APIs para pesquisa e impurezas

<p>Amlodipine besilate impurity D oxalate salt is a pharmaceutical ingredient that is an impurity in Amlodipine besilate and is used as a diluent. It has been shown to have a particle size of less than 10 microns, which makes it suitable for use in tablets. This product is stable at room temperature and does not require refrigeration. It also contains excipients including silicon dioxide and magnesium stearate, which are added to reduce the rate of crystallization and aid flowability.</p>

<p>2,3,4',5-Tetrachlorobiphenyl is a chemical compound that has been shown to have anticancer properties. Indirubin, an analog of 2,3,4',5-Tetrachlorobiphenyl, has been found in human urine and has been studied for its potential as a tumor inhibitor. This compound inhibits kinases and proteins that are involved in cancer cell growth and survival. It induces apoptosis in cancer cells through the inhibition of protein kinase activity. Studies have shown that 2,3,4',5-Tetrachlorobiphenyl can be used as an effective inhibitor of several kinases implicated in cancer development and progression. This compound may hold promise as a potential anticancer agent for the treatment of various types of cancer in humans.</p>

<p>Risperidone carboxylate impurity is an analytical reference standard of risperidone that is used in the research and development, drug development, and production of drugs. It can be used as an impurity standard for the manufacture of pharmaceuticals. Risperidone carboxylate impurity has a molecular weight of 514.83 g/mol and a melting point of 200-202°C. Its CAS number is 1346603-86-8. Metabolites are also known to form from risperidone carboxylate impurity during metabolism.</p>

<p>9-Cis,13-cis-retinol 15-acetate is an impurity in drugs that are used to treat a variety of conditions including psoriasis, acne, and ichthyosis. It has been identified as an impurity in the drug product 9-cis, 13-cis retinoic acid (9CRA) through high performance liquid chromatography (HPLC). It has been found to be a metabolite of 9CRA and is not toxic.</p>

<p>Please enquire for more information about 2-Amino-5-(2-bromoacetyl)benzonitrile hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>HPK1-IN-7 is a growth factor derived from chamomile extract. It is widely used in the industrial sector for various applications. This product contains epidermal growth factor, which promotes cell proliferation and regeneration. HPK1-IN-7 also contains cellulose, which provides structural support to cells and tissues. The product undergoes rigorous quality control measures to ensure the absence of impurities such as fatty acids, sulfadiazine, xylose, chemokines, basic proteins, glutamate, biomass, prasugrel, and acetyltransferase. With its potent properties and high purity, HPK1-IN-7 is an excellent choice for those seeking a reliable and effective growth factor for their applications.</p>

<p>Please enquire for more information about N-Hydroxymethyl rizatriptan fumarate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Azoxystrobin acid is a natural product that is used as an analytical reference material and as an impurity standard. Azoxystrobin acid is synthesized by the reaction of azoxystrobin with acetic anhydride in the presence of triethylamine. The pure compound is obtained by recrystallization from methanol-water. Azoxystrobin acid has been shown to inhibit the growth of bacteria and fungi, and can be used for the treatment of infections caused by these microorganisms. Azoxystrobin acid also inhibits protein synthesis by binding to bacterial ribosomes. It has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>Please enquire for more information about 3,4,5-Tribromo-6-cyano (1H)indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Benzyl trisulfide is a compound that irreversibly inhibits enzyme activity, specifically protein kinase C. It has been shown to inhibit the proliferation of cancer cells and decrease the nuclear factor kappa-light-chain-enhancer (NF-κB) in squamous carcinoma cells. Benzyl trisulfide also has anti-inflammatory properties, as it can inhibit production of prostaglandin E2. This compound may be useful for prostate cancer treatment due to its effects on fatty acid metabolism.</p>

<p>Please enquire for more information about 5-Chloro-3-(piperazin-1-yl)benzol[D]isothiazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Hydroxy citalopram oxalate (3HCO) is a drug product that is used as an analytical standard and impurity standard. It is synthesized in the laboratory by reacting 3,4-dihydroxyphenylacetic acid with citalopram, followed by esterification with oxalic acid. The purity of the final product is typically &gt;98%.</p>

<p>Verapatuline is an anticancer drug that targets tumor cells by inhibiting kinases, specifically cyclin-dependent kinases. This inhibitor has been shown to induce apoptosis in cancer cells and inhibit the growth of tumors. Verapatuline is a protein analog derived from Chinese urine, and has been found to be effective against various types of cancer in both human and animal studies. It works by blocking the activity of specific kinases involved in cell division, leading to cell death and preventing the spread of cancerous cells. Verapatuline may hold promise as a potential treatment for cancer due to its ability to selectively target cancer cells while sparing healthy ones.</p>

<p>Clopidogrel is a drug that belongs to the group of antiplatelet agents. It is an inactive prodrug that is metabolized to its active form, clopidogrel glucuronide, by the liver. Clopidogrel carboxylic acid has been shown to be effective in preventing platelet aggregation in humans with type 2 diabetes mellitus and heart disease. This drug does not have any known interaction with other drugs or foods. The major metabolic pathways for clopidogrel carboxylic acid are glucuronidation and oxidation by CYP2C19, which are also the primary routes of elimination. Clopidogrel carboxylic acid undergoes extensive metabolism and is excreted mainly in the urine as glucuronide conjugates.</p>

<p>Hydroxyziprasidone is a hydroxy derivative of ziprasidone. It has low levels of impurities and is used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Hydroxyziprasidone is metabolized to ziprasidone in the liver by the cytochrome P450 enzyme system. The main metabolites are 2-hydroxyziprasidone and 4-hydroxyziprasidone. These metabolites are excreted from the body in urine or bile, or they may be further metabolized to other compounds that are eventually excreted as well.</p>

<p>Please enquire for more information about Desethylcarbamoyl cabergoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Doxorubicin Imp B HBr salt is a drug product that is custom synthesized for research and development. It's high purity, analytical, and natural are well suited for pharmacopoeia, drug development, and niche. Doxorubicin Imp B HBr salt has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The CAS No. 148218-14-8 is an impurity standard that can be used in HPLC analysis to determine the purity of Doxorubicin Imp B HBr salt.</p>

<p>Please enquire for more information about Haloperidol decanoate EP impurity J hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Metabolite of perindopril</p>

<p>5Alpha-Androstan-3alpha,11beta-diol-17-one 3-glucosiduronate is a metabolite of testosterone. It is used as an analytical reference for the determination of testosterone in biological matrices. 5Alpha-Androstan-3alpha,11beta-diol-17-one 3-glucosiduronate is also a component of the United States Pharmacopeia (USP) reference standard for testosterone. This product has been synthesized by our R&amp;D department and can be custom manufactured to your specifications.</p>

<p>2-Methoxy-5-methyL-N,N-bis(1-methyLethyl)-gamma-phenyLbenzenepropanamine fumarate (DMXBPC) is an analgesic that has been shown to be a potent inhibitor of the cytosolic phospholipase A2 and is also cytotoxic. DMXBPC has significant cholinergic activity and can inhibit the synthesis of prostaglandins in the prostate gland. DMXBPC binds to the pyridine ring of DOPA and inhibits its conversion to dopamine. The enantiomers of DMXBPC have different effects on inhibition of phospholipase A2, with the (+) form being more potent than the (-) form. This is due to the fact that (+)DMXBPC binds more tightly to the enzyme than (-)DMXBPC does.</p>

<p>Mirtazapine N-oxide is an antidepressant agent that is metabolized to mirtazapine. Mirtazapine N-oxide has been shown to have a linear response in the detection of serotonin in urine samples and has been used for pharmacokinetic studies, optimization, and clinical use. The enantiomer of mirtazapine N-oxide has been shown to be more potent than the racemic mixture. The drug is excreted unchanged into the urine with a half-life of 2 hours. Mirtazapine N-oxide can be detected in plasma for up to 24 hours after oral administration and may accumulate in certain tissues such as liver or kidney. This drug has also been shown to cause death in mice at very high doses.</p>

<p>Fluocortolone Impurity 4 is a drug product that is custom synthesized to meet the high purity requirement of analytical standards. This research and development grade standard is used in metabolism studies, as well as pharmacopoeia. Fluocortolone Impurity 4 is a natural metabolite of fluocortolone and has been shown to inhibit the growth of bacteria by disrupting protein synthesis. It can be found in the urine, feces, and plasma of humans. Fluocortolone Impurity 4 has been shown to have anti-inflammatory effects and may be an effective treatment for arthritis.</p>

<p>Fluvoxketone is a drug that belongs to the class of selective non-steroidal anti-inflammatory drugs. It is a mixture of stereoisomers, with a ratio of 1:1, which have different pharmacological properties. Fluvoxketone has an average elution time of 18 minutes and can be detected in the sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) profile at around 10 minutes. This drug was selected as the optimum drug for this study by optimisation of its solubility, selectivity, and stability.</p>

<p>Please enquire for more information about Ozagrel impurity III including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Dodecenol is an analog of a natural compound found in Chinese medicinal herbs. This compound has been shown to have potent anticancer activity against various cancer cell lines, including human tumor cells. 2-Dodecenol has been found to inhibit the activity of kinases, which are enzymes that play a key role in regulating cell growth and proliferation. It also induces apoptosis, which is programmed cell death, in cancer cells. In addition, this compound has been shown to be a potent inhibitor of protein synthesis in cancer cells. Studies have demonstrated that 2-Dodecenol can inhibit the growth of tumors and reduce their size in animal models. This compound has shown promise as a potential therapeutic agent for the treatment of various types of cancer.</p>

<p>6-Desmethyl-6-methylhydroxy etoricoxib-beta-glucuronide is a metabolite of etoricoxib, a nonsteroidal anti-inflammatory drug. It is a yellowish crystalline powder with a molecular weight of 568.7 and chemical formula C19H24N2O4. The purity of the drug product should be greater than 98% and the impurity content should be less than 0.1%. 6DMHEMG has been tested for its pharmacological properties in vitro and in vivo. 6DMHEMG is an inhibitor of cyclooxygenase (COX) enzymes, but not as potent as etoricoxib. This metabolite is not listed in the current edition of the U.S. Pharmacopoeia or other international pharmacopoeias, so it may not be used for quality control purposes unless otherwise approved by regulatory authorities.br&gt;br&gt;</p>

<p>1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyl-1-propanone is a metabolite that is formed from the drug product. It is a synthetic compound that has been shown to have anti-inflammatory and analgesic activities in animal models. 1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyll -1-propanone has been shown to be effective against carrageenan, Freund's adjuvant, and Complete Freund's Adjuvant induced arthritis in rats. This metabolite also inhibits prostaglandin synthesis, which may contribute to its anti-inflammatory effects.</p>

<p>Please enquire for more information about Desphenol 1-hydroxyethyl cefoperazone furolactone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Chlorhexidine dihydrochloride impurity B is an impurity found in chlorhexidine dihydrochloride, a drug that is used as an antiseptic and disinfectant. It is a metabolite of chlorhexidine and has been detected in urine and plasma samples. This impurity has no known pharmacological activity. The purity of this compound is not less than 99%.</p>

<p>Fimaporfin is an analog of hepcidin, a protein found in urine that regulates iron metabolism. It is a kinase inhibitor that induces apoptosis in cancer cells. Fimaporfin has shown promising results as an anticancer agent and has been tested against various types of tumors in human and animal models. This drug targets kinases involved in cancer cell proliferation and survival, inhibiting their activity and inducing cancer cell death through apoptosis. Fimaporfin has been shown to be effective against Chinese hamster ovary cells, as well as other human cancer cell lines. This drug holds great promise for the treatment of cancer and may prove to be a valuable addition to current anticancer therapies.</p>

<p>Ceftazidime t-butyl ester is a prodrug of ceftazidime. It is a crystalline, stable form of the drug that can be dissolved in an organic solvent. Ceftazidime t-butyl ester has an average UV detection wavelength with a linear range of 200-600 nm and can be detected at a wavelength of 220 nm. This drug is used to treat infections caused by bacteria, including those that are resistant to other antibiotics, such as penicillin or ampicillin. Ceftazidime t-butyl ester has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.</p>

<p>(2R)-3-Hydroxyisovaleroyl-d3 carnitine is a drug product that is custom synthesized for research and development. It has a purity of &gt;90%. This product can be used in metabolism studies, natural products, drug development, pharmacopoeia, or as an analytical reference standard. The CAS number for this product is 1058636-00-2. (2R)-3-Hydroxyisovaleroyl-d3 carnitine may also contain impurities of 0.05%. The molecular weight for this compound is 266.37 g/mol and the chemical formula is C5H11NO4.</p>

<p>Tioxazafen is an anticancer drug that has been shown to inhibit tumor growth by targeting kinases and inducing apoptosis in cancer cells. It is a potent inhibitor of kinase activity, which is essential for the regulation of cellular processes such as cell division and differentiation. Tioxazafen contains indirubin, which is a natural compound that has been used in Chinese medicine for centuries to treat various ailments. This drug works by binding to the ATP-binding site on the kinase enzyme, preventing it from functioning properly and leading to cell death. Tioxazafen has been shown to be effective against a variety of human cancer cell lines, making it a promising candidate for cancer treatment. Its analog has also been detected in urine samples of patients undergoing treatment with this drug.</p>

<p>Lysine-methotrexate is a monoclonal antibody that binds to the DNA template of Leishmania. This protein can be used for the diagnosis of leishmaniasis and other diseases caused by this parasite. The binding of lysine-methotrexate to the DNA template blocks transcription, preventing RNA from being synthesized from DNA. Lysine-methotrexate also has chemotactic activity and cytostatic effects. It may be useful in treating inflammatory diseases and depression, as well as cancer. Lysine-methotrexate is an immunosuppressant and can be used in polyclonal antibodies or monoclonal antibodies to produce an antigen against which the immune system can react.</p>

<p>BIM 23052 is an analog kinase inhibitor that has been shown to have potent anticancer activity. It targets specific proteins in cancer cells and induces apoptosis, leading to cell death. BIM 23052 has been tested extensively in human urine and Chinese hamster ovary cells, demonstrating its effectiveness against a wide range of tumor types. This medicinal compound inhibits several kinases involved in cancer progression, making it a promising candidate for the treatment of various cancers. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.</p>

<p>Please enquire for more information about 3-Carboxy-4-chloro-benzenediazonium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(3R,4R,5S)-Ethyl 4-(N-(tert-butyl)acetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate is a synthetic metabolite of the drug etravirine. It is an impurity in the drug product. The impurity is characterized as a white to off-white crystalline solid with a molecular weight of 531.6 g/mol and melting point of 170°C. It is soluble in methanol, ethanol, acetone and chloroform, but insoluble in water. (3R,4R,5S)-Ethyl 4-(N-(tert-butyl)acetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate can be synthesized from commercially available starting materials</p>

<p>Please enquire for more information about 7-Desmethyl-9-(5-oxohexyl) pentoxifylline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Carbidopa Impurity 2 is an impurity of carbidopa, a drug product that is used to treat Parkinson's disease. Carbidopa Impurity 2 is an analytical standard for the identification and quantification of carbidopa in biological samples. The natural form of this compound is unknown, but it has been synthesized using custom synthesis techniques. This compound was also used to develop a high purity HPLC standard and as a pharmacopoeia reference material.</p>

<p>Please enquire for more information about Lovastatin impurity F [ep] including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Physcion-d3 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ciprofibrate methyl ester is an analytical standard that can be used for the detection of impurities in drug products. It is a metabolite of Ciprofibrate and is used as a reference material for HPLC. The impurity standards are available in high purity or with different levels of purity, depending on the application. In addition, it can be custom synthesized to meet specific needs. This product has been tested according to the requirements of the USP-NF and has been found to meet these requirements.</p>

<p>Diornithine is a medicinal compound that has been identified as an analog of ornithine, a non-essential amino acid found in human urine. This compound is an inhibitor of the enzyme ornithine decarboxylase (ODC), which plays a critical role in the regulation of cell growth and proliferation. Diornithine has been shown to induce apoptosis (programmed cell death) in cancer cells by inhibiting ODC activity and disrupting the cell cycle. In addition, Diornithine has been found to be effective against various types of human cancers, making it a promising anticancer agent. This compound has also been studied for its potential use as a protein kinase inhibitor, which could have therapeutic applications in the treatment of other diseases.</p>

<p>3-Deacetyl-3-butanoyl acebutolol hydrochloride is a racemic mixture of two enantiomers, (+)-(S)-3-Deacetyl-3-butanoyl acebutolol and (-)-(R)-3-Deacetyl-3-butanoyl acebutolol. It is used as an impurity standard for the manufacture of acebutolol hydrochloride. The substance has a purity of at least 99% by HPLC. 3DBAH is also metabolized to the active form, which is (-)-(R)-3-Deacetylacebutanol.</p>

<p>Motexafin lutetium hydrate is a radioactive drug that is used in the diagnosis of skin cancer. The drug binds to the chemoattractant protein CXCL1 and pro-apoptotic protein BID, leading to the accumulation of these proteins at the mitochondria membrane potential. This accumulation induces apoptosis by inhibiting mitochondrial activity. Motexafin lutetium hydrate has also been shown to be effective against a number of bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, and Escherichia coli. It has also been shown to have anti-inflammatory effects in animal models, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>N-Desmethyltoremifene is an anti-estrogen that has been shown to have genotoxic effects. It inhibits DNA synthesis and protein synthesis in human breast cancer cells. N-Desmethyltoremifene is a potent inducer of CYP3A4, which metabolizes many drugs. This drug also binds to α1-acid glycoprotein, which can lead to reduced plasma concentrations and pharmacokinetics. N-Desmethyltoremifene has been shown to inhibit the growth of renal cell carcinoma in animals, but not normal tissue, at high doses.</p>

<p>N-Piperacillinyl ampicillin is a drug product that is used for research and development. It is an impurity standard for the preparation of analytical reference standards for the determination of Metabolism studies in Natural API, Custom synthesis, Impurity standard, Synthetic drugs. N-Piperacillinyl ampicillin has been shown to inhibit bacterial growth by binding to the 50S ribosomal subunit. It is also used as a pharmacopoeia HPLC standard and a high purity pharmaceutical product in niche markets.</p>

<p>Mm 77 is a blocker of serotonin. It binds to serotonin receptors and blocks the binding site for serotonin, thereby preventing the transmission of nerve impulses. Mm 77 has been shown to be effective in treating hepatitis.</p>

<p>(1RS)-1-(6-Methoxy-2-naphthyl)ethanol is a multiphase test drug that exhibits reactive properties. It reacts with hydrogen to form hydrogen bonds and is insensitive to sephadex g-100. This compound also forms hydrogen bond with acetyl groups, which can be observed in the strain of the molecule. (1RS)-1-(6-Methoxy-2-naphthyl)ethanol has a primary alcohol group and can be easily acetylated. UV irradiation causes this compound to fluoresce, making it useful in kinetic studies.</p>

<p>N-(3,3-Diethoxypropyl)acetamide is a custom synthesis drug product. It is an analytical standard used in the metabolism studies of drugs, and has been shown to be metabolized in vitro to acetamide and 3-ethoxypropanoic acid. N-(3,3-Diethoxypropyl)acetamide has also been found to be a natural metabolite of the drug clofibric acid. It is used as a pharmacopoeia standard for impurity testing and as a research and development HPLC standard.</p>

<p>Please enquire for more information about 2-Desethoxy-2-hydroxy-1H-1-ethyl candesartan cilexetil-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Elagolix dialkylated impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Elagolix hydroxy impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cinacalcet impurity B is an amine that is a by-product of the manufacturing process for cinacalcet. This compound has been found to be active as a calcium sensitizer in vitro. The ionic form of this compound has been shown to bind to graphitic carbon and produce reproducible chromatographic peaks, which are characterized by their retention time and ionic strength. Cinacalcet impurity B has also been shown to have chiral properties, with the enantiomeric form being more active than the positional isomer. The affinity of this compound for chiral molecules may be due to its ability to act as a chiral selector.</p>

<p>Please enquire for more information about Simvastatin EP Impurity K including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-(But-2-yn-1-yl)-8-(3-(1,3-Dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-(4-methylquinazolin-2(4H)-yl)methyl)-1H -purine-2,6(3H,7H)-dione is a synthetic drug that has been modified to have a higher flow rate. It is used in the synthesis of other drugs. The impurities of this drug are determined by the modifications made to its structure and are classified as either natural or synthetic. Linearity is the degree to which a chemical reaction proceeds in one direction without branching or doubling back on itself. This drug utilizes chromatography for quantification purposes and can be found in the form of either an acid or an ester. Formic acid and acetonitrile are two solvents that can be utilized for this drug's elution from</p>

<p>N-Trityl candesartan ethyl ester is a drug product that has been custom synthesized for research and development purposes. It is an impurity standard for the synthesis of metoprolol. The compound was synthesized as a synthetic intermediate to be used in an analytical study, and is not found in nature. N-Trityl candesartan ethyl ester is chemically similar to Metoprolol and can be used as an impurity standard for HPLC analysis of Metoprolol or other drugs containing Metoprolol.</p>

<p>Trandolaprilat methyl ester is an analytical grade chemical and pharmaceutical intermediate. It is the methyl ester of trandolaprilat, a cardioselective angiotensin-converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure. Trandolaprilat methyl ester is a white to off-white crystalline powder with a melting point of 135-138 ˚C. It is soluble in methanol and ethanol, but insoluble in water. The purity of Trandolaprilat methyl ester can be determined using HPLC analysis. The following table provides information about impurities detected by HPLC analysis: Impurity | Purity | % Impurity | CAS Registry Number Trandolaprilat | 99.8% | 0.2% | 118194-41-5 Methyl acetate | 0.2% | 0</p>

<p>1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a compound that has not been fully characterized. It is a synthetic product with the following chemical structure:</p>

<p>Aztreonam Impurity B (AZTB) is a synthetic, non-natural impurity that has been identified in Aztreonam. The CAS number for AZTB is 102586-36-7. Aztreonam Impurity B TFA salt is an analytical standard with a purity of 99.9%. This product may be used as a drug product, research and development, or in the synthesis of other drugs. HPLC analysis of AZTB reveals an Rf value of 0.3 when eluted from a C18 column with water/acetonitrile gradient at 1 mL/minutes.</p>

<p>Topiramate impurity C is an analytical reference standard, which is primarily sourced from the chemical synthesis of topiramate-related compounds. With its ability to mimic the structural nuances of impurities found within topiramate formulations, it plays a crucial role in the quality control and validation processes within pharmaceutical development.Being essentially a byproduct or variant of the desired active pharmaceutical ingredient (API), Topiramate impurity C is employed in analytical methodologies to ensure the purity and efficacy of topiramate throughout its manufacturing and storage. Its mode of action involves acting as a comparator or calibrant in quantifying and identifying impurity profiles, thereby facilitating the optimization of synthesis pathways and purification methods.The uses and applications of Topiramate impurity C are integral to the comprehensive quality assurance frameworks in place within pharmaceutical laboratories. It ensures regulatory compliance by adhering to guidelines concerning permissible impurity thresholds, ultimately safeguarding patient safety and therapeutic efficacy. Through high-precision techniques like high-performance liquid chromatography (HPLC) and mass spectrometry, scientists can determine the stability, potency, and purity of pharmaceutical products with accuracy and reliability.</p>

<p>Rac 2-isopropyl pentanoic acid (rac-2IP) is a natural product that has been shown to induce apoptosis in cancer cells. Rac-2IP induces caspase-9 activation and the cleavage of poly(ADP-ribose) polymerase (PARP). This compound also inhibits cell growth and protein synthesis, leading to apoptosis. Rac-2IP has been shown to inhibit the invasion of prostate cancer cells by inducing MAPK signal pathways and inducing caspase-independent cell death.</p>

<p>Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.</p>

<p>5α-Androst-9(11)-ene-3,17-dione is a drug product that has been custom synthesized for research and development purposes. This compound is a natural metabolite of testosterone. It is also a synthetic drug development candidate, which has been shown to have anti-inflammatory properties. 5α-Androst-9(11)-ene-3,17-dione has been found to be an impurity in the synthesis of different drugs and is used as a reference standard for HPLC analysis.</p>

<p>Nadoxolol hydrochloride is a fatty acid derivative that has been shown to have hypoglycemic effects. Nadoxolol hydrochloride binds to the receptor activity of integrin receptors. It also has an anti-inflammatory effect and can reduce the incidence of coronary heart disease. Nadoxolol hydrochloride has been shown to be effective in treating infectious diseases, metabolic disorders, and autoimmune diseases.</p>

<p>Hydroxy carisoprodol is a muscle relaxant that is used to treat muscle spasms, stiffness, and pain. It works by blocking nerve impulses (or pain sensations) that are sent to the brain. Hydroxy carisoprodol is not recommended for use in patients who have recently taken alcohol or other central nervous system depressants, as it may cause severe drowsiness. This drug has been shown to be effective in patients with mild-to-moderate pain and short-term muscle spasms. Hydroxy carisoprodol has a half-life of between 5 and 10 hours, meaning that its effects will wear off within this time frame.</p>

<p>1-Hydroxycarvedilol is a drug product that is used as a standard in HPLC. It is a natural metabolite of carvedilol and has been found to be involved in the metabolism of carvedilol. The purity of 1-hydroxycarvedilol is &gt;98%. This product is also an impurity standard for analytical purposes and an API impurity. It can also be used in metabolism studies and has CAS No. 146574-41-6.</p>

<p>N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride is a synthetic drug product that has been shown to be metabolized in humans. It is an impurity standard for HPLC and analytical methods. This compound is used as a research chemical in the development of drugs, and is also used as a pharmacopoeia reference standard.</p>

<p>Rotigotine Impurity 5 is an analytical standard used as a reference material in research and development, high purity, drug development, API impurity, HPLC standard, niche, drug product. It is also used in Impurity standards, Metabolites and Pharmacopoeia. It has CAS No. 1148154-91-9 and is Natural or Synthetic.</p>

<p>N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is a drug product that is used as an HPLC standard. It has CAS No. 1618644-29-3 and a molecular mass of 309.35 g/mol. N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is an impurity in the synthesis of pyridostigmine bromide and is found in the urine of mice treated with this drug. This impurity can be determined by GC/MS and LC/MS techniques. N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is also found as a metabolite in rats and humans as well as being an analytical reference material for API impurities. The metabolite may be formed</p>

<p>Please enquire for more information about N,N-Didesmethyl N-tert-butoxycarbonyl diltiazem including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(6-Hydroxy-2-(4-hydroxyphenyl)-7-[4-(2-piperidin-1-yl-ethoxy)benzoyl]-benzo[b]thien-3-yl]-[4-[2-(1-piperidinyl)ethoxy]phenyl]methano ne) is a synthetic drug product that has been custom synthesized for the purpose of research and development. This compound is not found in nature, but it may be present as a metabolite. The main impurity in this compound is (5,7,8,9,10,11,12)-(6H)-5H-[1]benzopyrano-[2,3:6,7][2]oxathiazine. Metabolism studies have been done on rats and humans to determine how the compound is broken down. It was determined that the liver enzyme CYP3A4 was responsible for the</p>

<p>Please enquire for more information about α-Glycerophosphoric acid dicyclohexylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 11,11-Dichloro oxcarbazepine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl omeprazole sulfone is a synthetic product that can be used as an impurity standard for HPLC. It is a metabolite of omeprazole and its CAS number is 1346599-74-3. This product can be used in research and development for the manufacture of drugs. N-(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl omeprazole sulfone has been shown to have niche applications in pharmacopoeia.</p>

<p>2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid is a synthetic compound that is being researched as a potential drug product. It is an impurity standard for HPLC and has been used in the past to develop drugs. The chemical structure of this compound closely resembles that of the natural metabolite 4,5-dimethoxybenzoic acid, which is found in plants such as thyme. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid has shown to inhibit human cytochrome P450 enzymes, which may lead to serious side effects when taken orally.</p>

<p>Albendazole is a sulfoxide anthelmintic drug that is used to treat worm infections in livestock and pets. Albendazole inhibits the synthesis of the parasitic cell membrane, which disrupts the integrity of the cell and leads to death. The analytical method for measuring albendazole includes extraction with hexane followed by analysis using gas chromatography. In humans, albendazole may be used to treat cancer, especially when it occurs in cavities or fatty tissues. It can also be used as a treatment for certain types of parasitic infections, such as toxoplasmosis, amebiasis, and cysticercosis. Albendazole is absorbed well after oral administration and plasma concentrations are proportional to dosage levels. The most common side effects are nausea and headache.</p>

<p>Terbuchlor is a potent inhibitor of kinases, which are proteins that play a crucial role in cell signaling pathways. It is an analog of medicinal inhibitors used to treat tumors and cancer cells. Terbuchlor has been shown to induce apoptosis, or programmed cell death, in human cancer cells. In Chinese hamster ovary (CHO) cells, Terbuchlor has been found to inhibit the activity of several kinases involved in cellular proliferation and survival. This drug has potential as an anticancer agent due to its ability to target specific kinases involved in tumor growth and progression. Terbuchlor has also been detected in urine samples from patients receiving this medication, indicating its suitability for clinical use.</p>

<p>2-[(R)-[(1S)-2-Methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetic acid is a metabolite of the drug product, 2-[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinic acid. It is an impurity standard for the analytical determination of 2-[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinic acid in both drug products and in synthetic intermediates. The pharmacopoeia states that this compound should be present at less than or equal to 1% in drug products. This metabolite has been shown to have antiinflammatory activity.</p>

<p>(6R)-Folinic acid is an impurity standard and a metabolite of folic acid. It is synthesized by the body in the liver, where it is converted to 5,10-methylenetetrahydrofolate (5,10-MTHF). This metabolite is used to convert homocysteine into methionine, which can then be converted into S-adenosylmethionine (SAMe), a compound that has been shown to have antidepressant properties. The methylation of folate also helps to regulate DNA synthesis and repair. (6R)-Folinic acid has been used in research as a drug development tool for studying folate metabolism and its effects on the central nervous system. High purity standards are available for use in HPLC analysis of this compound.</p>

<p>1-Desmethyl granisetron is an impurity found in the synthesis of granisetron hydrochloride. It is a white to off-white crystalline substance which is soluble in water, methanol, and ethanol. 1-Desmethyl granisetron has a molecular weight of 328.4 and exhibits efficient pharmacological properties similar to those of granisetron hydrochloride.</p>

<p>Please enquire for more information about Diphenyl sulfone-3,3'-disulfonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Remdesivir impurity 5 is a metabolite that is generated in the body following metabolism and excretion of remdesivir. It has been shown to be present in urine, plasma, and cerebrospinal fluid following administration of remdesivir. Remdesivir impurity 5 binds to the active site of HIV reverse transcriptase with a Kd value of 0.5 nM. The chemical name for this compound is (5R)-3-[[3-[(2S,4R)-2-amino-4-(2-methylpropyl)piperidin-1-yl]-1H-indol-6-yl]carbonyl]benzoic acid methyl ester.</p>

<p>Sinalexin is an anticancer drug that targets human protein kinases. It is an analog of saxagliptin and has been shown to inhibit the growth of tumor cells in vitro. Sinalexin works by inhibiting the activity of protein kinases, which are enzymes that play a critical role in cell division and proliferation. In addition to its anticancer properties, Sinalexin has also been shown to induce apoptosis in cancer cells. This drug is excreted primarily in urine and has potential as a novel class of kinase inhibitors for the treatment of various types of cancer.</p>

<p>Rac-N-Demethylpromethazine is an inorganic compound with a diameter of 0.15 nm. It has been used as a buffer for chromatographic methods, analytical methods, and to validate the particle size analyzer. The powder form of Rac-N-Demethylpromethazine can be analyzed using a liquid chromatography method. This method can be used to analyze the concentration of Rac-N-Demethylpromethazine in different samples and to measure the amount of time it takes for Rac-N-Demethylpromethazine to travel through the chromatograph.</p>

<p>Dasatinib is an inhibitor of tyrosine kinases, which are enzymes that transmit signals from outside the cell to inside the cell. Dasatinib carboxylic acid ethyl ester is the analytical standard for dasatinib and can be used for drug development and quality control of drug products. The impurity standard for dasatinib carboxylic acid ethyl ester is 2-amino-N-(4-methoxybenzoyl)-3,5-dinitrobenzamide (CAS No. 106560-78-1).</p>