APIs para pesquisa e impurezas

<p>3-[2-[(5-Ethyl-2-pyridinyl)ethoxy]phenyl] Pioglitazone Impurity is a drug product that is used for analytical purposes and as a research and development standard. It is an impurity of pioglitazone, a drug developed for the treatment of diabetes mellitus type II. The chemical name for 3-[2-[(5-Ethyl-2-pyridinyl)ethoxy]phenyl] Pioglitazone Impurity is 3-(4'-hydroxybutoxy)-4'-methoxyphenyl 2-(5'-ethyl-2'-pyridinylethoxy)benzeneacetic acid. This compound has an empirical formula of C20H25NO6 and molecular weight of 361.39 g/mol. The CAS number is 952187-99-4.</p>

<p>N-(2,2,2-Trichloroethoxy)carbonyl] bisnor-(cis)-tilidine is an analog of dabigatran that has been shown to be a potent inhibitor of human kinases. It has demonstrated anticancer activity by inducing apoptosis in cancer cells and inhibiting tumor growth. This compound has been found in urine samples from Chinese patients with cancer, suggesting that it may have potential as an anticancer agent. N-(2,2,2-Trichloroethoxy)carbonyl] bisnor-(cis)-tilidine acts as a protein kinase inhibitor and may be useful in the development of new cancer therapies. Its mechanism of action is thought to involve the inhibition of various kinases involved in cell proliferation and survival pathways. Overall, this compound holds great promise for its potential use in the treatment of cancer.</p>

<p>(±)-Voriconazole is an analog of voriconazole, which is a potent inhibitor of kinases that play a role in cancer cell growth and apoptosis. It has been shown to be effective against tumors in human and Chinese hamster cells. (±)-Voriconazole also inhibits angiotensin-converting enzyme (ACE), which may play a role in its anticancer activity. This drug has been found to have a low potential for toxicity and is well-tolerated by patients. It is excreted primarily through the urine and has been shown to be effective as an inhibitor of multiple kinases involved in cancer progression.</p>

<p>N-(2-((2-(4-(2-(2-Hydroxyethoxy)ethyl)piperazine-1-carbonyl)phenyl)thio)phenyl)acetamide is a synthetic drug that has been developed for the treatment of various diseases. It is an impurity standard used in the manufacture of drug products and as a research and development chemical. Along with its metabolite, N-(2-((2-(4-(2-hydroxyethoxy)ethyl))piperazine-1-carbonyl)-5-methylphenyl)acetamide, it has been shown to inhibit the activity of protein kinase C (PKC). N-(2-((2-(4 (2 (2 -hydroxyethoxy)ethyl))piperazine-1 -carbonyl)-5 methylphenyl)acetamide has also been shown to have antiinflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>Please enquire for more information about 9-Hydroxy propantheline bromide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Haloperidol decanoate EP impurity K hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-[Ethyl-(2-pyridyl-5-ethyl) pioglitazone] is a drug that belongs to the class of tetracyclic compounds. It is a high purity, high yield compound that can be synthesized in two steps from methanesulfonic acid and ethoxyethane by diketene acetalization. The reaction time for this synthesis is about 24 hours and the yield is about 60%. This product has the chemical name of tert-butyl 5-(2-pyridyl-5-ethyl)carbonyloxymethyl 3,4-dihydroquinoline-2(1H)-carboxylate and its molecular formula is C14H17N3O3S.</p>

<p>5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane is an analytical standard used in HPLC and GC. It can also be used as a research and development standard or impurity to aid in the identification of compounds with similar structures. 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane has a purity of 99% and a melting point of 80°C. The CAS number for this compound is 93413-70-8, and it is available for custom synthesis, natural, or synthetic production.</p>

<p>3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a drug product that can be used as an analytical reference standard. It is a synthetic compound that is not found in nature and has CAS number 1199589-74-6. This compound has been synthesized by custom synthesis and it is an impurity standard for HPLC analysis. 3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3 -yl)-1 -piperidinyl]ethyl]-6,7,8,9 -tetrahydro - 2 methyl - 4H - pyrido[1,2 -a]p</p>

<p>2-Azahypoxanthine sodium salt is a compound with a unique set of characteristics. It has been extensively studied and its properties have been thoroughly analyzed. The mass spectrum of 2-Azahypoxanthine sodium salt reveals its molecular structure and provides valuable information about its composition.</p>

<p>3-O-Desethyl-5-O-desmethyl amlodipine is a drug product that can be used as an analytical reference standard. It is metabolized in vivo to form 5-O-desmethyl amlodipine, which is the active form of this drug. 3-O-Desethyl-5-O-desmethyl amlodipine is also an impurity in the drug product Amlodipine besylate and its CAS number is 1821498-25-2. The synthetic route for this compound starts with the reaction of 2,3,4,6 trichlorobenzeneethanol with sodium hydroxide followed by hydrogenation of the intermediate to yield 3-(2,6 dichlorophenyl) propanoic acid. This acid was then reacted with methylamine to yield 3-(2,6 dichlorophenyl)-N-[(methylamino) methyl]propionamide.</p>

<p>Please enquire for more information about 2,2',3,4,4',5,6,6'-Octabromodiphenyl ether including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Anhydrovinblastine N’B-oxide sulfate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>25-Hydroxy vitamin D3 3-sulfate sodium salt is a unique compound that exhibits various characteristics and functions. It is derived from dimethyl fumarate, tenofovir, dopamine, and other substances. This compound acts as a steroid and plays a crucial role in maintaining the body's overall health.</p>

<p>Ethyl 3,6-dioxocyclohexa-1,4-diene-1-sulfonate is an analog that has shown potential as an anticancer agent. It works by inhibiting kinases that are involved in cancer cell growth and proliferation. Studies have shown that this compound induces apoptosis in human tumor cells, making it a promising candidate for cancer treatment. Ethyl 3,6-dioxocyclohexa-1,4-diene-1-sulfonate has also been found to be a potent inhibitor of protein kinase D (PKD), which plays a key role in cancer cell survival and proliferation. This compound has been compared to the well-known kinase inhibitor saxagliptin and found to be more effective at inhibiting PKD activity. Additionally, Chinese hamster ovary cells treated with Ethyl 3,6-dioxocyclohexa-1,4-diene-1-sulfonate showed reduced levels of urinary ex</p>

<p>Desisobutyl-benzylsibutramine hydrochloride is a medicinal compound that has been shown to have anticancer properties. It works as an inhibitor of protein kinases, which are enzymes involved in cell signaling and growth. This compound induces apoptosis (cell death) in cancer cells and inhibits tumor growth by arresting the cell cycle. Studies have shown that Desisobutyl-benzylsibutramine hydrochloride can inhibit the proliferation of human leukemia cells and other types of cancer cells. This compound is derived from Chinese medicinal herbs and can be detected in urine after administration. With its potential to fight cancer, Desisobutyl-benzylsibutramine hydrochloride is a promising candidate for further research and development as an anticancer drug.</p>

<p>Dapoxetine N-oxide is a pharmaceutical agent that inhibits serotonin reuptake and has been shown to be effective in the treatment of premature ejaculation. It is a metabolite of dapoxetine, which is an antidepressant drug. Dapoxetine N-oxide has a terminal half-life of about 10 hours, which is shorter than that of its parent compound. Dapoxetine N-oxide also has a lower carcinogenic potential than its parent compound. This agent can inhibit the activity of rat liver microsomes, as well as human liver microsomes at high concentrations. It also has no effect on plasma concentrations at low doses, but does show dose proportionality at higher doses. Dapoxetine N-oxide also does not have any impurities or other drugs added to it.</p>

<p>3-(Dimethylamino)-1-(2-thienyl)propan-1-ol is an organic compound that is used as a chiral building block in the synthesis of drugs. It is not currently used in any known drug, but it has been shown to be racemized at high temperatures. 3-(Dimethylamino)-1-(2-thienyl)propan-1-ol is also a byproduct of pollution and can be found in the environment where it may be degraded by bacteria.</p>

<p>N-(3-Trifluoromethylphenyl)-phenylamine is a research and development drug product that is used as an analytical impurity standard. It has a CAS number of 101-23-5 and is classified under the trade name 3TFPPA. The chemical formula for N-(3-Trifluoromethylphenyl)-phenylamine is C12H8F3NO. This compound can be synthesized from phenylamine, 3-trifluoromethylaniline, and hydrochloric acid. The molecular weight of this compound is 197.19 g/mol, which falls within the range of 195 to 200 g/mol. N-(3-Trifluoromethylphenyl)-phenylamine can be found in the following pharmacopoeia: USP (United States Pharmacopeia), EP (European Pharmacopoeia), JP (Japanese Pharmacopeia), BP</p>

<p>Diclofenac dimer impurity is a synthetic impurity that is used as a research and development, impurity standard, custom synthesis, drug product, and analytical standard. It is a high purity, CAS No. 1609187-30-5, pharmacopoeia (USP), Drug development (DSD), Metabolite (MET), niche, analytical standard. Diclofenac dimer impurity is a natural metabolite of diclofenac in humans and other animals. The chemical name for the metabolite is 2-(dichlorophenyl) propionic acid or 2-[2-chloro-4-(2,2-dichlorovinyl)phenoxy]propanoic acid. Diclofenac dimer impurity may be synthesized by reacting diclofenac with paraformaldehyde followed by hydrolysis with sodium hydroxide or potassium hydroxide. HPLC analysis</p>

<p>Delta 2 Cefdinir is a cephalosporin antibiotic used for the treatment of respiratory tract infections and skin infections. The drug product is an analytical standard that has been custom synthesized for metabolism studies. It is also used as an impurity standard for synthesis in research and development, as well as for HPLC analysis. Delta 2 Cefdinir is a high-purity, pharmacopoeia grade API with a purity of &gt;98% and contains no detectable levels of natural impurities.</p>

<p>Please enquire for more information about (R,R,S,S)-Cisatracurium dibesylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Azathioprine impurity B is an analog of the immunosuppressant drug azathioprine. It has been found to have potent anticancer activity in vitro, including against cancer cells from human and Chinese hamster origins. Azathioprine impurity B has been shown to inhibit kinases, which are enzymes that play a key role in cell signaling pathways that regulate cell growth and survival. This inhibition induces apoptosis, or programmed cell death, in cancer cells. Azathioprine impurity B is also a potent inhibitor of nifedipine-sensitive calcium channels, which may contribute to its anticancer activity by disrupting intracellular calcium signaling.</p>

<p>Please enquire for more information about Levothyroxine EP impurity B including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-Methylhexyl orlistat decyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The impurity is a natural product and an API impurity. The impurity is synthesized by the rearrangement of (E/Z)-FK-506 26,28-allylic ester. This impurity has been shown to be present in drug products at concentrations up to 0.0025% w/w. It is found in analytical samples at concentrations up to 0.02% w/w, which may be due to its use as a HPLC standard. The impurity has been studied for metabolism in rats and rabbits and is not metabolized by microsomal enzymes or conjugated with glucuronic acid. The compound has also been shown to have anti-inflammatory properties in mice models and has no cardiotoxic effects on Balb/c mice.</p>

<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>

<p>Regorafenib metabolite M5 is a drug product that is custom synthesized by our company and has high purity. It can be used in metabolism studies, drug development, and pharmacopoeia due to its natural origin. It is also a synthetic compound that can be used as an impurity standard or research and development standard in HPLC.</p>

<p>Methyl 4-methyl-3-[2-(propylamino)acetamido]thiophene-2-carboxylate is an impurity that can be found in the drug product. It is a metabolite of clozapine, which is used to treat schizophrenia and other psychiatric disorders. This impurity can be detected by HPLC or LC/MS analysis and quantified using a calibration curve generated from standards. Methyl 4-methyl-3-[2-(propylamino)acetamido]thiophene-2-carboxylate may also be found in the urine as an indicator of clozapine use.</p>

<p>M,M-Quaterphenyl is a low energy fluorescent molecule that emits light in the near ultraviolet region of the electromagnetic spectrum. It is chemically stable and has a high quantum yield. The structure of M,M-Quaterphenyl consists of a skeleton made up of alternating carbon and chlorine atoms. This molecule can be synthesized from the reaction of biphenyl with hydrochloric acid and sodium carbonate.</p>

<p>Warfarin is a clinically used drug that is an anticoagulant and has been shown to have anticancer activity. Warfarin has been shown to inhibit the synthesis of unsaturated ketones by carbonyl reduction and asymmetric synthesis. It also inhibits the growth of cancer cells in animals and human liver cells. Warfarin reduces the production of coagulation factors II, VII, IX, and X by inhibiting protein synthesis in the liver. The anticoagulant effect of warfarin is due to inhibition of the synthesis of vitamin K-dependent clotting factors II, VII, IX, and X. Warfarin also binds to a cytosolic protein called matrix metalloproteinase-9 (MMP-9) which inhibits its proteolytic activity.</p>

<p>(4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2-pyrrolidinone is a synthetic, impurity standard and research and development compound. (4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2pyrrolidinone is used as an analytical reference in the synthesis of other compounds. It is also used in drug development for the treatment of tuberculosis. This product has a high purity level and is pharmacopoeia grade.</p>

<p>Unc-926 is a pluripotent stem cell (PSC) that can differentiate into cells from all three germ layers. Unc-926 cells have been shown to be glucose-dependent and utilize the mitochondrial respiratory chain for respiration. These cells are capable of differentiating into insulin-producing beta cells and pancreatic islet cells, which can be used in the treatment of diabetes.</p>

<p>5-Ethyl-5-phenyl-2-(1-phenylpropyl)dihydropyrimidine-4,6(1H,5H)-dione is an impurity in the drug product of the drug 5-[3-(3,4-dihydroisoquinolin-2(1H)-yl)propoxy]-2,2'-bis[N-(2-hydroxyethyl)]ethaneamine. It is an analytical standard for HPLC and can be used as a pharmacopoeia or custom synthesis. It is also a metabolite of the drug 5-[3-(3,4-dihydroisoquinolin-2(1H)-yl)propoxy]-2,2'-bis[N-(2-hydroxyethyl)]ethaneamine.</p>

<p>4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one (4AAT) is an analytical chemical that is used for research and development purposes. 4AAT is a metabolite of the antibiotic ampicillin and has been identified as an impurity in the drug product. It can be synthesized from 2-(4'-chlorophenyl)benzaldehyde, 3,5'-di-O-(4'-chlorobenzoyl)-2',3'-dideoxyribose and sodium azide in a two step process with 98% purity. 4AATs are also found to be present in natural products such as honey or sugar cane juice.</p>

<p>2-(4′-Chloro-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-yl)-3-hydroxynaphthalene-1,4-dione is a research and development impurity standard. It is a synthetic compound that is used as an impurity standard for the manufacture of drug product. 2-(4′-Chloro-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-yl)-3-hydroxynaphthalene-1,4-dione has high purity and can be used in pharmacopoeia and drug development studies to measure metabolism. 2-(4′-Chloro-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-yl)-3 -hydroxynaphthalene -1</p>

<p>Captopril EP Impurity H is a drug product that is used as an analytical reference standard. It is not intended for administration to humans or animals. Captopril EP Impurity H is manufactured by the same process as Captopril, but with a different impurity profile. The purity of this product is 99.5% at 25°C, and it has an impurity profile of less than 0.5%. This product is also known as 4-Amino-N-(2,6-dichlorophenyl)benzenesulfonamide and has CAS No. 205521-07-9.</p>

<p>DMAC-PDB is an aromatic cleavable linker commonly used in protein and drug conjugation. It enables controlled release of payloads under specific chemical conditions.</p>

<p>4-Desmethyl-4-ethylimidazolyl nilotinib is a synthetic drug product that is custom-synthesized for research and development purposes. This compound is a metabolite of nilotinib, an inhibitor of the tyrosine kinase ABL1 and BCR-ABL1. 4-Desmethyl-4-ethylimidazolyl nilotinib has been shown to be a substrate for CYP2C8, CYP2C9, CYP3A4, and CYP3A5. It has also been found to be an impurity in API standards of nilotinib.</p>

<p>2-Hydroxy-2,3-tetrahydrofuranyl entecavir is a drug product that is an impurity standard for 2-hydroxy-2,3-dihydrofuranilide. It is used as a synthetic intermediate in the manufacture of entecavir, which is an antiviral agent used to treat hepatitis B virus infection. 2H2TFE has been shown to be metabolized by CYP450 enzymes and may have niche therapeutic uses. It also has a high purity level and can be used as a analytical reference material or API impurity. CAS No. 1984788-96-6</p>

<p>Propoxyphenyl homohydroxysildenafil is a preparative mass spectrometric analysis of the metabolite of sildenafil, which is a phosphodiesterase type 5 inhibitor. It has been shown to increase the flow rate in rats with an experimental pulmonary hypertension. The product ions of propoxyphenyl homohydroxysildenafil are m/z 409.3, 417.2, and 419.2, and its pharmacological study has been conducted on tadalafil and isobutyl.</p>

<p>Please enquire for more information about Des(methylpiperazinyl) imatinib dimer piperazinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>NPS-ALX-4A is a drug, which has been shown to have cognition-enhancing effects in mice. It is a 5-HT6 receptor antagonist and can be used as an animal model for human cognitive disorders. NPS-ALX-4A was administered orally to control mice and the animals were tested for learning and memory. The study showed that NPS-ALX-4A improved spatial memory in the mouse model. This drug has not been tested on humans, but it has shown cognitive benefits in the mouse model with no significant side effects.</p>

<p>(3α)-Allopregnanolone sulfate is a medicinal compound with potential anticancer properties. It is an analog of the natural hormone allopregnanolone and has been shown to inhibit kinases involved in cancer cell proliferation and survival. This compound induces apoptosis, or programmed cell death, in cancer cells by targeting proteins that regulate cell growth and division. (3α)-Allopregnanolone sulfate has been studied as a potential inhibitor of tumor growth in human cancer cells and has shown promising results. It can be detected in urine samples and has also been used in Chinese traditional medicine for its medicinal properties.</p>

<p>Cefixime EP Impurity C disodium is an impurity in the drug Cefixime EP. It is a by-product of the synthesis process, which can be removed by a purification process. This product is an analytical standard and is used for qualitative analysis in HPLC. It is also used as a research and development standard for drug development. This product has been classified as a niche impurity since it only occurs at trace levels in the drug product, but it may have pharmacological relevance to some patients. This impurity can be synthesized from natural or synthetic sources and is available for custom synthesis to meet specific customer needs.</p>

<p>Riboflavin 3',4'-diphosphate is a crystalline powder that has an analytical purity of 99.9%. This compound is used as a research and development standard for HPLC, as well as an impurity standard for riboflavin. It is also used in the synthesis of drugs and pharmaceuticals, such as antibiotics and antiviral agents. Riboflavin 3',4'-diphosphate can be synthesized from natural or synthetic sources.</p>

<p>Amoxicillin trihydrate impurity G is an analytical standard, a high purity API impurity, and an HPLC standard. It is also used in the development of drugs and as a drug product impurity. Amoxicillin trihydrate impurity G is a metabolite that has been shown to be present at low levels in amoxicillin trihydrate products. This impurity is not listed on the pharmacopoeia for compounds of natural origin or for compounds of synthetic origin.</p>

<p>Sulfo EGS is a potent analog that has shown promising anticancer activity in various human cancer cell lines. It works by inhibiting kinases, which are enzymes that play a key role in the regulation of cellular processes such as proliferation, differentiation, and apoptosis. Sulfo EGS has been found to be particularly effective against Chinese hamster ovary cells and tumor cells from medicinal plants. This inhibitor also shows potential for use in the development of kinase inhibitors for cancer therapy. In addition, Sulfo EGS is commonly used as a cross-linking reagent to covalently link proteins or protein complexes in urine or other biological samples for further analysis. Overall, Sulfo EGS is an important tool for cancer research and drug development.</p>

<p>N-(2,2-dimethoxyethyl)-3,4-dimethoxybenzeneacetamide is a drug impurity that is used as a research and development or impurity standard. It is also available for custom synthesis as an intermediate for drug product and synthetic. This product has high purity, with a purity of 99%. The CAS number for this compound is 73954-34-4. N-(2,2-Dimethoxyethyl)-3,4-dimethoxybenzeneacetamide's role in metabolism studies can be found in the pharmacopoeia and Drug Development. Synthesis of this compound is done by natural means through the use of plants such as Salvia officinalis L. (sage).</p>

<p>(trans)-4-Propyl-1-methyl-L-proline is a synthetic compound that has been used in the past as an impurity standard in the synthesis of several drugs, including metaxalone and aminopyrine. It is also found to have pharmacological effects on its own and was used as a drug product for the treatment of rheumatoid arthritis. (trans)-4-Propyl-1-methyl-L-proline is not listed in any pharmacopoeia or international list of approved drugs.</p>

<p>2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid hydrobromide is a drug product that is Custom synthesized. It has a high purity and analytical quality. Metabolism studies have been conducted on this compound. Natural and synthetic sources are available for this compound. It is found in the Drug Development section of the pharmacopoeia. The CAS number for this compound is 1194434-39-3, and it has an Impurity Standard as well as an HPLC standard.</p>

<p>Methisosildenafil is a chemical compound that belongs to the group of phosphodiesterase type-5 inhibitors. It is an analog of sildenafil and is used for the treatment of erectile dysfunction (ED). Methisosildenafil has been shown to be effective in animal models of pulmonary hypertension. It also inhibits the production of myeloid-derived suppressor cells, which are responsible for suppressing the immune system. Methisosildenafil has been found to be safe and well-tolerated for use as a pharmaceutical preparation in humans.</p>

<p>Estriol trisulfate-ammonium salt is a potent anticancer agent that has been shown to inhibit tumor growth and induce apoptosis in cancer cells. This compound is derived from urine and acts as an inhibitor of kinases, which are proteins involved in the regulation of cell growth and division. Estriol trisulfate-ammonium salt is an analog of quetiapine, a drug used to treat schizophrenia and bipolar disorder. It has been found to be effective against various types of cancer in Chinese hamster ovary cells and human tumor cell lines. The compound works by inhibiting the activity of specific kinases involved in cancer cell proliferation, making it a promising candidate for targeted cancer therapy.</p>

<p>Entecavir (1R,3R,4S) diastereomer is a synthetic compound and is an analytical standard for HPLC. This product is an impurity of the drug Entecavir. The impurity is characterized by a retention time of 17.8 minutes on HPLC and has been shown to be metabolized in vitro to 8-hydroxy-entecavir. The purity of this product is 98% with a CAS number of 1367369-78-5.</p>

<p>5-Oxo atorvastatin is an impurity standard for atorvastatin. It is a synthetic metabolite that has been observed in the urine of patients receiving atorvastatin. 5-Oxo atorvastatin can be used as a reference compound to calibrate HPLC measurements and as an analytical standard in pharmacopoeia testing.</p>

<p>Please enquire for more information about (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-vinyl-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Descyclopropyl-2-oxopropyl prasugrel is a metabolite of the prodrug prasugrel. It is a synthetic compound that has been shown to have pharmacological activity similar to its parent drug. Descyclopropyl-2-oxopropyl prasugrel has a purity of &gt;98% and is available as an API standard in impurity grade and as custom synthesis. The chemical name for descyclopropyl-2-oxopropyl prasugrel is 2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2- yl)butoxy]-N-(3S)-(3aR*,8aS*)-octahydroindole-1,3(2H)-dione.</p>

<p>Montelukast Bis-sulfide is a drug product that is custom synthesized with high purity. It has been studied for its metabolism, analytical properties, and natural sources. The metabolite of montelukast bis-sulfide has been extensively researched for pharmacopoeia as well as for drug development. Montelukast bis-sulfide is a synthetic compound that is not found in nature, but it has niche applications in research and development. CAS No.: 1242260-05-4</p>

<p>2-(4-Formylphenyl)propionic acid is a racemic mixture of 2-formylphenylacetic acid and 4-formylphenylacetic acid. This compound is used in the treatment of bacterial infections and inflammation. It is an organic solution that can be injected, administered orally, or applied topically. The 2-(4-formylphenyl)propionic acid has been shown to have anti-inflammatory properties, but also has side effects such as skin irritation when it is applied topically. This drug can also cause nausea, vomiting, and diarrhea when administered orally.</p>

<p>2-(Dibenzylamino)-3',4'-dihydroxy-acetophenone is a drug product that is used as an analytical reference standard for the metabolism studies of acetaminophen. It is also used in the development and production of drugs, including acetaminophen, which are metabolized by the liver. 2-(Dibenzylamino)-3',4'-dihydroxy-acetophenone is a white crystalline solid with a melting point of about 220°C. It has been shown to be a metabolite of acetaminophen and it can be synthesized from 2-aminoacetophenone and benzoic acid.</p>

<p>Desisopropyl disopyramide oxalate is a racemic mixture of the enantiomers, (+)-desisopropyl disopyramide and (-)-desisopropyl disopyramide. It is an anticholinergic drug that can be used to treat chronic depression. Desisopropyl disopyramide binds to two different sites on the enzyme p-450 and inhibits the metabolism of drugs such as benzodiazepines and tricyclic antidepressants. Desisopropyl disopyramide has been shown to have an inhibitory effect on activated muscarinic receptors in animal models, but not in humans. This drug also has anti-cholinergic effects and is used for the treatment of pediatric patients with spasticity.</p>

<p>Docetaxel Impurity D is an impurity found in the formulation of Docetaxel, a drug used to treat cancer. The impurity is a 10-deacetylated form of docetaxel that has been shown to have chiral properties. Docetaxel Impurity D can be separated from the active ingredient through chromatographic techniques and quantified by high-performance liquid chromatography. It has been found to be present in all batches of docetaxel tested, but at different concentrations.</p>

<p>Fluocortolone Impurity 5 is a drug product that is custom synthesized for research and development purposes. It has high purity and analytical standards, as well as metabolite and impurity standards. Fluocortolone Impurity 5 can be used in pharmacopoeia, natural products research, drug development, and other niche applications. Fluocortolone Impurity 5 is a synthetic compound that is not found in nature.</p>

<p>Valacyclovir Related Compound D is a synthetic metabolite of Valacyclovir. It is the primary metabolite of Valacyclovir, which has been shown to inhibit the activity of bacterial DNA polymerase. Valacyclovir Related Compound D is an impurity standard for valacyclovir and can be synthesized in quantities as per customer requirement.</p>

<p>Lumiflavin-3-acetic acid is a dietary supplement that has been shown to enhance the rate of carboxylation of tryptophan by its conversion to 5-hydroxytryptophan. This compound is a flavin and can be used as an electron acceptor in techniques involving carbanion formation. Lumiflavin-3-acetic acid is not sensitive to diketones, making it an insensitive reagent for the detection of this class of compounds. It also has a constant kinetic constant and can be used as a supplement in uncatalyzed reactions due to its lack of reactivity with proton transfer. This molecule also has nuclear polarization properties, which allow it to be used in nuclear magnetic resonance (NMR) spectroscopy.</p>

<p>Aminopentamide sulfate is a pharmaceutical dosage form that is a polymeric matrix containing glycol ether, fatty acid ester, and glycol ester. It is used as a local anesthetic to numb the skin and other tissues. Aminopentamide sulfate can be administered topically or by injection into the body. It has been shown to have therapeutic effects on animals with pain-related conditions such as arthritis and neuropathy. The intramolecular hydrogen bonds in aminopentamide sulfate are thought to be formed between the carbonyl group of atropine sulfate and the hydroxyl groups of benzimidazole derivatives. These functional groups form hydrogen bonds with fatty alcohols in the matrix, which may help stabilize it.</p>

<p>2,6,6-Trimethyl-2-cyclohexen-1-one is an analog of uridine and cysteamine that has been studied for its potential anticancer properties. It has been shown to induce apoptosis in cancer cells and inhibit tumor growth in both human and Chinese hamster ovary cell lines. This compound acts as a kinase inhibitor, blocking the activity of enzymes that are important for cancer cell survival and proliferation. Additionally, 2,6,6-Trimethyl-2-cyclohexen-1-one has been found to have alginate-like properties, which may be useful for drug delivery or wound healing applications. Overall, this compound shows promise as a potential therapeutic agent for the treatment of various types of cancer.</p>

<p>7-O-(Triethylsilyl) paclitaxel is a synthetic Taxol analog. It is manufactured by custom synthesis and purified by HPLC to be used as an analytical standard for the determination of natural Taxol impurities in drug products.</p>

<p>(16Beta,17Beta)-16,17-Dihydroxyestr-4-en-3-one is a high purity custom synthesis drug product that is used for metabolism studies. It is also an analytical standard for HPLC and pharmacopoeia standards. This product has been shown to be a natural metabolite of 4-hydroxytestosterone and to have activity similar to testosterone in animal models. (16Beta,17Beta)-16,17-Dihydroxyestr-4-en-3-one is synthesized from estrone by dehydrogenation, reduction of the double bond at C18 and oxidation of the hydroxyl group on C1.</p>

<p>(-)-Bornyl ferulate is a natural compound, specifically a type of ferulic acid ester, which is a secondary metabolite found in certain plants. Its source is primarily the essential oils and resins of various coniferous species, where it contributes to the plant's defense mechanisms. The mode of action of (-)-Bornyl ferulate involves its ability to scavenge free radicals, thus exhibiting antioxidant activity. It also modulates inflammatory pathways, suggesting possible anti-inflammatory effects.</p>

<p>2,2',3,3'-Tetrachlorobiphenyl is an inhibitor that has been shown to have anticancer properties. It inhibits the growth of tumor cells by blocking the activity of protein kinases, which are enzymes that regulate cell division and proliferation. This compound has been tested in Chinese hamster ovary cells and has been found to induce apoptosis in cancer cells. Additionally, 2,2',3,3'-Tetrachlorobiphenyl has analog inhibitors that have been tested in human urine samples and have shown potential as anticancer agents. These analogs inhibit cyclin-dependent kinases (CDKs), which play a crucial role in regulating the cell cycle. The inhibition of CDKs leads to the suppression of cancer cell growth and division, making this compound a promising candidate for future cancer treatments.</p>

<p>(E)-4-Alloxycarboxyl tamoxifen is a synthetic metabolite of tamoxifen. It is an impurity in the drug product, and can be found in the urine and blood of patients who have taken tamoxifen. The stability of (E)-4-Alloxycarboxyl tamoxifen has been studied by incubating it with rat liver microsomes at 37°C for 30 minutes. Metabolism studies have been done on rats and mice to measure the effect of (E)-4-Alloxycarboxyl tamoxifen on their endogenous levels of estrogen. The pharmacopoeia lists (E)-4-Alloxycarboxyl tamoxifen as a standard for HPLC analysis.</p>

<p>4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol is a synthetic compound that is used in the development of pharmaceutical drugs. It is used as an analytical standard for HPLC and is available as a new drug product. 4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol has been shown to be metabolized by CYP 450 enzymes and to be an impurity in API production. 4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol is also found in natural products such as plant leaves and bark.</p>

<p>N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide is a metabolite that is formed when the drug product, ticagrelor, undergoes metabolism in the liver. Ticagrelor is a prodrug that requires conversion to its active form, which is N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide, before it can be used as a platelet inhibitor and antiplatelet agent for the prevention of thrombotic events such as heart attack and stroke. It has been shown to have an excellent stability profile and high purity when produced by HPLC or synthesized using the latest methodology under GMP conditions.</p>

<p>N-Boc-N-desethyl acetildenafil is a synthetic drug product that is used as an analytical standard in metabolite studies. It is also used as an impurity standard for the synthesis of Acetildenafil, which is a drug used to treat erectile dysfunction. N-Boc-N-desethyl acetildenafil has a purity of 99% and can be synthesized in quantities ranging from 1 gram to kilograms. This product's CAS number is 1246820-46-1.br&gt;<br>br&gt;<br>N-Boc-N-desethyl acetildenafil has not been evaluated by the FDA and is not intended for human or veterinary use.</p>

<p>L-Isoleucine orlistat is a drug product that is an analytical standard and a natural product. It is used in research and development for the study of drug metabolism, and as an impurity standard for synthetic L-isoleucine. L-Isoleucine orlistat has CAS number 1072902-75-0 and Impurity Standard Number (ISN) 910.<br>L-Isoleucine orlistat is not a registered active pharmaceutical ingredient (API). It can be custom synthesized to meet the requirements of a particular application, such as high purity, pharmacopoeia grade, or USP HPLC grade.</p>

<p>Ros 234 is a dioxalate salt of rosiglitazone, and is an anti-cancer agent that inhibits the growth of cancer cells. Ros 234 has been shown to inhibit inflammatory conditions such as asthma, rheumatoid arthritis, and colitis. It also modulates immune and autoimmune responses.</p>

<p>Deschloro amlodipine is a drug that is used for the treatment of high blood pressure. It belongs to a group of drugs called calcium channel blockers. Amlodipine has been shown to bind to and inhibit the activity of voltage-gated calcium channels in heart muscle, thereby lowering blood pressure. Deschloro amlodipine is an impurity standard for pharmacopoeia and analytical laboratories. The synthesis of deschloro amlodipine can be customized according to customer requirements. This product will be shipped as soon as possible after purchase.br&gt; br&gt; Desloro amlodipine is metabolized by cytochrome P450 enzymes, including CYP3A4, CYP2C9, and CYP2D6, which are found in the liver and intestines. These enzymes convert desloro amlodipine into two metabolites: 4-hydroxyamlodipine and 4</p>

<p>Fluocortolone Impurity 1 is a metabolite of fluocortolone. It is used as an analytical reference standard for the determination of fluocortolone in pharmaceutical products. Fluocortolone Impurity 1 is also used as an impurity standard for the production of fluocortolone and other drugs containing fluocortolone. Fluocortolone Impurity 1 is listed in the U.S. Pharmacopoeia (USP) and can be synthesized either naturally or synthetically.</p>

<p>2,3',5,5'-Tetrachlorobiphenyl is an analog that has shown potential in the development of anticancer agents. Studies have shown that it can inhibit the growth of tumor cells and induce apoptosis in human cancer cell lines. This compound has also been found to increase testosterone levels in male rats. Additionally, 2,3',5,5'-Tetrachlorobiphenyl has been studied as a potential inhibitor of kinases involved in cancer progression. Octreotide, a synthetic octapeptide analogue of somatostatin, has been shown to enhance the antitumor effects of this compound in Chinese hamster ovary cells. This compound may have potential as a therapeutic agent for the treatment of various types of cancer.</p>

<p>Frovatriptan is a drug used to treat migraine attacks. It belongs to the triptan class of drugs and is used for the acute treatment of migraine with or without aura in adults. Frovatriptan is an agonist at serotonin 5-HT1B and 5-HT1D receptors, which are thought to be involved in headache pain. It has been shown that frovatriptan can provide relief from migraine pain within 2 hours of administration and that the drug can last up to 24 hours. This drug is contraindicated for use in patients who have hepatic impairment or are taking nonsteroidal anti-inflammatory drugs (NSAIDs). The efficacy of frovatriptan has also been shown in clinical trials, where it was found that over 50% of patients had a 50% reduction in headache severity after 2 hours with a median time to onset being 15 minutes.</p>

<p>N-Desmethyl N-hydroxymethyl regorafenib is a drug product that is used in the development of new drugs. It is a chemical intermediate that has been synthesized to produce a desired metabolite. The molecule contains two methyl groups, two hydroxyl groups, and one carboxylic acid group on the aromatic ring. This product has been purified to high purity by analytical methods.</p>

<p>Please enquire for more information about Colterol-d9 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Desloratadine N-carboxylic acid methyl ester is an impurity in the drug product, Desloratadine. The chemical name for this impurity is desloratadine N-carboxylic acid methyl ester. This product can be found in the Metabolism studies section of our catalog under natural products. Desloratadine N-carboxylic acid methyl ester is a custom synthesis with a purity level of 99%. It is used as an analytical standard and has been shown to have similar retention times as the CAS No. 165740-03-4 reference standard.</p>

<p>Triacontanol is a medicinal compound that has been shown to have inhibitory activity against cancer cells, particularly breast cancer. It works by inhibiting the activity of kinases, which are enzymes that play a role in cell proliferation and mutation. Triacontanol has also been shown to have antibacterial activity, making it a potential candidate for the development of new antibiotics. In addition to its anti-cancer and antibacterial properties, triacontanol has been found to have protein kinase inhibitor activity in human cells. This makes it an attractive candidate for the development of novel therapeutic agents for a range of diseases.</p>

<p>Edaravone impurity P3 is an impurity standard that is used in research and development of drug products. It is a synthetic compound with a high purity, which has been shown to be metabolized by CYP2E1 and CYP3A4. Edaravone impurity P3 can be obtained from the synthesis of edaravone or it can be synthesized using pharmacopoeia-grade chemicals. This compound has a CAS number of 1323485-71-7. The analytical retention time for Edaravone impurity P3 is 8.6 minutes and its HPLC purity grade is 99%.</p>

<p>ITE analog is an anticancer agent that works by inhibiting the activity of certain kinases in cancer cells. This inhibitor has been shown to induce apoptosis and inhibit tumor growth in both human and Chinese hamster ovary cell lines. ITE analog is a protein toxin that can be found in urine, but the synthetic analog is more potent and selective than the natural compound. This analog has been tested against a variety of kinases, including those involved in cancer cell proliferation, and has shown promising results as a potential treatment for cancer. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.</p>

<p>Please enquire for more information about (Arg)9 (TFA) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit</p>