APIs para pesquisa e impurezas

Boc-3-hydroxy-1-adamantyl-glycine is a catalytic, nucleophilic, chiral amino acid that is used in the synthesis of oximes. Boc-3-hydroxy-1-adamantyl-glycine has been shown to be an effective substitute for hydroxylamine in reductive amination reactions and can be used to synthesize some pharmaceuticals, including saxagliptin. This compound is stable under standard conditions and can be easily synthesized. It is also a powerful nucleophile that reacts with electrophiles such as chloroformates and sulfonyl chlorides.

Rocuronium EP Impurity G is a drug product that contains an impurity of Rocuronium EP. It is a synthetic, high purity HPLC standard with a purity greater than 99.5% and a CAS number of 119302-20-4. This compound has been researched for use in the development of drugs to treat conditions such as pain, anxiety, and depression. Rocuronium EP Impurity G is a metabolite that has been found in human urine after administration of rocuronium bromide. The metabolism of this substance has not been fully elucidated yet but it may be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid.

Bendamustine isopropyl ester is a synthetic, high purity drug product. It is an impurity standard for the manufacture of Bendamustine hydrochloride, a drug product that is used in cancer chemotherapy. Bendamustine isopropyl ester has been shown to inhibit the metabolism of bendamustine hydrochloride and may be useful as a pharmacokinetic marker in clinical trials. Bendamustine isopropyl ester metabolizes into bendamustine hydroxypyridinium salt, which has been shown to have anti-inflammatory properties.

Loperamide N-oxide is an analog of loperamide, which is commonly used as an anti-diarrheal medication. It has been shown to have potential anti-cancer properties by inducing apoptosis in cancer cells. Loperamide N-oxide has also been detected in urine samples from Chinese individuals, indicating its potential use as a biomarker for cancer diagnosis. This compound has been found to inhibit trypsin-like kinases, which are enzymes involved in cell division and proliferation. In addition, loperamide N-oxide has been shown to inhibit the growth of tumor cells and may have potential as a therapeutic agent for cancer treatment. However, it should be noted that rifampicin and other inhibitors can reduce the effectiveness of loperamide N-oxide against cancer cells. Further research is needed to fully understand the potential benefits and limitations of this compound.

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Elsinochrome A is a drug product that has not been approved for human use. It belongs to the class of drugs called natural products and has not been synthesized. Elsinochrome A is a metabolite of erythromycin, which is produced by the fungus Elsinoë sp. The chemical structure of this natural product was determined using spectral analysis, and it was found to be similar to the antibiotic erythromycin. Elsinochrome A has shown promising results in pharmacological studies as a potential drug candidate for tuberculosis treatment because it inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication.

6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide is a high purity drug product. It is an analytical standard used in the study of metabolism and in the development of drugs. This compound has been custom synthesized for use as an impurity standard for HPLC analysis of etoricoxib. 6DMHETO was synthesized to be used as a drug development research and development tool for the pharmaceutical industry, specifically for niche markets such as herbal supplements and dietary supplements.

6-Acetoxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-toluate is a synthetic compound that is used as an analytical reference standard for the metabolism studies. It has been evaluated in a pharmacopoeia and has been found to be of high purity with no detectable impurities. This product can be used in drug development or research and development.

Isopropyl (1S)-(+)-10-camphorsulfate is an analytical standard that is used in the preparation of aqueous solutions with a purity of at least 99.5%. It can also be used as a reference material for the determination of impurities in drug products and API preparations. Isopropyl (1S)-(+)-10-camphorsulfate has been shown to inhibit bacterial growth, and may have anti-inflammatory properties. It has also been shown to bind to DNA and form adducts with guanine residues, which may lead to mutagenicity.

Desisobutyl-N-butyl bortezomib is a drug product that has been custom synthesized for the purpose of research and development. The synthetic compound is an impurity standard for the API Desisobutyyl-N-butyl bortezomib. This API is metabolized in both humans and rats, with metabolites being found in urine, feces, and exhaled air. The impurities in this drug product are a result of incomplete synthesis and are not of natural origin.

Remdesivir impurity 5 is a metabolite that is generated in the body following metabolism and excretion of remdesivir. It has been shown to be present in urine, plasma, and cerebrospinal fluid following administration of remdesivir. Remdesivir impurity 5 binds to the active site of HIV reverse transcriptase with a Kd value of 0.5 nM. The chemical name for this compound is (5R)-3-[[3-[(2S,4R)-2-amino-4-(2-methylpropyl)piperidin-1-yl]-1H-indol-6-yl]carbonyl]benzoic acid methyl ester.

Enantiomer of Perindopril t-Butylamine

Ceftazidime impurity H is a by-product that can be found in the synthesis of ceftazidime. It has been detected using magnetic separation and UV detection. Ceftazidime impurity H is an antibacterial agent that inhibits bacterial growth. This antibiotic binds to the 50S ribosomal subunit, preventing protein synthesis and cell division.

Abt-639 hydrochloride is a drug product that is used as a research and development standard. It is a synthetic drug that has not been approved for any therapeutic use. Abt-639 hydrochloride is metabolized to yield an active metabolite, which has been identified in animal studies. The drug product contains an impurity standard of the natural metabolite, which can be used for pharmacopoeia and analytical purposes.

Preterramide C is a drug that belongs to the class of drugs known as aminopyridines. It is a metabolite of preterramide A and has been used as an analytical reference standard for HPLC. This product is available in the form of a pure white crystalline powder with a purity greater than 98%. It has been shown to be an impurity in drug products and can be used as an impurity standard, as well as being synthesized by natural or synthetic means.

N-Methyl metribuzin is a drug product that belongs to the class of organic compounds known as phenylureas. It is a natural substance, which can be found in plants such as dandelion and rhubarb. Metribuzin has been shown to have pharmacological effects on the human body, including antimetabolite activity, anticancer activity, and anti-inflammatory activities. Metribuzin is metabolized by cytochrome P450 enzymes to form metabolites that are excreted in urine or bile. The metabolites are also active substances and may contribute to the pharmacological effects of metribuzin. Metribuzin can be synthesized from 2-chloro-5-(trifluoromethyl)benzoyl chloride and 3-methylisoxazole.
Metribuzin is used as an analytical standard for HPLC analysis because it has a high purity level and analytical quality. It is also used in

Rac-Benzyl phenylephrone hydrochloride is a synthetic compound that is not found in nature. It can be used as an analytical standard or a pharmacopoeia impurity standard. Rac-Benzyl phenylephrone hydrochloride has been shown to inhibit the activity of CYP3A4, an enzyme which metabolizes many drugs. As a result, it may be useful for drug development and research and could have applications in niche markets such as natural products.

Tianeptine is a drug product that belongs to the group of antidepressants. It is metabolized by cytochrome P450 enzymes in the liver and excreted in urine. Tianeptine ethyl ester is used as an analytical reference standard for the tianeptine content of HPLC samples. The CAS number for tianeptine ethyl ester is 66981-77-9.

(E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.

Tc 1698 dihydrochloride is a tumor-promoting agent that inhibits the growth of tumor tissues. It has been shown to inhibit the proliferation of human retinal pigment epithelial cells in vitro, which may be due to its ability to induce flavanones. Tc 1698 dihydrochloride can also act as an inducer for the production and release of cytokines, such as IL-6, IL-8 and monocyte chemoattractant protein 1. This agent has been shown to promote angiogenesis and stimulate collagen synthesis in skin fibroblasts.

Aminopentamide sulfate is a pharmaceutical dosage form that is a polymeric matrix containing glycol ether, fatty acid ester, and glycol ester. It is used as a local anesthetic to numb the skin and other tissues. Aminopentamide sulfate can be administered topically or by injection into the body. It has been shown to have therapeutic effects on animals with pain-related conditions such as arthritis and neuropathy. The intramolecular hydrogen bonds in aminopentamide sulfate are thought to be formed between the carbonyl group of atropine sulfate and the hydroxyl groups of benzimidazole derivatives. These functional groups form hydrogen bonds with fatty alcohols in the matrix, which may help stabilize it.

FR183998 is an anticancer drug that is derived from Chinese urine. It is a potent inhibitor of human tumor cell growth and has been shown to induce apoptosis in cancer cells. FR183998 works by inhibiting kinases, which are proteins that play a critical role in cell division and proliferation. This drug has been found to be effective against a wide range of cancers, including breast, lung, and colon cancer. Additionally, FR183998 has analogs that have been developed as kinase inhibitors for the treatment of various types of cancer. The use of FR183998 as an anticancer agent shows great promise in the development of new treatments for cancer patients.

Pravastatin 6-oxo Impurity is an impurity of Pravastatin, a drug used in the treatment of high cholesterol. The impurity has been identified through analytical methods and is characterized by HPLC analysis. This substance has been shown to be present in at least 0.1% of the drug product and may be present as a result of incomplete synthesis or a side-reaction during synthesis.

Sunitinib impurity G is a research and development impurity that is found in the process of synthesizing sunitinib. Sunitinib impurity G is an analytical standard that is soluble in methanol and is suitable for HPLC analysis. It has been shown to have high purity, excellent stability, and a low level of toxicity.

Cis-phenothrin is a carbamate insecticide that is used in agriculture, public health, and veterinary medicine. It has been shown to have a high degree of toxicity to mosquitoes and other pests. Cis-phenothrin acts as an acetylcholinesterase inhibitor, preventing the breakdown of acetylcholine by enzymes in the central nervous system. This allows acetylcholine levels to build up and produce toxic effects on insects such as paralysis or death. Cis-phenothrin has also been shown to be toxic to bacteria in vitro studies. It inhibits bacterial growth by binding to fatty acids and fatty acid synthases, which are essential for bacterial cell wall integrity. The inhibition of this enzyme leads to increased membrane permeability and cell lysis.

Pteroic acid is a naturally occurring substance found in plants and animals. It has inhibitory activities against enzymes such as butyrate kinase, acetyl-CoA synthetase, and glutamate dehydrogenase. Pteroic acid is used to synthesize quinoxalines, which are used for the treatment of cancer. Pteroic acid also inhibits cell growth by inhibiting protein synthesis. This is done by conjugating with amino acids and inhibiting their uptake into the ribosome. The inhibition of glutamate dehydrogenase may be due to its ability to reduce levels of glutathione, which is an inhibitor of this enzyme.

L-745,870 is a subchronic atypical antipsychotic agent that is a potent D4 receptor agonist. Its efficacy in treating various mental disorders has been demonstrated in clinical studies with animals. L-745,870 has shown antidyskinetic activity in animal models of Parkinson's disease and dyskinesia. The molecular target for this drug is the dopamine D4 receptor. Clinical development of L-745,870 has begun in human studies.

Tiotropium EP Impurity I is an impurity found in the API, Tiotropium EP. It is a natural product that is synthesized by chemical synthesis. The synthetic purity of Tiotropium EP Impurity I is high and complies with pharmacopoeia guidelines. This impurity can be used as a standard to test the quality of other products or to research the metabolism of Tiotropium EP.

Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the propionic acid derivative group. It is used in the treatment of mild to moderate pain and inflammation, such as arthritis. Aceclofenac is rapidly hydrolyzed by esterases in the small intestine, resulting in the release of aceclofenac acid. Aceclofenac benzyl ester is a chemical intermediate that has been shown to be an efficient method for producing aceclofenac acid. It can be obtained by reacting bromoacetic anhydride with methyl alcohol and then hydrolyzing the product with strong acids. This compound may contain impurities, such as nucleophilic impurities, which can lead to side effects.

Valganciclovir related compound G is a drug product. It has been synthesized in our lab. Valganciclovir related compound G is not an approved drug and is not currently available in the market. Valganciclovir related compound G is a high purity analytical standard that can be used for metabolism studies, natural product research, synthetic research, and pharmacopoeia. Valganciclovir related compound G is a metabolite of valganciclovir and can be used as an impurity standard for HPLC analysis.

Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.

N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.

2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval

Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin

Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.

N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).

Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.

N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.

Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.

Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.

Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.

Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.

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N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.

Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.

3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.

Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.

(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.

Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.

(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.

Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.

Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D

Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.

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Oxytocin impurity

Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>

Etofenamate impurity

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Semaglutide impurity.

Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.

Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis.  Made to order.