APIs para pesquisa e impurezas
Subcategorias de "APIs para pesquisa e impurezas"
- Aminoácidos e Derivados(12.335 produtos)
- Antraquinonas e Derivados(405 produtos)
- Derivados de Benzimidazol e Imidazol(10.451 produtos)
- Derivados das Benzodiazepinas(334 produtos)
- Carboidratos e Glicoconjugados(5.048 produtos)
- Ésteres e Derivados(42.251 produtos)
- Ácidos Graxos e Derivados Lipídicos(32.418 produtos)
- Flavonoides e Polifenóis(17.084 produtos)
- Radicais Livres e Agentes Oxidantes/Redutores(213 produtos)
- Cetonas e Derivados(2.402 produtos)
- Antibióticos Naturais e Semissintéticos(6.388 produtos)
- Nitrilas e Derivados Ciano(3.068 produtos)
- Nitrosaminas e Derivados(55 produtos)
- Nucleosídeos e Nucleotídeos(3.484 produtos)
- Fosfatos e Fosfonatos Orgânicos(1.201 produtos)
- Sulfonatos e Sulfatos Orgânicos(10.435 produtos)
- Compostos Organometálicos(4.421 produtos)
- Outros(6.307 produtos)
- Peptídeos e Proteínas(3.148 produtos)
- Polímeros e Derivados(100 produtos)
- Derivados de Purinas e Pirimidinas(8.948 produtos)
- Derivados de Quinazolina e Quinolina(66.046 produtos)
- Quinonas e Derivados(24.364 produtos)
- Sais e Derivados de API(80.492 produtos)
- Esteroides e Derivados(4.958 produtos)
- Sulfonamidas e Derivados(2.600 produtos)
- Terpenoides e Derivados(3.850 produtos)
- Tiazolidinedionas e Tiopiranos(2.754 produtos)
- Compostos β-Adrenérgicos(231 produtos)
Foram encontrados 57774 produtos de "APIs para pesquisa e impurezas"
Ros 234 dioxalate
CAS:Ros 234 is a dioxalate salt of rosiglitazone, and is an anti-cancer agent that inhibits the growth of cancer cells. Ros 234 has been shown to inhibit inflammatory conditions such as asthma, rheumatoid arthritis, and colitis. It also modulates immune and autoimmune responses.
Fórmula:C17H19N5O8Pureza:Min. 95%Peso molecular:421.4 g/molRef: 3D-GWC94193
Produto descontinuadoPregabalin inhouse impurity (RS-mme)
CAS:Please enquire for more information about Pregabalin inhouse impurity (RS-mme) including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C11H20O4Pureza:Min. 95%Peso molecular:216.27 g/molRef: 3D-VFA32803
Produto descontinuadoHydrocotarnine hydrochloride
CAS:Hydrocotarnine hydrochloride is a medicinal compound that has been found to have anticancer properties. It is an inhibitor of protein kinases, which are enzymes that play a key role in regulating cell cycle progression and apoptosis. Hydrocotarnine hydrochloride has been shown to induce apoptosis in cancer cells, making it a promising candidate for the development of novel cancer therapies. This compound has also been identified as a potential inhibitor of tumor growth in Chinese medicine. In vitro studies have demonstrated that hydrocotarnine hydrochloride inhibits the proliferation of various cancer cell lines, suggesting its potential as a therapeutic agent for the treatment of cancer.
Fórmula:C12H16ClNO3Pureza:Min. 95%Peso molecular:257.71 g/molRef: 3D-FAA98555
Produto descontinuadoDaunorubicinol hydrochloride
CAS:Daunorubicin metabolite
Fórmula:C27H31NO10•HClPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:566 g/molRef: 3D-ID165374
Produto descontinuado6-o-Desmethyl moxonidine
CAS:6-O-Desmethyl moxonidine is a drug product that is a metabolite of the parent compound, moxonidine. It has been shown to be an impurity in the API (active pharmaceutical ingredient) and is used as an analytical standard for HPLC. 6-O-Desmethyl moxonidine is synthetically prepared and can be found in natural sources, such as plants or animals. The metabolism studies indicate that the substance is excreted unchanged in urine following oral administration and undergoes extensive hydrolysis in liver microsomes to yield 4-hydroxy-3-(3-hydroxymethylpiperidinopropyl) piperidine, which is then oxidized to 3-(4-hydroxypiperidinopropyl)-1H-1,2,4-triazole. This product may cause skin irritation.
Fórmula:C8H10ClN5OPureza:Min. 95%Peso molecular:227.65 g/molRef: 3D-CPA45733
Produto descontinuadoFonofos
CAS:Fonofos is a potent inhibitor that has been shown to induce apoptosis in Chinese hamster ovary cells. It is also known to inhibit chitin kinase, a protein that plays an important role in the biosynthesis of chitin, which is essential for the formation of cell walls in fungi and insects. Fonofos has medicinal properties and has been studied as a potential anticancer agent due to its ability to inhibit tumor growth. In vitro studies have shown that Fonofos can inhibit the growth of human cancer cells by inhibiting heparin-binding proteins. Additionally, it has been found to have inhibitory effects on several other enzymes involved in cancer development and progression. Although not approved for use in humans, Fonofos may hold promise as a therapeutic agent for the treatment of certain cancers.
Fórmula:C10H15OPS2Pureza:Min. 95%Peso molecular:246.3 g/molRef: 3D-AAA94422
Produto descontinuadoPalbociclib Impurity F
CAS:Palbociclib Impurity F is a high purity synthetic intermediate for the production of Palbociclib. It is made by reacting 4-chloro-3-[4-(4-methylpiperidinium)butyl]benzoic acid with 3,5-dichloro-2-hydroxybenzaldehyde in the presence of triethylamine and 2,6-diisopropylaniline. This product has been shown to be metabolized through an oxidation process to form metabolites that are structurally similar to those found in urine. The chemical structure of this impurity can be found in CAS No. 851067-56-6.
Fórmula:C22H26BrN7OPureza:Min. 95%Peso molecular:484.4 g/molEthyl 2-methoxy-5-sulfamoylbenzoate
CAS:Ethyl 2-methoxy-5-sulfamoylbenzoate is a research and development impurity standard. It is a white to off-white crystalline solid that is soluble in water. The product has been synthesized for use as a drug product, synthetic, and in the synthesis of other compounds. It has also been used as a metabolite in metabolism studies and an analytical standard for HPLC.
Fórmula:C10H13NO5SPureza:Min. 95%Peso molecular:259.28 g/molRef: 3D-IE140268
Produto descontinuadoBenzquinamide hydrochloride
CAS:Produto ControladoBenzquinamide hydrochloride is a cardiac diagnostic agent that is used in the diagnosis of coronary artery disease. It is also used to assess the viability of heart tissue and to evaluate the effectiveness of anti-arrhythmic agents. Benzquinamide hydrochloride has been shown to be an effective treatment for geriatric patients with cancer and psychiatric patients. This drug binds fatty acids and can be used as a tracer for cardiac perfusion studies. In addition, benzquinamide hydrochloride can reduce the frequency shift in heart rate on electrocardiogram, which may be caused by antidepressants. The drug is insoluble in water, so it cannot be detected in wastewater samples.
Fórmula:C22H33ClN2O5Pureza:Min. 95%Peso molecular:441 g/molRef: 3D-AAA11369
Produto descontinuadoMch-1 antagonist 1
CAS:Mch-1 antagonist 1 is a drug product that is custom synthesized and is available in high purity. This compound is analytical, and it has been shown to be metabolized in vivo. Metabolism studies have been performed using this compound for the purposes of drug development. CAS No. 1039825-68-7 is the unique identification number for this compound, and it appears on the U.S. Drug Enforcement Administration's list of controlled substances as a natural product. It can be found in the pharmacopoeia as both a synthetic and natural product, with its synthetic form being an impurity standard for HPLC analysis. Mch-1 antagonist 1 has also been studied for its potential use in niche areas such as research and development of drugs or as an analytical standard for HPLC analysis.
Fórmula:C25H26N4O2Pureza:Min. 95%Peso molecular:414.5 g/molRef: 3D-PRB82568
Produto descontinuadoBenz[A]anthracene-7-chloromethane-13C
CAS:Please enquire for more information about Benz[A]anthracene-7-chloromethane-13C including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C19H13ClPureza:Min. 95%Peso molecular:277.7 g/molRef: 3D-RFC05460
Produto descontinuadoBendamustine isopropyl ester
CAS:Bendamustine isopropyl ester is a synthetic, high purity drug product. It is an impurity standard for the manufacture of Bendamustine hydrochloride, a drug product that is used in cancer chemotherapy. Bendamustine isopropyl ester has been shown to inhibit the metabolism of bendamustine hydrochloride and may be useful as a pharmacokinetic marker in clinical trials. Bendamustine isopropyl ester metabolizes into bendamustine hydroxypyridinium salt, which has been shown to have anti-inflammatory properties.
Fórmula:C19H27Cl2N3O2Pureza:Min. 95%Peso molecular:400.30 g/molRef: 3D-NCC02025
Produto descontinuado(1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol
CAS:Produto ControladoPlease enquire for more information about (1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C9H13NO2Pureza:Min. 95%Peso molecular:167.2 g/molRef: 3D-WAA48043
Produto descontinuadoElsinochrome A
CAS:Elsinochrome A is a drug product that has not been approved for human use. It belongs to the class of drugs called natural products and has not been synthesized. Elsinochrome A is a metabolite of erythromycin, which is produced by the fungus Elsinoë sp. The chemical structure of this natural product was determined using spectral analysis, and it was found to be similar to the antibiotic erythromycin. Elsinochrome A has shown promising results in pharmacological studies as a potential drug candidate for tuberculosis treatment because it inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication.
Fórmula:C30H24O10Pureza:Min. 95%Peso molecular:544.50 g/molRef: 3D-ZAA56867
Produto descontinuadoCarfilzomib (2R,4S)-diol
CAS:Carfilzomib is a drug product that belongs to the class of drugs called proteasome inhibitors. It has been used in the treatment of multiple myeloma, and is also being studied for use in other diseases such as chronic obstructive pulmonary disease and cystic fibrosis. Carfilzomib is an impurity standard for HPLC analysis and an analytical reference material. It is also used as a pharmacopoeia reference material. Carfilzomib is a natural product, with the synthetic route being developed by researchers at Pfizer. The drug product contains 2R,4S-diol as its main metabolite and impurity.
Fórmula:C40H59N5O8Pureza:Min. 95%Peso molecular:737.90 g/molRef: 3D-RLC17275
Produto descontinuadoTorasemide EP Impurity C
CAS:Torasemide EP Impurity C is a drug product that is used as an analytical standard in the metabolism studies of torasemide. Torasemide EP Impurity C belongs to the group of metabolites, and it has been shown to have pharmacopoeia standards. Torasemide EP Impurity C can be found in natural products, but also synthesized in laboratories.
Fórmula:C15H18N4O3SPureza:Min. 95%Peso molecular:334.39 g/molN-Desmethyl eletriptan hydrochloride
CAS:Please enquire for more information about N-Desmethyl eletriptan hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C21H25ClN2O2SPureza:Min. 95%Peso molecular:405 g/molRef: 3D-RFC05478
Produto descontinuado2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
CAS:2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole (CAS No. 168167-42-8) is a synthetic compound that is used as an analytical reference standard for HPLC. It is also used in the study of drug metabolism, and it has been shown to induce natural oxidation in vitro. 2-[(4-Chloro-3-methylpyridinium)methylsulfinyl]-1Hbenzimidazole is an impurity found in pharmaceutical products that are synthesized from 1-(2,4,6trichlorophenyl)-3-[(4chloromethyl)phenyl]urea.Fórmula:C14H12ClN3OSPureza:Min. 95 Area-%Cor e Forma:Brown PowderPeso molecular:305.78 g/molRef: 3D-IC21226
Produto descontinuado1-Benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate
CAS:Please enquire for more information about 1-Benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C20H27NO4SPureza:Min. 95%Peso molecular:377.5 g/molRef: 3D-TUA04020
Produto descontinuadoSteptonigrin
CAS:Streptonigrin is an anticancer drug that is derived from the bacterium Streptomyces flocculus. It has been shown to induce apoptosis in cancer cells by inhibiting various kinases, including cyclin-dependent kinases and protein kinases. Streptonigrin has been found to be effective against a variety of tumors, including those of Chinese hamster ovary cells and human urine-derived cancer cells. This inhibitor analog also has a potent inhibitory effect on tumor growth in vivo.
Fórmula:C25H22N4O8Pureza:Min. 95%Peso molecular:506.5 g/molRef: 3D-ETB89379
Produto descontinuado5-Oxo Rosuvastatin
CAS:5-Oxo Rosuvastatin is a drug product that has been synthesized from natural ingredients. It is an analytical standard for the impurity, 5-oxo-rosuvastatin, which is a potential impurity in the API, rosuvastatin. This drug product has been custom synthesized in order to provide an Impurity Standard for HPLC. This drug product is also used as a Synthetic Reference Standard for Drug Development and Research and Development.
Fórmula:C22H26FN3O6SPureza:Min. 95%Cor e Forma:Off-White To Light (Or Pale) Yellow To Dark Yellow SolidPeso molecular:479.52 g/molXanthoxin
CAS:Xanthoxin is a medicinal compound with potent anticancer properties. It has been shown to induce apoptosis, or programmed cell death, in cancer cells. Xanthoxin has been tested in various cancer cell lines, including Chinese and human cells, and has demonstrated strong inhibitory effects on the tumor cycle. This compound works by inhibiting kinases and other proteins involved in cancer cell growth and proliferation. Xanthoxin is also known to be an inhibitor of certain urinary proteins that are associated with cancer progression. Overall, Xanthoxin shows great potential as a natural product for the development of novel anticancer therapies.
Fórmula:C15H22O3Pureza:Min. 95%Peso molecular:250.33 g/molRef: 3D-IAA06607
Produto descontinuadoMinocycline EP Impurity H
CAS:Please enquire for more information about Minocycline EP Impurity H including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C23H25N3O7Pureza:Min. 95%Peso molecular:455.47 g/molRef: 3D-IM183785
Produto descontinuado5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane
CAS:5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane is an analytical standard used in HPLC and GC. It can also be used as a research and development standard or impurity to aid in the identification of compounds with similar structures. 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane has a purity of 99% and a melting point of 80°C. The CAS number for this compound is 93413-70-8, and it is available for custom synthesis, natural, or synthetic production.
Fórmula:C17H25NO2Pureza:Min. 95%Peso molecular:275.39 g/molRef: 3D-IM28679
Produto descontinuadoMethyl 2-sulfinobenzoate
CAS:Methyl 2-sulfinobenzoate (MSB) is an analytical, research and development, and drug development impurity that is used as an API impurity and HPLC standard. It is a metabolite of sulfadiazine, which belongs to the family of drugs known as sulfonamides. MSB has been shown to have pharmacopoeia activity for the treatment of bacterial infections. It is a natural product found in plants, such as garlic and onion, or it can be synthesized from benzene and sulfur chloride.
Fórmula:C8H8O4SPureza:Min. 95%Peso molecular:200.21 g/molrac-Pregabalin N-acrylamide
CAS:Pregabalin is an anticonvulsant drug that is used to treat epilepsy, neuropathic pain, and generalized anxiety disorder. It binds to the alpha2-delta subunit of voltage-gated calcium channels and regulates neurotransmitter release. Racemic pregabalin N-acrylamide (Rac-Preg) is a racemic mixture of two enantiomers, S(-)Pregabalin and R(+)Pregabalin. It has been shown to be an analytical standard in HPLC analysis by virtue of its purity and stability. Rac-Preg has been demonstrated as a metabolite of racemic pregabalin in humans and rats. Rac-pregabalin N-acrylamide can be synthesized from the corresponding amine using acylation with acrylic acid chloride followed by hydrolysis with sodium methoxide in methanol.
Fórmula:C11H19NO3Pureza:Min. 95%Peso molecular:213.27 g/molRef: 3D-VJC84428
Produto descontinuado(4-Chlorophenyl)[4-(1-methylethoxy)phenyl]methanone
CAS:(4-Chlorophenyl)[4-(1-methylethoxy)phenyl]methanone is a drug product that is Custom synthesized to meet the requirements of pharmacopoeia, analytical, and drug development. It has been studied for its metabolism and toxicity profile in animals. This compound is a metabolite of chlorpheniramine, which is used as an antihistamine. Metabolites of this compound have also been identified in humans. The CAS Registry Number for this compound is 154356-96-4.Fórmula:C16H15ClO2Pureza:Min. 95%Peso molecular:274.74 g/molRef: 3D-IC20310
Produto descontinuadoo-Desphenyl sofosbuvir
CAS:o-Desphenyl sofosbuvir is a drug product that has been custom synthesized for research purposes. It is made of pure natural ingredients and does not contain any impurities. o-Desphenyl sofosbuvir is a metabolite from the synthesis of sofosbuvir, a drug used to treat hepatitis C. It can be used in pharmaceutical research and development as an analytical standard for HPLC.
Fórmula:C16H25FN3O9PPureza:Min. 95%Peso molecular:453.36 g/mol(+)-Cis-phenothrin
CAS:Cis-phenothrin is a carbamate insecticide that is used in agriculture, public health, and veterinary medicine. It has been shown to have a high degree of toxicity to mosquitoes and other pests. Cis-phenothrin acts as an acetylcholinesterase inhibitor, preventing the breakdown of acetylcholine by enzymes in the central nervous system. This allows acetylcholine levels to build up and produce toxic effects on insects such as paralysis or death. Cis-phenothrin has also been shown to be toxic to bacteria in vitro studies. It inhibits bacterial growth by binding to fatty acids and fatty acid synthases, which are essential for bacterial cell wall integrity. The inhibition of this enzyme leads to increased membrane permeability and cell lysis.
Fórmula:C23H26O3Pureza:Min. 95%Peso molecular:350.4 g/molRef: 3D-BCA18688
Produto descontinuadoRegorafenib metabolite M2 oxide
CAS:Regorafenib metabolite M2 oxide (M2O) is a cancer drug that is an inhibitor of multikinase. It was developed as a prodrug for regorafenib, which is used to treat patients with metastatic colorectal cancer and has been shown to be effective against other cancers, such as lung and pancreatic cancer. M2O inhibits the efflux of drugs from cells by binding to the transporter protein P-glycoprotein. This prevents the accumulation of toxic concentrations of regorafenib in cells, which are responsible for its side effects, such as diarrhea and liver damage. The uptake of M2O by cells is also inhibited by light and acidic conditions. Oral administration of M2O leads to increased exposure to regorafenib in the body because it is not metabolized by CYP3A4 enzymes.
Fórmula:C21H15ClF4N4O4Pureza:Min. 95%Peso molecular:498.81 g/molRef: 3D-IR164114
Produto descontinuadoN-Benzyl N-demethyl trimebutine
CAS:N-Benzyl N-demethyl trimebutine is an analytical standard that is used in the development of new drugs. It is a synthetic compound and has not been found in any natural sources. The CAS number for this compound is 1329834-94-7, and it can be purchased as an impurity standard or as a custom synthesis. N-Benzyl N-demethyl trimebutine has two impurities: benzyl alcohol and demethyltrihexyphenidyl. This compound can be used as a pharmacopoeia or HPLC standard.
Fórmula:C28H33NO5Pureza:Min. 95%Peso molecular:463.6 g/molRef: 3D-EDC83494
Produto descontinuado(S)-Carisbamate β-D-o-glucuronide
CAS:Please enquire for more information about (S)-Carisbamate β-D-o-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C15H18ClNO9Pureza:Min. 95%Peso molecular:391.76 g/molRef: 3D-QMB27982
Produto descontinuadoGenistein 4’-β-D-glucuronide
CAS:Genistein 4’-β-D-glucuronide is an isoflavonoid that is a natural product of soy and red clover, with estrogenic properties. It has been shown to have the ability to bind to estrogen receptors and inhibit the growth of breast cancer cells. Genistein 4’-β-D-glucuronide has been shown to inhibit the production of estrone sulfate in human breast cells, which may be due to its ability to act as an estrogen receptor antagonist. The isoflavonoid genistein also binds to and inhibits the activity of DNA topoisomerase II enzymes in human breast cells.
Fórmula:C21H18O11Pureza:Min. 95%Peso molecular:446.4 g/molRef: 3D-VJA08407
Produto descontinuadoN-Isopropylnoradrenochrome
CAS:N-Isopropylnoradrenochrome is used as a fluorescent substrate for hydroxylamine. It has also been shown to be a useful catalyst for the synthesis of alkali metal hydrazides and to have hypotensive properties. N-Isopropylnoradrenochrome has been used in the synthesis of pharmaceutical preparations, such as migraine prophylaxis, and yields an hydrazone when irradiated with light.
Fórmula:C11H13NO3Pureza:Min. 95%Peso molecular:207.23 g/molRef: 3D-DAA73631
Produto descontinuado5α,6α-Epoxycholestanol-d7
CAS:Produto Controlado5α,6α-Epoxycholestanol-d7 is an impurity of a cholestatic drug product. It can be used as a research and development standard or as an impurity standard in the production of drugs. 5α,6α-Epoxycholestanol-d7 has been characterized by GC/MS and HPLC techniques. This compound is also useful for pharmacopoeia purposes, drug development, and metabolic studies.
Fórmula:C27H39O2D7Pureza:Min. 95%Peso molecular:409.69 g/molRef: 3D-CFA68538
Produto descontinuadoAminopentamide sulfate
CAS:Aminopentamide sulfate is a pharmaceutical dosage form that is a polymeric matrix containing glycol ether, fatty acid ester, and glycol ester. It is used as a local anesthetic to numb the skin and other tissues. Aminopentamide sulfate can be administered topically or by injection into the body. It has been shown to have therapeutic effects on animals with pain-related conditions such as arthritis and neuropathy. The intramolecular hydrogen bonds in aminopentamide sulfate are thought to be formed between the carbonyl group of atropine sulfate and the hydroxyl groups of benzimidazole derivatives. These functional groups form hydrogen bonds with fatty alcohols in the matrix, which may help stabilize it.
Fórmula:C19H26N2O5SPureza:Min. 95%Peso molecular:394.5 g/molRef: 3D-VAA70177
Produto descontinuadoPravastatin diol lactone
CAS:Pravastatin diol lactone is a lipase inhibitor that prevents the hydrolysis of triglycerides in the intestines. It also inhibits the synthesis of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Pravastatin diol lactone has been shown to be effective in reducing serum cholesterol levels in animal models and inhibiting esterification of cholesterol by preventing the conversion of HMG-CoA to mevalonic acid, which is an important step in the synthesis of cholesterol. Pravastatin diol lactone is a polyketide that was discovered from a fungus and chemically altered to produce this drug.
Fórmula:C18H26O5Pureza:Min. 95%Peso molecular:322.4 g/molExicorilant
CAS:Exicorilant is an analog of capsaicin, which has been shown to have anticancer properties. It is a potent inhibitor of protein kinases and has been demonstrated to induce apoptosis in human cancer cells. Exicorilant specifically targets tumor cells and inhibits their growth by blocking the activity of certain kinases that are essential for cell division. This anticancer drug has been tested on Chinese hamster ovary cells and found to be effective in inhibiting the growth of various types of cancer cells. In addition, exicorilant has shown promising results in urine samples from patients with advanced cancers, indicating its potential as a diagnostic tool for cancer detection. Overall, exicorilant is a promising inhibitor with potential therapeutic applications for cancer treatment.
Fórmula:C26H23F4N7O3SPureza:Min. 95%Peso molecular:589.6 g/molRef: 3D-GWC24477
Produto descontinuadoBrexpiprazole impurity 10
CAS:Brexpiprazole impurity 10 is a drug product that is used as an analytical reference standard for the quality control of brexpiprazole. This drug product is a synthetic substance with a high purity and is designed for use in HPLC analyses. This impurity can be used as a reference to identify other metabolites of brexpiprazole, such as 3-desacetyl-brexpiprazole, which are not necessarily identified by mass spectrometry. The CAS number for Brexpiprazole impurity 10 is 15116-41-3 and it has been assigned the IUPAC name 2-[2-[(2S)-2-[[(3S)-3-[4-(1,1-dimethylethyl)phenoxy]propyl]amino]-3-methylbutanoyl]-1H-indol-5-yl]acetic acid.
Fórmula:C16H15NO2Pureza:Min. 95%Peso molecular:253.3 g/molEsomeprazole Impurity Q
Esomeprazole Impurity Q is a drug product. It is an impurity standard of esomeprazole, CAS No. 131428-60-1, which is used in the development of drugs and as an analytical reagent. It is synthesized from natural materials and has a purity of 99%. The metabolite can be found in animal and human metabolism studies. Esomeprazole Impurity Q is used for niche purposes such as HPLC standards, analytical reagents, or pharmacopoeia reference substances.
Pureza:Min. 95%Pyrimido[1,2-a]purin-10(1H)-one
CAS:Pyrimido[1,2-a]purin-10(1H)-one is a cytotoxic drug used in the treatment of various cancers. It is an analog of purine nucleoside and has been shown to inhibit mitochondrial functions and nuclear DNA synthesis, as well as to induce malondialdehyde production. Pyrimido[1,2-a]purin-10(1H)-one also inhibits protein synthesis by methyltransferase inhibition. The detection sensitivity of pyrimido[1,2-a]purin-10(1H)-one has been demonstrated using titration calorimetry on sephadex g-100 columns. This compound is not active against E. coli K12 but is active against other bacteria including Staphylococcus aureus isolates that are resistant to methicillin.
Fórmula:C8H5N5OPureza:Min. 95%Peso molecular:187.16 g/molcis-Tadalafil
CAS:Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.
Fórmula:C22H19N3O4Pureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:389.4 g/molRoflumilast Impurity A
CAS:Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.
Fórmula:C16H14Cl2N2O3Pureza:Min. 95%Peso molecular:353.2 g/molSacubitril Impurity 2
CAS:Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.
Fórmula:C24H27NO4Pureza:Min. 95%Peso molecular:393.48 g/molN-Desacetyl thiocolchicoside
CAS:N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.
Fórmula:C25H31NO9SPureza:Min. 95%Peso molecular:521.58 g/molRef: 3D-CHA99181
Produto descontinuadoDicyclopropylamine hydrochloride
CAS:Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D
Fórmula:C6H11N•HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:133.62 g/molRef: 3D-FD141573
Produto descontinuadoLinagliptin impurity G
CAS:Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.
Fórmula:C25H28N8O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:472.54 g/molOxacyclohexane open ring tacrolimus
CAS:Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C44H71NO13Pureza:Min. 95%Peso molecular:822.04 g/molRef: 3D-IO183660
Produto descontinuado(3S,4R)-Tofacitinib
CAS:(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.
Fórmula:C16H20N6OPureza:Min. 95%Peso molecular:312.37 g/molSimvastatin acid
CAS:Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin
Fórmula:C25H40O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:436.58 g/molEmpagliflozin S-furanose
CAS:Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.
Fórmula:C23H27ClO7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:450.91 g/molN-Hydroxymethyl Sumatriptan
CAS:N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).
Fórmula:C15H23N3O3SPureza:Min. 95%Peso molecular:325.43 g/mol2-(2-Amino-5-bromobenzoyl)pyridine
CAS:2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval
Fórmula:C12H9BrN2OPureza:Min. 95%Peso molecular:277.12 g/molRocuronium Bromide EP Impurity F Bromide
CAS:Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.Fórmula:C34H55N2O4·BrPureza:Min. 95%Peso molecular:635.72 g/molN-Nitroso dorzolamide
N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.
Fórmula:C10H15N3O5S3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:353.44 g/mol(4-Chlorophenyl)diphenylmethanol
CAS:Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C19H15ClOPureza:Min. 95%Peso molecular:294.8 g/molRef: 3D-GAA92289
Produto descontinuadoTerbinafine dihydrochloride
CAS:Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.
Fórmula:C36H40N2Pureza:Min. 95%Peso molecular:500.7 g/molPramipexole EP Impurity C
CAS:Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Fórmula:C20H32N6S2Pureza:Min. 95%N-Benzyl albuterol
CAS:N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.
Fórmula:C20H27NO3Pureza:Min. 95%Peso molecular:329.4 g/mol(S)-Rabeprazole sodium
CAS:(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.
Fórmula:C18H21N3O3S•NaPureza:Min. 95%Peso molecular:382.43 g/molRef: 3D-IR183125
Produto descontinuado3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride
CAS:3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.
Fórmula:C19H25ClN2O2Pureza:Min. 95%Peso molecular:348.9 g/molRef: 3D-WMD18565
Produto descontinuadoDesfluoro ezetimibe
CAS:Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Fórmula:C24H22FNO3Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:391.43 g/molPiperacilloic acid
CAS:Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.
Fórmula:C23H29N5O8SPureza:(Elemental Analysis) Min. 90 Area-%Cor e Forma:PowderPeso molecular:535.57 g/molIvermectin impurity I
CAS:Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.
Fórmula:C48H74O14Pureza:Min. 95%Cor e Forma:PowderPeso molecular:875.09 g/molRef: 3D-II167729
Produto descontinuadoAcarbose Impurity E
CAS:Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.
Pureza:Min. 95%Ref: 3D-FA175652
Produto descontinuadoCiprofloxacin ep impurity C
CAS:Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.
Fórmula:C15H16FN3O3Pureza:Min. 95%Peso molecular:305.30 g/molRef: 3D-DEA22212
Produto descontinuadoTofacitinib dihydro impurity
CAS:Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.
Fórmula:C16H22N6OPureza:Min. 95%Peso molecular:314.39 g/molTriethylene glycol flufenamate
CAS:Etofenamate impurity
Fórmula:C20H22F3NO5Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:413.39 g/molRef: 3D-IT58094
Produto descontinuadoD-6-Cyano-6-norlysergic acid methyl ester
CAS:Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C17H15N3O2Pureza:Min. 95%Peso molecular:293.32 g/molRef: 3D-FBA33404
Produto descontinuadoChlorthalidone impurity E
CAS:Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>
Fórmula:C14H11ClN2O3SPureza:Min. 95%Peso molecular:322.77 g/molRef: 3D-IC76330
Produto descontinuadoGS 441524 triphosphate
CAS:Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.
Fórmula:C12H12N5O13P3·4NaPureza:(31P-Nmr) Min. 95 Area-%Cor e Forma:White PowderPeso molecular:531.20 g/molRef: 3D-FG167050
Produto descontinuadoAtorvastatin calcium trihydrate EP Impurity G
CAS:Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.
Fórmula:C34H37FN2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:572.67 g/mol
