APIs para pesquisa e impurezas

<p>SLMP53-1 is an anticancer agent that has been shown to induce apoptosis in cancer cells. It works by inhibiting kinases, which are enzymes involved in cell signaling pathways that regulate cell growth and division. SLMP53-1 has been found to be effective against a variety of tumors, including those of the bladder, breast, and lung. In addition, it has shown promising results as a potential treatment for Chinese hamster ovary (CHO) cells and human cancer cell lines. SLMP53-1 is also an analog of hepcidin, a protein that regulates iron metabolism in the body. Its unique structure allows it to bind specifically to cancer cells without affecting healthy cells, making it a promising candidate for targeted cancer therapy.</p>

<p>2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole is a medicinal compound that has shown promising results in cancer research. It works as an inhibitor of cyclin-dependent kinases, which are essential for cancer cell proliferation. This compound induces apoptosis in cancer cells by inhibiting the activity of certain proteins involved in tumor growth. Studies have shown that 2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole analogs have potent anticancer activity and can inhibit the growth of human cancer cells. This compound has also been found to be present in urine samples from Chinese patients with cancer. Further research on this compound may lead to the development of new and effective treatments for various types of cancers.</p>

<p>aR453588 is a human analog of Voriconazole, which has been found to have anticancer properties. This compound is a kinase inhibitor that works by inducing apoptosis in cancer cells. It has been shown to be effective against various types of tumors, including those resistant to other inhibitors. aR453588 also inhibits the growth of cancer cells by blocking protein synthesis and cell division. This compound is derived from cellulose and can be detected in urine samples after administration. Overall, aR453588 shows great promise as a potential treatment for cancer.</p>

<p>3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide is an analytical standard, used for HPLC analysis of impurities. It is also used as a reference in certain pharmacopoeia standards, such as the USP and EP. 3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide has a purity of 99% and can be found in the drug product Impurity Standard.</p>

<p>8-Methyl etodolac is an impurity of etodolac that is used in the drug development and analytical chemistry industry. It is a synthetic metabolite of etodolac, which is an analgesic agent that belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). 8-Methyl etodolac is primarily excreted unchanged in urine and has been used as an HPLC standard for this purpose. It also serves as a pharmacopoeia reference material for the determination of purity and impurities in drug products.</p>

<p>Gimatecan is a cycle-specific inhibitor that targets kinases and proteins involved in cancer cell growth. It is a medicinal compound that has been shown to be effective against various types of human cancers. Gimatecan works by inhibiting the activity of protein kinases, which are enzymes that promote cell division and proliferation. This inhibition leads to apoptosis, or programmed cell death, in tumor cells. Gimatecan has been tested extensively in Chinese hamster ovary cells and has demonstrated potent anticancer activity. The compound is excreted primarily through urine and has shown promising results as an anticancer agent in preclinical studies.</p>

<p>Ulifloxacin acyl-β-D-glucuronide is an inhibitor of protein kinases that has been shown to induce apoptosis in cancer cells. This compound is a metabolite of ulifloxacin, a fluoroquinolone antibiotic used to treat urinary tract infections. Ulifloxacin acyl-β-D-glucuronide has potent anticancer activity and has been shown to inhibit the growth of tumor cells in vitro. This compound is an analog of other kinase inhibitors and has been extensively studied in Chinese hamster ovary (CHO) cells, where it was found to be effective against various types of cancer. Ulifloxacin acyl-β-D-glucuronide also possesses toxin-binding properties and may have potential as an anti-toxin agent.</p>

<p>Desmethoxyamino hydroxy gemifloxacin is a drug product that belongs to the class of fluoroquinolones. It is a synthetic compound with a molecular weight of 551.4 g/mol and an empirical formula of C21H25FN3O2. Desmethoxyamino hydroxy gemifloxacin has been shown to inhibit bacterial DNA gyrase and topoisomerase IV in vitro, which are enzymes that maintain the integrity of bacterial DNA. The compound binds to 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. This drug product is metabolized into gemifloxacin, desmethoxyamino acid, and desmethylgemifloxacin. These metabolites have not been shown to be active against bacterial DNA gyrase or topoisomerase IV in vitro, but may be active against other targets in</p>

<p>NUC-7738 is a medicinal compound that has been shown to be an effective inhibitor of cyclin-dependent kinases (CDKs). It has potent anticancer activity and has been studied extensively in Chinese hamster ovary (CHO) cells, human leukemia cells, and other cancer cell lines. NUC-7738 works by selectively inhibiting CDK4/6, which are critical regulators of the cell cycle. This leads to the induction of apoptosis in cancer cells, making it a promising new therapeutic agent for the treatment of various types of cancer. Additionally, NUC-7738 has been shown to have low toxicity and good pharmacokinetic properties in preclinical studies. Overall, this compound holds great promise as a novel anticancer therapy that may help improve outcomes for patients with cancer.</p>

<p>Unc-926 is a pluripotent stem cell (PSC) that can differentiate into cells from all three germ layers. Unc-926 cells have been shown to be glucose-dependent and utilize the mitochondrial respiratory chain for respiration. These cells are capable of differentiating into insulin-producing beta cells and pancreatic islet cells, which can be used in the treatment of diabetes.</p>

<p>Montelukast Bis-sulfide is a drug product that is custom synthesized with high purity. It has been studied for its metabolism, analytical properties, and natural sources. The metabolite of montelukast bis-sulfide has been extensively researched for pharmacopoeia as well as for drug development. Montelukast bis-sulfide is a synthetic compound that is not found in nature, but it has niche applications in research and development. CAS No.: 1242260-05-4</p>

<p>Miproxifene is a potent anticancer drug that has been shown to induce apoptosis and inhibit cell cycle progression in human cancer cells. This drug has been extensively studied in Chinese hamster ovary (CHO) cells and has demonstrated significant activity against various types of cancer, including leukemia. Miproxifene acts as a protein inhibitor and has been found to be effective against several tumor cell lines. It is a promising medicinal compound for the treatment of cancer, with potential applications in both chemotherapy and radiation therapy. Miproxifene is excreted primarily through urine and is well-tolerated by patients. Its use as an anticancer agent holds great promise for the future of cancer treatment.</p>

<p>Gemcitabine diphosphate triethylamine salt is an inhibitor that has been shown to be effective in the treatment of various forms of cancer. It works by inhibiting the activity of kinases, which are enzymes involved in the regulation of cell growth and division. Gemcitabine diphosphate triethylamine salt is a prodrug that is converted to its active form, gemcitabine, in vivo. This drug has been shown to inhibit the uptake of xylose by cancer cells, leading to decreased protein synthesis and induction of apoptosis. In addition, it has been found to be effective against human and Chinese medicinal tumor cells. Gemcitabine diphosphate triethylamine salt is a promising treatment option for patients with cancer who have not responded well to traditional chemotherapy or radiation therapy.</p>

<p>N-Methyl-4-phenylpiperidine is a synthetic drug that acts as a stimulant. It is a structural analog of the neurotransmitter acetylcholine and has been shown to have similar effects in knockout mice. N-Methyl-4-phenylpiperidine is metabolized by hydrolysis of the amide group, leading to the formation of alphaprodine and hydroxyphenylacetic acid. This drug has been shown to inhibit dopamine and serotonin uptake in rats, which may be related to its psychostimulant effects. Clinical pharmacology studies have shown that this drug can increase blood pressure, heart rate, and respiration rates in humans.</p>

<p>Piquindone is a medicinal compound that has shown promising anticancer properties in human tumor cells. It acts as an inhibitor of protein kinases, which are enzymes that regulate cell growth and division. Piquindone is an analog of a natural product found in Chinese urine and has been studied for its ability to induce apoptosis, or programmed cell death, in cancer cells. This compound has shown potent activity against various types of cancer cells and may have potential as a therapeutic agent for the treatment of cancer. Its mechanism of action involves the inhibition of specific kinases involved in cancer cell proliferation and survival. Piquindone is being investigated further for its potential as a cancer cell inhibitor.</p>

<p>Cycrimine hydrochloride is a molecule that is used as an anticholinergic drug. It has been shown to be effective in humans, with a half life of 3 hours and a duration of action of 8 hours. Cycrimin hydrochloride is also used as a diagnostic agent for irritant contact dermatitis and may be useful in the diagnosis of other allergic reactions. The molecule is also used as a diagnostic aid for cardiac arrhythmias.</p>

<p>DRI-c21045 is an analog of a medicinal compound that has been shown to inhibit the activity of a specific protein kinase involved in cell cycle regulation and tumor growth. This inhibitor has been demonstrated to induce apoptosis in cancer cells, making it a promising candidate for anticancer therapy. DRI-c21045 has been tested in both Chinese and human cancer cell lines and has shown potent activity against various types of tumors. Additionally, this compound has been detected in urine samples from patients with cancer, suggesting that it may have potential as a diagnostic marker for certain types of cancer. Overall, DRI-c21045 shows great promise as a potential anticancer agent with significant therapeutic potential.</p>

<p>Please enquire for more information about 2-(2-Chlorobenzoyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-vinyl-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Dodecenal is a human analog that has been studied for its potential anticancer properties. It has been shown to induce apoptosis, or programmed cell death, in tumor cells. This medicinal compound acts as an inhibitor of protein kinases, which play a crucial role in regulating the cell cycle and are often overactive in cancer cells. 3-Dodecenal has shown promising results in inhibiting cancer cell growth in Chinese hamster ovary cells and may have potential as a natural alternative to traditional cancer treatments. In addition, this compound has been detected in human urine and is believed to have potential health benefits beyond its anticancer properties.</p>

<p>Fonofos is a potent inhibitor that has been shown to induce apoptosis in Chinese hamster ovary cells. It is also known to inhibit chitin kinase, a protein that plays an important role in the biosynthesis of chitin, which is essential for the formation of cell walls in fungi and insects. Fonofos has medicinal properties and has been studied as a potential anticancer agent due to its ability to inhibit tumor growth. In vitro studies have shown that Fonofos can inhibit the growth of human cancer cells by inhibiting heparin-binding proteins. Additionally, it has been found to have inhibitory effects on several other enzymes involved in cancer development and progression. Although not approved for use in humans, Fonofos may hold promise as a therapeutic agent for the treatment of certain cancers.</p>

<p>Gentamicin Impurity</p>

<p>Please enquire for more information about Mycophenolate mofetil EP Impurity C including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Amiodarone impurity E is a nucleophilic compound that is synthesized by the acylation of a diazonium salt with an amine. It has been shown to be active against staphylococci, but not against subtilis. The reaction may be catalyzed by acid or chloride. Amiodarone impurity E is also demethylated and dehydrated to form the final product, amiodarone.</p>

<p>Amlodipine EP Impurity F maleate is an impurity of amlodipine, a drug product. It is a natural substance that has been classified as an API impurity in the United States Pharmacopeia (USP). The chemical name for this drug is 3-(2-chlorophenyl)-1-methyl-5-(o-tolyloxy)-2,4-dihydro-6H-[1,3]thiazolo[3,2-a]pyrimidin-7-one. Amlodipine EP Impurity F maleate has the following properties: C12H9ClNO2S and a melting point of 210°C with a purity of 99.5%. This compound was synthesized by custom synthesis and is used as an analytical standard for HPLC. This compound was also used during the development of amlodipine to determine its metabolism studies.</p>

<p>Sitagliptin monohydrochloride monohydrate is an inhibitor of dipeptidyl peptidase-4 (DPP-4), which is responsible for the degradation of incretin hormones. It is used in the treatment of type 2 diabetes mellitus, as it increases insulin secretion and reduces blood glucose levels. Recent studies have shown that Sitagliptin has anticancer properties, as it induces apoptosis in cancer cells. It also inhibits protein kinases, which are involved in tumor growth and metastasis. Capsaicin, a compound found in chili peppers, has been shown to enhance the anticancer activity of Sitagliptin in Chinese hamster ovary cells. The drug is excreted primarily through urine and has a low potential for drug interactions with other kinase inhibitors. Overall, Sitagliptin monohydrochloride monohydrate shows great promise as both a diabetes medication and an anticancer agent.</p>

<p>7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole (7'-MPB) is a benzimidazole derivative that is used as a medicine. It is made from recycled chemicals and has shown to have industrial applications as a catalyst for cyclization reactions. 7'-MPB is also used in the production of benzenesulfonic acid, which is an organic solvent. This chemical has been shown to be effective against high blood pressure, but has not been tested on humans yet. Telmisartan, which belongs to the angiotensin II receptor blocker class of drugs, can inhibit the synthesis of prostaglandins.</p>

<p>(-)-Sabinene is a natural compound found in urine and various medicinal plants, including Chinese herbs. It has been identified as an analog of another natural compound that exhibits potent anticancer activity. (-)-Sabinene has been shown to inhibit the activity of certain proteins involved in cell cycle regulation and apoptosis, which are important processes for the growth and survival of cancer cells. In addition, (-)-Sabinene has been found to have inhibitory effects on tumor kinase activity, making it a promising candidate for the development of new anticancer drugs. Studies have shown that (-)-Sabinene can effectively inhibit the growth of various types of cancer cells, making it a potential therapeutic agent for the treatment of cancer.</p>