APIs para pesquisa e impurezas
Subcategorias de "APIs para pesquisa e impurezas"
- Aminoácidos e Derivados(12.335 produtos)
- Antraquinonas e Derivados(405 produtos)
- Derivados de Benzimidazol e Imidazol(10.451 produtos)
- Derivados das Benzodiazepinas(334 produtos)
- Carboidratos e Glicoconjugados(5.048 produtos)
- Ésteres e Derivados(42.251 produtos)
- Ácidos Graxos e Derivados Lipídicos(32.418 produtos)
- Flavonoides e Polifenóis(17.084 produtos)
- Radicais Livres e Agentes Oxidantes/Redutores(213 produtos)
- Cetonas e Derivados(2.402 produtos)
- Antibióticos Naturais e Semissintéticos(6.388 produtos)
- Nitrilas e Derivados Ciano(3.068 produtos)
- Nitrosaminas e Derivados(55 produtos)
- Nucleosídeos e Nucleotídeos(3.484 produtos)
- Fosfatos e Fosfonatos Orgânicos(1.201 produtos)
- Sulfonatos e Sulfatos Orgânicos(10.435 produtos)
- Compostos Organometálicos(4.421 produtos)
- Outros(6.307 produtos)
- Peptídeos e Proteínas(3.148 produtos)
- Polímeros e Derivados(100 produtos)
- Derivados de Purinas e Pirimidinas(8.948 produtos)
- Derivados de Quinazolina e Quinolina(66.046 produtos)
- Quinonas e Derivados(24.364 produtos)
- Sais e Derivados de API(80.492 produtos)
- Esteroides e Derivados(4.958 produtos)
- Sulfonamidas e Derivados(2.600 produtos)
- Terpenoides e Derivados(3.850 produtos)
- Tiazolidinedionas e Tiopiranos(2.754 produtos)
- Compostos β-Adrenérgicos(231 produtos)
Foram encontrados 57774 produtos de "APIs para pesquisa e impurezas"
Exicorilant
CAS:Exicorilant is an analog of capsaicin, which has been shown to have anticancer properties. It is a potent inhibitor of protein kinases and has been demonstrated to induce apoptosis in human cancer cells. Exicorilant specifically targets tumor cells and inhibits their growth by blocking the activity of certain kinases that are essential for cell division. This anticancer drug has been tested on Chinese hamster ovary cells and found to be effective in inhibiting the growth of various types of cancer cells. In addition, exicorilant has shown promising results in urine samples from patients with advanced cancers, indicating its potential as a diagnostic tool for cancer detection. Overall, exicorilant is a promising inhibitor with potential therapeutic applications for cancer treatment.
Fórmula:C26H23F4N7O3SPureza:Min. 95%Peso molecular:589.6 g/molRef: 3D-GWC24477
Produto descontinuado2-[2-[4-(5,5-Dioxidodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy]ethanol
CAS:Quetiapine is a drug that belongs to the class of sulfoxides. It is usually administered orally, but can also be given intravenously or intramuscularly. Quetiapine has been studied for its clinical use in the treatment of schizophrenia and bipolar disorder. The plasma concentrations of quetiapine are determined by high-performance liquid chromatography (HPLC) with tandem mass spectrometry (LC-MS/MS) detection. Validation studies have shown that the HPLC-MS/MS method is accurate and precise, with good linearity over a range of concentrations. Analysis was performed on plasma samples from healthy volunteers who were administered either 2 mg or 10 mg doses of quetiapine by intravenous injection. Concentrations were calculated and compared to those found in patients with schizophrenia and bipolar disorder who had been given oral doses of 300 mg per day for four weeks, yielding a therapeutic plasma concentration range from 100 to 300 ng/mL.
Fórmula:C21H25N3O4SPureza:Min. 95%Peso molecular:415.51 g/molDL-threo-Ritalinic acid
CAS:Produto ControladoDL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.
Fórmula:C13H17NO2Pureza:Min. 95%Peso molecular:219.28 g/molGyromitrin
CAS:Gyromitrin is a potent inhibitor of tumor growth and apoptosis in human cancer cells. It is an analog of tylosin, a macrolide antibiotic used in veterinary medicine. Gyromitrin has been shown to inhibit the activity of kinases involved in cell proliferation and survival, leading to decreased cell growth and increased apoptosis. In Chinese hamster ovary cells, gyromitrin has been demonstrated to be a potent inhibitor of protein synthesis. This compound has also been found in urine samples from humans who have ingested mushrooms containing gyromitrin. Menthol has been found to be an effective inhibitor of gyromitrin-induced DNA damage and may have potential as a chemopreventive agent against cancer.
Fórmula:C4H8N2OPureza:Min. 95%Peso molecular:100.12 g/molRef: 3D-RAA56802
Produto descontinuadoDioctyl carbonate
CAS:Dioctyl carbonate is a pharmaceutical preparation used to treat skin conditions. It is a fatty acid ester of carbonic and carbonyl groups in which the two esters are in the same molecule. Dioctyl carbonate is a reaction product obtained by reacting an inorganic acid, such as hydrochloric acid or sulfuric acid, with an alcohol containing two hydroxyl groups and one double bond. This reaction may be facilitated by heating. The film-forming polymer may be polyvinylpyrrolidone, polyvinyl alcohol, or polyacrylic acid. Dioctyl carbonate has been shown to stimulate colony-stimulating factor production and inhibit the proliferation of human epidermal keratinocytes.
Fórmula:C17H34O3Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:286.4 g/mol4-(4-Aminophenyl)phthalazin-1(2H)-one
CAS:4-(4-Aminophenyl)phthalazin-1(2H)-one is an antibacterial drug that belongs to the class of amide and minimise. It has a constant, synthetic, and chalcone profile. 4-(4-Aminophenyl)phthalazin-1(2H)-one has been shown to have antiplatelet activity in animals. This drug also inhibits the production of proinflammatory cytokines such as IL-6, IL-8, and TNFα by human monocytes. This drug also has antidiabetic properties and a safety profile similar to other nonsteroidal anti-inflammatory drugs.
Fórmula:C14H11N3OPureza:Min. 95%Peso molecular:237.26 g/molRef: 3D-GFA74153
Produto descontinuadoVarenicline N-oxide
CAS:Varenicline N-oxide is a synthetic drug product. It is the metabolite of varenicline, which is used as an aid to smoking cessation. Varenicline N-oxide has shown anti-inflammatory properties in vitro and in vivo, and may be useful for treating inflammatory diseases. Varenicline N-oxide also has been shown to inhibit the production of nitric oxide in macrophages and prevent the release of tumor necrosis factor alpha by macrophages.
Fórmula:C13H13N3OPureza:Min. 95%Peso molecular:227.26 g/molRef: 3D-IV177544
Produto descontinuado(trans)-4-Propyl-1-methyl-L-proline
CAS:(trans)-4-Propyl-1-methyl-L-proline is a synthetic compound that has been used in the past as an impurity standard in the synthesis of several drugs, including metaxalone and aminopyrine. It is also found to have pharmacological effects on its own and was used as a drug product for the treatment of rheumatoid arthritis. (trans)-4-Propyl-1-methyl-L-proline is not listed in any pharmacopoeia or international list of approved drugs.
Fórmula:C9H17NO2Pureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:171.24 g/molRef: 3D-FP27224
Produto descontinuadoBortezomib impurity 76
CAS:Bortezomib impurity 76 is an analytical reference material that is used in the development and production of pharmaceuticals. It is a high purity, HPLC standard for use as an impurity in the manufacture of bortezomib API. This material is a metabolite of bortezomib and it has been shown to be pharmacologically active. Bortezomib impurity 76 can also be used as an HPLC standard for drug product analysis.
Fórmula:C21H44BNO2Si2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:409.56 g/molRef: 3D-IB181070
Produto descontinuadoOzagrel impurity III
CAS:Please enquire for more information about Ozagrel impurity III including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C13H16O2Pureza:Min. 95%Peso molecular:204.26 g/molRef: 3D-JIA33421
Produto descontinuado1-Benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate
CAS:Please enquire for more information about 1-Benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C20H27NO4SPureza:Min. 95%Peso molecular:377.5 g/molRef: 3D-TUA04020
Produto descontinuadoMinocycline EP Impurity H
CAS:Please enquire for more information about Minocycline EP Impurity H including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C23H25N3O7Pureza:Min. 95%Peso molecular:455.47 g/molRef: 3D-IM183785
Produto descontinuadoN-Acetyl N-descarboxyethyl retigabine d4
CAS:N-Acetyl N-descarboxyethyl retigabine (D4) is a pharmaceutical drug that is used for the treatment of epilepsy. It has been shown to be effective in patients who have not responded to other treatments. D4 binds to voltage-gated potassium channels and inhibits their opening, which leads to a decrease in neurotransmitter release from nerve cells. The mechanism by which D4 induces epileptic seizures is unclear but may be due to its ability to inhibit the activity of GABA receptors in the brain.Fórmula:C15H16FN3OPureza:Min. 95%Peso molecular:273.3 g/molRef: 3D-EJA97068
Produto descontinuado(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS:(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.
Fórmula:C15H15NPureza:Min. 95%Cor e Forma:PowderPeso molecular:209.29 g/molDesmethyl dabrafenib
CAS:Desmethyl dabrafenib is a synthetic drug product that is used in research and development. It is an impurity standard for dabrafenib, a prodrug of dabrafenib which has been shown to inhibit the growth of cancer cells by inhibiting the synthesis of proteins. Desmethyl dabrafenib is metabolized through CYP3A4/5-mediated oxidation and glucuronidation. It also undergoes phase I metabolism through CYP1A2 and 2C19, leading to formation of a major metabolite with no activity. This compound has been shown to have natural sources in plants such as rhubarb and soybeans.
Fórmula:C22H18F3N5O2S2Pureza:Min. 95%Peso molecular:505.50 g/molRef: 3D-VXB76547
Produto descontinuadoLumiflavin 5-oxide
CAS:Lumiflavin 5-oxide is a metabolite of lumiflavin. It is a synthetic compound that is used as an analytical reference standard for impurities in lumiflavin and other pharmaceuticals. Lumiflavin 5-oxide has been shown to be metabolized through the cytochrome P450 system, with oxidative metabolites being formed by CYP1A2 and CYP3A4. Lumiflavin 5-oxide has also been shown to be a competitive inhibitor of NAD+-dependent enzymes such as glycerol kinase, phosphofructokinase, lactate dehydrogenase, alcohol dehydrogenase, and glucose 6-phosphate dehydrogenase.
Fórmula:C13H12N4O3Pureza:Min. 95%Peso molecular:272.26 g/molAceclofenac benzyl ester
CAS:Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the propionic acid derivative group. It is used in the treatment of mild to moderate pain and inflammation, such as arthritis. Aceclofenac is rapidly hydrolyzed by esterases in the small intestine, resulting in the release of aceclofenac acid. Aceclofenac benzyl ester is a chemical intermediate that has been shown to be an efficient method for producing aceclofenac acid. It can be obtained by reacting bromoacetic anhydride with methyl alcohol and then hydrolyzing the product with strong acids. This compound may contain impurities, such as nucleophilic impurities, which can lead to side effects.
Fórmula:C23H19Cl2NO4Pureza:Min. 95%Peso molecular:444.31 g/molRef: 3D-IA16909
Produto descontinuado42-o-tert-Butyldimethylsilyloxyethyl rapamycin
CAS:Rapamycin is a natural product from Streptomyces hygroscopicus. It has been shown to inhibit T- and B-lymphocyte proliferation, induce apoptosis of lymphocytes, and suppress both humoral and cell-mediated immune responses. Rapamycin is also an immunosuppressant that decreases the incidence of rejection in organ transplant patients. Rapamycin is used as a drug product in the form of a sterile solution for injection. The purity of rapamycin should be at least 99%, with less than 1% impurities, such as 42-O-tert-butyldimethylsilyloxyethyl rapamycin (TBDMS). Rapamycin is not currently available on the market as an API, but it may be custom synthesized for research purposes or for clinical trials.Fórmula:C59H97NO14SiPureza:Min. 95%Peso molecular:1,072.49 g/molMesulergine hydrochloride
CAS:Mesulergine hydrochloride is a drug that inhibits the dopamine and serotonin receptors. It has been shown to have an effect on rats' serum prolactin levels, food composition, and protein transport in the striatum. Mesulergine hydrochloride can also decrease 5-HT7 receptor binding and increase dopamine release from nerve terminals in the rat brain. This drug has synergistic effects with other drugs when used in combination, such as gamma-aminobutyric acid (GABA) or benzodiazepines.
Symptoms of mesulergine hydrochloride include psychotic disorders, anxiety, depression, hallucinations, sleep problems, and suicidal thoughts. These symptoms may be due to mesulergine's effect on 5-HT2C receptors.Fórmula:C18H27ClN4O2SPureza:Min. 95%Peso molecular:399 g/molRef: 3D-XCA78612
Produto descontinuadoRisperidone E-oxime impurity
CAS:Risperidone E-oxime impurity is a drug product that has been studied for its metabolism in humans, animals and plants. It is an analytical standard that is used as an impurity in the synthesis of risperidone. Risperidone E-oxime impurity is also a synthetic compound with CAS No. 691007-09-7. It can be used as a pharmacopoeia high purity HPLC standard and as a research and development synthetic compound.
Fórmula:C23H28F2N4O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:430.49 g/molRef: 3D-IR27738
Produto descontinuadoIrinotecan lactone impurity
CAS:Irinotecan is a drug product that is used in the treatment of cancer. It is a prodrug that must be activated by metabolism to its active form, SN-38. Irinotecan lactone impurity is an impurity standard and has been shown to have analgesic properties in mice. It has also been shown to inhibit the growth of colon cancer cells.
Fórmula:C32H36N4O5Pureza:Min. 95%Peso molecular:556.7 g/molRef: 3D-II180814
Produto descontinuadoL-Valine 2-hydroxyethyl ester tosylate
CAS:L-Valine 2-hydroxyethyl ester tosylate (L-V2HT) is a drug product that is synthesized by custom synthesis. It has high purity, analytical, and natural properties. L-V2HT is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The active form of L-V2HT is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. L-V2HT also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell
Fórmula:C14H23NO6SPureza:Min. 95%Peso molecular:333.4 g/molRef: 3D-IV178763
Produto descontinuadoDuloxetine phenyl carbamate
CAS:Duloxetine is a drug product that belongs to the class of drugs known as selective serotonin and norepinephrine reuptake inhibitors. Duloxetine is a metabolite of duloxetine phenyl carbamate, which is an impurity standard for HPLC analysis. Duloxetine has been shown to inhibit the metabolism of serotonin and norepinephrine in the brain, leading to increased amounts of these neurotransmitters. This medication has been studied in niche populations such as those with depression and diabetic neuropathy. Duloxetine also has high purity standards, meeting the requirements of pharmacopoeia.
Fórmula:C25H23NO3SPureza:Min. 95%Peso molecular:417.50 g/molRef: 3D-XMB68609
Produto descontinuadoCarbidopa 4-phosphate trihydrate
CAS:Please enquire for more information about Carbidopa 4-phosphate trihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C10H21N2O10PPureza:Min. 95%Peso molecular:360.25 g/molRef: 3D-HBD68607
Produto descontinuadoPreterramide C
CAS:Preterramide C is a drug that belongs to the class of drugs known as aminopyridines. It is a metabolite of preterramide A and has been used as an analytical reference standard for HPLC. This product is available in the form of a pure white crystalline powder with a purity greater than 98%. It has been shown to be an impurity in drug products and can be used as an impurity standard, as well as being synthesized by natural or synthetic means.
Fórmula:C24H23N3O7Pureza:Min. 95%Peso molecular:465.50 g/molRef: 3D-GDA46977
Produto descontinuadorac 5-Keto Fluvastatin
CAS:Rac5-Keto Fluvastatin is a synthetic, natural and custom synthesis drug product. It's CAS number is 1160169-39-0. Rac5-Keto Fluvastatin is a metabolite of fluvastatin. The racemic mixture has been prepared by the organic synthesis of racemic 5-keto fluvastatin, which was achieved by the use of a chiral auxiliary. Rac5-Keto Fluvastatin can be used in metabolism studies, as an analytical standard for HPLC, and as a reference material for pharmacopoeia.
Fórmula:C24H24FNO4Pureza:Min. 95%Cor e Forma:Yellow PowderPeso molecular:409.45 g/molN-Desmethyl trimeprazine
CAS:N-Desmethyl trimeprazine is a synthetic compound, which is an impurity of the drug product. It is not active and does not possess any biological activity. It is a metabolite of the parent drug, Trimeprazine. N-Desmethyl trimeprazine has been studied for its pharmacological properties and metabolism in the body, but no conclusive results have been found. The chemical structure and purity of N-Desmethyl trimeprazine are not listed in the USP or BP. This compound can be custom synthesized on request.
Fórmula:C17H20N2SPureza:Min. 95%Peso molecular:284.40 g/molRef: 3D-XAA73204
Produto descontinuado3-(2-Fluorophenyl) ezetimibe
CAS:3-(2-Fluorophenyl) ezetimibe is an impurity of the drug product Ezetimibe. It is a metabolite that has been shown to have analytical and research and development applications. 3-(2-Fluorophenyl) ezetimibe is soluble in organic solvents such as acetone, ethanol, or chloroform and insoluble in water. The impurity standard for 3-(2-Fluorophenyl) ezetimibe conforms to the USP/NF monograph for Ezetimibe Impurities A, B, C, D, E and F. The CAS number for this impurity is 1798008-25-9.
Fórmula:C24H21F2NO3Pureza:Min. 95%Peso molecular:409.40 g/molRef: 3D-YWC00825
Produto descontinuado2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS:2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].
Fórmula:C15H15N3OS2Pureza:Min. 95%Peso molecular:317.43 g/mol2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
CAS:2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole (CAS No. 168167-42-8) is a synthetic compound that is used as an analytical reference standard for HPLC. It is also used in the study of drug metabolism, and it has been shown to induce natural oxidation in vitro. 2-[(4-Chloro-3-methylpyridinium)methylsulfinyl]-1Hbenzimidazole is an impurity found in pharmaceutical products that are synthesized from 1-(2,4,6trichlorophenyl)-3-[(4chloromethyl)phenyl]urea.Fórmula:C14H12ClN3OSPureza:Min. 95 Area-%Cor e Forma:Brown PowderPeso molecular:305.78 g/molRef: 3D-IC21226
Produto descontinuado(2S,2R,Trans)-saxagliptin
CAS:(2S,2R,Trans)-saxagliptin is an anti-diabetic drug that belongs to the thiazolidinedione class of drugs. It is a synthetic compound that is metabolized by cytochrome P450 enzymes and excreted in urine. (2S,2R,Trans)-saxagliptin has been shown to inhibit the synthesis of glucose in liver cells and to lower blood glucose levels in diabetic animals. In addition, it has been shown to have anti-inflammatory effects by inhibiting the production of TNF-α and IL-6 cytokines.
Fórmula:C18H25N3O2Pureza:Min. 95%Peso molecular:315.40 g/molMoexipril-d5
CAS:Please enquire for more information about Moexipril-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C27H34N2O7Pureza:Min. 95%Peso molecular:503.6 g/molRef: 3D-GEC92949
Produto descontinuado5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane
CAS:5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane is an analytical standard used in HPLC and GC. It can also be used as a research and development standard or impurity to aid in the identification of compounds with similar structures. 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane has a purity of 99% and a melting point of 80°C. The CAS number for this compound is 93413-70-8, and it is available for custom synthesis, natural, or synthetic production.
Fórmula:C17H25NO2Pureza:Min. 95%Peso molecular:275.39 g/molRef: 3D-IM28679
Produto descontinuadoRisperidone carboxylate impurity
CAS:Risperidone carboxylate impurity is an analytical reference standard of risperidone that is used in the research and development, drug development, and production of drugs. It can be used as an impurity standard for the manufacture of pharmaceuticals. Risperidone carboxylate impurity has a molecular weight of 514.83 g/mol and a melting point of 200-202°C. Its CAS number is 1346603-86-8. Metabolites are also known to form from risperidone carboxylate impurity during metabolism.
Fórmula:C24H27FN4O4Pureza:Min. 95%Peso molecular:454.50 g/molRef: 3D-WDC60386
Produto descontinuado11-Oxo-betamethasone-17-carboxylic acid
CAS:Produto ControladoPlease enquire for more information about 11-Oxo-betamethasone-17-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C21H25FO5Pureza:Min. 95%Peso molecular:376.4 g/molRef: 3D-EDA57810
Produto descontinuadoN-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide
CAS:N-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide is a synthetic compound that has not been identified in nature. It is used for analytical purposes and as an impurity standard in the synthesis of other compounds. N-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide is the parent drug product of CAS No. 896736–22–4. The impurities found in this product are N-[2-(3′-(3″S″)-3′′S″′) (3″R″) -1H -indenyl](methyl)amine hydrochloride and N-[
Fórmula:C16H19NO3Pureza:Min. 95%Peso molecular:273.33 g/molRef: 3D-WKB73622
Produto descontinuado2-Methoxy-5-sulfamoylbenzoic acid
CAS:2-Methoxy-5-sulfamoylbenzoic acid (2MSBA) is a reactive compound that reacts with the proton of vancomycin to form a dianion. This reaction is reversible and can be catalyzed by chloride ions. 2MSBA has been shown to be active against Staphylococcus, including MRSA strains, but not against Enterococci or Clostridium difficile. 2MSBA can be used in combination with cefepime or benzoate as an antibacterial agent. It also has antifungal properties, which may be due to its ability to inhibit the synthesis of ergosterol, an important component of fungal cell membranes.
2-Methoxy-5-sulfamoylbenzoic acid is related to fluconazole in that it contains a benzoate moiety and an amide group. These structural features confer antibacterial and antifFórmula:C8H9NO5SPureza:Min. 95%Peso molecular:231.23 g/molRef: 3D-IM145487
Produto descontinuadoAcrolein-d4
CAS:Please enquire for more information about Acrolein-d4 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C3H4OPureza:Min. 95%Peso molecular:60.09 g/molRef: 3D-IBA98405
Produto descontinuadorac-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine
CAS:Rac-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine is an organic compound with the molecular formula C10H14N. Racemic rac-1,2,3,4-tetrahydro-5-methoxy-N propyl 2 naphthalenamine has been used in the synthesis of rotigotine. The enantiomers can be separated by means of an electrophoretic method. Racemic rac 1,2 3 4 tetrahydro 5 methoxy n propyl 2 naphthalenamine has a melting point range of 138 to 141 °C and a boiling point range of 285 to 288 °C at atmospheric pressure. This compound is soluble in organic solvents such as chloroform and ethanol and insoluble in water. It has a density of 1.07 g/cm3 at 20 °C and it isFórmula:C14H21NOPureza:Min. 95%Peso molecular:219.32 g/molRef: 3D-DAA89907
Produto descontinuadoDoxylamine N-oxide
CAS:Doxylamine N-oxide is a drug product that is custom synthesized to meet the specific needs of the customer. It has a purity of > 98% and is synthesized with natural starting materials. Doxylamine N-oxide inhibits bacterial growth through inhibition of protein synthesis, which may be due to its ability to inhibit methionine synthase. This drug also has been shown to be effective in the treatment of malaria, although it does not have significant anti-malarial properties. Doxylamine N-oxide has been used as a metabolite marker for other drugs and as an impurity standard for HPLC analysis.
Fórmula:C17H22N2O2Pureza:Min. 95%Peso molecular:286.37 g/molBoc-3-hydroxy-1-adamantyl-glycine
CAS:Boc-3-hydroxy-1-adamantyl-glycine is a catalytic, nucleophilic, chiral amino acid that is used in the synthesis of oximes. Boc-3-hydroxy-1-adamantyl-glycine has been shown to be an effective substitute for hydroxylamine in reductive amination reactions and can be used to synthesize some pharmaceuticals, including saxagliptin. This compound is stable under standard conditions and can be easily synthesized. It is also a powerful nucleophile that reacts with electrophiles such as chloroformates and sulfonyl chlorides.
Fórmula:C17H27NO5Pureza:Min. 95%Peso molecular:325.4 g/molRef: 3D-JDC32139
Produto descontinuadocis-Tadalafil
CAS:Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.
Fórmula:C22H19N3O4Pureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:389.4 g/molAcarbose Impurity E
CAS:Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.
Pureza:Min. 95%Ref: 3D-FA175652
Produto descontinuado3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride
CAS:3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.
Fórmula:C19H25ClN2O2Pureza:Min. 95%Peso molecular:348.9 g/molRef: 3D-WMD18565
Produto descontinuadoTofacitinib dihydro impurity
CAS:Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.
Fórmula:C16H22N6OPureza:Min. 95%Peso molecular:314.39 g/molTerbinafine dihydrochloride
CAS:Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.
Fórmula:C36H40N2Pureza:Min. 95%Peso molecular:500.7 g/molSimvastatin acid
CAS:Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin
Fórmula:C25H40O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:436.58 g/molDicyclopropylamine hydrochloride
CAS:Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D
Fórmula:C6H11N•HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:133.62 g/molRef: 3D-FD141573
Produto descontinuadoDesfluoro ezetimibe
CAS:Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Fórmula:C24H22FNO3Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:391.43 g/molEmpagliflozin S-furanose
CAS:Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.
Fórmula:C23H27ClO7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:450.91 g/molPiperacilloic acid
CAS:Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.
Fórmula:C23H29N5O8SPureza:(Elemental Analysis) Min. 90 Area-%Cor e Forma:PowderPeso molecular:535.57 g/mol(4-Chlorophenyl)diphenylmethanol
CAS:Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C19H15ClOPureza:Min. 95%Peso molecular:294.8 g/molRef: 3D-GAA92289
Produto descontinuadoIvermectin impurity I
CAS:Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.
Fórmula:C48H74O14Pureza:Min. 95%Cor e Forma:PowderPeso molecular:875.09 g/molRef: 3D-II167729
Produto descontinuadoCiprofloxacin ep impurity C
CAS:Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.
Fórmula:C15H16FN3O3Pureza:Min. 95%Peso molecular:305.30 g/molRef: 3D-DEA22212
Produto descontinuadoN-Hydroxymethyl Sumatriptan
CAS:N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).
Fórmula:C15H23N3O3SPureza:Min. 95%Peso molecular:325.43 g/mol2-(2-Amino-5-bromobenzoyl)pyridine
CAS:2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval
Fórmula:C12H9BrN2OPureza:Min. 95%Peso molecular:277.12 g/molRoflumilast Impurity A
CAS:Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.
Fórmula:C16H14Cl2N2O3Pureza:Min. 95%Peso molecular:353.2 g/molSacubitril Impurity 2
CAS:Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.
Fórmula:C24H27NO4Pureza:Min. 95%Peso molecular:393.48 g/molOxacyclohexane open ring tacrolimus
CAS:Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C44H71NO13Pureza:Min. 95%Peso molecular:822.04 g/molRef: 3D-IO183660
Produto descontinuado(S)-Rabeprazole sodium
CAS:(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.
Fórmula:C18H21N3O3S•NaPureza:Min. 95%Peso molecular:382.43 g/molRef: 3D-IR183125
Produto descontinuadoPramipexole EP Impurity C
CAS:Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Fórmula:C20H32N6S2Pureza:Min. 95%(3S,4R)-Tofacitinib
CAS:(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.
Fórmula:C16H20N6OPureza:Min. 95%Peso molecular:312.37 g/molN-Desacetyl thiocolchicoside
CAS:N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.
Fórmula:C25H31NO9SPureza:Min. 95%Peso molecular:521.58 g/molRef: 3D-CHA99181
Produto descontinuadoN-Nitroso dorzolamide
N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.
Fórmula:C10H15N3O5S3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:353.44 g/molRocuronium Bromide EP Impurity F Bromide
CAS:Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.Fórmula:C34H55N2O4·BrPureza:Min. 95%Peso molecular:635.72 g/molLinagliptin impurity G
CAS:Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.
Fórmula:C25H28N8O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:472.54 g/molN-Benzyl albuterol
CAS:N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.
Fórmula:C20H27NO3Pureza:Min. 95%Peso molecular:329.4 g/molChlorthalidone impurity E
CAS:Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>
Fórmula:C14H11ClN2O3SPureza:Min. 95%Peso molecular:322.77 g/molRef: 3D-IC76330
Produto descontinuadoTriethylene glycol flufenamate
CAS:Etofenamate impurity
Fórmula:C20H22F3NO5Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:413.39 g/molRef: 3D-IT58094
Produto descontinuadoD-6-Cyano-6-norlysergic acid methyl ester
CAS:Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C17H15N3O2Pureza:Min. 95%Peso molecular:293.32 g/molRef: 3D-FBA33404
Produto descontinuadoGS 441524 triphosphate
CAS:Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.
Fórmula:C12H12N5O13P3·4NaPureza:(31P-Nmr) Min. 95 Area-%Cor e Forma:White PowderPeso molecular:531.20 g/molRef: 3D-FG167050
Produto descontinuadoAtorvastatin calcium trihydrate EP Impurity G
CAS:Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.
Fórmula:C34H37FN2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:572.67 g/mol
