Sulfonamidas e Derivados
As sulfonamidas são compostos que contêm um grupo funcional sulfonamida (-SO₂NH₂), onde um átomo de enxofre está ligado a um grupo amino. Foram um dos primeiros antibióticos sintéticos usados na medicina, inibindo a síntese do ácido fólico nas bactérias, o que lhes confere propriedades antimicrobianas. São utilizadas principalmente para tratar infeções bacterianas, embora seu uso tenha diminuído devido à resistência antimicrobiana. Além do uso como antibióticos, as sulfonamidas também têm aplicações no tratamento de doenças como a malária e doenças inflamatórias intestinais.
Na CymitQuimica, oferecemos sulfonamidas e seus derivados com alto grau de pureza para pesquisa em microbiologia e desenvolvimento farmacêutico.
Foram encontrados 2592 produtos de "Sulfonamidas e Derivados"
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4-Acetaminophen-d3 Sulfate Potassium Salt
CAS:Produto Controlado<p>Applications 4-Acetaminophen-d3 Sulfate Potassium Salt is a deuterium labeled metabolite of Acetaminophen (A161220) (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961)(2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Fórmula:C8H5D3KNO5SCor e Forma:NeatPeso molecular:272.33Saccharin-13C6
CAS:<p>Applications It is a labelled non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing.<br>References Taylor, J.D., et al.: Food Cosmet. Toxicol., 6, 313 (1968), Arnold, D.L., et al.: Fundam. Appl. Toxicol., 4, 674 (1984),<br></p>Fórmula:C13C6H5NO3SCor e Forma:Off-WhitePeso molecular:189.14Glyburide-d11
CAS:Produto ControladoFórmula:C23D11H17ClN3O5SCor e Forma:Off-WhitePeso molecular:505.072-Chloronicotinic Acid
CAS:Produto Controlado<p>Applications 2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.<br>References Patel, N. et al.: Saudi Pharm. J., 18, 129 (2010); Patel, N. et al.: J. Sci. Islam Repub. Iran., 21, 121 (2010);<br></p>Fórmula:C6H4ClNO2Cor e Forma:NeatPeso molecular:157.55N-Desbutyl-N-propyl Bumetanide
CAS:Produto Controlado<p>Applications Bumetanide (B689550) analogue as diuretic and antihypertensive. Bumetanide impurity.<br>References Feit, P.W., et al.: J. Med. Chem., 14, 432 (1971),<br></p>Fórmula:C16H18N2O5SCor e Forma:NeatPeso molecular:350.3894-desamino Dapsone
CAS:<p>Applications 4-Phenylsulfonylaniline is used in the preparation of novel Flufenamic acid analogues as inhibitors of androgen receptor mediated transcription.<br>References Kemppainen, J., et al.: J. Biol. Chem., 267, 968 (1992), Amler, L., et al.: Cancer Res., 60, 6134 (2000), Klotz, L., et al.: Clin. Prostate Cancer, 3, 215 (2005),<br></p>Fórmula:C12H11NO2SCor e Forma:White To Off-WhitePeso molecular:233.293-Hydroxyacetaminophen-D3
CAS:Produto Controlado<p>Applications 3-Hydroxyacetaminophen-d3 is deuterium labeled 3-Hydroxyacetaminophen (H714750). 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Fórmula:C82H3H6NO3Cor e Forma:NeatPeso molecular:170.18N-(2,3-Dimethylphenyl) Mefenamic Acid Carboxamide
CAS:Produto Controlado<p>Impurity Mefeneic Acid EP Impurity B<br>Applications N-(2,3-Dimethylphenyl) Mefenamic Acid Carboxamide is a derivative of Mefenamic Acid (M205050); an anti-inflammatory agent and analgesic.<br>References Winder, C.V., J. Pharmacol. Exp. Ther., 138, 405 (1962)<br></p>Fórmula:C23H24N2OCor e Forma:NeatPeso molecular:344.454-(2-Aminoethyl)benzenesulfonamide
CAS:Produto ControladoFórmula:C8H12N2O2SCor e Forma:NeatPeso molecular:200.26Zonisamide N,N-Dimethylformimidamide
CAS:<p>Applications Zonisamide related compound C.<br></p>Fórmula:C11H13N3O3SCor e Forma:White To Off-WhitePeso molecular:267.30Acemetacin
CAS:Produto Controlado<p>Applications Acemetacin is a non-steroidal anti-inflammatory agent and used to treat rheumatic disease and other musculoskeletal disorders (1,2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Jacobi, H. and Dell, H. D.: Arzneimittelforschung 30, 1398 (1980) (2) Moore, R. A., et al.: Cochrane Database Syst Rev. 8,CD007589 (2009)<br></p>Fórmula:C21H18ClNO6Cor e Forma:YellowPeso molecular:415.82Sulfadiazine-d4
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications The isotopically labelled drug Sulfadiazine. Antibacterial.<br>References Bohni, et al.: Chemotherapy, 14, 195 (1969), Carr, et al.: Antimicrob. Agents Chemother., 4, 585 (1973), Stober, H., et al.: Anal. Profiles Drug Subs., 11, 523 (1982),<br></p>Fórmula:C10D4H6N4O2SCor e Forma:Light YellowPeso molecular:254.35-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine
CAS:<p>Stability Hygroscopic<br>Applications 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine, is a derivative of Trimethoprim (T795615), an antibacterial agent. 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine, is a possible potent and selective inhibitor targeting dihydrofolate reductase of C. hominis, used for the treatment of Cryptosporidiosis.<br>References Popov, V. M., et al.: Bioorg. Med. Chem. Lett., 16, 4366 (2006); Brogden, R.N., et al.: Drugs, 23, 405 (1982);<br></p>Fórmula:C14H16N4O4Cor e Forma:Light Yellow To OrangePeso molecular:304.30Sulfasalazine
CAS:Produto Controlado<p>Applications Sulfasalazine is an anti-inflammatory (gastrointestinal). Sulfasalazine has been used in granulomatous colitis.<br>References Schroder, H., et al.: Clin. Pharmacol. Ther.,13, 539 (1972), McDonnell, J.P., et al.: Anal. Profiles Drug Subs., 5, 515 (1976), Klotz, U., et al.: Clin. Pharmacokinet.,10, 285 (1985),<br></p>Fórmula:C18H14N4O5SCor e Forma:Yellow To Dark OrangePeso molecular:398.394-Carboxy-a-methylbenzeneacetic Acid
CAS:Produto ControladoFórmula:C10H10O4Cor e Forma:WhitePeso molecular:194.18Sulfamonomethoxine-d4
CAS:Produto Controlado<p>Applications Labelled Sulfamonomethoxine. Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim are used for treating porcine unknown hyperpyrexia.<br>References Bridges, et al.: Biochem. J., et al.: 96, 829 (1965), Hong, Y.-L., et al.: Antimicrob. Agents Chemother., 39, 1756 (1995)<br></p>Fórmula:C11H8D4N4O3SCor e Forma:NeatPeso molecular:284.33Mefenamic Acid-d3 (major)
CAS:Produto ControladoFórmula:C15H12D3NO2Cor e Forma:Light YellowPeso molecular:244.32-Phenoxylaniline
CAS:Produto Controlado<p>Impurity Nimesulide EP Impurity C<br>Stability Hygroscopic<br>Applications 2-Phenoxylaniline (Nimesulide EP Impurity C) is an impurity of Nimesulide (N477500) which is an antiinflammatory agent that preferentially inhibits COX-2 over COX-1.<br>References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)<br></p>Fórmula:C12H11NOCor e Forma:Off-WhitePeso molecular:185.22Sulfachlorpyridazine-d4
CAS:Produto Controlado<p>Applications Labelled analogue of Sulfachlorpyridazine, an antibacterial compound.<br>References Wammer, K.: Environ. Toxicol. Chem. 25, 1480 (2006);<br></p>Fórmula:C10H5D4ClN4O2SCor e Forma:NeatPeso molecular:288.754-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide Benzoic Acid
CAS:<p>Applications An impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Fórmula:C21H16Cl2N2O3Cor e Forma:NeatPeso molecular:415.27p-Butyl Ibuprofen
CAS:Produto Controlado<p>Applications p-Butyl Ibuprofen (cas# 3585-49-7) is a useful research chemical.<br></p>Fórmula:C13H18O2Cor e Forma:Light YellowPeso molecular:206.28Xipamide-d6
CAS:Produto Controlado<p>Applications A labelled diuretic and antihypertensive.<br>References Wagieh, N., et al.: Drug Test. Anal., 2, 113 (2010), Prado-Prado, F., et al.: Bioorg. Med. Chem., 18, 2225 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),<br></p>Fórmula:C15H9D6ClN2O4SCor e Forma:NeatPeso molecular:360.854-Nitroso Sulfamethoxazole, > 90%
CAS:Produto Controlado<p>Applications A Sulfamethoxazole metabolite.<br>References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),<br></p>Fórmula:C10H9N3O4SPureza:>90%Cor e Forma:NeatPeso molecular:267.26Limaprost-d3 (>90%)
CAS:Produto Controlado<p>Applications Labelled Limaprost (L461500). Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Fórmula:C22H33D3O5Pureza:>90%Cor e Forma:NeatPeso molecular:383.54N-Acetyl Sulfamethoxazole
CAS:<p>Impurity Sulfamethoxazole EP Impurity A<br>Applications A metabolite of Sulfamethoxazole.<br>References Ciolino, H., et al.: Cancer Res., 58 , 2754 (1998), Larsen, T., et al.: Environ. Sci. Technol., 35, 192 (2001), Heberer, T., et al.: Toxicol. Lett., 131, 5 (2002), Larsen, T., et al.: J. Biotechnol., 113, 295 (2004),<br></p>Fórmula:C12H13N3O4SCor e Forma:Off-WhitePeso molecular:295.31Mefruside
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Mefruside is a diuretic used for the treatment of edema and hypertension.<br>References Johansen, A., et al.: Euro. J. Epidemiol., 27, 63 (2012); Hasegawa, Y., et al.: Blood. Press. Supple., 1, 10 (2010);<br></p>Fórmula:C13H19ClN2O5S2Cor e Forma:Off-WhitePeso molecular:382.88Ibuprofen Related Compound (2,3-Dihydroxypropyl 2-(4-Isobutylphenyl)Propanoate)
CAS:Produto Controlado<p>Applications Ibuprofen Related Compound is used for research purposes on Ibuprofen soft capsules for the investigation of unknown impurities.<br>References Bao, S., et al.: Yaowu Fenxi Zazhi, 35, 97 (2015)<br></p>Fórmula:C16H24O4Cor e Forma:ColourlessPeso molecular:280.36Ethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide(Piroxicam Impurity H)
CAS:Produto Controlado<p>Impurity Piroxicam EP Impurity H<br>Applications Piroxicam Impurity H.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Fórmula:C11H11NO5SCor e Forma:White To Off-WhitePeso molecular:269.271,3-Dipalmitoyl-2-chloropropanediol-d5
CAS:Produto Controlado<p>Applications Labelled 1,3-Dipalmitoyl-2-chloropropanediol is used in the synthesis of some prodrugs of Piroxicam and Lornoxicam to improve their bioavailability.<br>References Passarotti, C.M., et al.: Bollettino Chimico Farmaceutico, 134, 161 (1995),<br></p>Fórmula:C352H5H62ClO4Cor e Forma:WhitePeso molecular:592.39Hydrochlorothiazide-d2
CAS:Produto Controlado<p>Applications Hydrochlorothiazide-d2 is the labeled analogue of Hydrochlorothiazide (H714560), a carbonic anhydrase inhibitor as a diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961); Deppeler, H.P., et al.: Anal. Profiles Drug Subs., 10, 405 (1981)<br></p>Fórmula:C72H2H6ClN3O4S2Cor e Forma:WhitePeso molecular:299.752-(p-Tolyl)propionic Acid
CAS:Produto Controlado<p>Impurity Ibuprofen EP Impurity D<br>Applications 2-(p-Tolyl)propionic acid (Ibuprofen EP Impurity D) is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.<br>References Jia, C., et al.: Science, 287, 1992 (2000), Yu, J., et al.: Org. Biomol. Chem., 4, 4041 (2006),<br></p>Fórmula:C10H12O2Cor e Forma:White To Off-WhitePeso molecular:164.20N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide
CAS:Produto Controlado<p>Impurity Acetazolamide EP Impurity A<br>Applications N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide is an impurity of Acetazolamide (A161500). Acetazolamide EP Impurity A<br>References Zarghi, A., et al.: J. Pharm. Biomed. Anal., 28, 169 (2002), Subbarao, D., et al.: J. Chromatogr., 67, 841 (2008),<br></p>Fórmula:C4H4ClN3OSCor e Forma:White To Off-WhitePeso molecular:177.61Descyclohexylformamide Glipizide
CAS:Produto Controlado<p>Impurity Glipizide EP Impurity D<br>Applications 4-[β-(6-Methylpyrazinyl-2-carboxamido)ethyl]benzene Sulfonamide (Glipizide EP Impurity D) is an intermediate in the synthesis of the impurity 5-Desmethyl-6-methyl Glipizide (D292550).<br></p>Fórmula:C14H16N4O3SCor e Forma:NeatPeso molecular:320.37Acetazolamide-d3
CAS:Produto Controlado<p>Applications Carbonic anhydrase inhibitor. Diuretic.<br>References Parasrampuria, J., et al.: Anal. Profiles Drug Subs. Excip. 22, 1 (1993),<br></p>Fórmula:C4H3D3N4O3S2Cor e Forma:Off White To Light YellowPeso molecular:225.26Acetaminophen-d3
CAS:Produto Controlado<p>Applications Acetaminophen-d3 is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C82H3H6NO2Cor e Forma:WhitePeso molecular:154.18Sulfadimethoxine-d4
CAS:Produto Controlado<p>Applications Sulfadimethoxine-d4 is a isotope labeled version of Sulfadimethoxine (S699060), a sulfonamide antibiotic.<br>References Seki, et al.: Arzneim.-Forsch., 15, 1441 (1965), Bohni, et al.: Chemotherapy, 14, 195 (1969),<br></p>Fórmula:C12H10D4N4O4SCor e Forma:NeatPeso molecular:314.35Acetaminophen-d4 (major)
CAS:Produto Controlado<p>Applications Acetaminophen-d4 (major) is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C82H4H5NO2Cor e Forma:Off-WhitePeso molecular:155.19rac-Acetaminophen Mercapturate-d5 (Major)
CAS:Produto Controlado<p>Applications rac-Acetaminophen Mercapturate-d5 (Major), is a labeled analogue and free acid of 3-(N-Acetyl-L-cystein-S-yl) Acetaminophen Disodium Salt (A172100), which is a metabolite of Acetaminophen (A161220). Acetaminophen is an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References van der Hooft, J.,et al.: Metabolomics, 12, 1 (2016)<br></p>Fórmula:C13H11D5N2O5SCor e Forma:NeatPeso molecular:317.37Hydrochlorothiazide Dimer
CAS:<p>Impurity Hydrochlorothiazide EP Impurity C<br>Applications N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonamide (Hydrochlorothiazide EP Impurity C) is an impurity in bulk Hydrochlorothiazide. Dimer Impurity C.<br>References Daniels, S.L., et al.: J. Pharm. Sci., 70, 211 (1981), Fang, X., et al.: Pharm. Res., 14, 691 (1997),<br></p>Fórmula:C15H16Cl2N6O8S4Cor e Forma:Off-WhitePeso molecular:607.498-Methyl Etodolac
CAS:Produto Controlado<p>Impurity Etodolac EP Impurity B<br>Applications 8-Methyl Etodolac (Etodolac EP Impurity B) is an impurity of Etodolac (E933100) which was examined for mutagenicity in reverse mutation tests on bacteria. Etodolac impurity B.<br>References Franke, L., et al.: J. Med. Chem., 48, 6997 (2005), Fox, T., et al.: Curr. Top Med. Chem., 6, 1579 (2006),<br></p>Fórmula:C16H19NO3Cor e Forma:WhitePeso molecular:273.334-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride
CAS:<p>Applications 4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride is a derivative of (4-Methoxyphenyl)hydrazine Hydrochloride (M265880). It is a useful synthetic intermediate for the preparation of Indomethacin (I641000); a potent, time-dependent, nonselective inhibitor of the cyclooxygenase enzymes COX-1 and COX-2.<br>References Blobaum, Anna L., et al.: ACS Med. Chem. Lett., 4(5), 486-490 (2013); Prusakiewicz, Jeffery J., et al.: Biochemistry, 43(49), 15439-15445 (2004)<br></p>Fórmula:C14H13ClN2O2·HClCor e Forma:NeatPeso molecular:313.18Sulfadiazine Sodium Salt
CAS:Produto Controlado<p>Applications Sulfadiazine Sodium Salt can be used as reactant/reagent in preparation and crystal structure of aminophenyl sulfonamide tetrahalides, hydrochloride and hydrobromide cocrystals with iodine.<br>References Pan, F., et al.: CrystEngComm, 17, 6641 (2015)<br></p>Fórmula:C10H9N4NaO2SCor e Forma:Off-WhitePeso molecular:272.264-Deschloro-4-(2-furanylmethyl)amino Furosemide
CAS:<p>Impurity Furosemide EP Impurity D<br>Applications 4-Deschloro-4-(2-furanylmethyl)amino Furosemide (Furosemide EP Impurity D) is a Furosemide (F865000) Impurity.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979)<br></p>Fórmula:C17H17N3O6SCor e Forma:White To Dark BrownPeso molecular:391.405-Amino-1,3,4-thiadiazol-2-sulfonamide
CAS:Produto ControladoFórmula:C2H4N4O2S2Pureza:99%Cor e Forma:NeatPeso molecular:180.21N-Acetyl Sulfadiazine
CAS:Produto ControladoFórmula:C12H12N4O3SCor e Forma:Off-WhitePeso molecular:292.313-(p-Chlorophenyl)-3-hydroxyphthalimidine
CAS:Produto Controlado<p>Applications 3-(p-Chlorophenyl)-3-hydroxyphthalimidine is an analog of Chlorthalidone (C427500) and has potential antidiuretic and hyperglycemic activities.<br>References Wales, J.K., et al.: P. Soc. Exp. Biol. Med., 128, 581 (1968)<br></p>Fórmula:C14H10ClNO2Cor e Forma:White To Off-WhitePeso molecular:259.69rac cis-3-Hydroxy Glyburide
CAS:Produto Controlado<p>Applications rac cis-3-Hydroxy Glyburide is a metabolite of Glyburide which is used as an antidiabetic (MII-metabolite).<br>References Heptner, W., et al.: Pharmaceut. Res., 5, 215 (1984), Rydberg, T., et al.: Br. J. Clin. Pharm., 43, 373 (1997),<br></p>Fórmula:C23H28ClN3O6SCor e Forma:NeatPeso molecular:510.00
