Fitoquímicos

Applications Notoginsenoside R1 acts as an anti-inflammatory agent, inhibiting TNF-α induced PAI-1 production in aortic smooth muscle cells in humans.
References Zhang, H. et al.: Vasc. Pharmacol., 44, 224 (2006);

Applications A hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 and 42.93 μM, respectively. Recent studies suggest that it may have antiproliferative and anticancer properties.
References Girennavar, B. et al.: Bororg. Med. Chem., 14, 3684 (2007); Girennavar, B. et al..: J. Food Sci., 72, C417 (2007); Joa, H. et al.: J. Nat. Prod., 74, 1513 (2011); Hirata, T. et al.: Bioorg. Med. Chem.