Forma:NeatPeso molecular:329.21[1',2',3',4',5'-13C5]Uridine
CAS:Produto Controlado<p>Applications Labelled Uridine, a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA)<br>References Lorine, P., et al.: J. Biol. Chem., 178, 439 (1949); Grakoui, A., et al.: J. Virol., 63, 5216 (1989); Strauss, J., et al.: Microbiol. Rev., 58, 491 (1994); Lin, Y., et al.: Virology, 292, 78 (2002);<br></p>Fórmula:C5C4H12N2O6Cor e Forma:NeatPeso molecular:249.16Etravirine
CAS:Produto Controlado<p>Applications Etravirine is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection.<br>References Scholler-Gyure, M., et al.: J. Clin. Pharmacol., 48, 322 (2008), Thakur, A., et al.: Eur. J. Med. Chem., 43, 471 (2008),<br></p>Fórmula:C20H15BrN6OCor e Forma:White To Off-WhitePeso molecular:435.28Baquiloprim
CAS:<p>Stability Hygroscopic<br>Applications Baquiloprim is an amiopyrimidine antibacterial synergist with high activity and slow elimination. Baquiloprim has a better half-life than trimethoprim.<br>References Zhi-hui, H., et al.: Anhui Nongye Kexue, 41, 2503 (2013)<br></p>Fórmula:C17H20N6Cor e Forma:Light YellowPeso molecular:308.382’-Deoxycytidine 5'-Monophosphate Hydrate
CAS:Produto Controlado<p>Applications A phosphorylated metabolite of the deoxyribonucleoside 2’-Deoxycytidine. A constituent of Deoxyribonucleic acid. Studies show that it increases influenza virus antigen-induced immune cell proliferation.<br>References Holen, E. et al.: Nutrition, 21, 1003 (2005); Alexandre, J.A. et al.: Nucleosides Nucleotides Nucelic Acids, 26, 1375 (2007);<br></p>Fórmula:C9H14N3O7P·xH2OCor e Forma:White To Off-WhitePeso molecular:307.20 + x(18.02)Gemcitabine-13C,15N2 Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Labelled Gemcitabine, an antineoplastic.<br>References Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990), Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1991), Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1993),<br></p>Fórmula:C813CH12ClF2N15N2O4Cor e Forma:Off-WhitePeso molecular:302.64D-Glucono-1,5-lactone
CAS:Produto Controlado<p>Applications A lactone (cyclic ester) of D-gluconic acid used as a used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent.<br>References Jacob, M. et al.: Food Hydrocoll., 25, 928 (2011); Li, J. et al.: J. Sci. Food Agric., 91, 38, 2011;<br></p>Fórmula:C6H10O6Cor e Forma:NeatPeso molecular:178.142’,2’-Difluoro-2’-deoxyuridine
CAS:Produto ControladoFórmula:C9H10F2N2O5Cor e Forma:White To Off-WhitePeso molecular:264.184-[(2-Chloroethyl)amino]-L-phenylalanine Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-[(2-Chloroethyl)amino]-L-phenylalanine is a metabolite of Melphalan (M216900); an antineoplastic.<br>References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966); Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980)<br></p>Fórmula:C11H15ClN2O2HClCor e Forma:NeatPeso molecular:242.702Dapagliflozin Tetraacetate
CAS:<p>Applications Dapagliflozin Tetraacetate is a derivative of Dapagliflozin [D226255], a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Bernhardson, D. et al.: Org. Proc. Res. Dev., 18, 57 (2014);<br></p>Fórmula:C29H33ClO10Cor e Forma:WhitePeso molecular:577.02ent-Entecavir
CAS:Produto Controlado<p>Applications ent-Entecavir is an enantiomeric impurity of the antiviral drug Entecavir (E558900).<br>References Ruediger, E. et al.: Tetrahed. Lett., 45, 739 (2004): Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);<br></p>Fórmula:C12H15N5O3Cor e Forma:NeatPeso molecular:277.28N-Carbamoyl-2-fluoro-(β)-alanine
CAS:Produto Controlado<p>Applications A metabolite of Capecitabine.<br>References Arellano, M., ET AL.: Br. J. Cancer, 77, 79 (1998), Budman, D., ET AL.: J. Clin. Oncol., 16, 1795 (1998), Khanna, R., et al.: Cancer Res., 60, 4725 (2000), Charasson, V., et al.: Drug Metab. Dispos., 30, 731 (2002),<br></p>Fórmula:C4H7FN2O3Cor e Forma:NeatPeso molecular:150.11Viaminate
CAS:Produto Controlado<p>Applications Viaminate is a pharmaceutical used to treat severe acne and other keratinization disorders. Viaminate can be taken orally, or topically in prepared gels and creams.<br>References Zhang, H.; et al.: Am. J. Med. Sci., 356, 84 (2018); Lu, J.; et al.: Zhongguo Yaofang, 22, 155 (2011); Li, G.: Zhonghua Yiyao Zazhi, 7, 536 (2007).<br></p>Fórmula:C29H37NO3Cor e Forma:Light YellowPeso molecular:447.61Canagliflozin 2-Glucuronide
CAS:Produto Controlado<p>Applications Canagliflozin 2-glucuronide is a derivative of Canagliflozin (C175190). Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that is used to treat patients with type 2 diabetes. Canagliflozin lowers blood glucose by increasing the amount of glucose that exits the body through urinary excretion.<br>References Devineni, D., et al.: Diab. Obes. Metab., 14, 539 (2012); Nicolle, L., et al.: Curr. Med. Res. Opin., 28, 1167 (2012)<br></p>Fórmula:C30H33FO11SCor e Forma:NeatPeso molecular:620.64
![cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FF591850.webp&w=3840&q=75)
![[1',2',3',4',5'-13C5]Uridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FU829917.webp&w=3840&q=75)
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