Monossacáridos

<p>D-Mannose-6-phosphate disodium salt hydrate (DMDSP) is an endogenous pentose phosphate metabolite that is found in the human body. DMDSP is generated from the metabolism of mannose and glucose and functions as a regulator of metabolic intermediates. It has also been shown to inhibit bacterial growth and function as a competitive inhibitor of bacterial DNA gyrase, an enzyme that maintains the integrity of bacterial DNA. Genetic polymorphism in the DMDP gene may be associated with changes in response to DMDSP. The reductive amination reaction can be used to synthesize this compound from L-aspartic acid, malic enzyme, and nicotinamide adenine dinucleotide phosphate.</p>

<p>N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. Glycoproteins normally have some level of glycan sialylation, but incomplete sialylation can reduce their therapeutic effect when produced recombinantly. To improve performance, cell lines and culture media can be adjusted. The GNE enzyme controls the efficiency of sialylation in human cell lines, making it crucial for producing effective recombinant glycoprotein drugs. Adding ManNAc and other supplements to culture media improves sialylation, which boosts drug yield, increases stability and half-life, and lowers immune reactions by reducing antibody formation.It has also been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).</p>

<p>2,3,4-Tri-O-acetyl-a-D-xylopyranosyl bromide - Stabilised with 2.5% CaCO3 is a chiral compound that is a drug for the treatment of estrogen deficiency in postmenopausal women. It is synthesized from D-xylose and acetone by reductive elimination using an organotin catalyst. The resulting product has a nitro group at the 4 position and can be activated as a priming agent for DNA synthesis. This compound has been shown to be effective in treating intestinal disorders such as ulcerative colitis.<br>2,3,4-Tri-O-acetyl-a-D-xylopyranosyl bromide - Stabilised with 2.5% CaCO3 has been used to conjugate estrogens with various drugs to create new compounds that are more potent than free estrogens alone. Bioavailability of these conjugates has</p>

<p>1,3,5-Tri-O-benzoyl-2-O-methyl-D-ribofuranose is a modified sugar with three benzoyl groups. It has a molecular weight of 498.18 g/mol and the chemical formula C32H32F6N8O8. The compound is synthesized by the condensation of 2,3,4,5-tetraacetylpyridine with 2,3,4,5-tetraacetylthiophene in the presence of potassium fluoride and sodium hydroxide in aqueous methanol at room temperature. This product is used to study glycosylation reactions and to modify oligosaccharides for research purposes. 1,3,5-Tri-O-benzoyl-2-O-methyl--D--ribofuranose is soluble in water and ethanol but insoluble in ether or chloroform.This product has</p>

<p>Methyl 2,3,4-tri-O-acetyl-6-azido-6-deoxy-a-D-glucopyranoside is a modification of the sugar glucose. It is a synthetically modified oligosaccharide that is used in the synthesis of complex carbohydrates and polysaccharides. Methyl 2,3,4-tri-O-acetyl-6-azido-6-deoxyglucopyranoside has been used for the fluorination and saccharide methylation reactions.</p>

<p>Quinovosamine hydrochloride (QNH) is a fatty acid that belongs to the group of galacturonic acid. It has been shown to be biologically active in wild-type strains and in some bacterial strains, including Pseudomonas aeruginosa. QNH has also been used for preparation of monoclonal antibodies directed against receptor activity, which are activated by QNH.</p>

<p>2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl fluoride is a halide with the chemical formula of F. It has an axial conformation and is a crystalline solid at room temperature. 2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl fluoride reacts with water to form hydrofluoric acid (HF). This compound is an important reagent in carbohydrate analysis because its presence or absence can be used to distinguish between the two anomers of maltose: α-(1→2) and β-(1→4). It also reacts with sodium chloride to give the chloride salt sodium tetrafluoroborate. The molecule has three substituents: a hydroxymethyl group (-OH), a glycosidic oxygen atom (O), and a glucosyl group (-CHO). Watanabe's numbering system for</p>

<p>b-D-Xylopyranosyl azide is a device that records multimedia. It has been found that b-D-Xylopyranosyl azide can record audio, video, and data recordings by automated means. The renaming of multimedia files is also possible with b-D-Xylopyranosyl azide.</p>

<p>Peracetylated 2-fluoro-L-fucose is the acetylated form of 2-deoxy-2-fluoro-L-fucose which is a potent inhibitor of protein fucosylation. It exhibits improved cell permeability and is rapidly deacetylated into its active form, inside the cell. It is metabolised inside the cell into a corresponding donor substrate analogue of GDP-fucose or GDP-2FF, via the salvage pathway. GDP-2FF accumulates in the cell causing a shutdown of de novo pathway which leads to the desired fucosylation inhibition. The addition of 100 uM peracetylated-2-fluoro-L-fucose to plants severely inhibits root growth by 95% compared to an untreated plant, and is more potent compared to 2-fluoro-L-fucose.  The material is soluble in DMSO at 10mg/ml.</p>

<p>4-Methylphenyl 2,3,4,6-tetra-O-acetyl-b-D-thioglucopyranoside is an antibiotic that is used to treat infections caused by a wide range of pathogens. This drug is active against Gram-negative and Gram-positive bacteria, including some resistant strains. 4MPTGA inhibits the growth of bacteria by binding to their ribosomes and preventing protein synthesis. It has been shown to have antimicrobial activity against E. coli and other Enterobacteriaceae species as well as other Gram negative bacteria such as Salmonella typhi and Proteus mirabilis. 4MPTGA has also been shown to be effective against the common animal health pathogen Staphylococcus aureus</p>

<p>1,2-O-Isopropylidene-3-deoxy-3-fluoro-a-D-xylofuranose is a synthetic compound that has been modified by methylation, saccharide and glycosylation. It is a fluorinated sugar that can be used for Click modification, such as for oligosaccharide synthesis or other modifications. 1,2-O-Isopropylidene-3-deoxy-3-fluoro-a-D-xylofuranose is a high purity compound that can be custom synthesized to your specifications. It has CAS No. 1853084 2 and is listed under the Glycosylation section in the Carbohydrate database.</p>

<p>2-(3,4-Dihydroxyphenyl)ethyl b-D-glucopyranoside (2,3,4-DHPEB) is a naturally occurring phenolic acid. It has been shown to have antidepressant activity in mice and rats. 2,3,4-DHPEB inhibits the growth of Streptococcus faecalis by inhibiting fatty acid biosynthesis. This compound also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. 2,3,4-DHPEB is a ligand for PPAR receptors and activates their transcriptional activity in cells. It has been shown to have chemopreventive effects against colon cancer cell lines and is able to induce apoptosis in tumor cells.</p>

<p>L-Lyxono-1,4-lactone is a dehydrogenase that synthesizes hydroxamic acids from aldonic acids. Hydroxamic acids are used as herbicides and insecticides. L-Lyxono-1,4-lactone has been shown to be active against ochrobactrum and branched-chain bacteria. The enzyme catalyzes the cleavage of an aldonic acid to form an alcohol and an alpha,beta unsaturated ketone. This reaction is stereoselective, with the product being the same chiral center in both cases. The enzyme also shows chemometric properties by being able to measure salinity levels in water samples.</p>

<p>N-Acetyl-L-xylosamine is a custom synthesis of a glycosylation product that contains an acetyl group and a xylosamine. It is used as a building block for the synthesis of complex carbohydrates. N-Acetyl-L-xylosamine can be modified with fluorination, saccharide, modification, sugar, or oligosaccharide to create custom products.</p>

<p>1,2,3-Tri-O-acetyl-4,6-O-benzylidene-b-D-galactopyranose is a high purity and custom synthesis sugar. This product has been modified with fluorination, glycosylation, methylation, and modifications. It is also known by the CAS number 78962-43-3. 1,2,3-Tri-O-acetyl-4,6-O-benzylidene b -D -galactopyranose is an oligosaccharide that can be used as a monosaccharide or saccharide. It is a complex carbohydrate that has many uses in the food industry.</p>

<p>This is a Custom Synthesis of a 1,2,4,6-Tetra-O-acetyl-3-O-benzyl-D-glucopyranose. The desired product is an Oligosaccharide with a complex carbohydrate structure. It has been Fluorinated and Methylated in order to create the desired product. Modification and Click Modification have also been performed on this molecule.</p>

<p>Important resource for RNA- and DNA-related syntheses including ribosylation</p>

<p>Calcium lactate gluconate is an antacid and a calcium supplement. It is a salt of calcium with lactic acid, which is often used to treat or prevent kidney stones and periodontal disease. Calcium lactate gluconate also helps to form new bone by stimulating osteoblasts, the cells responsible for bone formation. This drug can be used therapeutically to increase bone growth in people with osteoporosis or to repair bones after injury. It also helps heal fractures, relieves pain from arthritis, and treats cancer by preventing cell proliferation. Calcium lactate gluconate is a white powder that dissolves in water and can be mixed with other liquids such as fruit juice or milk.</p>

<p>2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl amine is an artificial carbohydrate with a fluorinated sugar. It is synthesized by reacting 2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl chloride with ammonia and methyl iodide. The compound can be used to modify the sugar residues of glycosides or polysaccharides. It has been shown to have high purity and can be used in the synthesis of complex carbohydrates.</p>

<p>Benzyl 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-a-D-mannopyanoside is a modification of an oligosaccharide. It is a complex carbohydrate that has been synthesized from a monosaccharide and methylated on the 3' hydroxyl group. This product is available as a custom synthesis and is offered in high purity. The CAS number for this compound is 1423035-45-3.<br>br&gt;<br>Benzyl 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-a-D-mannopyanoside can be used as a sugar or fluorinated saccharide in glycosylation reactions with other molecules. It can also be used to produce polysaccharides by glycosylation with other molecules such as glucose, mannose, or sucrose.</p>

<p>Decyl Glucoside is an alkylglycoside non-ionic surfactant and emulsifier. It is commonly used in foaming and cleansing products, often by natural personal care companies due to being plant derived and biodegradable. Decyl glucoside, also known as capryl/caprylyl glucoside, is derived from combination of coconut fatty alcohols and corn starch glucose.</p>

<p>Methyl-2,3,4-tri-O-benzoyl-6-bromo-6-deoxy-alpha-D-glucopyranoside is a sugar that belongs to the group of monosaccharides. It is a custom synthesis product that can be synthesized and modified according to customer's requirements. Methylation, fluorination and saccharide modification are possible and highly pure methylated products can be produced with high purity.</p>

<p>Arabinonic acid potassium salt is a fluorinated monosaccharide that is used as a building block for the synthesis of oligosaccharides and polysaccharides. Arabinonic acid potassium salt is chemically synthesized by the glycosylation of 2-deoxy-D-ribose with arabinonitrile followed by hydrolysis to form arabinonic acid. This chemical can also be modified with methyl groups, nitro groups, or other functional groups. It has CAS number 36232-89-0 and molecular weight of 176.17 g/mol. Arabinonic acid potassium salt is a high purity product with 98% minimum purity and no detectable impurities.</p>

<p>Short-term marker of glycemic control</p>

<p>L-Mannitol is a sugar alcohol that is an important component of pharmaceutical preparations. It is used as a preservative, diluent, and sweetener in many pharmaceutical products. L-Mannitol has been shown to have anti-inflammatory properties and may help prevent allergic reactions by inhibiting the production of prostaglandin D2. L-Mannitol also inhibits the activity of xylitol dehydrogenase, which prevents the conversion of xylitol to DHA, an intermediate metabolite that can cause tissue damage in animals and humans. L-Mannitol has been shown to have a laxative effect when taken orally or injected as an intravenous solution. This property may be due to its ability to stimulate chloride secretion from intestinal cells and increase water reabsorption from the colon. L-Mannitol is also used as a chromatographic matrix for saponins and conjugates with other amino acids.</p>

<p>Inhibitor of β-glucuronidase enzyme; prevents cleavage of glucuronides.</p>

<p>2,3,5-Tri-O-benzyl-D-xylonic acid-1,4-lactone is a complex carbohydrate that has been synthesized from saccharides. This compound is fluorinated and methylated at the 2, 3, and 5 positions of the xylan backbone. The lactone ring has been modified with a click chemistry reaction to introduce an alkyne group for glycosylation. This product can be custom synthesized to include any modification of your choice.</p>

<p>D-Glucuronic acid 3-phenylpropyl ester is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide, Polysaccharide, Modification, saccharide with Methylation and Glycosylation modifications. It has a molecular weight of 785.32 g/mol and purity of 99%. D-Glucuronic acid 3-phenylpropyl ester is Fluorinated at the hydroxyl group on the C2 carbon atom. It has been shown to be effective in inhibiting the proliferation of vascular smooth muscle cells and cancer cells through modification of protein synthesis.</p>

<p>This product is a custom synthesis. The chemical formula for this product is C8H11N2O4. This product has the molecular weight of 272.24 g/mol and the molecular formula is C8H11N2O4. This product is synthesized from 3-acetamido-1-benzylazetidine-2R,4S-diyl bis(methylene) diacetate monohydrate. It can be fluorinated, glycosylated, methylated, modified and oligosaccharide or monosaccharide saccharides. This product can be used in various fields such as pharmaceuticals, agrochemicals, food additives, cosmetics and so on.</p>

<p>6-Azido-6-deoxy-D-fructose is a piperidine that condenses with glyceraldehyde in the presence of aldolase and produces D-glyceraldehyde. This reaction is stereospecifically catalyzed by aldolase, which converts the product to D-glyceraldehyde 3-phosphate. 6Azido-6deoxy-D-fructose has been shown to exhibit polyhydroxylated properties.</p>

<p>A partially methylated glucose with the anomeric position free</p>

<p>1,2,3,4-Tetra-O-acetyl-b-D-glucuronide is a chemical compound that is used as an acetylating agent in organic synthesis. It is produced by the reaction of pyridine and acetic anhydride with sodium hydroxide as a catalyst. The acetylation process takes place in two steps: first, the pyridine reacts with the acetic anhydride to form 4-(pyridinium) acetate; second, this intermediate reacts with sodium hydroxide to form 1,2,3,4-tetra-O-acetyl-b-D-glucuronide. Acetylation reactions are important because they can be used to introduce functional groups onto molecules that would not otherwise have them. Acetylated compounds are also often more soluble in water than nonacetylated compounds. This product is used in medicines and other chemical processes.</p>

<p>Methyl 3,4:5,6-di-O-isopropylidene-D-gluconate is a modification of the oligosaccharide, carbohydrate. It is a complex carbohydrate that has been custom synthesized and is available in high purity. This product can be used as a monosaccharide or as a methylated glycosylated saccharide. Methyl 3,4:5,6-di-O-isopropylidene-D-gluconate can be found under CAS No. 114743-85-0 and has the molecular formula C12H22O11.</p>

<p>2-Deoxy-2-fluoro-b-D-glucopyranosyl azide is a fluorinated carbohydrate that can be used for custom synthesis of saccharides and polysaccharides. It is a methylated derivative of 2,3,4,6-tetrafluorobenzoyl azide which can be used to synthesize glycosylations using an oxazaborolidine (e.g., BOP) activation method or click modification. The compound has been shown to react with glycosylations in the presence of copper ions.</p>

<p>A gallotannin found in plants, with various biological activities. Its anti-cancer effect has been demonstrated in several cancer cell lines, mediated by inhibition of DNA replication, proliferation and angiogenesis. Elicits anti-inflammatory, antioxidative and anti-diabetic effects. Recently, it has been identified as an inhibitor of c-Myc in hepatocellular carcinoma and multiple myeloma cells.</p>

<p>Building block for the 6-O-modification of Glc, including 6-O-glycosylations</p>

<p>Hexahydro-1,2,8-trihydroxy-[1S-(1a,2a,8a,8ab)]-5(1H)-indolizinone is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide and Polysaccharide. The saccharide Methylation and Glycosylation are the Modification of this molecule. This product has CAS No. 96625-36-4 and Click modification is Carbohydrate sugar. This product is highly pure with Fluorination Synthetic</p>

<p>Glucose 6-phosphatase substrate</p>

<p>1-Octylamino-1-deoxy-D-glucitol is a natural product that is extracted from the bark of the tree Streptomyces griseorubens. It has been shown to have a diastereomeric ratio of 97:3 and an optical purity of 98%. The thermodynamic properties of this compound are determined by the reaction time, which can vary from 1 to 24 hours. The enantiomers are separated by chromatography or crystallization, and the solubility data is determined at 25°C.</p>

<p>Low-calorie sweetener; additive in detergents, cosmetics, and pharmaceuticals</p>

<p>3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl fluoride is a synthetic glycoside that has been synthesized by the click modification of a fluorinated saccharide. The compound has an acetyl group at C3 and C6 positions with an OCH3 group at the C4 position. This compound has been used in glycosylation reactions to modify the carbohydrate moiety of peptides and proteins. It has also been used in research on complex carbohydrate chemistry.</p>

<p>Intermediate for the anomeric modification of Fuc, including fucosylation</p>

<p>Starting material for chiral-pool based synthesis of modified nucleosides</p>

<p>1,3,4,6-Tetra-O-acetyl-a-D-glucopyranose is a synthon that is used as a synthetic intermediate for the synthesis of other compounds. It is also a reactive compound that can be used to synthesize carboxylic acids and hydroxy ketones by reaction with water or alcohols. 1,3,4,6-Tetra-O-acetyl-a-D-glucopyranose can also be converted into esters by reaction with alcohols.</p>

<p>4-Acetamidophenyl b-D-glucuronide sodium salt is a pharmaceutical drug that is a metabolite of acetaminophen. It can be detected in the urine by biochips, which are microarrays that contain immobilized binding sites for specific analytes. The analysis of 4-acetamidophenyl b-D-glucuronide sodium salt in urine is used to screen for the use of acetaminophen and to identify cytochrome P450 2C19 (CYP2C19) activity. This drug can also be detected by spectrometric methods using biochemical assays on plates or hepatocytes and mass spectrometric detection methods using liquid chromatography/mass spectrometry (LC/MS). Acetaminophen has been shown to have toxic effects on the liver, kidneys, and lungs in humans, as well as on diode photoluminescence.</p>

<p>Propyl b-D-glucuronide is a synthetic compound that belongs to the family of carbohydrates. It has a fluorinated hydroxyl group at the C3 position and an esterified carboxylic acid at the C1 position. This compound can be used as a building block for oligosaccharides and polysaccharides, which are complex carbohydrates. Propyl b-D-glucuronide is soluble in water and has a molecular weight of 176.</p>

<p>Resource for the synthesis of Clofarabine and other bioactive arabinosides</p>

<p>L-Rhamnose diethyl mercaptal is an antiperspirant and deodorant that is used in combination with other ingredients to reduce or eliminate body odor. It is a supplement, often found in combinations with other compounds such as neodymium and radium. This compound works by preventing the formation of sweat from the apocrine glands, which reduces underarm wetness and body odor. L-Rhamnose diethyl mercaptal also has antimicrobial properties that help prevent bacterial growth on the skin surface.</p>

<p>1,2,3,4-Tetra-O-benzoyl-6-O-tert-butyldiphenylsilyl-b-D-galactopyranose is a modified oligosaccharide that is synthesized and offered at high purity. The chemical name of this compound is 1,2,3,4 tetra O benzoyl 6 O tert butyldiphenylsilyl b D galactopyranose. This compound is fluorinated at the 2 position of the sugar molecule with a silyl group on the 3 position. It has CAS number 1222709-87 6.</p>

<p>2-Deoxy-2-fluoro-D-galactose, also called 3-fluoro-6-hydroxymethyl-tetrahydro-pyran-2,4,5-triol, can be added to the medium of primary cultured rat hepatocytes to inhibit N-glycosylation of proteins. Immunoglobulin G (IgG) is the most common antibody found in blood and 2-deoxy-2-fluoro-D-galactose modifies the galactosylation of the N-linked glycan in the IgG-Fc receptor.  We also have this product from a non-animal origin, MD71984.</p>