Nucleosídeos e Nucleotídeos
Os nucleosídeos são compostos formados por uma base nitrogenada ligada a um açúcar (ribose ou desoxirribose). Quando um grupo fosfato é adicionado ao nucleosídeo, forma-se um nucleotídeo. Esses compostos são essenciais na biologia celular, pois os nucleotídeos são os blocos fundamentais do DNA e RNA, responsáveis pelo armazenamento e transmissão da informação genética. Os nucleosídeos têm aplicações no tratamento de doenças virais, atuando como inibidores da replicação viral. Os nucleotídeos, além do seu papel estrutural nos ácidos nucleicos, participam de processos energéticos, como a síntese de ATP.
Na CymitQuimica, oferecemos uma ampla gama de nucleosídeos e nucleotídeos essenciais para pesquisa em biologia molecular, virologia e farmacologia.
Foram encontrados 3458 produtos de "Nucleosídeos e Nucleotídeos"
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Methyl 2-deoxy-D-ribopyranoside
CAS:Methyl 2-deoxy-D-ribopyranoside (2DDR) is a natural compound that can be found as an impurity in some pharmaceuticals. The chemical structure of 2DDR is similar to 6-fluoro-3-indoxyl beta-D-galactopyranoside, which is used to treat tuberculosis. The metabolism of 2DDR has been studied, and it has been found that this metabolite is excreted in the urine unchanged or conjugated with glucuronic acid. This product can be used for drug development and research and development. It can also be used as an impurity standard for HPLC analysis or as a custom synthesis for niche applications.Fórmula:C6H12O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:148.16 g/molAPX-115
CAS:APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4).Fórmula:C17H18ClN3OPureza:98.62%Cor e Forma:SolidPeso molecular:315.8Ref: TM-T10354
1mg34,00€5mg75,00€10mg110,00€25mg222,00€50mg334,00€100mg475,00€500mg964,00€1mL*10mM (DMSO)92,00€Dapagliflozin Impurity 26
CAS:Dapagliflozin Impurity 26 is an impurity that is found in the chemical analysis of Dapagliflozin. It is a metabolite, which is not present in the drug product and does not have any biological activity. Dapagliflozin Impurity 26 has been shown to be a high purity, analytical standard for HPLC and can be used as an API impurity for drug development. This compound can also be synthesized by natural or synthetic means.Pureza:Min. 95%N6-(2-Phenylethyl)adenosine
CAS:N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM forFórmula:C18H21N5O4Pureza:99.83%Cor e Forma:SolidPeso molecular:371.39Phox-I2
CAS:Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.
Fórmula:C18H15N3O4Pureza:99.73%Cor e Forma:SolidPeso molecular:337.33Peldesine
CAS:Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.Fórmula:C12H11N5OPureza:99.27% - 99.9%Cor e Forma:SolidPeso molecular:241.25Ref: TM-T12399
1mg108,00€5mg260,00€10mg416,00€25mg690,00€50mg964,00€100mg1.305,00€500mg2.592,00€1mL*10mM (DMSO)286,00€PSI 7976
CAS:PSI 7976 is an analog of the nucleophilic attack drug, ribavirin. PSI 7976 inhibits the hepatitis C virus (HCV) replicon by inhibiting the function of the NS5B polymerase. In clinical studies, PSI 7976 has been shown to be active against HCV genotype 1 and 3. It has also been shown to inhibit replication of HIV-1 in vitro and to act synergistically with lamivudine against HIV-1 in human cells. PSI 7976 may be useful as a potential antiviral agent for treatment of other viral infections such as hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), or cytomegalovirus (CMV).Fórmula:C22H29FN3O9PPureza:Min. 95%Peso molecular:529.45 g/molMolnupiravir
CAS:Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.Cost-effective and quality-assured.Fórmula:C13H19N3O7Pureza:99.81% - 99.98%Cor e Forma:SolidPeso molecular:329.31Ref: TM-T60951
1g973,00€5mg38,00€10mg57,00€25mg74,00€50mg113,00€100mg177,00€200mg334,00€500mg710,00€1mL*10mM (DMSO)63,00€6-Pterinyl folic acid
CAS:6-Pterinyl folic acid is a chemical reagent that is used in the synthesis of pteridine derivatives. It is also used to prepare sulfates and esters of folic acid. 6-Pterinyl folic acid can be synthesized by reacting glutamic anhydride with trifluoroacetic acid and dimethylformamide. It reacts with sulfate ions to produce 6-pterinyl sulfate, which can then be hydrolyzed to release 6-pterinyl folic acid. The reagent can be used in the manufacture of fluoroquinolones, antibiotics that are used to treat a variety of bacterial infections including tuberculosis.Fórmula:C26H24N12O7Pureza:Min. 95%Peso molecular:616.55 g/molS19-1035
S19-1035: potent AKR1C3 inhibitor with 3.04 nM IC50, useful for tumor research.
Fórmula:C19H17ClN2O3Pureza:99.98%Cor e Forma:SoildPeso molecular:356.80Meropenem EP impurity A
CAS:Meropenem EP impurity A is a heterocyclic nitro compound that is used to treat various infectious diseases. Meropenem EP impurity A is an inhibitor of the toll-like receptor, which is a protein that recognizes and binds to bacterial lipopolysaccharide and mediates inflammation. This drug may be effective in treating colorectal carcinoma, autoimmune diseases, chronic bronchitis, cancer, and other inflammatory diseases. Meropenem EP impurity A also has anti-cancer properties due to its structural similarity with the chemotherapeutic agent 5-fluorouracil. Meropenem EP impurity A inhibits the synthesis of proteins by binding to the aminoacyl-tRNA synthetase enzyme and blocking the production of proteins vital for cell division.Fórmula:C17H27N3OS6Pureza:95%NmrCor e Forma:PowderPeso molecular:401.5 g/molHTS07545
CAS:HTS07545, an SQOR inhibitor (IC50: 30nM), slows H2S breakdown, researched for heart failure.
Fórmula:C22H18N2O3Pureza:99.71%Cor e Forma:SolidPeso molecular:358.392'-Deoxy-2',2'-difluorouridine
CAS:Gemcitabine metaboliteFórmula:C9H10F2N2O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:264.19 g/molNOX2-IN-2
CAS:NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM.Fórmula:C25H25N7O3Cor e Forma:SolidPeso molecular:471.51Carbovir
CAS:Carbovir, an NRTI, induces mitochondrial toxicity in human liver cancer cells.Fórmula:C11H13N5O2Cor e Forma:SolidPeso molecular:247.25AMPA receptor modulator-2
CAS:AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.
Fórmula:C15H6F6N4OSPureza:99.8%Cor e Forma:SolidPeso molecular:404.29GLX481304
CAS:GLX481304 is a selective Nox-2 and Nox-4 inhibitor, exhibiting IC50 values of 1.25 μM.Fórmula:C23H29N7OCor e Forma:SolidPeso molecular:419.52Brivudine monophosphate
CAS:Brivudine monophosphate, a phosphate ester, inhibits DNA repair, induces apoptosis, and may downregulate STAT3 and chemoresistance genes.Fórmula:C11H14BrN2O8PCor e Forma:SolidPeso molecular:413.12ML-090
CAS:ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).Fórmula:C14H10N4Pureza:98.55%Cor e Forma:SolidPeso molecular:234.26Emtricitabine triphosphate tetrasodium salt
CAS:Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleosideFórmula:C8H9FN3Na4O12P3SPureza:98%Cor e Forma:SolidPeso molecular:575.11
