Sais e Derivados de API
Os sais dos Ingredientes Farmacêuticos Ativos (API) são compostos formados pela reação de um ácido com uma base, resultando em um equilíbrio iônico. Esses sais frequentemente melhoram a solubilidade e a estabilidade dos APIs, facilitando sua absorção no organismo. Os derivados de API são variantes químicas de um princípio ativo que podem apresentar propriedades aprimoradas ou modificadas para otimizar a eficácia terapêutica. Os sais de APIs são utilizados na formulação de medicamentos orais, injetáveis e tópicos. Além disso, os derivados de API podem melhorar a farmacocinética dos fármacos, permitindo, por exemplo, a liberação controlada de substâncias ativas.
Na CymitQuimica, oferecemos sais e derivados de APIs com a pureza e qualidade necessárias para pesquisa e desenvolvimento de formulações farmacêuticas.
Foram encontrados 79238 produtos de "Sais e Derivados de API"
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3,7-Dihydro-3,7-dimethyl-6-[(5-oxohexyl)oxy]-2H-purin-2-one
CAS:Fórmula:C13H18N4O3Cor e Forma:NeatPeso molecular:278.31O,O-Dimethyl Methylphosphonate
CAS:Produto Controlado<p>Applications O,O-Dimethyl Methylphosphonate is a commercially used preignition additive for gasoline, anti-foaming agent, plasticizer, stabilizer and antistatic agents.<br>References Jang, S.H., et al.: J. Korean. Phy. Soc., 55, 294 (2009); Schneider, B.B., et al.: Int. J. Mass. Spectro., 298, 45 (2010);<br></p>Fórmula:C3H9O3PCor e Forma:NeatPeso molecular:124.076Pyridin-3-yl Dimethylcarbamate
CAS:Produto Controlado<p>Applications Pyridin-3-yl dimethylcarbamate (cas# 51581-32-9) is a useful research chemical.<br></p>Fórmula:C8H10N2O2Cor e Forma:ColourlessPeso molecular:166.187-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide
CAS:Produto Controlado<p>Applications 7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.<br>References Rodgers, T. et al.: J. Med. Chem., 20, 591 (1977); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);<br></p>Fórmula:C19H22BrNO4S2Cor e Forma:NeatPeso molecular:472.42Dimiracetam
CAS:<p>Dimiracetam, a NMDA-receptor antagonist, is used potentially for the treatment of neuropathic pain.</p>Fórmula:C6H8N2O2Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:140.14Dichloronitromethane
CAS:Fórmula:CHCl2NO2Cor e Forma:Colourless to Pale Yellow OilPeso molecular:129.93Ramipril
CAS:Produto Controlado<p>Applications An antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite. Neuroprotective & Neuroresearch Product.<br>References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),<br></p>Fórmula:C23H32N2O5Cor e Forma:WhitePeso molecular:416.51FK-506-13C,D2 (Major) (Tacrolimus) (>85%)
CAS:Produto ControladoFórmula:CC43D2H67NO12Pureza:>85%Cor e Forma:NeatPeso molecular:807.024-(2-Aminophenyl)-3-morpholinone
CAS:<p>Applications 4-(2-Aminophenyl)-3-morpholinone is a reagent used in the preparation of various Morpholine based pharmaceuticals.<br>References Mederski, W., et al.: Bioorg. Med. Chem. Lett., 14, 3763 (2004), Roehrig, S., et al.: J. Med. Chem., 48, 5900 (2005),<br></p>Fórmula:C10H12N2O2Cor e Forma:Off White SolidPeso molecular:192.214Rivaroxaban-d4
CAS:Produto ControladoFórmula:C19H14D4ClN3O5SCor e Forma:White To Off-WhitePeso molecular:439.91(15R)-Bimatoprost Acid
CAS:Produto Controlado<p>Applications (15R)-Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost (B386820). (15R)-Bimatoprost Acid is a metabolically stable analog of PGF2α (P838625) and is a potent agonist for the FP receptor.<br>References Balapure, A.K. et al.: Biochem. Pharmacol., 38, 2375 (1989); Hellberg, M.R. et al.: J. Ocular Pharmacol. Ther., 19, 97 (2003); Krishna, P.M. et al.: J. Pharm. res., 4, 2381 (2011); Resul, B., et al.: J. Med. Chem., 36, 243 (1993)<br></p>Fórmula:C23H32O5Cor e Forma:NeatPeso molecular:388.497Macitentan
CAS:Produto Controlado<p>Applications Macitentan, is an orally active endothelin receptor antagonist used for pulmonary arterial hypertension.<br>References Emoto, N. Ensho to Men'eki, 20, 487 (2012);<br></p>Fórmula:C19H20Br2N6O4SCor e Forma:White To Off-WhitePeso molecular:588.27Ramipril-d3
CAS:Produto Controlado<p>Applications A labelled antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite.<br>References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),<br></p>Fórmula:C23H29D3N2O5Cor e Forma:NeatPeso molecular:416.51Trandolapril
CAS:Produto Controlado<p>Applications An antihypertensive. Angiotensin converting enzyme (ACE) inhibitor.<br>References Brown, N.L., et al.: Eur. J. Pharmacol., 148, 79 (1988), Kober, L., et al.: N. Engl. J. Med., 333, 1670 (1995), Malik, R.A., et al.: Lancet, 352, 1978 (1998)<br></p>Fórmula:C24H34N2O5Cor e Forma:NeatPeso molecular:430.54Diclofenac Amide
CAS:<p>Impurity Aceclofenac EP Impurity I/ Diclofenac USP Related Compound A<br>Applications A potential prodrug of Diclofenac and possible impurity during its commercial synthesis. Aceclofenac EP Impurity I; Diclofenac Impurity A<br>References Gaudiano, M.C., et al.: J. Pharm. Biomed. Anal., 32, 151 (2003), De Castro, W.V., et al.: Drug Develop. Ind. Pharm., 32, 1103 (2006),<br></p>Fórmula:C14H9Cl2NOCor e Forma:Light Yellow To BrownPeso molecular:278.13Iomeprol-d3
CAS:Produto Controlado<p>Applications Diagnostic aid (radiopaque medium).<br>References Gallotti, A., et al.: Eur. J. Radiol., 18, Suppl 1 S1(1994), Morisetti, A., et al.: Eur. J. Radiol., 18, Suppl 1 S21(1994).<br></p>Fórmula:C17H19D3I3N3O8Cor e Forma:Off-WhitePeso molecular:780.10Argatroban monohydrate
CAS:Produto ControladoFórmula:C23H36N6O5S·H2OCor e Forma:NeatPeso molecular:526.654-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol
CAS:Produto Controlado<p>Applications 4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.<br>References Asaki, T., et al.: Bioorg. Med. Chem., 15, 6692 (2007); Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);<br></p>Fórmula:C23H27N3OCor e Forma:NeatPeso molecular:361.48Repaglinide Acyl-β-D-glucuronide
CAS:<p>Applications A metabolite of Repaglinide (M7).<br></p>Fórmula:C33H44N2O10Cor e Forma:NeatPeso molecular:628.71Tolvaptan
CAS:Produto Controlado<p>Applications Tolvaptan is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).<br>References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000); Udelson, J., et al.: Circulation, 104, 2417 (2001); Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005); Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006);<br></p>Fórmula:C26H25ClN2O3Cor e Forma:White To Off-WhitePeso molecular:448.94
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