Biblioteca de Compostos MTC

Stability Light Sensitive
Applications N-Nitroso-di-n-butylamine (cas# 924-16-3) is a compound useful in organic synthesis.

Applications N-Nitrosodiethylamine-d10 is a labelled form of N-Nitrosodiethylamine (N525465) which is a widely occurring nitrosamine that is one of the most important environmental carcinogens primarily inducing tumors of liver.NDMA and NDEA were found as an impurity in generic versions of valsartan, losartan and irbesartan.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Oda, Y., et al.: Mutation Research, Genetic Toxicology and Environmental Mutagenesis, 584, 1 (2005); Yamazaki, H., et al.: Carcinogenesis, 13, 1789 (1992);Chem. and Eng. News, p.5, Feb. 25, 2019

Applications N-Methyl-N’-nitrosopiperazine-d4 is the isotope labelled analog of N-Methyl-N’-nitrosopiperazine (M325800), which is used as a reagent in the organic synthesis of several compounds including that of (4-methoxyphenoxy)acetic and (3,4,5-trimethoxyphenoxy)acetic acid amides and hydrazides which display antimicrobial and anthelmintic properties and may act as potential neurotropic and cardiovascular agents. N-Methyl-N’-nitrosopiperazine also diplayed strong nasal carcinogenity and genotoxicity toward nasal cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Valenta, V., et al.: Collect. Czech. Chem. C., 52, 3013 (1987); Klein, R., et al.: Carcinogenesis, 20, 1629 (1999);

Stability Light Sensitive
Applications N-Ethyl-N-nitroso-2-propanamine is a building block used in synthesis of amino acids, peptides, and proteins.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Piotrowska, K., et al.: Synthetic Communications, Vol. 9, Issue 8 (1979);

Stability Light Sensitive
Applications N-Methyl-N’-nitrosopiperazine was used as a reagent in the organic synthesis of several compounds including that of (4-methoxyphenoxy)acetic and (3,4,5-trimethoxyphenoxy)acetic acid amides and hydrazides which display antimicrobial and anthelmintic properties and may act as potential neurotropic and cardiovascular agents. N-Methyl-N’-nitrosopiperazine also diplayed strong nasal carcinogenity and genotoxicity toward nasal cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Valenta, V., et al.: Collect. Czech. Chem. C., 52, 3013 (1987); Klein, R., et al.: Carcinogenesis, 20, 1629 (1999);

Applications N-Nitrosodiisobutylamine is a nitrosoamine compound that shows carcinogenic effect.
References Scanlan, R., et al.: Cancer Res., 43, 2435 (1983), Spiegelhalder, B., et al.: Carcinogenesis, 4, 1147 (1983), Lijinsky, W., et al.: Mutat. Res., 443, 129 (1999), Robichova, S., et al.: Chem. Biol. Interact., 148, 163 (2004),

Applications Methylpropylnitrosamine is used in biological studies as human liver microsomal cytochrome P-450 enzymes which are involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002.
References Shimada, T., et al.: Cancer Res., 48, 3218 (1989);

Applications N-tert-Butyl-N-ethylnitrosamine is a tyrosinase inhibitor and a possible carcinogen.
References Yuan, Jintao, et al.: Chem. Res. in Toxic., 24(12), 2269-2279 (2011);Ponce, Yovani M., et al.: QSAR & Combi. Sci., 26(4), 469-487 (2007)

Applications N-Nitrosodimethylamine-d6 (1.0 mg/mL in Methanol) is a highly toxic semi-volatile organic compound and a suspected human carcinogen. It induces liver tumors in rats after chronic exposure to low doses (1,2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
References Chem. and Eng. News, p.5, Feb. 25, 2019