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APIs para pesquisa e impurezas

APIs para pesquisa e impurezas

Os Ingredientes Farmacêuticos Ativos (APIs) são as substâncias nos medicamentos responsáveis por seus efeitos terapêuticos. Nesta seção, você encontrará uma ampla variedade de APIs destinados a uso em pesquisa. Esses compostos são essenciais para o desenvolvimento, teste e validação de novas formulações farmacêuticas. Na CymitQuimica, oferecemos APIs de alta qualidade para apoiar a pesquisa em descoberta e desenvolvimento de medicamentos.

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  • N-Desmethyl trimeprazine

    CAS:

    N-Desmethyl trimeprazine is a synthetic compound, which is an impurity of the drug product. It is not active and does not possess any biological activity. It is a metabolite of the parent drug, Trimeprazine. N-Desmethyl trimeprazine has been studied for its pharmacological properties and metabolism in the body, but no conclusive results have been found. The chemical structure and purity of N-Desmethyl trimeprazine are not listed in the USP or BP. This compound can be custom synthesized on request.

    Fórmula:C17H20N2S
    Pureza:Min. 95%
    Peso molecular:284.40 g/mol

    Ref: 3D-XAA73204

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  • Miproxifene

    Produto Controlado
    CAS:

    Miproxifene is a potent anticancer drug that has been shown to induce apoptosis and inhibit cell cycle progression in human cancer cells. This drug has been extensively studied in Chinese hamster ovary (CHO) cells and has demonstrated significant activity against various types of cancer, including leukemia. Miproxifene acts as a protein inhibitor and has been found to be effective against several tumor cell lines. It is a promising medicinal compound for the treatment of cancer, with potential applications in both chemotherapy and radiation therapy. Miproxifene is excreted primarily through urine and is well-tolerated by patients. Its use as an anticancer agent holds great promise for the future of cancer treatment.

    Fórmula:C29H35NO2
    Pureza:Min. 95%
    Peso molecular:429.6 g/mol

    Ref: 3D-EFA61287

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  • (2R)-3-Hydroxyisovaleroyl carnitine

    CAS:

    (2R)-3-Hydroxyisovaleroyl carnitine is a synthetic drug product that is used as an analytical reagent for the detection of (R)-3-hydroxyisovaleryl carnitine in metabolism studies. It has a CAS number of 99159-87-2 and a molecular weight of 212.29 g/mol. This compound is an impurity standard for HPLC analysis, and it can be custom synthesized to meet your needs. Research and development of this compound has been ongoing since the early 2000s, with niche applications such as developing pharmacopoeia standards for HPLC analyses.

    Fórmula:C12H23NO5
    Pureza:Min. 95%
    Peso molecular:261.31 g/mol

    Ref: 3D-ZDA15987

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  • Cycrimine hydrochloride

    CAS:

    Cycrimine hydrochloride is a molecule that is used as an anticholinergic drug. It has been shown to be effective in humans, with a half life of 3 hours and a duration of action of 8 hours. Cycrimin hydrochloride is also used as a diagnostic agent for irritant contact dermatitis and may be useful in the diagnosis of other allergic reactions. The molecule is also used as a diagnostic aid for cardiac arrhythmias.

    Fórmula:C19H30ClNO
    Pureza:Min. 95%
    Peso molecular:323.9 g/mol

    Ref: 3D-AAA12602

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  • Methiotepa

    CAS:

    Methiotepa is a potent anticancer drug that has been used for the treatment of various types of tumors. It is a Chinese hamster ovary (CHO) cell-derived analog of chitin, which inhibits the activity of protein kinase C. Methiotepa induces apoptosis in cancer cells by inhibiting DNA synthesis and repair, leading to cell death. This drug has also been shown to be a potent inhibitor of heparin-induced platelet aggregation in human blood. Methiotepa has been found to be effective against a wide range of cancers, including breast, lung, ovarian, and bladder cancer, among others. Its use as an anticancer agent may be due to its ability to inhibit the activity of various kinases and other enzymes involved in cancer cell proliferation and survival.

    Fórmula:C9H18N3PS
    Pureza:Min. 95%
    Peso molecular:231.3 g/mol

    Ref: 3D-AAA07696

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  • Piquindone

    CAS:

    Piquindone is a medicinal compound that has shown promising anticancer properties in human tumor cells. It acts as an inhibitor of protein kinases, which are enzymes that regulate cell growth and division. Piquindone is an analog of a natural product found in Chinese urine and has been studied for its ability to induce apoptosis, or programmed cell death, in cancer cells. This compound has shown potent activity against various types of cancer cells and may have potential as a therapeutic agent for the treatment of cancer. Its mechanism of action involves the inhibition of specific kinases involved in cancer cell proliferation and survival. Piquindone is being investigated further for its potential as a cancer cell inhibitor.

    Fórmula:C15H22N2O
    Pureza:Min. 95%
    Peso molecular:246.35 g/mol

    Ref: 3D-DDA54197

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  • Xanthoxin

    CAS:

    Xanthoxin is a medicinal compound with potent anticancer properties. It has been shown to induce apoptosis, or programmed cell death, in cancer cells. Xanthoxin has been tested in various cancer cell lines, including Chinese and human cells, and has demonstrated strong inhibitory effects on the tumor cycle. This compound works by inhibiting kinases and other proteins involved in cancer cell growth and proliferation. Xanthoxin is also known to be an inhibitor of certain urinary proteins that are associated with cancer progression. Overall, Xanthoxin shows great potential as a natural product for the development of novel anticancer therapies.

    Fórmula:C15H22O3
    Pureza:Min. 95%
    Peso molecular:250.33 g/mol

    Ref: 3D-IAA06607

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  • 2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole

    CAS:

    2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole is a medicinal compound that has shown promising results in cancer research. It works as an inhibitor of cyclin-dependent kinases, which are essential for cancer cell proliferation. This compound induces apoptosis in cancer cells by inhibiting the activity of certain proteins involved in tumor growth. Studies have shown that 2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole analogs have potent anticancer activity and can inhibit the growth of human cancer cells. This compound has also been found to be present in urine samples from Chinese patients with cancer. Further research on this compound may lead to the development of new and effective treatments for various types of cancers.

    Fórmula:C14H14N2
    Pureza:Min. 95%
    Peso molecular:210.27 g/mol

    Ref: 3D-XAA12667

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  • Nitrosoantipyrine

    CAS:

    Nitrosoantipyrine is a diagnostic agent that can be used to detect the presence of antitumour activity by examining the effects of nitrosation on cervical cancer cells. In this assay, nitrosation is induced by incubating cells in the presence of hydrochloric acid and sodium citrate. The reaction products are then examined for their ability to inhibit the growth of typhimurium. Nitrosoantipyrine can be used as an antitumour agent or dietary supplement to reduce risk factors associated with carcinogens. Coumarin derivatives are often used as a precursor for nitrosoantipyrine synthesis because they react readily with nitrous acid at room temperature and form a stable product without any side reactions.

    Fórmula:C11H11N3O2
    Pureza:Min. 95%
    Peso molecular:217.22 g/mol

    Ref: 3D-AAA88511

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  • 7-Chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester

    CAS:

    7-Chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester is a synthetic compound that has not been evaluated in humans. Studies have shown that the drug can be hydrolyzed to 7-chloro-6-fluoroquinoline 1,1′-(ethylenedioxy)bis(ethane), which is an impurity of norfloxacin. The ethyl esters of 7-chloroquinoline are also known to condense with formaldehyde and hydrolyze to 7-chloroquinolinic acid. This product may contain solvents such as acetone, chloroform, and alcohols that are used during the synthesis process. Decarboxylation of the drug occurs when it is heated at high temperatures in the presence of a catalyst, such as pyridine or sodium methoxide. It decarboxyl

    Fórmula:C12H9ClFNO3
    Pureza:Min. 95%
    Peso molecular:269.65 g/mol

    Ref: 3D-ADA07315

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  • N-Desethyl-E-clomiphene hydrochloride

    CAS:

    N-Desethyl-E-clomiphene hydrochloride is a synthetic drug product that has been custom synthesized to meet the needs of our customer. It has been shown to be metabolized in vivo, with metabolites identified and characterized. This drug product is a synthetic, natural, and impurity standard. Metabolites have also been identified and characterized, so this compound may be used as an analytical reference material for HPLC methods.

    Fórmula:C24H24ClNO•HCl
    Pureza:Min. 95%
    Peso molecular:414.37 g/mol

    Ref: 3D-WAA62570

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  • Imidafenacin metabolite M4

    CAS:

    Imidafenacin metabolite M4 is a synthetic impurity of imidafenacin. It is an API impurity as it is produced during the synthesis of this drug. Imidafenacin metabolite M4 has been shown to be present in high purity and is used as a pharmacopoeia standard. The compound has been studied for its metabolism, which includes studies on its ability to inhibit cytochrome P450 enzymes and other drug-metabolizing enzymes, as well as its potential to cause drug interactions.

    Fórmula:C18H19N3O3
    Pureza:Min. 95%
    Peso molecular:325.40 g/mol

    Ref: 3D-DVA59817

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  • Olaparib impurity 14

    CAS:

    Olaparib impurity 14 is a metabolite of olaparib. Olaparib is a drug used to treat cancer by inhibiting the activity of PARP1, an enzyme that repairs DNA damage. This impurity is a compound that can be synthesized in high purity and quality with a custom synthesis service. It has been shown to have niche applications in pharmacopoeia, drug development, and analytical studies.

    Fórmula:C36H28F2N6O4
    Pureza:Min. 95%
    Peso molecular:646.6 g/mol

    Ref: 3D-AQD24262

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  • Pirtenidine

    CAS:

    Pirtenidine is a potent and selective kinase inhibitor that has been shown to inhibit the activity of cyclin-dependent kinases. It has demonstrated promising results in preclinical studies as an anticancer agent, inducing apoptosis in cancer cells. Pirtenidine is an analog of protein kinase inhibitors, which have been used to treat various types of tumors. It has been found to be effective against human cancer cell lines and has shown significant tumor growth inhibition in animal models. Pirtenidine has also been reported to be a potent urine inhibitor of Chinese hamster ovary cells, making it a promising candidate for the treatment of urinary tract cancers.

    Fórmula:C21H38N2
    Pureza:Min. 95%
    Peso molecular:318.5 g/mol

    Ref: 3D-DEA92327

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  • Fonofos

    CAS:

    Fonofos is a potent inhibitor that has been shown to induce apoptosis in Chinese hamster ovary cells. It is also known to inhibit chitin kinase, a protein that plays an important role in the biosynthesis of chitin, which is essential for the formation of cell walls in fungi and insects. Fonofos has medicinal properties and has been studied as a potential anticancer agent due to its ability to inhibit tumor growth. In vitro studies have shown that Fonofos can inhibit the growth of human cancer cells by inhibiting heparin-binding proteins. Additionally, it has been found to have inhibitory effects on several other enzymes involved in cancer development and progression. Although not approved for use in humans, Fonofos may hold promise as a therapeutic agent for the treatment of certain cancers.

    Fórmula:C10H15OPS2
    Pureza:Min. 95%
    Peso molecular:246.3 g/mol

    Ref: 3D-AAA94422

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  • Garamine acetate salt

    CAS:

    Gentamicin Impurity

    Fórmula:C13H27N3O6•(C2H4O2)x
    Pureza:Min. 95%
    Cor e Forma:Off-White Powder
    Peso molecular:321.37 g/mol

    Ref: 3D-OG46090

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  • Sitagliptin monohydrochloride monohydrate

    CAS:

    Sitagliptin monohydrochloride monohydrate is an inhibitor of dipeptidyl peptidase-4 (DPP-4), which is responsible for the degradation of incretin hormones. It is used in the treatment of type 2 diabetes mellitus, as it increases insulin secretion and reduces blood glucose levels. Recent studies have shown that Sitagliptin has anticancer properties, as it induces apoptosis in cancer cells. It also inhibits protein kinases, which are involved in tumor growth and metastasis. Capsaicin, a compound found in chili peppers, has been shown to enhance the anticancer activity of Sitagliptin in Chinese hamster ovary cells. The drug is excreted primarily through urine and has a low potential for drug interactions with other kinase inhibitors. Overall, Sitagliptin monohydrochloride monohydrate shows great promise as both a diabetes medication and an anticancer agent.

    Fórmula:C16H18ClF6N5O2
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:461.79 g/mol

    Ref: 3D-MJB15692

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  • (-)-Sabinene

    CAS:

    (-)-Sabinene is a natural compound found in urine and various medicinal plants, including Chinese herbs. It has been identified as an analog of another natural compound that exhibits potent anticancer activity. (-)-Sabinene has been shown to inhibit the activity of certain proteins involved in cell cycle regulation and apoptosis, which are important processes for the growth and survival of cancer cells. In addition, (-)-Sabinene has been found to have inhibitory effects on tumor kinase activity, making it a promising candidate for the development of new anticancer drugs. Studies have shown that (-)-Sabinene can effectively inhibit the growth of various types of cancer cells, making it a potential therapeutic agent for the treatment of cancer.

    Fórmula:C10H16
    Pureza:Min. 95%
    Cor e Forma:Clear Liquid
    Peso molecular:136.23 g/mol

    Ref: 3D-KAA40816

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