Nucleosídeos e Nucleotídeos
Os nucleosídeos são compostos formados por uma base nitrogenada ligada a um açúcar (ribose ou desoxirribose). Quando um grupo fosfato é adicionado ao nucleosídeo, forma-se um nucleotídeo. Esses compostos são essenciais na biologia celular, pois os nucleotídeos são os blocos fundamentais do DNA e RNA, responsáveis pelo armazenamento e transmissão da informação genética. Os nucleosídeos têm aplicações no tratamento de doenças virais, atuando como inibidores da replicação viral. Os nucleotídeos, além do seu papel estrutural nos ácidos nucleicos, participam de processos energéticos, como a síntese de ATP.
Na CymitQuimica, oferecemos uma ampla gama de nucleosídeos e nucleotídeos essenciais para pesquisa em biologia molecular, virologia e farmacologia.
Foram encontrados 3427 produtos de "Nucleosídeos e Nucleotídeos"
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1-(Diaminomethylene)-3-b-D-ribofuranosyl-urea Picrate
CAS:Produto Controlado<p>Impurity Azacitidine USP Related Compound C<br>Stability Hygroscopic<br>Applications 1-(Diaminomethylene)-3-β-D-ribofuranosyl-urea Picrate is a related compound of Azacitidine, a DNA metnyltransferase (DNMT) inhibitor for treating myelodysplastic syndromes (MDS).<br>References Rajendiran, C., et al.: PCT Int. Appl. WO 2012135405 A1 20121004 (2012); Ziemba, A., et al.: Chemother Res Pract 965826, 9 (2011); Beisler, J. A., et al.: J. Carbohyd. Chem 4, 281 (1977)<br></p>Fórmula:C7H14N4O5·C6H3N3O7Cor e Forma:YellowPeso molecular:463.313'-Azido-3'-deoxy-5'-O-tritylthymidine
CAS:Produto ControladoFórmula:C29H27N5O4Cor e Forma:NeatPeso molecular:509.56Lamivudine Triphosphate Triethylamine Salt (90%)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Lamivudine (L172500).<br>References Burgess, K., et al.: Chem. Rev., 100, 2047 (2000), Gallois-Montbrun, S., et al.: Biochem. Pharmacol., 68, 1749 (2004),<br></p>Fórmula:C8H14N3O12P3SC6H15NxPureza:90%Cor e Forma:NeatPeso molecular:469.20101195-Chloro-1-methyl-4-nitroimidazole
CAS:Produto Controlado<p>Impurity Azathioprine EP Impurity C<br>Applications 5-Chloro-1-methyl-4-nitroimidazole (cas# 4897-25-0) is a compound useful in organic synthesis.<br></p>Fórmula:C4H4ClN3O2Cor e Forma:White To Off-WhitePeso molecular:161.55(-)-Inosine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Has neuroprotective properties improving axonal wiring. Has been used to treat stroke patients to restore neural function. Neuroprotective product.<br>References Vandemeulebroucke, A., et al.: Biochem., 49, 8999 (2010), Nestor, G., et al.: J. Agric. Food Chem., 58, 10799 (2010),<br></p>Fórmula:C10H12N4O5Cor e Forma:White To Off-WhitePeso molecular:268.23Guanine
CAS:<p>Impurity Aciclovir EP Impurity B<br>Applications Guanine is one of the five nucleobases incorporated into biological nucleic acids. Guanine, along with adenine and cytosine, is present in both DNA and RNA, whereas thymine is usually seen only in DNA, and uracil only in RNA. Aciclovir EP Impurity B.<br>References Geslain, R., et al.: J. Biol. Chem., 284, 27760 (2009); Manini, P., et al.: Toxicol. Lett., 190, 41 (2009); Gong, B., et al.: Biochem., 48, 11961 (2009); Sugimoto, M., et al.: J. Agric. Food Chem., 58, 374 (2010);<br></p>Fórmula:C5H5N5OCor e Forma:White To Off-WhitePeso molecular:151.13Cytidine 5'-Diphosphocholine
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications Cytidine 5'-diphosphocholine (cas# 987-78-0) is a useful research chemical.<br></p>Fórmula:C14H26N4O11P2Cor e Forma:Off-WhitePeso molecular:488.32Emtricitabine-13C,15N2
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications Labelled Emtricitabine. A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).<br>References Schinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. Infec. Dis., 182, 599 (2000)<br></p>Fórmula:CC7H10F15N2NO3SCor e Forma:White To Light YellowPeso molecular:250.234-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone
CAS:<p>Applications 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone is an impurity of Capecitabine (C175650), which is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).<br>References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Fórmula:C13H16FN3O6Cor e Forma:Off White PowderPeso molecular:329.28Melamine (1 mg/10 mL in 84:16% ACN:H2O)
CAS:Produto ControladoFórmula:C3H6N6Cor e Forma:Single SolutionPeso molecular:126.122-Amino-6-(chloromethyl)-4(3H)-pteridinone (>90%)
CAS:Produto Controlado<p>Applications 2-Amino-6-(chloromethyl)-4(3H)-pteridinone is a reagent/intermediate used in the preparation of Folic Acid (F680300) and its derivatives.<br>References Qi, Y., et al.: Faming Zhuanli Shenqing. CN 103755706 A 20140430. Apr 30, 2014;<br></p>Fórmula:C7H6ClN5OPureza:>90%Cor e Forma:NeatPeso molecular:211.61Biopterin-d3
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled Biopterin. A pteridine widely distributed in nature; naturally occurring as the L-erythro-form. Considered as a growth factor for some insects. Fluoresces with a blue color in alkaline solution.<br>References Klatt, P., et al.: J. Biol. Chem., 269, 13861 (1994), Mitnaul, L., et al.: Biochemistry, 92, 885 (1995), Thony, B., et al.: Biochem. J., 347, 1 (2000),<br></p>Fórmula:C92H3H8N5O3Cor e Forma:Beige To BrownPeso molecular:240.236-Benzylaminopurine 9-(β-D-glucoside)
CAS:<p>Applications 6-Benzylaminopurine 9-(β-D-glucoside) (cas# 4294-17-1) is a compound useful in organic synthesis.<br></p>Fórmula:C18H21N5O5Cor e Forma:NeatPeso molecular:387.39O-[(Guanin-9-yl)methyl] Acyclovir
CAS:<p>Impurity Aciclovir EP Impurity J<br>Applications O-(Guanin-9-yl)methyl Acyclovir (Aciclovir EP Impurity J) is a dimer impurity of the antiviral agent Acyclovir (A192400).<br>References Ashton, D.S. et al.: J. Chrom. A, 707, 367 (1995);<br></p>Fórmula:C14H16N10O4Cor e Forma:BeigePeso molecular:388.34Iso Ribavirin (Ribavirin Impurity G)
CAS:Produto ControladoFórmula:C8H12N4O5Cor e Forma:NeatPeso molecular:244.2Phosphoric Acid Dibenzyl Ester
CAS:<p>Stability Moisture Sensitive<br>Applications Eye irritant.<br>References Bagley, D. M. et al.; Toxicol. In Vitro 13, 505 (1999); Gilleron, L. et al.; Toxicol. In Vitro 11, 641 (1997)<br></p>Fórmula:C14H15O4PCor e Forma:NeatPeso molecular:278.24Adenine
CAS:Produto Controlado<p>Applications Widespread throughout animal and plant tissues combined with niacinamide, d-ribose, and phosphoric acids; a constituent of nucleic acids and coenzymes, such as codehydrase I and II, adenylic acid, coalaninedehydrase. It is used in microbial determination of niacin; in research on heredity, virus diseases, and cancer.<br>References Philips, et al.: J. Pharmacol. Exp. Ther., 20, 104 (1952), Lambertucci, C., et al.: Bioorg. Med. Chem., 17, 2812 (2009),<br></p>Fórmula:C5H5N5Cor e Forma:Light YellowPeso molecular:135.135-Fluorodihydropyrimidine-2,4-dione
CAS:Produto Controlado<p>Applications A metabolite of 5-Fluorouracil. (F596000)<br>References Bocci, G., et al.: Eur. J. Clin. Pharmacol., 58, 593 (2002), Longley, D.B., Nature Rev. Cancer, 3, 330 (2003), Fischel, J., et al.: Anti-Cancer Drugs, 15, 969 (2004)<br></p>Fórmula:C4H5FN2O2Cor e Forma:NeatPeso molecular:132.093Levomefolic Acid
CAS:<p>Applications A natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. It is a coenzymated form of folic acid. It has been proposed for treatment of cardiovascular disease.<br>References Willems, F. et al.: Br. J. Pharmacol., 145, 823 (2004); Prinz-Langhebohi, R.: et al., Br. J. Pharmacol., 158, 2014 (2009); Wright, A. et al.: Brit, J. Nutrit., 103, 724 (2010)<br></p>Fórmula:C20H25N7O6Cor e Forma:NeatPeso molecular:459.46Melphalan-d8 Monohydrochloride
CAS:Produto ControladoFórmula:C13H10D8Cl2N2O2·HClCor e Forma:WhitePeso molecular:349.71N-Methyltetrahydrofolic Acid
CAS:Produto Controlado<p>Applications N-Methyltetrahydrofolic acid (cas# 134-35-0) is a useful research chemical.<br></p>Fórmula:C20H25N7O6Cor e Forma:NeatPeso molecular:459.46Cytarabine-13C3
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled Cytarabine, a compound used as an antineoplastic and antiviral. A selective inhibitor of DNA synthesis. Does not inhibit RNA synthesis.<br>References Donehower, R.C., et al.: Cancer Treat. Rep., 70, 1059 (1986)<br></p>Fórmula:C613C3H13N3O5Cor e Forma:BeigePeso molecular:246.191-β-D-Arabinofuranosyluracil
CAS:<p>Impurity Cytarabine EP Impurity A<br>Applications Antiviral agent. Used for the treatment of severe acute respiratory syndrome (SARS).<br>References Weber, G., et al.: Cancer Res., 43, 3466 (1983), Broet, P., et al.: J. Clin. Oncol., 19, 2778 (2001), Galmarini, C., et al.: Leukemia, 15, 875 (2001), Barth, R., et al.: Cancer Res., 64, 6287 (2004), Song, M., et al.: Bioorg. Med. Chem., 12, 489 (2004),<br></p>Fórmula:C9H12N2O6Cor e Forma:WhitePeso molecular:244.20Thymidine
CAS:Produto Controlado<p>Applications Constituent of deoxyribonucleic acid.<br>References Levene, L., et al.: J. Bil. Chem. 83, 793 (1929), Tollin, et al.: Nature 217, 1148 (1968), Redzic, Z., et al.: Neurochem. Res., 34, 566 (2009), Hazra, S., et al.: Biochem., 48, 1256 (2009), Yang, I., et al.: J. Biol. Chem., 284, 191 (2009),<br></p>Fórmula:C10H14N2O5Cor e Forma:White To Off-WhitePeso molecular:242.23Adenosine 5'-monophosphate monohydrate
CAS:Produto ControladoFórmula:C10H14N5O7P·H2OCor e Forma:NeatPeso molecular:365.2310-Formyl Folic Acid-d4
CAS:Produto Controlado<p>Stability Air Sensitive<br>Applications A labelled Folic acid (F680300) derivative (or folate) found in daily dietary intake that is often used in cancer risk correlation studies.<br>References Keszei, A.P. et al.: Cancer Epidimiol. Biomarker Prev., 18, 1785 (2009); Koning, E.J. et al.: Cancer, 95, 1421 (2002);<br></p>Fórmula:C20H15D4N7O7Cor e Forma:NeatPeso molecular:473.43Zanamivir-13C,15N2
CAS:Produto Controlado<p>Applications Influenza viral neuraminidase inhibitor; structural analog of the sialic acid. Antiviral.<br>References Woods, J.M., et al.: Antimicrob. Agents Chemother., 37, 1473 (1993), Pegg, M.S., et al.: Biochem. Mol. Biol. Int., 32, 851 (1994), Monto, A.S., et al.: J. Am. Med. Assoc., 282, 31 (1999),<br></p>Fórmula:CC11H2015N2N2O7Cor e Forma:NeatPeso molecular:335.294-Desethoxy-2-ethoxy Dapagliflozin, >90%
CAS:Produto Controlado<p>Applications (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(2-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol is an impurity of Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Fórmula:C21H25ClO6Pureza:>90%Cor e Forma:NeatPeso molecular:408.875’-Deoxy-5-fluorocytidine-13C,15N2
CAS:Produto Controlado<p>Applications A labelled metabolite of Capecitabine.<br></p>Fórmula:C813CH12FN15N2O4Cor e Forma:NeatPeso molecular:248.19Abacavir 5’-β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Abacavir 5’-β-D-Glucuronide is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Fórmula:C20H25N6NaO7Cor e Forma:NeatPeso molecular:484.44Fenretinide
CAS:Produto Controlado<p>Stability Light Sensitive - Protect from Light Exposure<br>Applications Fenretinide (4-HPR) is a synthetic retinoid deriverative. 4-HBR is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.A synthetic analog of Vitamin A.<br>References Marth, C., et al.:J. Nat. Cancer Inst., 75, 871 (1985), Delia, D., et al.: Cancer Res., 53, 6036 (1993), Costa., A., et al.: Cancer Res., 54, Suppl., 2032s (1994), Decensi., A., et al.: Eur. J. Cancer Prev., 3, 377 (1994)<br></p>Fórmula:C26H33NO2Cor e Forma:NeatPeso molecular:391.551-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications 1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one is an impurity of 5-Azacytidine (A796000), a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase.<br>References Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999), Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999), Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999), Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)<br></p>Fórmula:C10H14N4O6Cor e Forma:White To Off-WhitePeso molecular:286.24Capecitabine
CAS:Produto Controlado<p>Applications Capecitabine is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).<br>References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Fórmula:C15H22FN3O6Cor e Forma:NeatPeso molecular:359.35N,O-Diacetate Isoacyclovir
CAS:Produto Controlado<p>Impurity Aciclovir EP Impurity M<br>Applications An impurity of Acyclovir. Aciclovir EP Impurity M<br>References Laskin, O., et al.: Clin. Pharmacok., 8, 187 (1983), Grass, G., et al.: Pharm. Res., 5, 372 (1988), Mahony, W., et al.: J. Biol. Chem., 263, 9285 (1988), Merino, V., et al.: J. Pharm. Sci., 84, 777 (1995),<br></p>Fórmula:C12H15N5O5Cor e Forma:NeatPeso molecular:309.2785’-Ethylcarboxamido Adenosine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A potent adenosine receptor agonist. Inhibits platelet aggregation and is centrally active in vivo.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cusack and Hourani: Br. J. Pharmacol., 72, 433 (1981), Knapp, et al.: Pharmacol. Biochem. Behav., 68, 797 (2001)<br></p>Fórmula:C12H16N6O4Cor e Forma:NeatPeso molecular:308.29Cidofovir Diphosphate Trisodium Salt (>85%)
CAS:Produto Controlado<p>Applications Cidofovir Diphosphate Trisodium Salt has antiviral activity, which is used against herpes viruses. Cidofovir Diphosphate is a metabolite in human cells.<br>References Hitchcock, M. J. M., et al.: Antivir. Chem. Chemoth., 7, 115-127 (1996); Cihlar, T., et al.: Collect. Czech. Chem. C., 57, 661-72 (1992)<br></p>Fórmula:C8H13N3Na3O12P3Pureza:>85%Cor e Forma:NeatPeso molecular:505.092Ammeline
CAS:<p>Applications Ammeline is a metabolite of Melamine (1) (M208700), which acts as a non-protein nitrogen food additive (2). Also present in pet foods as well (3).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Mast RW. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Ehling S. et al.: Food Addit Contam. 2007 Dec;24(12):1319-25.3. Vail T. et al.: J Anal Toxicol. 2007 Jul-Aug;31(6):304-12.<br></p>Fórmula:C3H5N5OCor e Forma:ColourlessPeso molecular:127.10Decarboxylated S-Adenosylmethionine Sulfate Salt
CAS:<p>Stability Hygroscopic<br>Applications Decarboxylated S-Adenosylmethionine Sulfate Salt, is a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine.<br>References Takahashi,T., et al.: Ann. Bot., 105, 1 (2009); Wu, H., et al.: Biochem., 46, 8331 (2007); Pegg, A., et al.: Biochem., 28, 8446 (1989);<br></p>Fórmula:C14H23N6O3S•H2SO4•HSO4Cor e Forma:White SolidPeso molecular:355.44980797065-Methyluridine
CAS:<p>Applications A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.<br>References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),<br></p>Fórmula:C10H14N2O6Cor e Forma:NeatPeso molecular:258.23Adenosine 5'-Monophosphate
CAS:Produto Controlado<p>Applications Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.<br>References Hong, J.A. et al.: J. Med. Chem., 52, 5485 (2009); Korboukh I. et al.: J. Med. Chem., 55, 6467 (2012)<br></p>Fórmula:C10H14N5O7PCor e Forma:NeatPeso molecular:347.225-Methyl-2’-deoxy Cytidine
CAS:<p>Applications A Cytidine (C998300) analog and also an isostere of Thymidine (T412000).<br>References Sabini, E., et al.: J. Med. Chem., 51, 4219 (2008), Sabini, E., et al.: J. Mol. Biol., 378, 607 (2008),<br></p>Fórmula:C10H15N3O4Cor e Forma:NeatPeso molecular:241.243’-Amino-3’-deoxythymidine
CAS:Produto Controlado<p>Impurity Zidovudine Impurity;<br>Stability Hygroscopic, Moisture Sensitive<br>Applications A metabolite of Zidovudine (3'-Azido-3'-deoxythymidine; AZT).<br>References Qian, M., et al.: Biochem. Pharmacol., 48, 383 (1994), Diwan, B., et al.: Toxicol. Appl. Pharmacol., 161, 82 (1999) , Lim, S., et al.: J. Biol. Chem., 276, 23616 (2001), Von Tungeln, L., et al.: Carcinogenesis, 23, 1427 (2002),<br></p>Fórmula:C10H15N3O4Cor e Forma:White To Off-WhitePeso molecular:241.24Entecavir-13C2,15N
CAS:Produto Controlado<p>Applications Labelled Entecavir. An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.<br>References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),<br></p>Fórmula:C1013C2H15N415NO3Cor e Forma:White To Off-WhitePeso molecular:280.264’-Epi Lamivudine
CAS:Produto Controlado<p>Applications Lamivudine epimer.<br>References Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992), Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Fórmula:C8H11N3O3SCor e Forma:NeatPeso molecular:229.26N-Des-1-β-D-ribofuranosyl Ribavirin
CAS:<p>Impurity Ribavirin EP Impurity D<br>Applications N-Des-1-β-D-ribofuranosyl Ribavirin (Ribavirin EP Impurity D) is an impurity in the synthesis of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Fórmula:C3H4N4OCor e Forma:Off White SolidPeso molecular:112.09RO 2433
CAS:Produto Controlado<p>Impurity Sofosbuvir Metabolite GS331007<br>Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.<br>References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)<br></p>Fórmula:C10H13FN2O5Cor e Forma:NeatPeso molecular:260.223’,5’-Di-O-benzyl Entecavir
CAS:Produto Controlado<p>Applications 3’,5’-Di-O-benzyl Entecavir is an intermediate in the preparation of the hepatitis B antiviral agent, Entecavir (E558900).<br>References Li, R. et al.: Zhong. Yao., 6, 292 (2008); Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);<br></p>Fórmula:C26H27N5O3Cor e Forma:NeatPeso molecular:457.522'-Deoxy-2',2'-difluorocytidine 5'-monophosphate
CAS:<p>2'-Deoxy-2',2'-difluorocytidine 5'-monophosphate (CDFMP) is a potent antitumor agent that has been shown to have a strong anti-angiogenic effect. It inhibits the cancer cell's production of microvessels and interferes with the formation of new blood vessels from pre-existing ones, which can be used to deliver chemotherapy drugs to the tumor. CDFMP is synthesized by reacting 2'-deoxy-2',2'-difluorocytidine with phosphoric acid and then converting it into the monophosphate form using phosphorus oxychloride. This drug is also resistant to platinum-based chemotherapy agents, making it a promising drug for patients who are resistant to other treatments.</p>Fórmula:C9H12F2N3O7PPureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:343.18 g/molRemdesivir impurity 10
CAS:<p>Remdesivir impurity 10 is a synthetic chemical compound that has been synthesized for research and development. It is an impurity standard of remdesivir, which is not present in any drug product. The purity of this product is high, and it can be used as a pharmacopoeia or drug development standard. It can also be used as an analytical standard to measure the concentration of metabolites in animal studies or metabolism studies.</p>Fórmula:C27H35N6O8PPureza:Min. 95%Peso molecular:602.58 g/mol
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