Monossacáridos

<p>Suberoylanilide hydroxamic acid b-D-glucuronide (SAHA) is a histone deacetylase inhibitor that is used in the treatment of colorectal adenocarcinoma. It is orally administered and can cross the blood-brain barrier to inhibit HDACs in human liver cells. SAHA has been shown to be effective against a number of cancer cell lines, including colon, prostate, breast, lung, and leukemia cell lines. SAHA has also been shown to have clinical benefits in various cancers and has been found to be safe at doses up to 1g/day when given for 24 months. The most common side effects are thrombocytopenia and anorexia.</p>

<p>alpha/beta mixture - ratio of mixture can be variable</p>

<p>N-Acetyl-D-[U-13C6,15N]glucosamine is a custom synthesis of an oligosaccharide. It is a methylated form of glucosamine and has been modified with 13C 6, 15N atoms. N-Acetyl-D-[U-13C6,15N]glucosamine is used in the study of complex carbohydrate structures and can be used for the production of polysaccharides. This chemical contains a single monosaccharide sugar that can be easily modified with fluorine to produce complex carbohydrates for research purposes. The purity level of this chemical is greater than 99%.</p>

<p>Methyl 2-deoxy-2-fluoro-b-D-glucopyranoside is a synthetic glycosylation product that is prepared by monosaccharide and polysaccharide modification. This fluorinated sugar has high purity and is easy to handle. It can be used in the synthesis of oligosaccharides, sugar chains, and other complex carbohydrate molecules. The CAS number for Methyl 2-deoxy-2-fluoro-b-D-glucopyranoside is 39110–58–2.</p>

<p>1,3,5-Tri-O-benzoyl-2-keto-a-D-ribofuranose (TOBR) is a high purity compound that can be custom synthesized to your specifications. The 1,3,5-trioxane ring is an important structural feature of TOBR. This modification has been shown to improve the stability and water solubility of the product. TOBR is an Oligosaccharide with a sugar or saccharide at the end of a Glycosylation chain. It is also classified as a Polysaccharide because it contains more than one saccharide unit and/or more than one type of sugar. To modify this product with Click chemistry, please contact us and we will send you instructions on how to proceed with this modification.</p>

<p>6-Deoxy-D-gulose is a non-metabolizable sugar molecule that is used by bacteria to synthesize the acetonides, which are used as antibiotics. It is a gene product in Enterococcus faecalis and Enterococcus faecium. 6-Deoxy-D-gulose is transferred from the donor bacterium to the recipient bacterium via an acetonide flippase. The 6-deoxy-D-gulose synthase enzyme converts the precursor D-galactonate into 6-deoxy D-gulose, which is then converted into acetonides. This process occurs in gram negative bacteria such as E. coli K12 and Salmonella enterica serovar Typhimurium.</p>

<p>Blumenol C glucoside is a natural compound that is found in plants. It has been found to have an apoptotic effect on cancer cells and may be used as a chemotherapeutic agent. Blumenol C glucoside has been shown to induce apoptosis in many cell types, including human carcinoma cells, by inhibiting the mitochondrial membrane potential. It also induces apoptosis by down-regulating Bcl-2 and up-regulating Bax proteins. The induction of apoptosis by Blumenol C glucoside is mediated through an increase in the release of cytochrome c from the mitochondria into the cytosol. In addition, it inhibits the expression of proinflammatory cytokines such as IL-1β and IL-6. This compound also induces apoptosis in normal human prostate epithelial cells and mouse colon epithelial cells without affecting normal human lung epithelial cells or mouse lung epithelial cells. A transcriptomic analysis revealed that Blumenol</p>

<p>2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone is a farnesyltransferase inhibitor that belongs to the group of techniques. It is used in the diagnosis of relapsed and resistant multiple myeloma. This drug has been shown to be a potent inductor of apoptosis in vitro and in vivo through inhibition of protein synthesis. 2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone also inhibits the growth of tumor cells and can be used as a potential chemotherapeutic agent for pediatric patients with relapsed or resistant myeloma.</p>

<p>Ammonium 8-azido-3,8-dideoxy-D-manno-octulosonate is an oligosaccharide that is a modification of the natural polysaccharide mannoheptulose. It has been shown to be highly soluble in water and can be easily synthesized. Ammonium 8-azido-3,8-dideoxy-D-manno-octulosonate has been shown to inhibit the activity of glycosyltransferases and methyltransferases. This compound also has a high degree of purity, with minimal impurities or degradation products.</p>

<p>D-Glycero-D-talo-heptose is a fluorescent probe used in fluorescence spectroscopy. It has been shown to bind to mannose and lyxose, which are carbohydrates with a structural similarity to D-glycero-D-manno-heptose. D-Glycero-D-talo-heptose undergoes dose dependent emission of light when excited at 488 nm. In addition, this compound can be used as a marker for liquid chromatography. The fluorescence of D -glycero -D -talo -heptose is quenched by the presence of ribose.</p>

<p>The utilization of D-Erythrose 4-phosphate extends to various research applications, particularly in studying metabolic pathways and enzyme catalysis relevant to both prokaryotic and eukaryotic organisms.</p>

<p>6-O-Hydroxyethyl-D-glucose (6OHEDG) is a homologue of glucose that has been synthesized by reacting paraformaldehyde with ethylene in the presence of a glucofuranose. It is used as a solute for uptake studies, hydrolyzates for ion-exchanges, and glucoses for preparative chromatographic techniques. 6OHEDG is also used as an analog to glucose in polyethylene glycols and anhydroglucoses.</p>

<p>1,2:4,5-Di-O-isopropylidene-b-D-erythro-2,3-hexodiulo-2,6-pyranose is an acidic compound that is a constituent of the ginseng plant. It has been shown to have biochemical properties as well as bioactivities. It can be synthesized in vivo from the amino acid L-lysine by the enzyme diammonium glyoxalate reductase. The compound has two chiral centers and four stereogenic centers. It is a trisubstituted diastereomer with oxygenated ring opening and chemical structures consisting of a pyranose ring and an ethylene glycol moiety.</p>

<p>Salacinol is a naturally occurring sulfonium ion, which is a bioactive compound found primarily in the roots and stems of the plant Salacia reticulata. This plant is native to regions of South Asia, particularly India and Sri Lanka, and is traditionally used in Ayurvedic medicine. Salacinol's mode of action involves the inhibition of alpha-glucosidase, an enzyme responsible for breaking down carbohydrates into glucose. By inhibiting this enzyme, salacinol reduces the postprandial rise in blood glucose levels, thus demonstrating antidiabetic potential.</p>

<p>GDP-6-deoxy-a-D-talose is a synthetic oligosaccharide that can be modified to include fluorine, methylation, or other modifications. It has been synthesized for use in the modification of saccharides and complex carbohydrates. GDP-6-deoxy-a-D-talose is soluble in water and has a molecular weight of 519.</p>

<p>2-Acetamido-6-azido-2,6-dideoxy-D-glucopyranose is a synthetic compound with an azide functional handle, so set up for click chemistry</p>

<p>2-Acetamido-2-deoxy-b-D-glucopyranosylnitromethane is a natural product that can be found in the extract of gladiolus. It has been shown to have antimalarial activity against Plasmodium falciparum and other species. 2-Acetamido-2-deoxy-b-D-glucopyranosylnitromethane inhibits the growth of bacteria by binding to the 50S ribosomal subunit, preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.</p>

<p>(-)-2,3-O-Isopropylidene-D-threitol is a chiral compound with two stereoisomers. It is a crystalline solid that melts at 71°C and has a population of 50%. (-)-2,3-O-Isopropylidene-D-threitol is an important intermediate for the synthesis of polyethers with chiral centers. The catalytic asymmetric synthesis of (-)-2,3-O-isopropylidene-D-threitol is achieved by alkylation of (+)-2,3-(dimethoxyphosphinyl)propane with isopropanol. This reaction can be used to produce polyethers with chiral centers in high yields and enantioselectivity.</p>

<p>cis-Zeatin-o-glucoside is a naturally occurring cytokinin glycoside, which is a derivative of cis-zeatin conjugated with a glucose molecule. It is synthesized in various plant tissues and acts as an important signaling compound within the plant's hormonal network. The mode of action involves the regulation of cell division and differentiation, primarily through modulating the expression of specific genes and interacting with cytokinin receptors. This glycosylation potentially alters the transport, stability, and activity of the cytokinin, influencing its overall biological effect.</p>

<p>1,2,3,4,6-Penta-O-acetyl-5-thio-D-glucose is a synthetic sugar that can be used as a building block in the synthesis of glycosides and oligosaccharides.</p>