Monossacáridos

<p>Applications Benzyl β-D-Glucopyranoside (cas# 4304-12-5) is a compound useful in organic synthesis.<br>References Yoshikawa, M., et al.: Chem. Pharm. Bull., 56, 1297 (2008), Takeda, Y., et al.: J. Nat. Med., 62, 476 (2008),<br></p>

<p>Applications Ethylmalonic Acid is used as a diagnostic agent used in the diagnosis of Ethylmalonic encephalopathy which is a rare autosomal recessive inborn error of metabolism.<br>References Baertling, F. et al.: Eur. J. Pediat., 173, 1719 (2014); Sudo, Y. et al.: Hu,am Genome Var., 1, 15016 (2014);<br></p>

<p>Applications D-Glucose is a aldohexose sugar that is very rare in nature but has been found in archaea, bacteria and other eukaryotes. Gulose is the C-3 Epimer of galactose (G155250).<br>References Sun, Y.X., et al.: Biosci. Biotech. Biochem., 70, 598 (2006); Bhuiyan, S.H., et al.: J. Biosci. Bioengin., 88, 567 (1999);<br></p>

<p>Applications 1,6-Anhydro-β-D-glucopyranose is a carbohydrate contains in liquid smoke flavorings.<br>References Kim, K., et al.: Agric. Biol. Chem., 38, 53 (1974), Guillen, M., et al.: Food Chem., 58, 97 (1997), Guillen, M., et al.: J. Agric. Food Chem., 46, 1276 (1998),<br></p>

<p>Applications Oxalic Acid Ethyl Ester is a useful synthetic intermediate. It is used to synthesize 2-substituted 3-aryl-4(3H)-quinazolinones with anticonvulsant activities. It is also used to prepare nonbenzamidine tetrazole derivatives as factor Xa inhibitors.<br>References Wolfe, J., et al.: J. Med. Chem., 33, 161 (1009); Quan, M., et al.: bioorg. Med. Chem. Lett., 13, 369 (2003)<br></p>

<p>Applications Monosaccharide anhydrides, new markers of toasted oak wood used for ageing wines and distillates.<br>References Goldberg, D., et al.: J. Agric. Food Chem., 47, 3978 (1999), Fu, P., et al.: Environ. Sci. Technol., 43, 286 (2009),<br></p>

<p>Stability Hygroscopic<br>Applications A constituent of certain mucopolysaccharides.<br>References Hoffman, P., et al.: Science, 124, 1252 (1956), Meyer, K: Biochim et Biophys. Acta, 21, 506 (1956), Cifonelli, J.A., et al.: Federation Proc., 16, 165 (1957), Cifonelli, J.A., et al.: J. Biol. Chem., 233, 541 (1958)<br></p>

<p>Applications Ethyl β-D-Thiogalactopyranoside (cas# 56245-60-4) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications A derivative of D-Mannosamine (M167000).<br>References Pukanud, P. et al.: Drug Delivery, 16, 289 (2009);<br></p>

<p>Applications An inhibitor of the enzyme glucose dehydrogenase.<br>References Cozier, G.E. et al.: Biochem. J., 340, 639 (1999);<br></p>

<p>Applications A carbohydrate metabolism regulator that has been shown to inhibit gluconeogenesis from lactate plus pyruvate and from substrates that enter the gluconeogenic pathway as triose phosphate.<br>References Joet, T., et al.: Biochem. J., 381, 905 (2004), Girardin, E., et al.: J. Biol. Chem., 280, 38059 (2005), Nghiem, N., et al.: App. Biochem. Biotechnol., 141, 335 (2007),<br></p>

<p>Applications α-Methylglyceric Acid is a biogenic secondary organic aerosol used in air quality diagnosis.<br>References Ru, P., et. al.: Environ. Sci. Technol., 48, 8491 (2014); Napelenok, S.L., et. al.: Environ. Sci. Technol., 48, 464 (2014); Stone, E.A., et. al.: Environ. Chem., 9, 263 (2012)<br></p>

<p>Applications D-Erythrulose is a tetrose carbohydrate that is used in various self-tanning cosmetics combined with dihydroxyacetone.<br>References Maeda, M., et al.: J. Biochem., 123, 602 (1998); Baykal, A., et al.: Bioorg. Chem., 34, 380 (2006);<br></p>

<p>Stability Hygroscopic<br>Applications D-(+)-Cellotriose (cas# 33404-34-1) is a compound useful in organic synthesis.<br></p>

<p>Applications D-Idose is a monosaccharide that is an important component of dermatan sulfate and heparan sulfate.<br>References Olsen, S.G., et al.: J. Biol. Chem., 264, 15982 (1989);<br></p>

<p>UDP-2-deoxy-2-fluoro-D-glucose sodium salt (UDPFG) is a fluorinated analog of the sugar donor, UDP-glucose. It is an acceptor for the enzyme, glycosylation protein glucosyltransferase, which catalyzes the transfer of glucose to proteins. This compound has been shown to be an activating sugar donor in vitro and in vivo. In addition, it was found that UDFG can bind to the active site of glucosyltransferase in a hydrogen bond interaction that may be important for catalysis.</p>

<p>L-Fucose is an aldohexose that is used as the building block for various glycoproteins and glycolipids. It is found in human serum and human pathogens. L-Fucose can be isolated from the hybridoma cell line by apical chromatography. The analytical method of L-fucose includes body formation, oligosaccharides, and glycan titration calorimetry. Structural analysis of L-fucose includes glycosylation, sugar analysis, and carbohydrate analysis. Fucose can also be used to produce oligosaccharides through enzymatic reactions with other sugars including glucose and galactose. This reaction produces a linkage between fucose and other sugars that are called glycosidic bonds.</p>

<p>L-Menthylglucoside is a custom synthesis, complex carbohydrate. It has CAS number 16203-27-3 and is an Oligosaccharide and Polysaccharide. L-Menthylglucoside has been modified with methylation and glycosylation, which may be due to its Click modification. L-Menthylglucoside is a sugar that is high purity, fluorinated, and synthetic.</p>

<p>Dideoxynojirimycin is a potent hydroxamic acid that inhibits glycosidases. It is used to treat metabolic disorders such as glycogen storage diseases. Dideoxynojirimycin has been shown to inhibit the activity of intestinal maltase, an enzyme involved in the digestion of carbohydrates. This drug also inhibits the synthesis of nucleic acids and proteins, which may be due to its ability to bind nucleophilic groups on enzymes and other biological molecules. The kinetic study showed that 1,6-dideoxynojirimycin has a stereoselective effect on mouse splenocytes, inhibiting their proliferation more effectively than 1,6-dideoxy-N-acetylneuraminic acid.</p>

<p>(2R, 4S) - 3- Fluoro- 2,4- azetidinedimethanol is a fluorinated monosaccharide. It is a synthetic compound that has been modified by methylation and Click chemistry. The fluorination of the sugar allows for high purity and modification of the carbohydrate. This compound is used in the synthesis of oligosaccharides and polysaccharides.</p>

<p>Glucosylceramide (Glc-Cer) is the common precursor in the biosynthesis of most glycosphingolipids, with exception of some Gal-Cer derivatives, such as, GM4. Glucosylceramide consists of a glucosyl moiety which is β-O-glycosydically linked to ceramide, which itself, consists of the long-chain aminoalcohol sphingosine and a fatty acid. Glucosylceramide (also called glucocerebroside) is synthesised enzymatically, by the glucosylceramide synthase-catalysed with the addition of a glucose residue to ceramide. Glucosylceramide is involved in the regulation of various cellular events and also serves as a main constituent in liposome formulations.</p>

<p>(-)-D-Noviose is a naturally occurring sulfoxide that was first isolated from the tubercles of tuberculosis patients. It is a biosynthetic precursor to tiacumicin, an antibacterial agent. In addition, (-)-D-Noviose has been shown to act as a chaperone and inhibit cancer cells in vitro. (-)-D-Noviose binds to the cysteine residues of proteins, preventing their oxidation and subsequent aggregation. This prevents the cross-linking of proteins that leads to cellular damage and death.</p>

<p>1,2,3,4-Tetra-O-benzyl-β-D-glucopyranoside is a prodrug that becomes active after acetylation. It is an endogenous compound that has been shown to inhibit the synthesis of myelin and lipid peroxidation in rat brains. This drug has also been found to be effective in the treatment of amyotrophic lateral sclerosis (ALS). 1,2,3,4-Tetra-O-benzyl-β-D-glucopyranoside is unmodified and does not have any side effects on the nervous system. It can be used for the treatment of Parkinson's disease when combined with levodopa.</p>

<p>1,2-Dideoxy-3,5-di-O-toluoyl-D-ribose is a synthetic sugar that can be used in the synthesis of complex carbohydrates. It has been modified with fluorine, methylation, and click chemistry. It is also available as a high purity product. 1,2-Dideoxy-3,5-di-O-toluoyl-D-ribose is an oligosaccharide that is used in glycosylation reactions to form polysaccharides or saccharides. Click chemistry allows for the modification of this sugar with other molecules such as amino acids or peptides. This modification may be useful for studying protein interactions or for drug development.</p>

<p>UDP-b-L-arabinopyranose is a nucleotide sugar that is used in the synthesis of proteins and other macromolecules. It is synthesized from uridine and d-ribulose 5-phosphate by the enzyme ribulokinase. The reaction between UDP, b-L-arabinofuranose, and ATP, catalyzed by arabinofuranosyl transferase, produces UDP-b-L-arabinopyranose. This nucleotide sugar can be converted to UDP-b-(1→4)-glucuronate by the enzyme glucuronosyltransferase. This process plays an important role in plant physiology as well as in cell wall biosynthesis. The optimal pH for this conversion is 7.5 to 8.2.</p>

<p>1,2,3,4,5-Penta-O-acetyl-β-D-fructose is a synthetic oligosaccharide that is modified with fluorine to produce a variety of products. This product is used in the synthesis of complex carbohydrates and has been shown to have high purity. It is used for methylation reactions and can be found in saccharides and polysaccharides. The CAS number for this compound is 20764-61-8.</p>

<p>D-Glucose 3-sulfate sodium salt is a fluorinated, monosaccharide that can be used as a synthetic, oligosaccharide or complex carbohydrate. It is custom synthesized with glycosylation and polysaccharides and has been shown to be useful in click modification. D-Glucose 3-sulfate sodium salt is also methylated and sugar modified. The CAS number for this product is 89830-83-1. It has high purity and can be purchased at any lab supply store.</p>

<p>Epi-inositol, also known as myo-inositol, is a member of the group of molecules known as sugar alcohols. It is a naturally occurring compound that is found in the human body and can be synthesized by the human body from glucose. Epi-inositol has been shown to have a number of biological effects, including inhibition of cell proliferation and energy metabolism in ovarian cancer cells. Epi-inositol has also been used in clinical trials for treatment of mood disorders such as depression.</p>

<p>The polysaccharide Lentinan is isolated from the mushroom L. edodes (shitake mushroom). The primary structure is a β-(1–3)-glucose backbone with two (1–6)-β-glucose branches for each five glucose resiodues. Lentinan is clinically used for cancer treatment both in China and Japan. According to the clinical studies published in and outside of China, lentinan-based drugs are used for the treatment of various cancers, including lung, gastric, colorectal and other cancers. In addition, lentinan-based drugs are also used for treating HIV, hepatitis and malignant pleural effusion.</p>

<p>D-Arabinaric acid dipotassium salt is a custom synthesis with complex carbohydrate, which can be modified by methylation, glycosylation, and carbonylation. It has CAS number 6703-05-5 and a high purity. This product is also fluorinated, which makes it an excellent synthetic reagent.</p>

<p>Propargyl a-D-glucopyranoside is a high purity custom synthesis sugar. It is synthesized by Click modification, fluorination, and glycosylation followed by methylation. Propargyl a-D-glucopyranoside can be used for the modification of oligosaccharides and monosaccharides to produce complex carbohydrates.</p>

<p>a-D-[UL-13C6]Glucose-1-phosphate dipotassium salt hydrate is a kinetic and structural analysis of the glucose phosphate metabolic pathway. It has been used to study biochemical properties of the glucose phosphate metabolic pathway, and to study the control mechanisms for this process. Specifically, it has been used to determine kinetic parameters that are necessary for understanding glucose metabolism. This compound has also been used to study hydrogen bonding interactions between monoclonal antibodies and ganoderma lucidum and transfer reactions of immobilized enzymes. The pH optimum for this compound is 4.5, and it can be synthesized from solanum tuberosum.</p>

<p>4-Methylphenyl 4,6-O-[bis(1,1-dimethylethyl)silylene]-1-thio-β-D-galactopyranoside is a synthetic sugar that is used in the glycosylation of proteins. It is synthesized from 4-methylphenol and 1,1'-dimethylethylsilylene in the presence of trichlorosilane, followed by silylation with trimethylchlorosilane. The fluorinated site can be modified to suit your needs by following a Click chemistry protocol. This product has CAS No. 1242144-05-3 and is available for custom synthesis upon request.</p>

<p>Methyl 2,3,4,6-tetra-O-benzyl-α-D-glucopyranoside is a benzylated glycoside that inhibits the activity of β-glucosidases and glycoside hydrolases. It is used as an inhibitor in ecological studies to investigate the effects of benzyl groups on biotic and abiotic stressors. Methyl 2,3,4,6-tetra-O-benzyl-α-D-glucopyranoside has been shown to have inhibitory potency against the transition state in enzymatic reactions. This compound also has been shown to be effective in treating diabetes.</p>

<p>1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a modified carbohydrate. It is synthesized by the methylation of 1,3,5-tri-O-benzoyl-a-D-arabinopyranose followed by glycosylation with 3,6-dideoxyhexose. This compound has been used as a substrate in enzymatic studies to investigate the modification of carbohydrates by glycosylation and methylation and can be used for the synthesis of other saccharides.</p>

<p>A toxic glucosamine derivative, widely used for the induction of diabetes in experimental animals. The compound enters the pancreatic β cells in Langerhans islets via glucose transporter GLUT2. It has the ability to alkylate DNA and trigger the production of ROS and nitric oxide, which contribute to DNA and mitochondrial damage. Moreover, streptozocin inhibits N-acetyl-β-D-glucosaminidase and disrupts O-GlcNAc cycling. This molecule has also been used as antimicrobial compound and chemotherapeutic agent for some types of pancreatic cancer.</p>

<p>2,3,5-Tri-O-benzoyl-2-C-methyl-D-ribonic acid-1,4-lactone is a glutamate receptor agonist that has been shown to have pharmacological properties. It binds to the GluR2/3 family of glutamate receptors and is an agonist at these receptors. The experiments with this drug have been conducted on both animals and humans. 2,3,5-Tri-O-benzoyl-2-C-methyl D ribonic acid lactone has also been shown to be an effective probe for the identification of glutamate receptor sequences in the brain and spinal cord.</p>

<p>D-Mannitol 1-phosphate lithium salt (DMPL) is a bacterial growth-inhibiting agent that inhibits the ribitol dehydrogenase enzyme that converts mannitol to ribitol. The wild-type strain of bacteria is more sensitive to DMPL than the mutant strains, which lack this enzyme. This compound has been shown to be active against Aerobacter aerogenes, and it can be used as an antimicrobial agent in plant physiology, where it prevents cell lysis. DMPL is also effective against wild-type strains of E. coli K-12 and has a broad range of pH optima with a maximum at pH 6.0 to 7.0. The reaction mechanism for this drug is not well understood, but it may involve inhibition of the polymerase chain reaction or other enzyme activities.</p>

<p>2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic acid sodium salt is a fatty acid that has been used as an antipsychotic drug. It is the active metabolite of clozapine and has been shown to have similar efficacy to other first generation antipsychotics such as chlorpromazine and haloperidol. 2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic acid sodium salt also has a low energy content and can be audited for its locomotor activity. This drug is a metabolic product of clozapine and has been shown to have similar efficacy to other first generation antipsychotics such as chlorpromazine and haloperidol. 2,3:4,6-Di-O-isopropylidene-2-keto--L--gulonic acid</p>

<p>2-Acetamido-2-deoxy-D-glucopyranose 6-sulphate sodium salt is an Oligosaccharide which is a carbohydrate. It has a CAS No. 108321-79-5 and is available for custom synthesis. 2-Acetamido-2-deoxy-D-glucopyranose 6 sulphate sodium salt can be modified with methylation, saccharide, polysaccharide, click modification, or modification. It can also be glycosylated and fluorinated. The chemical formula of this compound is C6H11NO4SNaO6</p>

<p>Isopropyl 2-acetamido-2-deoxy-α-D-glucopyranoside is a modification of an oligosaccharide. It has been synthesized and characterized by NMR spectroscopy. This carbohydrate is custom synthesized as a complex carbohydrate. It is also a synthetic carbohydrate. Isopropyl 2-acetamido-2-deoxy-α-D-glucopyranoside is used as a monosaccharide, in glycosylation, methylation, polysaccharides, and other sugar chemistry reactions. Isopropyl 2-acetamido-2-deoxy-α-D-glucopyranoside can be used for fluorination or saccharides.</p>

<p>Isosorbide dinitrate is a drug that belongs to the class of nitrates. It is used in the treatment of angina pectoris, as well as congestive heart failure and chronic heart failure. Isosorbide dinitrate has been shown to cause caspase-independent cell death in human leukemia cells and breast cancer cells. This may be due to its ability to inhibit mitochondrial membrane potential and interfere with intracellular calcium mobilization. The optimum concentration for isosorbide dinitrate is 10 µM, which inhibits the growth of bacteria, including Mycobacterium tuberculosis and Salmonella enterica serovar Typhimurium. The drug also inhibits the production of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α by inhibiting c-jun phosphorylation. Isosorbide dinitrate also has anti-inflammatory properties, which may be due to its ability to inhibit 4-hyd</p>