APIs para pesquisa e impurezas
Os Ingredientes Farmacêuticos Ativos (APIs) são as substâncias nos medicamentos responsáveis por seus efeitos terapêuticos. Nesta seção, você encontrará uma ampla variedade de APIs destinados a uso em pesquisa. Esses compostos são essenciais para o desenvolvimento, teste e validação de novas formulações farmacêuticas. Na CymitQuimica, oferecemos APIs de alta qualidade para apoiar a pesquisa em descoberta e desenvolvimento de medicamentos.
Subcategorias de "APIs para pesquisa e impurezas"
- Aminoácidos e Derivados(12.318 produtos)
- Antraquinonas e Derivados(402 produtos)
- Derivados de Benzimidazol e Imidazol(10.390 produtos)
- Derivados das Benzodiazepinas(326 produtos)
- Carboidratos e Glicoconjugados(5.044 produtos)
- Ésteres e Derivados(42.242 produtos)
- Ácidos Graxos e Derivados Lipídicos(32.374 produtos)
- Flavonoides e Polifenóis(17.073 produtos)
- Radicais Livres e Agentes Oxidantes/Redutores(211 produtos)
- Cetonas e Derivados(2.399 produtos)
- Antibióticos Naturais e Semissintéticos(6.324 produtos)
- Nitrilas e Derivados Ciano(3.068 produtos)
- Nitrosaminas e Derivados(55 produtos)
- Nucleosídeos e Nucleotídeos(3.445 produtos)
- Fosfatos e Fosfonatos Orgânicos(1.194 produtos)
- Sulfonatos e Sulfatos Orgânicos(10.419 produtos)
- Compostos Organometálicos(4.417 produtos)
- Outros(6.269 produtos)
- Peptídeos e Proteínas(3.132 produtos)
- Polímeros e Derivados(99 produtos)
- Derivados de Purinas e Pirimidinas(8.898 produtos)
- Derivados de Quinazolina e Quinolina(65.683 produtos)
- Quinonas e Derivados(24.341 produtos)
- Sais e Derivados de API(81.254 produtos)
- Esteroides e Derivados(4.923 produtos)
- Sulfonamidas e Derivados(2.564 produtos)
- Terpenoides e Derivados(3.835 produtos)
- Tiazolidinedionas e Tiopiranos(2.753 produtos)
- Compostos β-Adrenérgicos(227 produtos)
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Foram encontrados 58629 produtos de "APIs para pesquisa e impurezas"
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Endo-cis-lurasidone hydrochloride
CAS:Produto ControladoEndo-cis-lurasidone hydrochloride is a synthetic, high purity, analytical standard material. It is an impurity in the drug product, Lurasidone hydrochloride. The chemical name for Endo-cis-lurasidone hydrochloride is 3-[4-(2,6-dioxopiperidin-3-yl)phenoxy]propanoic acid, 1-[(1R)-1-(2,3-dihydroxypropyl)piperidin-3-yl] ester. The CAS number for Endo-cis-lurasidone hydrochloride is 1318074-20-2.Fórmula:C28H37ClN4O2SPureza:Min. 95%Peso molecular:529.1 g/molClobetasol propionate EP Impurity F
CAS:Produto ControladoPlease enquire for more information about Clobetasol propionate EP Impurity F including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C22H27FO4Pureza:Min. 95%Peso molecular:374.45 g/molGW300657X
CAS:GW300657X is an indirubin analog that has been shown to act as a potent inhibitor of tumor growth in Chinese hamster ovary cells. It has also demonstrated anticancer activity in human cancer cell lines by inducing apoptosis, or programmed cell death. GW300657X targets kinases and proteins involved in the regulation of cell division and proliferation, making it a promising candidate for cancer treatment. This compound can be detected in urine after administration, indicating its potential for clinical use. As a kinase inhibitor, GW300657X shows great potential in the development of new cancer therapies.Fórmula:C21H18N6O4SPureza:Min. 95%Peso molecular:450.5 g/molDe(2,3-dihydroxy) nadolol hydrochloride
CAS:De(2,3-dihydroxy) nadolol hydrochloride is a drug product that is custom synthesized to meet the needs of customers. The high purity and analytical quality of this drug makes it a good candidate for use in metabolism studies and drug development. De(2,3-dihydroxy) nadolol hydrochloride is a natural metabolite that has been found to be present in human urine as well as many other animal species. It is also an impurity standard for HPLC analysis. Metabolites of de(2,3-dihydroxy) nadolol hydrochloride have been identified in rat liver microsomes and these metabolites have been shown to inhibit the activity of the enzyme benzoate-CoA ligase (BCL), which is involved in the biosynthesis of cholesterol.Fórmula:C17H28ClNO2Pureza:Min. 95%Peso molecular:313.9 g/mol5-Eicosene
CAS:5-Eicosene is an analog that has been shown to have potent anticancer properties. It acts as an inhibitor of various protein kinases, including cyclin-dependent kinases, which are essential for cancer cell growth and division. Studies have demonstrated that 5-Eicosene induces apoptosis in Chinese hamster ovary cells and human cancer cells, suggesting its potential as an effective anticancer agent. Additionally, this compound inhibits the activity of certain urinary protein kinases, which may be valuable in the diagnosis and treatment of cancer. Overall, 5-Eicosene shows promise as a potent inhibitor with therapeutic potential against various types of cancer.Fórmula:C20H40Pureza:Min. 95%Peso molecular:280.5 g/molAmlodipine diethyl ester
CAS:Amlodipine diethyl ester is a synthetic drug that belongs to the group of calcium channel blockers. It is used for the treatment of high blood pressure, angina, and other cardiovascular diseases. Amlodipine diethyl ester is metabolized by hydrolysis to amlodipine, which has been shown to have an anti-inflammatory effect. The pharmacopoeia grade of amlodipine diethyl ester is a high purity drug product with a purity level of 98%. The CAS No. 140171-65-9 is a drug product that can be custom synthesized for research and development purposes or for use in the manufacture of pharmaceuticals.Fórmula:C21H27ClN2O5Pureza:Min. 95%Peso molecular:422.9 g/molL-733,060 Hydrochloride
CAS:L-733,060 Hydrochloride is a drug product that was custom synthesized for the purpose of research and development. It is a white to off-white crystalline powder with a melting point of 178.5°C. The purity of L-733,060 Hydrochloride is greater than or equal to 98% by analytical HPLC. L-733,060 Hydrochloride has been studied in metabolism studies and has been shown to be metabolized by cytochrome P450 enzymes, oxidative metabolites, hydrolysis by esterases, glutathione reductase, or conjugation with glucuronic acid. It also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
Fórmula:C20H20ClF6NOPureza:Min. 95%Peso molecular:439.8 g/mol4-Bromo-2-cyclobutylthiazole
CAS:Please enquire for more information about 4-Bromo-2-cyclobutylthiazole including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C7H8BrNSPureza:Min. 95%Peso molecular:218.12 g/molDiploicin
CAS:Diploicin is a potent anticancer drug that inhibits the growth of human tumors by targeting kinases. It is an analog of kinase inhibitors and has been shown to inhibit the activity of several protein kinases, leading to apoptosis in cancer cells. Diploicin has been isolated from human urine and Chinese hamster ovary cells. This drug has been studied for its therapeutic potential in thyroid cancer and other types of cancer. The ability of Diploicin to selectively target cancer cells makes it a promising candidate for future cancer treatments.Fórmula:C16H10Cl4O5Pureza:Min. 95%Peso molecular:424.1 g/mol4-Desmethyl-4-ethylimidazolyl nilotinib
CAS:4-Desmethyl-4-ethylimidazolyl nilotinib is a synthetic drug product that is custom-synthesized for research and development purposes. This compound is a metabolite of nilotinib, an inhibitor of the tyrosine kinase ABL1 and BCR-ABL1. 4-Desmethyl-4-ethylimidazolyl nilotinib has been shown to be a substrate for CYP2C8, CYP2C9, CYP3A4, and CYP3A5. It has also been found to be an impurity in API standards of nilotinib.Fórmula:C29H24F3N7OPureza:Min. 95%Peso molecular:543.50 g/molN-tert-Butyloxycarbonyl hydroxy brimonidine
CAS:Please enquire for more information about N-tert-Butyloxycarbonyl hydroxy brimonidine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C16H20BrN5O3Pureza:Min. 95%Peso molecular:410.27 g/molN-[2-[(1S)-5-Bromo-2,3-dihydro-6-(2-propen-1-yloxy)-1H-inden-1-yl]ethyl]propanamide
CAS:N-[2-[(1S)-5-Bromo-2,3-dihydro-6-(2-propen-1-yloxy)-1H-inden-1-yl]ethyl]propanamide is a synthetic compound that has been used as an analytical standard for HPLC. It has also been used in the development of drugs to treat cancer. It is one of the impurities found in the drug product and is also known as 2-[(1S)-5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(propenyloxy)indenyl]acetic acid. CAS No. 196597-85-0Fórmula:C17H22BrNO2Pureza:Min. 95%Peso molecular:352.3 g/molThymonin
CAS:Thymonin is an analog of the thyroid hormone that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in cancer cell growth and proliferation. Thymonin induces apoptosis, or programmed cell death, in cancer cells, making it an effective treatment option for various types of tumors. This protein-based substance is derived from Chinese urine and has been extensively studied for its potential as an inhibitor of human kinases. Thymonin has shown promising results in preclinical studies as a potential therapeutic agent for cancer treatment. Its ability to selectively target cancer cells while leaving healthy cells unharmed makes it a promising candidate for future cancer therapies.Fórmula:C18H16O8Pureza:Min. 95%Peso molecular:360.3 g/molPregnane
CAS:Produto ControladoPregnane is an analog of progesterone that has been identified as a potential anticancer agent. It has been shown to have potent inhibitory effects on various cancer cells by blocking the activity of kinases, which are enzymes that regulate cell growth and division. Pregnane induces apoptosis in cancer cells by activating proteins that trigger programmed cell death. This compound also acts as a cyclin-dependent kinase inhibitor, which prevents the progression of the cell cycle and inhibits tumor growth. Pregnane has been detected in human urine and Chinese medicinal herbs, indicating its natural occurrence in biological systems. Its potential as a therapeutic agent against cancer is currently being investigated.Fórmula:C21H36Pureza:Min. 95%Peso molecular:288.5 g/mol(3R)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,3,5-trifluorophenyl)-1-butanone
CAS:Please enquire for more information about (3R)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,3,5-trifluorophenyl)-1-butanone including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C16H15F6N5OPureza:Min. 95%Peso molecular:407.31 g/mol[4-[(2,5-Diamino-6-chloropyrimidin-4-yl)amino]cyclopent-2-en-1-yl]methanol
CAS:[4-[(2,5-Diamino-6-chloropyrimidin-4-yl)amino]cyclopent-2-en-1-yl]methanol is a drug product that is used as an analytical standard in the pharmaceutical and natural products industries. It has been shown to be metabolized by cytochrome P450 enzymes and glutathione reductase. The chemical name for this compound is 2,5 diamino 6 chloropyrimidine 4 yl cyclopentanamine. CAS No. 122624-77-5Fórmula:C10H14ClN5OPureza:Min. 95%Peso molecular:255.7 g/mol3-Hydroxy deoxy dihydro artemisinin
CAS:3-Hydroxy deoxy dihydro artemisinin is a drug product that is an analytical standard for the determination of artemisinin in natural and synthetic samples. It is a metabolite of artemisinin, which is a natural compound extracted from Artemisia annua L. (Asteraceae). 3-Hydroxy deoxy dihydro artemisinin is also an impurity found in commercial preparations of artemisinins. 3-Hydroxy deoxy dihydroartemisinin has been used as an API impurity standard, and has been synthesized as part of drug development research and development. The purity of this substance was determined by HPLC analysis, and it complies with the pharmacopoeia requirements.Fórmula:C15H24O5Pureza:Min. 95%Peso molecular:284.35 g/mol3-Desmethyl-3-(5-oxohexyl) pentoxifylline
CAS:Produto ControladoPlease enquire for more information about 3-Desmethyl-3-(5-oxohexyl) pentoxifylline including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C18H26N4O4Pureza:Min. 95%Peso molecular:362.4 g/mol6’-Hydroxy-amiodarone hydrochloride
CAS:Please enquire for more information about 6’-Hydroxy-amiodarone hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C25H29I2NO4Pureza:Min. 95%Peso molecular:661.3 g/molNP-AHD-13C3
CAS:Please enquire for more information about NP-AHD-13C3 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C10H8N4O4Pureza:Min. 95%Peso molecular:251.17 g/molPantoprazole impurity
CAS:Pantoprazole is a proton pump inhibitor. It is used in the treatment of gastroesophageal reflux disease and other conditions involving excessive stomach acid production. The chemical name for Pantoprazole impurity is (E)-1-(4-chlorophenyl)ethyl-3-[(pyrrolidin-2-yl)oxy]propanediol. This substance is an enantiomer of pantoprazole, which has been determined to be inactive. Pantoprazole impurity can be identified by its melting point, crystallizing habit, and optical rotation. Active carbon filtration can be used to remove this substance from the final product.Fórmula:C24H24F2N4O5SPureza:Min. 95%Peso molecular:518.53 g/mol(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-{[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl} acetamide dihydrochloride - >80%, Mixture of Diastereomers
(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl} acetamide dihydrochloride is a drug product with purity of >80%. It is a mixture of diastereomers. The impurities are not detected by HPLC. This compound is used in the development of drugs. Its metabolite is also available to purchase.Fórmula:C13H15N5O4S2·2HClPureza:Min. 95%Peso molecular:442.34 g/molClarithromycin (9E)-O-Methyloxime
CAS:Clarithromycin (9E)-O-Methyloxime is an analytical standard for Clarithromycin. It is a metabolite of Clarithromycin and has been shown to be a potent inhibitor of cytochrome P450 3A4 in human liver microsomes. Clarithromycin (9E)-O-Methyloxime is also an impurity in the drug product, which is used to treat bacterial infections.Fórmula:C39H72N2O13Pureza:Min. 95%Peso molecular:776.99 g/molEnniatin B4
CAS:Enniatin B4 is a potent inhibitor of cancer cells that has been shown to disrupt the cell cycle and induce apoptosis in breast cancer cell lines. This compound is derived from Chinese medicine and is a protein that specifically targets tumor cells, making it an effective anticancer agent. Enniatin B4 has also been found to be an inhibitor of leukemia cells and has shown activity against aryl hydrocarbon receptor (AhR)-dependent cancers. In human studies, this compound has demonstrated promising results as a potential treatment for various types of cancer due to its ability to selectively target cancer cells while leaving healthy cells unharmed.Fórmula:C34H59N3O9Pureza:Min. 95%Peso molecular:653.8 g/molN-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium
CAS:Produto ControladoPlease enquire for more information about N-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C8H6D3NO5S•NaPureza:Min. 95%Peso molecular:257.24 g/molCetirizine impurity C
CAS:Cetirizine impurity C is a potential impurity of cetirizine. It is used in the synthesis of cetirizine and as a drug substance. Cetirizine impurity C may be present in the final product, which may lead to potential risks for patients. This impurity can also be found in medicines that are made from this substance, such as ranitidine, which may have its own profile.Fórmula:C21H25ClN2O3Pureza:Min. 95%Peso molecular:388.89 g/molCelosin J
CAS:Celosin J is a potent kinase inhibitor that has been extensively studied for its anticancer properties. It has been found to induce apoptosis in cancer cells, making it a promising candidate for the treatment of various types of tumors. Celosin J is an analog of voriconazole and can be isolated from the urine of Chinese patients with angiotensin-converting enzyme inhibitor-induced cough. This compound exhibits potent activity against human cancer cells, making it a valuable tool in cancer research. Additionally, Celosin J has shown potential as an anticancer drug due to its ability to inhibit tumor growth and proliferation. Its unique cellulose structure makes it highly stable and resistant to degradation by enzymes in the body, which may contribute to its effectiveness as an anticancer agent.Fórmula:C58H90O28Pureza:Min. 95%Peso molecular:1,235.3 g/molMercaptopurine impurity standard
CAS:Mercaptopurine impurity standard is a drug product that is used as an analytical reference standard in the development of drugs. Mercaptopurine impurity standard is a natural metabolite of 6-mercaptopurine, which is used to treat leukemia and other forms of cancer. It has been shown to have an anti-inflammatory effect, but this has not been confirmed. Mercaptopurine impurity standard is a synthetic compound that is made synthetically for use as an impurity standard. It has also been shown to be metabolized by cytochrome P450 enzymes, glutathione reductase, or conjugation with glucuronic acid. Mercaptopurine impurity standard has been shown to be stable under acidic conditions and heat treatment at temperatures up to 200°C.Pureza:Min. 95%N2-Losartanyl-losartan
CAS:N2-Losartanyl-losartan is a drug product that has a CAS number of 230971-72-9. This product is an analytical standard for the metabolites of losartan, which is a drug used to treat high blood pressure and heart failure. Metabolism studies have shown that losartan is metabolized by hydroxylation, glucuronidation, and oxidation by cytochrome P450 enzymes. Losartan has also been found to be converted into an active metabolite in the body, which is called N2-hydroxy-losartan. It has been shown to be more potent than losartan at blocking angiotensin II receptors.Fórmula:C44H44Cl2N12OPureza:Min. 95%Peso molecular:827.81 g/mol[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl](4-hydroxyphenyl)-methanone
CAS:MDM2 inhibitors are a class of cancer drugs that inhibit the activity of MDM2, which is an oncoprotein that prevents the degradation of p53. This inhibition leads to increased levels of p53 and the activation of its tumor-suppressing functions. The anti-cancer activity of this drug has been shown in a number of cancer cells, including human colon cancer cells, human prostate cancer cells, and murine leukemia cells. Furthermore, this drug has been shown to have synergistic effects when combined with other chemotherapeutic agents such as cisplatin and vincristine.Fórmula:C21H14O4SPureza:Min. 95%Peso molecular:362.4 g/molα-Hydroxy-cyclohexanemethanesulfonic acid sodium salt
CAS:Please enquire for more information about α-Hydroxy-cyclohexanemethanesulfonic acid sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C7H14NaO4SPureza:Min. 95%Peso molecular:217.24 g/molNbi 27914 hydrochloride
CAS:NBI 27914 hydrochloride is a small molecule that binds to and blocks the neurotransmitter receptor for norepinephrine, which is involved in the regulation of mood. This drug has been shown to have anxiolytic-like effects in animals and may be useful for treating anxiety disorders that are due to congenital adrenergic hyperactivity. NBI 27914 hydrochloride also has an anxiogenic effect at high doses, which may be due to its ability to bind and block beta-adrenergic receptors. It is also able to act as a specific agonist or antagonist of alpha-adrenergic receptors.Fórmula:C18H21Cl5N4Pureza:Min. 95%Peso molecular:470.6 g/molIferanserin
CAS:Iferanserin is a medicinal analog that has shown promising anticancer activity. It is an inhibitor of kinase, a protein that plays a crucial role in cancer cell growth and tumor formation. Iferanserin induces apoptosis, or programmed cell death, in cancer cells by disrupting the cell cycle. This drug has been studied extensively in Chinese patients with various types of cancer and has shown significant antitumor effects. Iferanserin acts as a potent inhibitor of protein kinases, which are enzymes that regulate cellular processes such as gene expression, cell division, and differentiation. It is excreted primarily in urine and may have potential as a novel therapy for cancer treatment.Fórmula:C23H28N2OPureza:Min. 95%Peso molecular:348.5 g/molMMPI-1154
CAS:MMPI-1154 is an analog of a protein kinase inhibitor that has shown promising anticancer activity. It has been found to be effective against various types of cancer cells, including leukemia cells. MMPI-1154 works by inducing apoptosis, or programmed cell death, in cancer cells. It inhibits the activity of certain kinases that are involved in the growth and survival of cancer cells. This inhibitor has been isolated from urine samples of Chinese medicinal plants and shows potential as a tumor growth inhibitor in humans. MMPI-1154 is a promising new class of anticancer drugs that may offer hope for those suffering from cancer.Fórmula:C26H24FN3O3Pureza:Min. 95%Peso molecular:445.5 g/molMSC2360844
CAS:MSC2360844 is a Chinese medicinal analog that has shown potent anticancer activity against various types of tumors. It functions as an inhibitor of kinases, which are proteins involved in cell signaling and growth regulation. MSC2360844 induces apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of specific kinases. This inhibitor has been shown to be effective against multiple cancer cell lines and has potential therapeutic applications for the treatment of cancer. MSC2360844 is excreted through urine after administration and shows promising results in preclinical studies as a potential anticancer agent.Fórmula:C26H27FN4O5SPureza:Min. 95%Peso molecular:526.6 g/molMethyl 6-(1-hydroxyethyl)-3-methyl-4-phenylpicolinate
CAS:Methyl 6-(1-hydroxyethyl)-3-methyl-4-phenylpicolinate is a synthetic chemical that is used as an analytical standard in chemical and pharmaceutical research. It has been shown to have a wide range of pharmacological effects, including antihypertensive, antidiabetic, and antiulcerogenic activities. Research into the drug product is ongoing.Fórmula:C16H17NO3Pureza:Min. 95%Peso molecular:271.31 g/molRuxolitinib Impurity 3
CAS:Ruxolitinib Impurity 3 is an analytical chemical that is used as a reference standard in the field of drug development. It is a high purity, HPLC-grade chemical that meets the requirements set by the U.S. Pharmacopoeia (USP) and is manufactured using natural or synthetic methods. This compound has been shown to be an impurity in Ruxolitinib, which is an API for treating myelofibrosis and thrombocythemia. Ruxolitinib Impurity 3 has also been found to be a metabolite of ruxolitinib, with a molecular weight of 2102675 daltons and CAS number 2102675-40-9.Fórmula:C17H19N5O2Pureza:Min. 95%Peso molecular:325.36 g/molNRX-252262
CAS:NRX-252262 is an inhibitor that has shown potent anticancer activity in various types of cancer cells. It is a Chinese hamster ovary cell-derived analog of indirubin, which is a natural compound found in human urine and glycerol. NRX-252262 inhibits kinases, which are enzymes that play a role in cell division and proliferation. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. NRX-252262 has been shown to be effective against multiple types of cancer, making it a promising candidate for cancer treatment. Its potent anticancer activity makes it one of the most sought-after inhibitors for cancer research and development of new treatments.Fórmula:C23H17Cl2F3N2O4SPureza:Min. 95%Peso molecular:545.4 g/mol6-Iodo-2-propoxy-3-propylquinazolin-4(3H)-one
CAS:6-Iodo-2-propoxy-3-propylquinazolin-4(3H)-one is a potent anticancer agent that inhibits the activity of specific kinases involved in cancer cell growth and proliferation. It has been shown to induce apoptosis, or programmed cell death, in cancer cells by blocking the activity of certain proteins. This compound is structurally similar to other kinase inhibitors used in medicinal chemistry, such as gefitinib and erlotinib. 6-Iodo-2-propoxy-3-propylquinazolin-4(3H)-one has been tested on human and Chinese hamster ovarian cells and has demonstrated significant antitumor activity. It is a promising candidate for the development of new cancer therapies due to its potent inhibitory effects on kinases involved in tumor growth and progression. Additionally, this chemical analog can be detected in urine samples, making it a useful tool for studying kinase activities in vivo.
Fórmula:C14H17IN2O2Pureza:Min. 95%Peso molecular:372.2 g/molPaclitaxel impurity 2
CAS:Paclitaxel impurity 2 is an analytical standard for the measurement of paclitaxel purity. Paclitaxel impurity 2 is a natural metabolite of paclitaxel, and its presence in a drug product is indicative of a higher level of contamination with paclitaxel. The impurity is found in concentrations greater than 10% up to 100%.Fórmula:C33H45NO8Pureza:Min. 95%Peso molecular:583.71 g/molN-(Cyclohexylcarbamoyl)-4-(2-((cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide
CAS:N-(Cyclohexylcarbamoyl)-4-(2-((cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide is a drug product that is an analytical standard. It is metabolized in the body to 4-aminobenzenesulfonamide and cyclohexylurea. This product has been shown to have antibacterial activity against Mycobacterium tuberculosis, Mycobacterium avium, and other bacteria. It also has analgesic properties, which may be due to its ability to inhibit prostaglandin synthesis.Fórmula:C22H34N4O4SPureza:Min. 95%Peso molecular:450.6 g/molCis-1,2-dihydroperillic acid
CAS:Cis-1,2-dihydroperillic acid is an endogenous metabolite of perillyl alcohol. It is formed in the liver from perillyl alcohol and is excreted in the urine. Cis-1,2-dihydroperillic acid has been shown to inhibit cell growth and induce cancer in animals and humans. Its mechanism of action may be due to its ability to inhibit the production of a growth factor called growth factor β (GFβ). This hormone stimulates the proliferation of mammary carcinomas and may also be involved in carcinogenesis. Cis-1,2-dihydroperillic acid is present in plasma at low concentrations, which have been measured using a human bioassay.
Fórmula:C10H16O2Pureza:Min. 95%Peso molecular:168.23 g/molTolycaine hydrochloride
CAS:Procaine is a local anesthetic that is used to block nerve conduction in the peripheral nervous system. Procaine is soluble in water, alcohol, and propylene glycol but insoluble in ether and chloroform. It is active at low concentrations and has long-lasting effects. In addition, procaine can be given by intramuscular injection or intravenously. It has been shown to be effective for the treatment of thromboses and as a preventive measure for people with heart disease who are prone to blood clots. Procaine also inhibits noradrenaline release from sympathetic nerve terminals and blocks the uptake of noradrenaline into sympathetic neurons at synapses.Fórmula:C15H23ClN2O3Pureza:Min. 95%Peso molecular:314.81 g/mol(3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt
CAS:(3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt is an impurity standard for the drug product. It is a synthetic metabolite that binds to proteins and has been found in human urine. The chemical synthesis of (3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6 heptenoic acid sodium salt was performed using a high purity custom synthesis and high purity pharmacopoeia grade reagents.Fórmula:C23H23FNNaO4Pureza:Min. 95%Peso molecular:419.42 g/molAtropine impurity G
Atropine impurity G is a natural metabolite that is found in the body as an impurity of atropine. It is a synthetic drug product that is used as an analytical standard for the quantification of atropine and other drugs. Atropine impurity G has been shown to inhibit metabolism studies, which may be due to its ability to inhibit CYP3A4 activity. This impurity can be detected using HPLC with UV detection.Pureza:Min. 95%Rabeprazole Impurity 2
CAS:Rabeprazole Impurity 2 is a research and development impurity standard that is used for qualitative analysis. It can be custom synthesized to meet specific needs, and it can also be used in drug product synthesis. Rabeprazole Impurity 2 is a high purity synthetic compound that has been pharmacopoeia-qualified. It can also be used as a metabolite or analytical standard, and it has been studied for its metabolism studies with HPLC-MS. Rabeprazole Impurity 2 has CAS No. 1807988-36-8.
Fórmula:C18H19N3O4Pureza:Min. 95%Peso molecular:341.36 g/mol(5Alpha)-Androst-9(11)-ene-3,17-dione
CAS:5α-Androst-9(11)-ene-3,17-dione is a drug product that has been custom synthesized for research and development purposes. This compound is a natural metabolite of testosterone. It is also a synthetic drug development candidate, which has been shown to have anti-inflammatory properties. 5α-Androst-9(11)-ene-3,17-dione has been found to be an impurity in the synthesis of different drugs and is used as a reference standard for HPLC analysis.
Fórmula:C19H26O2Pureza:Min. 95%Peso molecular:286.40 g/mol3,3',5,5'-Tetrachlorobiphenyl
CAS:Produto Controlado3,3',5,5'-Tetrachlorobiphenyl is a chemical compound that has been found in human urine and is potentially carcinogenic. Studies have shown that this compound can disrupt the menstrual cycle and may play a role in the development of cancer. However, recent research also suggests that 3,3',5,5'-Tetrachlorobiphenyl may have anticancer properties. In Chinese medicinal practices, it has been used as an inhibitor of protein kinases involved in tumor growth and proliferation. This compound has also been shown to induce apoptosis (programmed cell death) in cancer cells. Further research is needed to fully understand the potential benefits and risks associated with 3,3',5,5'-Tetrachlorobiphenyl.Fórmula:C12H6Cl4Pureza:Min. 95%Peso molecular:292 g/molBalsalazide 3-isomer
CAS:Balsalazide 3-isomer (BZ3) is a diacid that is used as an anti-hypertensive drug. BZ3 has been shown to be a prodrug of balsalazide, which is converted in vivo to the active form by hydrolysis of the ester linkage. The prodrug approach was designed to provide an orally available agent for use in patients with colitis and ulcerative colitis. The synthetic process begins with the reaction of salicylic acid and bisoprolol to form the ester product, which then undergoes a second reaction with acetyl chloride to form the acyl chloride intermediate. This intermediate reacts with balsalazide and yields BZ3 when heated to high temperatures. BZ3 contains no impurities because it is synthesized from pure starting materials, whereas commercially available balsalazide may contain impurities such as salicylic acid or colitis.Fórmula:C17H15N3O6Pureza:Min. 95%Peso molecular:357.32 g/mol6,7,8,9-Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (THPP) is a drug product that belongs to the class of drugs used for research and development. It has been shown to have antiinflammatory properties in animal models. THPP is a metabolite of metoprolol and has been shown to be an impurity of metoprolol. The analytical properties of THPP are not yet known. Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3--yl)-1--piperidinyl]ethyl]-2--methyl--4H--pyrido[1,2--a]pyrimidin--4oneFórmula:C23H28N4O3Pureza:Min. 95%Peso molecular:408.49 g/mol
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