APIs per la ricerca e le impurità
Subcategorias de "APIs per la ricerca e le impurità"
- Aminoacidi e Derivati(12.348 produtos)
- Antrachinoni e Derivati(405 produtos)
- Derivati del Benzimidazolo e dell’Imidazolo(10.463 produtos)
- Derivati delle Benzodiazepine(335 produtos)
- Carboidrati e Glicoconiugati(5.048 produtos)
- Esteri e Derivati(42.305 produtos)
- Acidi Grassi e Derivati Lipidici(32.454 produtos)
- Flavonoidi e Polifenoli(17.098 produtos)
- Radicali Liberi e Agenti Ossidanti/Riducenti(214 produtos)
- Chetoni e Derivati(2.402 produtos)
- Antibiotici Naturali e Semisintetici(6.398 produtos)
- Nitrili e Derivati Ciano(3.070 produtos)
- Nitrosammine e Derivati(55 produtos)
- Nucleosidi e Nucleotidi(3.486 produtos)
- Fosfati e Fosfonati Organici(1.202 produtos)
- Solfonati e Solfati Organici(10.447 produtos)
- Composti Organometallici(4.424 produtos)
- Altri(6.322 produtos)
- Peptidi e Proteine(3.151 produtos)
- Polimeri e Derivati(100 produtos)
- Derivati delle Purine e Pirimidine(8.957 produtos)
- Derivati della Chinazolina e Chinolina(66.131 produtos)
- Chinoni e Derivati(24.376 produtos)
- Sali e Derivati degli API(80.360 produtos)
- Steroidi e Derivati(4.975 produtos)
- Sulfonamidi e Derivati(2.606 produtos)
- Terpenoidi e Derivati(3.858 produtos)
- Tiazolidinedioni e Tiopirani(2.755 produtos)
- Composti β-Adrenergic(231 produtos)
Foram encontrados 57677 produtos de "APIs per la ricerca e le impurità"
N-Carboxylate-6-hydroxy melatonin ethyl ester
CAS:Please enquire for more information about N-Carboxylate-6-hydroxy melatonin ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C16H20N2O5Pureza:Min. 95%Peso molecular:320.34 g/molRef: 3D-RFC05208
Produto descontinuadoCiprofibrate-o-β-glucuronide
CAS:Ciprofibrate-o-β-glucuronide is the major metabolite of ciprofibrate in humans. It can be detected in urine by a variety of analytical methods, including magnetic resonance spectroscopy, voltammetry, and microscopy. Ciprofibrate-o-β-glucuronide is an enantiomer of ciprofibrate and has been shown to have an enzymatic hydrolysis rate of 0.07% per hour. This hydrolysis process is catalyzed by cytochrome P450 enzymes. Ciprofibrate-o-β-glucuronide is also found in pharmaceutical formulations and excreted from the body with a half life of 4 hours.
Fórmula:C19H22Cl2O9Pureza:Min. 95%Peso molecular:465.3 g/molRef: 3D-CEA62315
Produto descontinuadotert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate
CAS:tert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate is an impurity that is found in the production of tert-butyl 4-(4,5,6,7,8,9,10-hexahydrobenzo[a]pyrido[1,2:4,3]triazin-2(3H)-yl)piperazine-1 carboxylate. It has been used as a reference standard for HPLC. This compound is not active when administered orally and does not exhibit any pharmacological activity.Fórmula:C19H27N5O4Pureza:Min. 95%Peso molecular:389.4 g/molRef: 3D-KAC93966
Produto descontinuado(9Z)-Roxithromycin
CAS:Roxithromycin is a macrolide antibiotic that inhibits protein synthesis in bacteria. It binds to the 50S ribosomal subunit, thereby inhibiting bacterial growth. Roxithromycin has been used to diagnose intestinal and esophageal diseases, inflammatory diseases, and cancer. There are some cardiac effects associated with Roxithromycin that may be related to its ability to inhibit serotonin reuptake. This drug also has anti-inflammatory properties and has been shown to be effective against influenza virus infections as well as other infectious diseases such as tuberculosis and HIV/AIDS.
Fórmula:C41H76N2O15Pureza:Min. 95%Peso molecular:837.05 g/molRef: 3D-IR106421
Produto descontinuadoTetracosanoic-d47 acid
CAS:Produto ControladoTetracosanoic acid is a drug product that is used in the development of drugs and as an analytical standard. Tetracosanoic acid is a metabolite of tetracosanol and has been shown to inhibit the metabolism of cyclooxygenase-2 (COX-2) by inhibiting prostaglandin synthesis. Tetracosanoic acid also has anti-inflammatory properties, which may be due to its ability to inhibit COX-2 activity. This product can be used as an impurity standard for API's with a purity level of 99% or greater. Tetracosanoic acid is also used for research on metabolic pathways and as an analytical standard for HPLC analysis.
Fórmula:C24HD47O2Pureza:Min. 95%Peso molecular:415.93 g/molRef: 3D-TCA06000
Produto descontinuado1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride
CAS:1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride is a drug product that is not yet approved for use in humans. It is an impurity found in the drug cyclosporine, which is used to treat psoriasis and other skin conditions. 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride has been shown to be inactive in the metabolism studies of rats and dogs. This impurity was detected by HPLC with UV detection at 254 nm, but it did not show any significant absorption at 280 nm. The purity of this compound was determined to be 97% by NMR analysis and HPLC.
Fórmula:C16H25NO2·HClPureza:Min. 95%Peso molecular:299.84 g/molRef: 3D-IM63866
Produto descontinuadoEsomeprazole Impurity Q
Esomeprazole Impurity Q is a drug product. It is an impurity standard of esomeprazole, CAS No. 131428-60-1, which is used in the development of drugs and as an analytical reagent. It is synthesized from natural materials and has a purity of 99%. The metabolite can be found in animal and human metabolism studies. Esomeprazole Impurity Q is used for niche purposes such as HPLC standards, analytical reagents, or pharmacopoeia reference substances.
Pureza:Min. 95%Albendazole impurity F
CAS:Albendazole is an anti-helminthic drug that is structurally classified as a benzimidazole. It has been shown to be effective against a variety of helminths, including roundworms, pinworms, hookworms, and tapeworms. Albendazole impurity F is an analytical standard for the determination of albendazole in pharmaceutical products by HPLC. It also serves as a reference substance to establish the purity of drug products containing albendazole and its metabolites. Albendazole impurity F is not considered to be a metabolite of albendazole because it has been shown to be stable under acidic conditions and can be synthesized from other starting materials.
Fórmula:C10H11N3O2SPureza:Min. 95%Peso molecular:237.28 g/molRef: 3D-IA71873
Produto descontinuadoRegorafenib metabolite M2 oxide
CAS:Regorafenib metabolite M2 oxide (M2O) is a cancer drug that is an inhibitor of multikinase. It was developed as a prodrug for regorafenib, which is used to treat patients with metastatic colorectal cancer and has been shown to be effective against other cancers, such as lung and pancreatic cancer. M2O inhibits the efflux of drugs from cells by binding to the transporter protein P-glycoprotein. This prevents the accumulation of toxic concentrations of regorafenib in cells, which are responsible for its side effects, such as diarrhea and liver damage. The uptake of M2O by cells is also inhibited by light and acidic conditions. Oral administration of M2O leads to increased exposure to regorafenib in the body because it is not metabolized by CYP3A4 enzymes.
Fórmula:C21H15ClF4N4O4Pureza:Min. 95%Peso molecular:498.81 g/molRef: 3D-IR164114
Produto descontinuadoN-Acetyl N-descarboxyethyl retigabine d4
CAS:N-Acetyl N-descarboxyethyl retigabine (D4) is a pharmaceutical drug that is used for the treatment of epilepsy. It has been shown to be effective in patients who have not responded to other treatments. D4 binds to voltage-gated potassium channels and inhibits their opening, which leads to a decrease in neurotransmitter release from nerve cells. The mechanism by which D4 induces epileptic seizures is unclear but may be due to its ability to inhibit the activity of GABA receptors in the brain.Fórmula:C15H16FN3OPureza:Min. 95%Peso molecular:273.3 g/molRef: 3D-EJA97068
Produto descontinuadoLysolecithin
CAS:Lysolecithin is an analog of the phospholipid lecithin that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in cell signaling and regulation. Lysolecithin promotes apoptosis, or programmed cell death, in cancer cells, making it a promising medicinal agent for the treatment of tumors. Studies have also shown that lysolecithin can inhibit protein kinase activity in human urine and inhibit the growth of cancer cells in Chinese hamsters. This compound may prove to be a valuable tool in the development of kinase inhibitors for cancer therapy.
Fórmula:C24H50NO7PPureza:Min. 95%Peso molecular:495.6 g/molRef: 3D-PAA86327
Produto descontinuadoDeschloro-zopiclone
CAS:Deschloro-zopiclone is a drug product that is custom synthesized for research and development purposes. It is a synthetic drug that has been shown to have pharmacological properties in the treatment of insomnia. Deschloro-zopiclone is metabolized by hydrolysis, oxidation and conjugation, with the major metabolites being 2,5-dimethoxybenzoic acid and 2-hydroxy-5-methoxybenzoic acid. The metabolite 2,5-dimethoxybenzoic acid has been shown to be responsible for the hypnotic effects of deschloro-zopiclone.
Fórmula:C17H18N6O3Pureza:Min. 95%Peso molecular:354.4 g/molRef: 3D-YDC04661
Produto descontinuadoMonobenzyl fosaprepitant
CAS:Monobenzyl fosaprepitant is a drug product that is used for research and development purposes. It is an impurity standard for the analysis of API (Active Pharmaceutical Ingredient) impurities, which are synthetic products. Monobenzyl fosaprepitant has been shown to be metabolized in vitro. The metabolism studies have shown that this compound can be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid. Monobenzyl fosaprepitant is a high-purity analytical standard and is used as a pharmacopoeia monograph material.
Fórmula:C30H28F7N4O6PPureza:Min. 95%Peso molecular:704.50 g/molRef: 3D-PKB85202
Produto descontinuado(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2-methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid sodium salt
CAS:(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2-methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid sodium salt is a synthetic drug product. It is an impurity standard in the synthesis of Metabolism studies. The CAS number is 1714147-50-8 and the chemical name is (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2 methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5dihydroxyheptenoic acid sodium salt. The molecular weight is 781
Fórmula:C25H33FN3NaO7SPureza:Min. 95%Peso molecular:561.6 g/molRef: 3D-IF156830
Produto descontinuadoPalbociclib Impurity F
CAS:Palbociclib Impurity F is a high purity synthetic intermediate for the production of Palbociclib. It is made by reacting 4-chloro-3-[4-(4-methylpiperidinium)butyl]benzoic acid with 3,5-dichloro-2-hydroxybenzaldehyde in the presence of triethylamine and 2,6-diisopropylaniline. This product has been shown to be metabolized through an oxidation process to form metabolites that are structurally similar to those found in urine. The chemical structure of this impurity can be found in CAS No. 851067-56-6.
Fórmula:C22H26BrN7OPureza:Min. 95%Peso molecular:484.4 g/molRemdesivir impurity 3 HCl
CAS:Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0
Fórmula:C9H19NO2·HClPureza:Min. 95%Peso molecular:209.71 g/mol[1-Hydroxy-3-(methylisopentylamino)propylidene] bisphosphonic acid monosodium (ibandronic acid impurity)
CAS:[1-Hydroxy-3-(methylisopentylamino)propylidene] bisphosphonic acid monosodium (ibandronic acid impurity) is a metabolite of ibandronate, which is used in the treatment of osteoporosis. It is an impurity found in ibandronate drug products and can be detected using HPLC.
Fórmula:C9H22NNaO7P2Pureza:Min. 95%Peso molecular:341.21 g/molDoxorubicin Impurity 15
CAS:Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.
Fórmula:C31H38BrNO11Pureza:Min. 95%Peso molecular:680.54 g/molRef: 3D-ID163220
Produto descontinuadoTiotropium EP Impurity I
CAS:Tiotropium EP Impurity I is an impurity found in the API, Tiotropium EP. It is a natural product that is synthesized by chemical synthesis. The synthetic purity of Tiotropium EP Impurity I is high and complies with pharmacopoeia guidelines. This impurity can be used as a standard to test the quality of other products or to research the metabolism of Tiotropium EP.
Fórmula:C19H22BrNO4S2Pureza:Min. 95%Peso molecular:472.40 g/molRef: 3D-LFA52148
Produto descontinuadoo-Desphenyl sofosbuvir
CAS:o-Desphenyl sofosbuvir is a drug product that has been custom synthesized for research purposes. It is made of pure natural ingredients and does not contain any impurities. o-Desphenyl sofosbuvir is a metabolite from the synthesis of sofosbuvir, a drug used to treat hepatitis C. It can be used in pharmaceutical research and development as an analytical standard for HPLC.
Fórmula:C16H25FN3O9PPureza:Min. 95%Peso molecular:453.36 g/molN-Trityl candesartan ethyl ester
CAS:N-Trityl candesartan ethyl ester is a drug product that has been custom synthesized for research and development purposes. It is an impurity standard for the synthesis of metoprolol. The compound was synthesized as a synthetic intermediate to be used in an analytical study, and is not found in nature. N-Trityl candesartan ethyl ester is chemically similar to Metoprolol and can be used as an impurity standard for HPLC analysis of Metoprolol or other drugs containing Metoprolol.
Fórmula:C45H38N6O3Pureza:Min. 95%Peso molecular:710.80 g/molRef: 3D-XWC98581
Produto descontinuado(+)-Cis-phenothrin
CAS:Cis-phenothrin is a carbamate insecticide that is used in agriculture, public health, and veterinary medicine. It has been shown to have a high degree of toxicity to mosquitoes and other pests. Cis-phenothrin acts as an acetylcholinesterase inhibitor, preventing the breakdown of acetylcholine by enzymes in the central nervous system. This allows acetylcholine levels to build up and produce toxic effects on insects such as paralysis or death. Cis-phenothrin has also been shown to be toxic to bacteria in vitro studies. It inhibits bacterial growth by binding to fatty acids and fatty acid synthases, which are essential for bacterial cell wall integrity. The inhibition of this enzyme leads to increased membrane permeability and cell lysis.
Fórmula:C23H26O3Pureza:Min. 95%Peso molecular:350.4 g/molRef: 3D-BCA18688
Produto descontinuado(4-Chlorophenyl)[4-(1-methylethoxy)phenyl]methanone
CAS:(4-Chlorophenyl)[4-(1-methylethoxy)phenyl]methanone is a drug product that is Custom synthesized to meet the requirements of pharmacopoeia, analytical, and drug development. It has been studied for its metabolism and toxicity profile in animals. This compound is a metabolite of chlorpheniramine, which is used as an antihistamine. Metabolites of this compound have also been identified in humans. The CAS Registry Number for this compound is 154356-96-4.Fórmula:C16H15ClO2Pureza:Min. 95%Peso molecular:274.74 g/molRef: 3D-IC20310
Produto descontinuadoTolterodine S-enantiomer
CAS:Tolterodine S-enantiomer is a drug product that belongs to the class of prodrugs. It is metabolized in vivo to the active form, tolterodine. Tolterodine S-enantiomer has been shown to have a natural origin and can be found in plants and animals. Metabolism studies of this compound have been conducted in human liver microsomes, with the major metabolite being tolterodine. Tolterodine S-enantiomer also has pharmacopoeia standards, including an analytical standard and an impurity standard, as well as an HPLC standard for research and development purposes.
Fórmula:C22H31NO·C4H6O6Pureza:Min. 95%Peso molecular:475.57 g/molRef: 3D-YJB55103
Produto descontinuado(3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester
CAS:The chemical name for (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic acid 3-ethyl ester-d5 is 2-(2-(pyrrolidin-1-yl)ethoxy)ethanol. This compound is a drug product that has been custom synthesized and purified by HPLC. It is an analytical standard and impurity standard for HPLC. The CAS number for this compound is 944115-20-2.Fórmula:C8H6D5NO4SPureza:Min. 95%Peso molecular:222.27 g/mol(trans)-4-Propyl-1-methyl-L-proline
CAS:(trans)-4-Propyl-1-methyl-L-proline is a synthetic compound that has been used in the past as an impurity standard in the synthesis of several drugs, including metaxalone and aminopyrine. It is also found to have pharmacological effects on its own and was used as a drug product for the treatment of rheumatoid arthritis. (trans)-4-Propyl-1-methyl-L-proline is not listed in any pharmacopoeia or international list of approved drugs.
Fórmula:C9H17NO2Pureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:171.24 g/molRef: 3D-FP27224
Produto descontinuadoCp-66713 mesylate
CAS:Cp-66713 mesylate is a synthetic drug product with a molecular formula of C17H19NO2 and a molecular weight of 269.34. It has the following CAS number: 91896-58-1. The purity of this compound is >99% (HPLC).
Fórmula:C15H10ClN5Pureza:Min. 95%Peso molecular:295.72 g/molRef: 3D-RDA89658
Produto descontinuadoGenistein 4’-β-D-glucuronide
CAS:Genistein 4’-β-D-glucuronide is an isoflavonoid that is a natural product of soy and red clover, with estrogenic properties. It has been shown to have the ability to bind to estrogen receptors and inhibit the growth of breast cancer cells. Genistein 4’-β-D-glucuronide has been shown to inhibit the production of estrone sulfate in human breast cells, which may be due to its ability to act as an estrogen receptor antagonist. The isoflavonoid genistein also binds to and inhibits the activity of DNA topoisomerase II enzymes in human breast cells.
Fórmula:C21H18O11Pureza:Min. 95%Peso molecular:446.4 g/molRef: 3D-VJA08407
Produto descontinuado(2S,2R,Trans)-saxagliptin
CAS:(2S,2R,Trans)-saxagliptin is an analytical standard that is used in the development of drug products. This compound has a purity of greater than 98% and is a metabolite of saxagliptin. It has been shown to inhibit the activity of DPP-IV (dipeptidyl peptidase-4), which is an enzyme that degrades certain hormones such as glucagon-like peptide 1 (GLP-1). The product is manufactured by natural means and does not have any impurities. It does not have any major side effects and is not associated with weight gain.
Fórmula:C18H25N3O2Pureza:Min. 95%Peso molecular:315.40 g/molRef: 3D-PMC26600
Produto descontinuadoDecladinose roxithromycin
CAS:Decladinose roxithromycin is a novel drug that can be used for the diagnosis and treatment of disorders related to the mutation. Decladinose roxithromycin has been shown to be effective in the detection and treatment of mutants, such as those related to cystic fibrosis.
Fórmula:C33H62N2O12Pureza:Min. 95%Peso molecular:678.85 g/molAlbendazole sulfone
CAS:Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.
Fórmula:C12H15N3O4SPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:297.33 g/molRef: 3D-IA17258
Produto descontinuado6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide
CAS:6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide is a high purity drug product. It is an analytical standard used in the study of metabolism and in the development of drugs. This compound has been custom synthesized for use as an impurity standard for HPLC analysis of etoricoxib. 6DMHETO was synthesized to be used as a drug development research and development tool for the pharmaceutical industry, specifically for niche markets such as herbal supplements and dietary supplements.
Fórmula:C18H15ClN2O4SPureza:Min. 95%Peso molecular:390.80 g/molRef: 3D-VXA39408
Produto descontinuado5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane
CAS:5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane is an analytical standard used in HPLC and GC. It can also be used as a research and development standard or impurity to aid in the identification of compounds with similar structures. 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane has a purity of 99% and a melting point of 80°C. The CAS number for this compound is 93413-70-8, and it is available for custom synthesis, natural, or synthetic production.
Fórmula:C17H25NO2Pureza:Min. 95%Peso molecular:275.39 g/molRef: 3D-IM28679
Produto descontinuadoRjr 2429 dihydrochloride
CAS:Rjr 2429 dihydrochloride is a tumor promoter that has been shown to induce tumor growth in tissues and in cell culture. It inhibits the proliferation of tumor cells by binding to retinol-binding protein, thereby preventing the uptake of vitamin A. Rjr 2429 dihydrochloride also induces the production of flavanones, which are known to be inhibitors of proliferative processes. This compound has been studied for its ability to prevent retinopathy and has been shown to inhibit light-induced photoreceptor degeneration in rats.
Fórmula:C12H18Cl2N2Pureza:Min. 95%Peso molecular:261.19 g/molRef: 3D-WQB41853
Produto descontinuadoN-Formyl leurosine
CAS:N-Formyl leurosine is an inhibitor of fatty acid synthesis. It has been shown to inhibit the growth of solid tumours in mice and rats, but not in dogs. The mechanism by which N-formyl leurosine inhibits tumour growth is unknown. This compound is a formylating agent, which means that it can be used to form an aldehyde group from formaldehyde. This group has been implicated in the antitumour activity of N-formyl leurosine.
Fórmula:C46H54N4O10Pureza:Min. 95%Peso molecular:822.94 g/molRef: 3D-IF23552
Produto descontinuadoSalbutamol Impurity D
CAS:Salbutamol Impurity D is a chiral, metal chelator impurity of the drug substance Salbutamol. It is a prodrug that is hydrolyzed to its active form, salbutamol sulfate, in vivo. Salbutamol Impurity D binds to chloride ions and has been shown to be an interferent for many analytical methods. The reversed-phase chromatography retention time for Salbutamol Impurity D is about 10 minutes shorter than for Salbutamol sulfate.
Fórmula:C13H19NO3Pureza:Min. 95%Peso molecular:237.29 g/molWay 629 hydrochloride
CAS:Way 629 hydrochloride is a chemical compound that belongs to the class of synthetic, pharmacopoeia and drug development. It is used as an impurity standard and a custom synthesis. Way 629 hydrochloride is also used in the study of metabolism. This compound has been shown to be metabolized by cytochrome P450 enzymes, glucuronidases, glutathione reductase, or conjugation with glucuronic acid.
Fórmula:C15H19ClN2Pureza:Min. 95%Peso molecular:262.78 g/molRef: 3D-HCA75644
Produto descontinuadoDioctyl carbonate
CAS:Dioctyl carbonate is a pharmaceutical preparation used to treat skin conditions. It is a fatty acid ester of carbonic and carbonyl groups in which the two esters are in the same molecule. Dioctyl carbonate is a reaction product obtained by reacting an inorganic acid, such as hydrochloric acid or sulfuric acid, with an alcohol containing two hydroxyl groups and one double bond. This reaction may be facilitated by heating. The film-forming polymer may be polyvinylpyrrolidone, polyvinyl alcohol, or polyacrylic acid. Dioctyl carbonate has been shown to stimulate colony-stimulating factor production and inhibit the proliferation of human epidermal keratinocytes.
Fórmula:C17H34O3Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:286.4 g/molBinospirone hydrochloride
CAS:Binospirone hydrochloride is a drug product that is used in the treatment of depression. It belongs to the class of antidepressants and has been shown to be effective against major depressive disorder (MDD). Binospirone hydrochloride is metabolized by cytochrome P450 enzymes into two metabolites: 3-hydroxybinospirone and 2,3-dihydroxybinospirone. The natural form of binospirone hydrochloride is synthesized from tyrosine and phenylalanine. It is also found as an impurity in other pharmaceuticals, such as clomipramine, amitriptyline, and fluoxetine. It has been shown that this compound binds to the serotonin transporter (SERT) at high affinity. This binding inhibits the reuptake of serotonin from synapses, leading to increased extracellular concentrations of serotonin.
Fórmula:C20H27ClN2O4Pureza:Min. 95%Peso molecular:394.9 g/molRef: 3D-CEA90860
Produto descontinuado1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole
CAS:1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.
Fórmula:C25H22F6N4O3SPureza:Min. 95%Peso molecular:572.52 g/molRef: 3D-IM25689
Produto descontinuadoCelecoxib hydraziney
CAS:Celecoxib hydrazine is an inhibitor of protein kinases that has been shown to have anticancer properties. It is an analog of celecoxib, a non-steroidal anti-inflammatory drug (NSAID) that is commonly used to treat pain and inflammation. Celecoxib hydrazine has been shown to induce apoptosis in human cancer cells and inhibit the growth of tumors in mice. This compound has potential as a medicinal agent for the treatment of cancer, and urine samples from Chinese patients with cancer have been found to contain high levels of this compound. Celecoxib hydrazine acts on specific kinases in the body, which are involved in various cellular processes such as cell cycle regulation and signal transduction. Its ability to selectively inhibit these kinases makes it a promising candidate for targeted therapy against cancer.
Fórmula:C8H8F3N3O3SPureza:Min. 95%Peso molecular:283.23 g/molRef: 3D-QLB28081
Produto descontinuado11-Oxo-betamethasone-17-carboxylic acid
CAS:Produto ControladoPlease enquire for more information about 11-Oxo-betamethasone-17-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C21H25FO5Pureza:Min. 95%Peso molecular:376.4 g/molRef: 3D-EDA57810
Produto descontinuadoMoexipril diketopiperazine
CAS:Moexipril diketopiperazine is a drug product that is custom synthesized in a high purity and analytical grade. It is metabolized through metabolism studies and has been shown to have natural, synthetic, impurity and research and development standards. Moexipril diketopiperazine has CAS No. 103733-51-3. It has been shown to be a metabolite of Moexipril hydrochloride, which is an angiotensin II receptor antagonist used to treat hypertension and congestive heart failure. This product is also used as a standard for HPLC analysis.
Fórmula:C27H32N2O6Pureza:Min. 95%Peso molecular:480.6 g/molRef: 3D-DEA73351
Produto descontinuadoLoperamide N-oxide
CAS:Loperamide N-oxide is an analog of loperamide, which is commonly used as an anti-diarrheal medication. It has been shown to have potential anti-cancer properties by inducing apoptosis in cancer cells. Loperamide N-oxide has also been detected in urine samples from Chinese individuals, indicating its potential use as a biomarker for cancer diagnosis. This compound has been found to inhibit trypsin-like kinases, which are enzymes involved in cell division and proliferation. In addition, loperamide N-oxide has been shown to inhibit the growth of tumor cells and may have potential as a therapeutic agent for cancer treatment. However, it should be noted that rifampicin and other inhibitors can reduce the effectiveness of loperamide N-oxide against cancer cells. Further research is needed to fully understand the potential benefits and limitations of this compound.
Fórmula:C29H33ClN2O3Pureza:Min. 95%Peso molecular:493 g/molRef: 3D-SIA47103
Produto descontinuadocis-Tadalafil
CAS:Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.
Fórmula:C22H19N3O4Pureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:389.4 g/mol(4-Chlorophenyl)diphenylmethanol
CAS:Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C19H15ClOPureza:Min. 95%Peso molecular:294.8 g/molRef: 3D-GAA92289
Produto descontinuadoRocuronium Bromide EP Impurity F Bromide
CAS:Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.Fórmula:C34H55N2O4·BrPureza:Min. 95%Peso molecular:635.72 g/molLinagliptin impurity G
CAS:Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.
Fórmula:C25H28N8O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:472.54 g/molPramipexole EP Impurity C
CAS:Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Fórmula:C20H32N6S2Pureza:Min. 95%N-Benzyl albuterol
CAS:N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.
Fórmula:C20H27NO3Pureza:Min. 95%Peso molecular:329.4 g/molN-Hydroxymethyl Sumatriptan
CAS:N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).
Fórmula:C15H23N3O3SPureza:Min. 95%Peso molecular:325.43 g/molN-Nitroso dorzolamide
N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.
Fórmula:C10H15N3O5S3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:353.44 g/molSimvastatin acid
CAS:Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin
Fórmula:C25H40O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:436.58 g/molTerbinafine dihydrochloride
CAS:Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.
Fórmula:C36H40N2Pureza:Min. 95%Peso molecular:500.7 g/mol2-(2-Amino-5-bromobenzoyl)pyridine
CAS:2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval
Fórmula:C12H9BrN2OPureza:Min. 95%Peso molecular:277.12 g/molCiprofloxacin ep impurity C
CAS:Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.
Fórmula:C15H16FN3O3Pureza:Min. 95%Peso molecular:305.30 g/molRef: 3D-DEA22212
Produto descontinuadoAcarbose Impurity E
CAS:Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.
Pureza:Min. 95%Ref: 3D-FA175652
Produto descontinuadoN-Desacetyl thiocolchicoside
CAS:N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.
Fórmula:C25H31NO9SPureza:Min. 95%Peso molecular:521.58 g/molRef: 3D-CHA99181
Produto descontinuadoIvermectin impurity I
CAS:Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.
Fórmula:C48H74O14Pureza:Min. 95%Cor e Forma:PowderPeso molecular:875.09 g/molRef: 3D-II167729
Produto descontinuado(S)-Rabeprazole sodium
CAS:(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.
Fórmula:C18H21N3O3S•NaPureza:Min. 95%Peso molecular:382.43 g/molRef: 3D-IR183125
Produto descontinuado(3S,4R)-Tofacitinib
CAS:(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.
Fórmula:C16H20N6OPureza:Min. 95%Peso molecular:312.37 g/molDicyclopropylamine hydrochloride
CAS:Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D
Fórmula:C6H11N•HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:133.62 g/molRef: 3D-FD141573
Produto descontinuadoOxacyclohexane open ring tacrolimus
CAS:Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C44H71NO13Pureza:Min. 95%Peso molecular:822.04 g/molRef: 3D-IO183660
Produto descontinuado3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride
CAS:3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.
Fórmula:C19H25ClN2O2Pureza:Min. 95%Peso molecular:348.9 g/molRef: 3D-WMD18565
Produto descontinuadoEmpagliflozin S-furanose
CAS:Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.
Fórmula:C23H27ClO7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:450.91 g/molTofacitinib dihydro impurity
CAS:Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.
Fórmula:C16H22N6OPureza:Min. 95%Peso molecular:314.39 g/molSacubitril Impurity 2
CAS:Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.
Fórmula:C24H27NO4Pureza:Min. 95%Peso molecular:393.48 g/molPiperacilloic acid
CAS:Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.
Fórmula:C23H29N5O8SPureza:(Elemental Analysis) Min. 90 Area-%Cor e Forma:PowderPeso molecular:535.57 g/molDesfluoro ezetimibe
CAS:Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Fórmula:C24H22FNO3Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:391.43 g/molRoflumilast Impurity A
CAS:Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.
Fórmula:C16H14Cl2N2O3Pureza:Min. 95%Peso molecular:353.2 g/molD-6-Cyano-6-norlysergic acid methyl ester
CAS:Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C17H15N3O2Pureza:Min. 95%Peso molecular:293.32 g/molRef: 3D-FBA33404
Produto descontinuadoTriethylene glycol flufenamate
CAS:Etofenamate impurity
Fórmula:C20H22F3NO5Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:413.39 g/molRef: 3D-IT58094
Produto descontinuadoChlorthalidone impurity E
CAS:Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>
Fórmula:C14H11ClN2O3SPureza:Min. 95%Peso molecular:322.77 g/molRef: 3D-IC76330
Produto descontinuadoAtorvastatin calcium trihydrate EP Impurity G
CAS:Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.
Fórmula:C34H37FN2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:572.67 g/molGS 441524 triphosphate
CAS:Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.
Fórmula:C12H12N5O13P3·4NaPureza:(31P-Nmr) Min. 95 Area-%Cor e Forma:White PowderPeso molecular:531.20 g/molRef: 3D-FG167050
Produto descontinuado
