Nucleosídeos e Nucleotídeos
Os nucleosídeos são compostos formados por uma base nitrogenada ligada a um açúcar (ribose ou desoxirribose). Quando um grupo fosfato é adicionado ao nucleosídeo, forma-se um nucleotídeo. Esses compostos são essenciais na biologia celular, pois os nucleotídeos são os blocos fundamentais do DNA e RNA, responsáveis pelo armazenamento e transmissão da informação genética. Os nucleosídeos têm aplicações no tratamento de doenças virais, atuando como inibidores da replicação viral. Os nucleotídeos, além do seu papel estrutural nos ácidos nucleicos, participam de processos energéticos, como a síntese de ATP.
Na CymitQuimica, oferecemos uma ampla gama de nucleosídeos e nucleotídeos essenciais para pesquisa em biologia molecular, virologia e farmacologia.
Foram encontrados 3421 produtos de "Nucleosídeos e Nucleotídeos"
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2'-Deoxy-2',2'-difluorouridine
CAS:<p>Gemcitabine metabolite</p>Fórmula:C9H10F2N2O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:264.19 g/molS19-1035
<p>S19-1035: potent AKR1C3 inhibitor with 3.04 nM IC50, useful for tumor research.</p>Fórmula:C19H17ClN2O3Pureza:99.98%Cor e Forma:SoildPeso molecular:356.80APX-115
CAS:<p>APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4).</p>Fórmula:C17H18ClN3OPureza:98.62%Cor e Forma:SolidPeso molecular:315.8Methyl 2-deoxy-D-ribopyranoside
CAS:<p>Methyl 2-deoxy-D-ribopyranoside (2DDR) is a natural compound that can be found as an impurity in some pharmaceuticals. The chemical structure of 2DDR is similar to 6-fluoro-3-indoxyl beta-D-galactopyranoside, which is used to treat tuberculosis. The metabolism of 2DDR has been studied, and it has been found that this metabolite is excreted in the urine unchanged or conjugated with glucuronic acid. This product can be used for drug development and research and development. It can also be used as an impurity standard for HPLC analysis or as a custom synthesis for niche applications.</p>Fórmula:C6H12O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:148.16 g/molDapagliflozin Impurity 26
CAS:<p>Dapagliflozin Impurity 26 is an impurity that is found in the chemical analysis of Dapagliflozin. It is a metabolite, which is not present in the drug product and does not have any biological activity. Dapagliflozin Impurity 26 has been shown to be a high purity, analytical standard for HPLC and can be used as an API impurity for drug development. This compound can also be synthesized by natural or synthetic means.</p>Pureza:Min. 95%N6-(2-Phenylethyl)adenosine
CAS:<p>N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for</p>Fórmula:C18H21N5O4Pureza:99.83%Cor e Forma:SolidPeso molecular:371.39Meropenem EP impurity A
CAS:<p>Meropenem EP impurity A is a heterocyclic nitro compound that is used to treat various infectious diseases. Meropenem EP impurity A is an inhibitor of the toll-like receptor, which is a protein that recognizes and binds to bacterial lipopolysaccharide and mediates inflammation. This drug may be effective in treating colorectal carcinoma, autoimmune diseases, chronic bronchitis, cancer, and other inflammatory diseases. Meropenem EP impurity A also has anti-cancer properties due to its structural similarity with the chemotherapeutic agent 5-fluorouracil. Meropenem EP impurity A inhibits the synthesis of proteins by binding to the aminoacyl-tRNA synthetase enzyme and blocking the production of proteins vital for cell division.</p>Fórmula:C17H27N3OS6Pureza:95%NmrCor e Forma:PowderPeso molecular:401.5 g/mol6-Pterinyl folic acid
CAS:<p>6-Pterinyl folic acid is a chemical reagent that is used in the synthesis of pteridine derivatives. It is also used to prepare sulfates and esters of folic acid. 6-Pterinyl folic acid can be synthesized by reacting glutamic anhydride with trifluoroacetic acid and dimethylformamide. It reacts with sulfate ions to produce 6-pterinyl sulfate, which can then be hydrolyzed to release 6-pterinyl folic acid. The reagent can be used in the manufacture of fluoroquinolones, antibiotics that are used to treat a variety of bacterial infections including tuberculosis.</p>Fórmula:C26H24N12O7Pureza:Min. 95%Peso molecular:616.55 g/molPSI 7976
CAS:<p>PSI 7976 is an analog of the nucleophilic attack drug, ribavirin. PSI 7976 inhibits the hepatitis C virus (HCV) replicon by inhibiting the function of the NS5B polymerase. In clinical studies, PSI 7976 has been shown to be active against HCV genotype 1 and 3. It has also been shown to inhibit replication of HIV-1 in vitro and to act synergistically with lamivudine against HIV-1 in human cells. PSI 7976 may be useful as a potential antiviral agent for treatment of other viral infections such as hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), or cytomegalovirus (CMV).</p>Fórmula:C22H29FN3O9PPureza:Min. 95%Peso molecular:529.45 g/molMolnupiravir
CAS:<p>Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.Cost-effective and quality-assured.</p>Fórmula:C13H19N3O7Pureza:99.81% - 99.98%Cor e Forma:SolidPeso molecular:329.31HTS07545
CAS:<p>HTS07545, an SQOR inhibitor (IC50: 30nM), slows H2S breakdown, researched for heart failure.</p>Fórmula:C22H18N2O3Pureza:99.71%Cor e Forma:SolidPeso molecular:358.39Phox-I2
CAS:<p>Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.</p>Fórmula:C18H15N3O4Pureza:99.73%Cor e Forma:SolidPeso molecular:337.33Emtricitabine impurity 17
CAS:<p>Please enquire for more information about Emtricitabine impurity 17 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C8H10FN3O4SPureza:Min. 95%Peso molecular:263.24 g/molML-090
CAS:<p>ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).</p>Fórmula:C14H10N4Pureza:98.55%Cor e Forma:SolidPeso molecular:234.26Carbovir
CAS:<p>Carbovir, an NRTI, induces mitochondrial toxicity in human liver cancer cells.</p>Fórmula:C11H13N5O2Cor e Forma:SolidPeso molecular:247.25AMPA receptor modulator-2
CAS:<p>AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.</p>Fórmula:C15H6F6N4OSPureza:99.8%Cor e Forma:SolidPeso molecular:404.29Zidovudine diphosphate
CAS:<p>Zidovudine diphosphate, an NRTI antiretroviral, treats HIV/AIDS by blocking reverse transcriptase, preventing viral DNA synthesis.</p>Fórmula:C10H15N5O10P2Cor e Forma:SolidPeso molecular:427.2Ganciclovir triphosphate
CAS:<p>Ganciclovir triphosphate: synthetic 2'-deoxy-guanosine analog, treats/prevents CMV, IC50 of 0.01 μM, effective across species.</p>Fórmula:C9H16N5O13P3Cor e Forma:SolidPeso molecular:495.17Galidesivir dihydrochloride
CAS:<p>Galidesivir inhibits RdRP; has broad antiviral effects on various RNA viruses; effective against Ebola, Marburg in animals.</p>Fórmula:C11H17Cl2N5O3Cor e Forma:SolidPeso molecular:338.19ES 936
CAS:<p>ES 936 is a potent and selective NQO1 inhibitor, inhibiting more than 95% of NQO1 100 nM, with a cell line-dependent inhibition duration.</p>Fórmula:C18H16N2O6Pureza:98%Cor e Forma:SolidPeso molecular:356.33Brivudine monophosphate
CAS:<p>Brivudine monophosphate, a phosphate ester, inhibits DNA repair, induces apoptosis, and may downregulate STAT3 and chemoresistance genes.</p>Fórmula:C11H14BrN2O8PCor e Forma:SolidPeso molecular:413.12GLX481304
CAS:<p>GLX481304 is a selective Nox-2 and Nox-4 inhibitor, exhibiting IC50 values of 1.25 μM.</p>Fórmula:C23H29N7OCor e Forma:SolidPeso molecular:419.52NOX2-IN-2
CAS:<p>NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM.</p>Fórmula:C25H25N7O3Cor e Forma:SolidPeso molecular:471.51Emtricitabine triphosphate tetrasodium salt
CAS:<p>Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleoside</p>Fórmula:C8H9FN3Na4O12P3SPureza:98%Cor e Forma:SolidPeso molecular:575.11Sorivudine
CAS:<p>Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.</p>Fórmula:C11H13BrN2O6Pureza:99.74%Cor e Forma:SolidPeso molecular:349.13GS 441524 triphosphate
CAS:<p>Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.</p>Fórmula:C12H12N5O13P3·4NaPureza:(31P-Nmr) Min. 95 Area-%Cor e Forma:White PowderPeso molecular:531.20 g/molEmtricitabine triphosphate
CAS:<p>Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.</p>Fórmula:C8H13FN3O12P3SCor e Forma:SolidPeso molecular:487.19Galidesivir
CAS:<p>Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.</p>Fórmula:C11H15N5O3Pureza:96.73% - 99.13%Cor e Forma:SolidPeso molecular:265.27Lobucavir
CAS:<p>Lobucavir (BMS-180194; SQ 34514) is a nucleoside analogue and an antiviral agent with broad-spectrum activity against various viruses, including HBV, HIV/AIDS, and α, β, and γ herpesviruses (including CMV, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus).</p>Fórmula:C11H15N5O3Cor e Forma:SolidPeso molecular:265.27Ref: 4Z-A-267065
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