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APIs para pesquisa e impurezas

APIs para pesquisa e impurezas

Os Ingredientes Farmacêuticos Ativos (APIs) são as substâncias nos medicamentos responsáveis por seus efeitos terapêuticos. Nesta seção, você encontrará uma ampla variedade de APIs destinados a uso em pesquisa. Esses compostos são essenciais para o desenvolvimento, teste e validação de novas formulações farmacêuticas. Na CymitQuimica, oferecemos APIs de alta qualidade para apoiar a pesquisa em descoberta e desenvolvimento de medicamentos.

Subcategorias de "APIs para pesquisa e impurezas"

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Foram encontrados 66875 produtos de "APIs para pesquisa e impurezas"

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  • Udp-3-O[R-3-hydroxymyristoyl]-N-acetylglucosamine

    CAS:

    UDP-3-O[R-3-hydroxymyristoyl]-N-acetylglucosamine is a potent inhibitor of tumor growth and has been used in medicinal research for its potential anticancer properties. It works by targeting kinases that are involved in the regulation of cell growth and survival, inducing apoptosis (programmed cell death) in cancer cells. UDP-3-O[R-3-hydroxymyristoyl]-N-acetylglucosamine is an analog of UDP-N-acetylglucosamine, which is a protein precursor found in human urine. This inhibitor has been shown to be effective against various types of cancer, including breast, lung, and prostate cancer. Additionally, it has been found to inhibit the activity of Chinese hamster ovary cells that produce proteins for therapeutic use. Overall, UDP-3-O[R-3-hydroxymyristoyl]-N-acetylglucosamine holds great promise as a potential anticancer

    Fórmula:C31H53N3O19P2
    Pureza:Min. 95%
    Peso molecular:833.7 g/mol

    Ref: 3D-IEA63629

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  • (1,2-Dimethylpropyl)benzene

    CAS:
    1,2-Dimethylpropylbenzene is an alkenylbenzene that is used as a precursor to other chemicals. It can be synthesized by the dehydrogenation of 1,2-dimethylethylbenzene with a nickel catalyst or by the formylation of benzene with formaldehyde and potassium hydroxide. The cyclohexenyl group in 1,2-dimethylpropylbenzene can be converted to an alkene group by alkylation with acetylene. The linear regression analysis showed that the toolkit of 1,2-dimethylpropylbenzene isomerization reactions are useful for the synthesis of many different compounds and provide a better understanding of their reactivity.
    Fórmula:C11H16
    Pureza:Min. 95%
    Cor e Forma:Clear Liquid
    Peso molecular:148.24 g/mol

    Ref: 3D-ID157102

    2mg
    136,00€
    5mg
    142,00€
    10mg
    195,00€
    25mg
    292,00€
  • D-[Pro]31-Tirzepatide


    Tirzepatide impurity.

    Fórmula:C225H348N48O68
    Peso molecular:4,813.5 g/mol

    Ref: 3D-IP11028

    1mg
    518,00€
    10mg
    2.574,00€
    100mg
    7.721,00€
  • 2-Phenylbutyric acid

    CAS:

    2-Phenylbutyric acid is a product of the oxidation of phenylacetic acid by flavus. 2-Phenylbutyric acid is an inhibitor of contactor reactions that use α1-acid glycoprotein as a chromatographic support. It has been shown to inhibit the reaction mechanism of extractants (e.g., butamirate citrate) with enantiomeric compounds (e.g., creatine). It also inhibits subclinical mastitis in cows and fatty acid synthesis, leading to decreased cholesterol synthesis in humans.

    Fórmula:C10H12O2
    Pureza:Min. 95%
    Peso molecular:164.2 g/mol

    Ref: 3D-FP26945

    250g
    366,00€
    500g
    489,00€
    1kg
    771,00€
    2kg
    1.163,00€
    5kg
    2.124,00€
  • Olmesartan

    CAS:

    Olmesartan medoxomil is a prodrug that is hydrolyzed to olmesartan, its active form. It is a member of the angiotensin II receptor antagonists and it is used for the treatment of hypertension and heart failure. Olmesartan medoxomil reduces the risk of cardiovascular events in patients with resistant hypertension or heart failure. The drug binds to the angiotensin II type 1 receptor, thereby blocking the binding of angiotensin II to this receptor. This prevents activation of downstream signaling pathways, including phospholipase C, protein kinase C, and mitogen-activated protein kinases. Olmesartan medoxomil also blocks the formation of new blood vessels and vascular remodeling in animal models.

    Fórmula:C24H26N6O3
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:446.5 g/mol

    Ref: 3D-IH57928

    100mg
    203,00€
    250mg
    444,00€
    500mg
    733,00€
    1g
    1.308,00€
    2g
    2.106,00€
  • Aztreonam impurity D

    CAS:
    Aztreonam impurity D is a metabolite of aztreonam. Aztreonam impurity D is an impurity standard for the pharmacopoeia and API industry, as well as for drug development and research. It has been shown that this compound inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Aztreonam impurity D also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
    Fórmula:C13H17N5O5S
    Pureza:Min. 95 Area-%
    Cor e Forma:Powder
    Peso molecular:355.37 g/mol

    Ref: 3D-IA167738

    1mg
    188,00€
    2mg
    274,00€
    5mg
    491,00€
    10mg
    673,00€
    25mg
    1.142,00€
  • (S)-2-Ethylbutyl 2-aminopropanoate hydrochloride

    CAS:
    Remdesivir impurity
    Fórmula:C9H20ClNO2
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:209.71 g/mol

    Ref: 3D-FE175846

    2g
    215,00€
    5g
    403,00€
    10g
    627,00€
    25g
    1.060,00€
    50g
    1.599,00€
  • Aceclofenac methyl ester

    CAS:
    Aceclofenac methyl ester is an analgesic that belongs to the arylpropionic acid derivatives. It has been developed for the treatment of acute pain. Aceclofenac methyl ester has a structural formula of CH3CO-O-CH3 and a molecular weight of 164.2 g/mol. Aceclofenac is metabolized by CYP450 enzymes, which are located in the liver and other organs, to form acetic acid and 5-hydroxyaceclofenac. The reaction time is approximately 1 hour and tetrahydrofuranyl (THF) is used as a nucleophile in this reaction. This product can be synthesized by reacting ethyl acetate with acetonitrile in high yield, making it stable and anhydrous. The analgesic effects of aceclofenac methyl ester are due to its ability to block the transmission of pain signals from nerves to the brain at the spinal cord level
    Fórmula:C17H15Cl2NO4
    Pureza:Min. 98 Area-%
    Cor e Forma:White Powder
    Peso molecular:368.21 g/mol

    Ref: 3D-IA16911

    10mg
    201,00€
    25mg
    322,00€
    50mg
    454,00€
    100mg
    673,00€
    250mg
    1.142,00€
  • Albendazole sulfoxide

    CAS:

    Albendazole sulfoxide is a sulfoxide of albendazole. The molecular docking analysis of the two molecules showed that the sulfoxide group is located in the same position as the hydroxyl group on albendazole. It has been shown that this replacement of hydroxyl with a sulfoxide group increases the solubility and stability of albendazole, which may be due to hydrogen bonding interactions between these groups. Albendazole sulfoxide has been shown to be an effective treatment for infections caused by parasites such as helminths. However, it should not be used in combination with drugs that are metabolized by cytochrome P450 enzymes because it can inhibit their activity.

    Fórmula:C12H15N3O3S
    Pureza:Min. 97 Area-%
    Cor e Forma:White Powder
    Peso molecular:281.33 g/mol

    Ref: 3D-IA17259

    10g
    287,00€
    25g
    449,00€
    50g
    599,00€
    100g
    946,00€
  • 1-Phenyl-1-(2-pyridinyl)ethanol hydrochloride

    CAS:
    1-Phenyl-1-(2-pyridinyl)ethanol hydrochloride is a natural product that is used as a pharmacopoeia standard for analytical and HPLC applications. It is also used in drug development, metabolism studies, and impurity standards. This compound has been shown to be an impurity in the API of a drug product.
    Fórmula:C13H13NO·HCl
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:235.71 g/mol

    Ref: 3D-IP58168

    250mg
    336,00€
    500mg
    472,00€
    1g
    804,00€
    2g
    1.430,00€
    5g
    3.221,00€
  • Lercanidipine impurity A

    CAS:

    Lercandipine Impurity A is a metabolite of the drug lercandipine. It is synthesized in the body by oxidation at the benzylic position of the cinnamoyl moiety. This impurity may be present in lercandipine-containing drugs and products, as well as in other drugs and products containing lercandipine. Lercandipine Impurity A has been shown to inhibit the metabolism of lercandipine and may also have anti-inflammatory properties. It is used as an analytical standard for HPLC, pharmacopoeia, drug development, and metabolism studies. Lercandipine Impurity A is found in the following: -Impurities of Lercandipine -Custom synthesis -Lercandipine Drug Product -Synthetic -High purity -Pharmacopoeia -Drug development

    Fórmula:C19H22N2O6
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:374.39 g/mol

    Ref: 3D-IL179227

    1mg
    378,00€
    2mg
    538,00€
    5mg
    765,00€
    10mg
    1.202,00€
    25mg
    1.802,00€
  • 7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one

    CAS:
    7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one is a palladium catalyst that can be used in a Buchwald reaction. This reaction is an industrially scalable process that has been developed to produce high yields of valuable organic compounds from inexpensive starting materials. The catalytic cycle involves the formation of the palladium species Pd(0) followed by its oxidative addition to an alkyl halide. This addition leads to the formation of a palladium(II) species and subsequent reductive elimination of hydrogen halide. 7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one is used as a catalyst in this process because it selectively reacts with electron rich aromatic substrates to form substituted benzoquinones or phenols. The product distribution is determined by the reactivity of the substrate and the relative rates of competing reactions. Impurities are formed during synthesis due to
    Fórmula:C13H16BrNO2
    Pureza:Min. 95%
    Peso molecular:298.18 g/mol

    Ref: 3D-FB19204

    -Unit-gg
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    10g
    A consultar
  • 6-Chloro-4-(2-chlorophenyl)-2-quinazolinecarboxaldehyde

    CAS:
    6-Chloro-4-(2-chlorophenyl)-2-quinazolinecarboxaldehyde is a colorimetric reagent that can be used to detect Cl. It has been shown to react with Cl in the presence of an acidic solution and produce a red color. The reagent is stable in organic solvents, such as chloroform, but decomposes in water. 6-Chloro-4-(2-chlorophenyl)-2-quinazolinecarboxaldehyde is also used to detect chloride by titrimetric or polarographic methods.
    Fórmula:C15H8Cl2N2O
    Pureza:Min. 95%
    Cor e Forma:Off-White Powder
    Peso molecular:303.14 g/mol

    Ref: 3D-IC20071

    5mg
    136,00€
    10mg
    158,00€
    25mg
    282,00€
    50mg
    423,00€
  • Ceftazidime impurity G

    CAS:

    Ceftazidime impurity G is a heterocycle that has been found to be a potential flavonoid. It has antiviral and protease inhibitory properties, which may be due to its ability to bind to the serine protease. It also has anti-inflammatory properties, which may be due to its inhibition of tyrosine kinase activity. Ceftazidime impurity G can be used as a pharmaceutical preparation for cardiovascular diseases, cancer, hepatitis, and other diseases.

    Fórmula:C11H14N4O5S
    Pureza:90%Min
    Cor e Forma:Powder
    Peso molecular:314.32 g/mol

    Ref: 3D-IC63720

    500µg
    355,00€
    1mg
    430,00€
    2mg
    546,00€
    5mg
    776,00€
    10mg
    1.035,00€
  • Cetirizine Impurity B

    CAS:

    Cetirizine Impurity B is a custom synthesis impurity. It is a product of the metabolism of cetirizine, an anti-allergic drug. Cetirizine Impurity B is used as an impurity standard for drug development and analytical HPLC studies. It has been assigned CAS number 113740-61-7 by the Chemical Abstracts Service. The purity of this compound is greater than 99%.

    Fórmula:C19H21ClN2O2
    Pureza:Min. 90 Area-%
    Cor e Forma:Powder
    Peso molecular:344.8 g/mol

    Ref: 3D-IC181078

    250mg
    454,00€
    1g
    956,00€
    2g
    1.442,00€
    5g
    2.340,00€
  • Montelukast ketone impurity

    CAS:
    The impurity (2,6-dichlorobenzaldehyde) is a metabolite of montelukast. It is an analytical impurity that has been quantified in the drug product and has also been found to be present in the synthetic process. The impurity standard was developed using HPLC. It can be used as a high purity reference material for pharmacopoeia and custom synthesis.
    Fórmula:C29H26ClNO2
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:455.97 g/mol

    Ref: 3D-IM111859

    5mg
    292,00€
    10mg
    458,00€
    25mg
    733,00€
    50mg
    1.163,00€
    100mg
    1.890,00€
  • Bisoprolol impurity K

    CAS:

    Bisoprolol impurity K is a drug product that is an analytical standard used for the detection and identification of bisoprolol in pharmaceutical products. It is a synthetic impurity with CAS No. 864544-37-6 that does not have any pharmacological activity. Bisoprolol impurity K is a high purity HPLC standard that can be used to develop analytical methods for the determination of bisoprolol in pharmaceutical products.

    Fórmula:C18H29NO5
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:339.43 g/mol

    Ref: 3D-IK24763

    1mg
    136,00€
    2mg
    180,00€
    5mg
    322,00€
    10mg
    454,00€
  • Simvastatin hydroxy acid ethyl ester

    CAS:
    Simvastatin hydroxy acid ethyl ester is a solvated form of simvastatin, an investigational drug for the treatment of dyslipidemia. The ammonium salt was prepared by alcoholysis with ethanol. The elution process was carried out using an acetonitrile-water mixture and chromatography on silica gel. Preparation methods were investigated to determine the best preparative procedure that would yield pure material. This compound has been investigated as a possible therapeutic agent for the treatment of midbody diseases such as familial amyloidotic polyneuropathy and Alzheimer's disease.
    Fórmula:C27H44O6
    Pureza:Min. 95%
    Cor e Forma:Colourless To Pale Yellow Liquid
    Peso molecular:464.63 g/mol

    Ref: 3D-IS27836

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  • 3-[Benzyl(methyl)amino]-1-phenylpropan-1-one

    CAS:
    3-[Benzyl(methyl)amino]-1-phenylpropan-1-one is a glycol that has been optimized for synthesis. It is used in research to prepare nitrates, which are stoichiometric reagents. Dimethylformamide and dioxane are reagents that can be used for this purpose. The yields of 3-[Benzyl(methyl)amino]-1-phenylpropan-1-one depend on the irradiation time, so it is important to maximize this variable. Phase extraction can be used to purify the product after irradiation. 3-[Benzyl(methyl)amino]-1-phenylpropan-1-one may act as a receptor modulator by binding to G protein coupled receptors and activating them or inhibiting their activation. This drug has also been shown to inhibit the production of nitric oxide, which is an important mediator in inflammation and vascular diseases such as hypertension and atherosclerosis.
    Fórmula:C17H19NO
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:253.34 g/mol

    Ref: 3D-IB158700

    2g
    167,00€
    5g
    286,00€
    10g
    403,00€
    25g
    849,00€
  • Rifaximin EP Impurity D


    Rifaximin EP Impurity D is an analytical impurity that has been identified as a metabolite of the drug Rifaximin. It is a white crystalline powder with no characteristic odor. This product can be used as an HPLC standard, niche compound, or pharmacopoeia impurity. It can also be custom synthesized to meet the needs of your research and development project.

    Pureza:Min. 95%

    Ref: 3D-IR181351

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