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APIs para pesquisa e impurezas

APIs para pesquisa e impurezas

Os Ingredientes Farmacêuticos Ativos (APIs) são as substâncias nos medicamentos responsáveis por seus efeitos terapêuticos. Nesta seção, você encontrará uma ampla variedade de APIs destinados a uso em pesquisa. Esses compostos são essenciais para o desenvolvimento, teste e validação de novas formulações farmacêuticas. Na CymitQuimica, oferecemos APIs de alta qualidade para apoiar a pesquisa em descoberta e desenvolvimento de medicamentos.

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  • Maraviroc-d6

    CAS:
    <p>Maraviroc-d6 is a medicinal compound that has been developed as an inhibitor of kinases, which are enzymes involved in cell cycle regulation and apoptosis. This molecule has been shown to have potent anticancer activity in human cancer cells, including those from Chinese origin. Maraviroc-d6 works by inhibiting the activity of protein kinases, which are involved in the regulation of cell proliferation and survival. This inhibition leads to the induction of apoptosis, or programmed cell death, in cancer cells. Additionally, this compound has been shown to be effective as an inhibitor of tumor growth in animal models. The use of Maraviroc-d6 may represent a promising strategy for the development of novel anticancer therapies.</p>
    Fórmula:C29H41F2N5O
    Pureza:Min. 95%
    Peso molecular:519.7 g/mol

    Ref: 3D-IRB69922

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  • Piquindone

    CAS:
    <p>Piquindone is a medicinal compound that has shown promising anticancer properties in human tumor cells. It acts as an inhibitor of protein kinases, which are enzymes that regulate cell growth and division. Piquindone is an analog of a natural product found in Chinese urine and has been studied for its ability to induce apoptosis, or programmed cell death, in cancer cells. This compound has shown potent activity against various types of cancer cells and may have potential as a therapeutic agent for the treatment of cancer. Its mechanism of action involves the inhibition of specific kinases involved in cancer cell proliferation and survival. Piquindone is being investigated further for its potential as a cancer cell inhibitor.</p>
    Fórmula:C15H22N2O
    Pureza:Min. 95%
    Peso molecular:246.35 g/mol

    Ref: 3D-DDA54197

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  • 2-Methoxy-5-methyl-gamma-phenylbenzenepropanol

    CAS:
    <p>2-Methoxy-5-methyl-gamma-phenylbenzenepropanol is a synthetic compound that is used as an intermediate in the synthesis of coumarin derivatives. Reaction with sulfonating agents produces sulfones, and reaction with borohydride reagents produces boronates. The synthesis of 2-methoxy-5-methyl-gamma-phenylbenzenepropanol can be accomplished by the reduction of diphenyl ethers with lithium aluminum hydride or borohydride. The reduction can also be carried out using lanthanum oxide and potassium borohydride. The reaction proceeds smoothly at room temperature in nonpolar solvents.<br>2-Methoxy-5-methyl-gamma-phenylbenzenepropanol reacts with chloride to produce the corresponding chlorides, which are useful intermediates for the synthesis of tolterodine tartrate, a drug used to treat urinary inc</p>
    Fórmula:C17H20O2
    Pureza:Min. 95%
    Peso molecular:256.34 g/mol

    Ref: 3D-IM145669

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  • Phenproxide

    CAS:
    <p>Phenproxide is an analog of testosterone that has been used traditionally in Chinese medicine to treat tumors. It has been found to induce apoptosis in cancer cells by inhibiting kinases, which are enzymes that regulate cellular processes such as cell division and growth. Phenproxide has also been shown to inhibit the activity of somatostatin, a hormone that regulates the release of other hormones. This inhibition may contribute to its anti-cancer properties. In addition, Phenproxide has been shown to have an effect on hyaluronan metabolism, a substance involved in tissue repair and inflammation. It is excreted in urine and may be used as a potential biomarker for cancer diagnosis or monitoring.</p>
    Fórmula:C15H14ClNO4S
    Pureza:Min. 95%
    Peso molecular:339.8 g/mol

    Ref: 3D-ZBA82875

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  • 2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole

    CAS:
    <p>2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole is a medicinal compound that has shown promising results in cancer research. It works as an inhibitor of cyclin-dependent kinases, which are essential for cancer cell proliferation. This compound induces apoptosis in cancer cells by inhibiting the activity of certain proteins involved in tumor growth. Studies have shown that 2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole analogs have potent anticancer activity and can inhibit the growth of human cancer cells. This compound has also been found to be present in urine samples from Chinese patients with cancer. Further research on this compound may lead to the development of new and effective treatments for various types of cancers.</p>
    Fórmula:C14H14N2
    Pureza:Min. 95%
    Peso molecular:210.27 g/mol

    Ref: 3D-XAA12667

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  • Fonofos

    CAS:
    <p>Fonofos is a potent inhibitor that has been shown to induce apoptosis in Chinese hamster ovary cells. It is also known to inhibit chitin kinase, a protein that plays an important role in the biosynthesis of chitin, which is essential for the formation of cell walls in fungi and insects. Fonofos has medicinal properties and has been studied as a potential anticancer agent due to its ability to inhibit tumor growth. In vitro studies have shown that Fonofos can inhibit the growth of human cancer cells by inhibiting heparin-binding proteins. Additionally, it has been found to have inhibitory effects on several other enzymes involved in cancer development and progression. Although not approved for use in humans, Fonofos may hold promise as a therapeutic agent for the treatment of certain cancers.</p>
    Fórmula:C10H15OPS2
    Pureza:Min. 95%
    Peso molecular:246.3 g/mol

    Ref: 3D-AAA94422

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  • Acrolein-d4

    CAS:
    <p>Please enquire for more information about Acrolein-d4 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C3H4O
    Pureza:Min. 95%
    Peso molecular:60.09 g/mol

    Ref: 3D-IBA98405

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  • aR453588

    CAS:
    <p>aR453588 is a human analog of Voriconazole, which has been found to have anticancer properties. This compound is a kinase inhibitor that works by inducing apoptosis in cancer cells. It has been shown to be effective against various types of tumors, including those resistant to other inhibitors. aR453588 also inhibits the growth of cancer cells by blocking protein synthesis and cell division. This compound is derived from cellulose and can be detected in urine samples after administration. Overall, aR453588 shows great promise as a potential treatment for cancer.</p>
    Fórmula:C25H25N7O2S2
    Pureza:Min. 95%
    Peso molecular:519.6 g/mol

    Ref: 3D-QSB60900

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  • L-Isoleucine orlistat

    CAS:
    <p>L-Isoleucine orlistat is a drug product that is an analytical standard and a natural product. It is used in research and development for the study of drug metabolism, and as an impurity standard for synthetic L-isoleucine. L-Isoleucine orlistat has CAS number 1072902-75-0 and Impurity Standard Number (ISN) 910.<br>L-Isoleucine orlistat is not a registered active pharmaceutical ingredient (API). It can be custom synthesized to meet the requirements of a particular application, such as high purity, pharmacopoeia grade, or USP HPLC grade.</p>
    Fórmula:C29H53NO5
    Pureza:Min. 95%
    Peso molecular:495.7 g/mol

    Ref: 3D-XSB90275

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  • Salmeterol Dimer Impurity (Mixture of Diastereomers)

    CAS:
    <p>Salmeterol dimer impurity is a drug product. It is a custom synthesis with high purity. The metabolite of this compound is salmeterol, which is an active ingredient in the asthma medication Serevent (salmeterol xinafoate). Salmeterol dimer impurity has been shown to be a natural metabolite of salmeterol. Salmeterol dimer impurity has also been shown to have anti-inflammatory properties. This compound can be found as an analytical standard for HPLC and used for research and development purposes.</p>
    Fórmula:C50H72N2O7
    Pureza:Min. 95%
    Peso molecular:812.53395

    Ref: 3D-FS178211

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  • Emtricitabine impurity 17

    CAS:
    <p>Please enquire for more information about Emtricitabine impurity 17 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C8H10FN3O4S
    Pureza:Min. 95%
    Peso molecular:263.24 g/mol

    Ref: 3D-IE183412

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  • Amlodipine EP Impurity F maleate

    CAS:
    <p>Amlodipine EP Impurity F maleate is an impurity of amlodipine, a drug product. It is a natural substance that has been classified as an API impurity in the United States Pharmacopeia (USP). The chemical name for this drug is 3-(2-chlorophenyl)-1-methyl-5-(o-tolyloxy)-2,4-dihydro-6H-[1,3]thiazolo[3,2-a]pyrimidin-7-one. Amlodipine EP Impurity F maleate has the following properties: C12H9ClNO2S and a melting point of 210°C with a purity of 99.5%. This compound was synthesized by custom synthesis and is used as an analytical standard for HPLC. This compound was also used during the development of amlodipine to determine its metabolism studies.</p>
    Fórmula:C19H23ClN2O5•C4H4O4
    Pureza:Min. 95%
    Peso molecular:510.92 g/mol

    Ref: 3D-IA182779

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  • Amiodarone impurity E

    CAS:
    <p>Amiodarone impurity E is a nucleophilic compound that is synthesized by the acylation of a diazonium salt with an amine. It has been shown to be active against staphylococci, but not against subtilis. The reaction may be catalyzed by acid or chloride. Amiodarone impurity E is also demethylated and dehydrated to form the final product, amiodarone.</p>
    Fórmula:C19H18O3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:294.34 g/mol

    Ref: 3D-IA63609

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  • Sitagliptin monohydrochloride monohydrate

    CAS:
    <p>Sitagliptin monohydrochloride monohydrate is an inhibitor of dipeptidyl peptidase-4 (DPP-4), which is responsible for the degradation of incretin hormones. It is used in the treatment of type 2 diabetes mellitus, as it increases insulin secretion and reduces blood glucose levels. Recent studies have shown that Sitagliptin has anticancer properties, as it induces apoptosis in cancer cells. It also inhibits protein kinases, which are involved in tumor growth and metastasis. Capsaicin, a compound found in chili peppers, has been shown to enhance the anticancer activity of Sitagliptin in Chinese hamster ovary cells. The drug is excreted primarily through urine and has a low potential for drug interactions with other kinase inhibitors. Overall, Sitagliptin monohydrochloride monohydrate shows great promise as both a diabetes medication and an anticancer agent.</p>
    Fórmula:C16H18ClF6N5O2
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:461.79 g/mol

    Ref: 3D-MJB15692

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  • 7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole

    CAS:
    <p>7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole (7'-MPB) is a benzimidazole derivative that is used as a medicine. It is made from recycled chemicals and has shown to have industrial applications as a catalyst for cyclization reactions. 7'-MPB is also used in the production of benzenesulfonic acid, which is an organic solvent. This chemical has been shown to be effective against high blood pressure, but has not been tested on humans yet. Telmisartan, which belongs to the angiotensin II receptor blocker class of drugs, can inhibit the synthesis of prostaglandins.</p>
    Fórmula:C18H18N4
    Pureza:Min. 95%
    Peso molecular:290.36 g/mol

    Ref: 3D-IM25660

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  • 2,2',4,4',6,6'-Hexachlorobiphenyl

    Produto Controlado
    CAS:
    <p>2,2',4,4',6,6'-Hexachlorobiphenyl (PCB-136) is a potent anticancer agent that has been shown to induce apoptosis in cancer cells. It acts as a kinase inhibitor by blocking the activity of specific kinases involved in tumor growth and progression. PCB-136 has been studied extensively in human and Chinese hamster ovary cells and has been found to be highly effective against various types of cancer. This medicinal analog also exhibits inhibitory effects on the protein kinases that regulate cell division and proliferation, making it a promising candidate for cancer therapy. In addition, PCB-136 shows potential for use as a urinary biomarker for exposure to environmental pollutants due to its persistence in the environment and ability to accumulate in body tissues.</p>
    Fórmula:C12H4Cl6
    Pureza:Min. 95%
    Peso molecular:360.9 g/mol

    Ref: 3D-IBA97903

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  • (-)-Sabinene

    CAS:
    <p>(-)-Sabinene is a natural compound found in urine and various medicinal plants, including Chinese herbs. It has been identified as an analog of another natural compound that exhibits potent anticancer activity. (-)-Sabinene has been shown to inhibit the activity of certain proteins involved in cell cycle regulation and apoptosis, which are important processes for the growth and survival of cancer cells. In addition, (-)-Sabinene has been found to have inhibitory effects on tumor kinase activity, making it a promising candidate for the development of new anticancer drugs. Studies have shown that (-)-Sabinene can effectively inhibit the growth of various types of cancer cells, making it a potential therapeutic agent for the treatment of cancer.</p>
    Fórmula:C10H16
    Pureza:Min. 95%
    Cor e Forma:Clear Liquid
    Peso molecular:136.23 g/mol

    Ref: 3D-KAA40816

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