
Sulfonamidas e Derivados
As sulfonamidas são compostos que contêm um grupo funcional sulfonamida (-SO₂NH₂), onde um átomo de enxofre está ligado a um grupo amino. Foram um dos primeiros antibióticos sintéticos usados na medicina, inibindo a síntese do ácido fólico nas bactérias, o que lhes confere propriedades antimicrobianas. São utilizadas principalmente para tratar infeções bacterianas, embora seu uso tenha diminuído devido à resistência antimicrobiana. Além do uso como antibióticos, as sulfonamidas também têm aplicações no tratamento de doenças como a malária e doenças inflamatórias intestinais.
Na CymitQuimica, oferecemos sulfonamidas e seus derivados com alto grau de pureza para pesquisa em microbiologia e desenvolvimento farmacêutico.
Foram encontrados 2589 produtos de "Sulfonamidas e Derivados"
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Tiafenacil
CAS:<p>Applications Tiafenacil is a uracil herbicide used as a pesticide for the prevention and control of plants.<br>References Peng, X., et al. Faming Zhuanli Shenqing, 68pp Patent 2018 CODEN:CNXXEV<br></p>Fórmula:C19H18ClF4N3O5SCor e Forma:Off White SolidPeso molecular:511.87Indomethacin 1-Glycerin Ester
CAS:<p>Applications Indometacin 1-Glycerin Ester was synthesized and evaluated for anti-flammatory activity in the rate paw carrageenin edema essay.<br>References Paris, Gerard. , et al.: J. Med. Chem, 23, 9 (1980)<br></p>Fórmula:C22H22ClNO6Cor e Forma:NeatPeso molecular:431.87Metolazone
CAS:Produto Controlado<p>Applications A diruetic. An antihypertensive.<br>References Curry, C.L., et al.: Clin. Ther., 9, 47 (1986), Kiyingi, A., et al.: Lancet, 335, 29 (1990)<br></p>Fórmula:C16H16ClN3O3SCor e Forma:NeatPeso molecular:365.83Sulfadiazine Silver Salt
CAS:Produto Controlado<p>Applications Coordination compound. Antibacterial.<br>References Bohni, et al.: Chemotherapy, 14, 195 (1969), Carr, et al.: Antimicrob. Agents Chemother., 4, 585 (1973), Stober, H., et al.: Anal. Profiles Drug Subs., 11, 523 (1982),<br></p>Fórmula:C10H9N4O2S·AgCor e Forma:NeatPeso molecular:357.14Benzeneacetonitrile
CAS:Produto Controlado<p>Applications Benzeneacetonitrile is a volatile compound released from apple trees infested with light brown apple moth larvae. It is also used in the synthesis of phenobarbital (P316760), methylphenidate (M325880), and other amphetamines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Suckling, D. et al.: J. Agr. Food. Chem., 60, 9562 (2012); Cuevas-G. et al.: Int. J. Food. Sci. Technol., 47, 1378 (2012)<br></p>Fórmula:C8H7NCor e Forma:NeatPeso molecular:117.15(4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide
CAS:Produto Controlado<p>Applications (4R,6S)-4H-Thieno[2,3-b]thiopyran-4-ol, 5,6-dihydro-6-methyl-,7,7-dioxide is an analog of topically-active carbonic anhydrase inhibitor MK-507 also commonly known as Dorzolamide (D535100).<br>References Blacklock, T., et al.: J. Org. Chem., 58, 1672 (1993); Tempkin, O., et al.: Tetrahedron: Asym., 7, 2721 (1996)<br></p>Fórmula:C8H10O3S2Cor e Forma:NeatPeso molecular:218.29Sulfamethizole-d4
CAS:Produto Controlado<p>Applications Isotope Labelled Sulfamethizole is a sulfonamide based antibiotic that exhibit bactericidal activities towards gram-negative bacteria. Sulfamehizole was shown to be effective in treating gram-negative Bacillus AmpC enzyme in elderly patients with lower respiratory tract infection and as well as against microbs responsible for tuberculosis.<br>References Mondelli, M., et al.: J. Molec. Struct., 1036, 180 (2013); Leelakrishnana, S., et al.: Adv. App. Sci. Res., 3, 3502 (2012); Ghoreishi, S.M., et al.: Anal. Lett., 46, 323 (2012);<br></p>Fórmula:C92H4H6N4O2S2Cor e Forma:NeatPeso molecular:274.36N-Nitroso Furosemide-d5
Produto ControladoFórmula:C12D5H5ClN3O6SCor e Forma:NeatPeso molecular:364.7738-Isopropyl Etodolac
CAS:Produto Controlado<p>Impurity Etodolac EP Impurity D<br>Applications 8-Isopropyl Etodolac (Etodolac EP Impurity D) is an impurity in the synthesis of Etodolac (E933100), may have use in the treatment of myeloma. COX-1/COX-2/β-catenin inhibitors, or anti-inflammatory agent.<br>References Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001);<br></p>Fórmula:C18H23NO3Cor e Forma:NeatPeso molecular:301.38Benzoxazolemethanesulfonamide-N-(6-methyl-hexanoate)
CAS:Produto Controlado<p>Applications Intermediate of Zonisamide-N-(6-hexanoic acid).<br></p>Fórmula:C15H20N2O5SCor e Forma:NeatPeso molecular:340.394-Hydroxy Triamterene Sulfate-d4, Sodium Salt
CAS:Produto Controlado<p>Applications Isotope labelled 4-hydroxy triamterene sulfate sodium salt a metabolite of Triamterne, a diuretic agent.<br>References Vollmer, G., et al.: Arzneim.-Forsch., 31, 529 (1981), Gilfrich, H.J., et al.: Eur. J. Clin. Pharmacol., 25, 237 (1983),<br></p>Fórmula:C12H6D4N7NaO4SCor e Forma:NeatPeso molecular:375.333-Azabicyclo[3.3.0]octane Hydrochloride
CAS:Produto Controlado<p>Applications 3-Azabicyclo[3.3.0]octane Hydrochloride is a reactant in the preparation of substituted pyrimidines derivatives as novel hedgehog signaling pathway inhibitors.<br>References Xin, M. et al.: Med. Chem. Res., 23, 3784 (2014); Xin, M. et al.: Bioorg. Med. Chem. Lett., 24, 983 (2014);<br></p>Fórmula:C7H13N·ClHCor e Forma:White To Light YellowPeso molecular:147.651-[1-(4-Chlorobenzoyl)-5-hydroxy-2-methyl-1H-indole-3-acetate]β-D-Glucopyranuronic Acid
CAS:Produto Controlado<p>Stability Hygroscopic, Moisture Sensitive<br>Applications 1-[1-(4-Chlorobenzoyl)-5-hydroxy-2-methyl-1H-indole-3-acetate]β-D-Glucopyranuronic Acid is an analog of Indomethacin Acyl-β-D-glucuronide a metabolite of Indomethacin (I641000). Acyl glucuronides have been implicated in the toxicity of many xenobiotics and marketed drugs.<br>References Abid, A., et al.: Biochem. Pharmacol., 50, 557 (1995), Gamage, N., et al.: Toxicol. Sci., 90, 5 (2006), Cerveny, L., et al.: Drug Metab. Dispos., 35, 1032 (2007), Hayeshi, R., et al.: Eur. J. Pharm. Sci., 35, 383 (2008),<br></p>Fórmula:C24H22ClNO10Cor e Forma:NeatPeso molecular:519.894-Amino-4'-chlorodiphenyl Sulfone
CAS:Produto Controlado<p>Applications 4-Amino-4'-chlorodiphenyl sulfone is a substituted 4-aminodiphenylsulfone as Escherichia coli dihydropteroate synthase inhibitor.<br>References Lopez de Compadre, R.L., et al.: J. Med. Chem., 31, 2315 (1988),<br></p>Fórmula:C12H10ClNO2SCor e Forma:Off-White To Light YellowPeso molecular:267.73rac-trans Dorzolamide Hydrochloride
CAS:Produto Controlado<p>Applications rac-trans Dorzolamide is an impurity of Dorzolamide (D535100).<br>References Casini, A., et al.: Bioorg. Med. Chem. Lett., 13, 841 (2003), Clare, B., et al.: Bioorg. Med. Chem., 13, 2197 (2005),<br></p>Fórmula:C10H17ClN2O4S3Cor e Forma:NeatPeso molecular:360.9Dapsone N-β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic, unstable in solution<br>Applications Dapsone N-β-D-Glucuronide is the glucuronide conjugate and main urinary metabolite of the antibacterial Dapsone (D193250).<br>References Andoh, B.Y.A. et al.: Xenobiotica, 4, 571 (1974); Ogiya, S. et al.: Yakug. Zas., 81, 349 (1961);<br></p>Fórmula:C18H19N2NaO8SCor e Forma:NeatPeso molecular:446.41Indomethacin 1-Menthol ester
CAS:Produto Controlado<p>Applications Indomethacin terpenoids' esters were synthesized and assessed both in vitro and in vivo as indomethacin dermal prodrugs.<br>References Bonina,, Francesco. , et al.: European Journal of Pharmaceutical Sciences, 14, 123 (2001),<br></p>Fórmula:C29H34ClNO4Cor e Forma:NeatPeso molecular:496.0385-Amino-3-(4-sulfonylphenyl)salicyclic Acid Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 5-Amino-3-(4-sulfonylphenyl)salicyclic Acid Sodium Salt is an impurity of mesalamine (M258100), which is the active metabolite of Sulfasalazine (S699084). Anti-inflammatory (gastrointestinal).<br>References Friedman, G., et al.: Am. J. Gastroenterol., 81, 141 (1986); Tursi A., Expert Opin. Pharmacother., 6, 69 (2005);<br></p>Fórmula:C13H11NO6S•x(Na)Cor e Forma:NeatPeso molecular:309.29 + x(22.99)8-Propyl Etodolac
CAS:Produto Controlado<p>Impurity Etodolac EP Impurity E<br>Applications 8-Propyl Etodolac (Etodolac EP Impurity E) is an impurity in the synthesis of Etodolac (E933100), may have use in the treatment of myeloma. COX-1/COX-2/β-catenin inhibitors.<br>References Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001);<br></p>Fórmula:C18H23NO3Cor e Forma:NeatPeso molecular:301.38
