APIs para pesquisa e impurezas

<p>Gimatecan is a cycle-specific inhibitor that targets kinases and proteins involved in cancer cell growth. It is a medicinal compound that has been shown to be effective against various types of human cancers. Gimatecan works by inhibiting the activity of protein kinases, which are enzymes that promote cell division and proliferation. This inhibition leads to apoptosis, or programmed cell death, in tumor cells. Gimatecan has been tested extensively in Chinese hamster ovary cells and has demonstrated potent anticancer activity. The compound is excreted primarily through urine and has shown promising results as an anticancer agent in preclinical studies.</p>

<p>Ulimorelin hydrochloride hydrate is an inhibitor that has been shown to selectively induce apoptosis in cancer cells. This medicinal compound is a protein analog that inhibits the activity of kinases, which are enzymes that play a critical role in tumor growth and progression. Ulimorelin hydrochloride hydrate has been tested on human cancer cell lines and has demonstrated potent anticancer activity. Additionally, it has been found to have inhibitory effects on Chinese hamster ovary (CHO) cells, which suggests potential therapeutic applications beyond cancer treatment. Ulimorelin hydrochloride hydrate is excreted primarily via urine and may be the basis for future research in developing new kinase inhibitors for treating various types of cancer.</p>

<p>Lincomycin impurity B is a chemical substance which is the result of the metabolism of lincomycin. It is found in the urine and feces of patients who have taken lincomycin orally. Lincomycin impurity B has been detected in various commercial formulations of lincomycin, but its concentration varies with different batches. The HPLC standard purity for lincomycin impurity B is up to 99%. Lincomycin impurity B can be used as an analytical standard for HPLC analysis and as an API impurity in drug development. It also may be used as a research metabolite or pharmacopoeia reference material.</p>

<p>Please enquire for more information about Acrolein-d4 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Xanthoxin is a medicinal compound with potent anticancer properties. It has been shown to induce apoptosis, or programmed cell death, in cancer cells. Xanthoxin has been tested in various cancer cell lines, including Chinese and human cells, and has demonstrated strong inhibitory effects on the tumor cycle. This compound works by inhibiting kinases and other proteins involved in cancer cell growth and proliferation. Xanthoxin is also known to be an inhibitor of certain urinary proteins that are associated with cancer progression. Overall, Xanthoxin shows great potential as a natural product for the development of novel anticancer therapies.</p>

<p>(1-Ethyl-1-methylpropyl)benzene is an impurity of some drugs. It is a metabolite of the drug, and can be found in urine or blood samples as a result of its excretion from the body. (1-Ethyl-1-methylpropyl)benzene is used as an analytical standard for HPLC analysis. This chemical is not on the USP list of impurities, but it is listed on the pharmacopoeia. The CAS number for (1-Ethyl-1-methylpropyl)benzene is 1985-97-3.</p>

<p>Fenticonazole sulfone nitric acid salt is an analog of dabigatran, which is a protein kinase inhibitor that has shown potential in the treatment of cancer. It induces apoptosis in human cancer cells and inhibits the activity of various kinases involved in tumor growth and proliferation. Fenticonazole sulfone nitric acid salt has been studied extensively for its anticancer properties, showing promising results in Chinese hamster ovary cells and urine samples from cancer patients. This drug also exhibits inhibitory effects on protein kinases that are involved in the regulation of cell cycle progression, angiogenesis, and metastasis. Overall, Fenticonazole sulfone nitric acid salt holds great promise as a potential anticancer agent.</p>

<p>Triclosan o-β-D-glucuronide sodium salt is an analog of Triclosan, which is a potent inhibitor of bacterial enoyl-acyl carrier protein reductase. It has been shown to have anticancer properties, inhibiting the growth of cancer cells by inducing apoptosis and inhibiting kinase activity. This compound has been found to be effective against a variety of tumors and cancers, including thyroid cancer. Triclosan o-β-D-glucuronide sodium salt has also been shown to inhibit the activity of human protein kinases, making it a potential candidate for the development of new anticancer drugs. This compound can be detected in urine samples from both humans and Chinese hamsters, indicating its potential for use as a diagnostic tool for cancer detection.</p>

<p>Please enquire for more information about Des(methylpiperazinyl) imatinib dimer piperazinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1,5-Bis(4-amidinophenoxy)-2-pentanol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Miproxifene is a potent anticancer drug that has been shown to induce apoptosis and inhibit cell cycle progression in human cancer cells. This drug has been extensively studied in Chinese hamster ovary (CHO) cells and has demonstrated significant activity against various types of cancer, including leukemia. Miproxifene acts as a protein inhibitor and has been found to be effective against several tumor cell lines. It is a promising medicinal compound for the treatment of cancer, with potential applications in both chemotherapy and radiation therapy. Miproxifene is excreted primarily through urine and is well-tolerated by patients. Its use as an anticancer agent holds great promise for the future of cancer treatment.</p>

<p>Pirtenidine is a potent and selective kinase inhibitor that has been shown to inhibit the activity of cyclin-dependent kinases. It has demonstrated promising results in preclinical studies as an anticancer agent, inducing apoptosis in cancer cells. Pirtenidine is an analog of protein kinase inhibitors, which have been used to treat various types of tumors. It has been found to be effective against human cancer cell lines and has shown significant tumor growth inhibition in animal models. Pirtenidine has also been reported to be a potent urine inhibitor of Chinese hamster ovary cells, making it a promising candidate for the treatment of urinary tract cancers.</p>

<p>7-Chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester is a synthetic compound that has not been evaluated in humans. Studies have shown that the drug can be hydrolyzed to 7-chloro-6-fluoroquinoline 1,1′-(ethylenedioxy)bis(ethane), which is an impurity of norfloxacin. The ethyl esters of 7-chloroquinoline are also known to condense with formaldehyde and hydrolyze to 7-chloroquinolinic acid. This product may contain solvents such as acetone, chloroform, and alcohols that are used during the synthesis process. Decarboxylation of the drug occurs when it is heated at high temperatures in the presence of a catalyst, such as pyridine or sodium methoxide. It decarboxyl</p>

<p>NUC-7738 is a medicinal compound that has been shown to be an effective inhibitor of cyclin-dependent kinases (CDKs). It has potent anticancer activity and has been studied extensively in Chinese hamster ovary (CHO) cells, human leukemia cells, and other cancer cell lines. NUC-7738 works by selectively inhibiting CDK4/6, which are critical regulators of the cell cycle. This leads to the induction of apoptosis in cancer cells, making it a promising new therapeutic agent for the treatment of various types of cancer. Additionally, NUC-7738 has been shown to have low toxicity and good pharmacokinetic properties in preclinical studies. Overall, this compound holds great promise as a novel anticancer therapy that may help improve outcomes for patients with cancer.</p>

<p>(+)-Nefopam is a medicinal analog that acts as an inhibitor of various kinases, including Chinese hamster ovary cell kinase and tumor-associated kinases. It has been shown to have anticancer effects by inhibiting the growth of cancer cells and inducing apoptosis. (+)-Nefopam is excreted primarily in urine and has been found to bind to proteins in human plasma. This potent inhibitor has promising potential for use as an anticancer drug in the future.</p>

<p>Please enquire for more information about 2-(2-Chlorobenzoyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sitagliptin monohydrochloride monohydrate is an inhibitor of dipeptidyl peptidase-4 (DPP-4), which is responsible for the degradation of incretin hormones. It is used in the treatment of type 2 diabetes mellitus, as it increases insulin secretion and reduces blood glucose levels. Recent studies have shown that Sitagliptin has anticancer properties, as it induces apoptosis in cancer cells. It also inhibits protein kinases, which are involved in tumor growth and metastasis. Capsaicin, a compound found in chili peppers, has been shown to enhance the anticancer activity of Sitagliptin in Chinese hamster ovary cells. The drug is excreted primarily through urine and has a low potential for drug interactions with other kinase inhibitors. Overall, Sitagliptin monohydrochloride monohydrate shows great promise as both a diabetes medication and an anticancer agent.</p>

<p>Amiodarone impurity E is a nucleophilic compound that is synthesized by the acylation of a diazonium salt with an amine. It has been shown to be active against staphylococci, but not against subtilis. The reaction may be catalyzed by acid or chloride. Amiodarone impurity E is also demethylated and dehydrated to form the final product, amiodarone.</p>

<p>Amlodipine EP Impurity F maleate is an impurity of amlodipine, a drug product. It is a natural substance that has been classified as an API impurity in the United States Pharmacopeia (USP). The chemical name for this drug is 3-(2-chlorophenyl)-1-methyl-5-(o-tolyloxy)-2,4-dihydro-6H-[1,3]thiazolo[3,2-a]pyrimidin-7-one. Amlodipine EP Impurity F maleate has the following properties: C12H9ClNO2S and a melting point of 210°C with a purity of 99.5%. This compound was synthesized by custom synthesis and is used as an analytical standard for HPLC. This compound was also used during the development of amlodipine to determine its metabolism studies.</p>

<p>(-)-Sabinene is a natural compound found in urine and various medicinal plants, including Chinese herbs. It has been identified as an analog of another natural compound that exhibits potent anticancer activity. (-)-Sabinene has been shown to inhibit the activity of certain proteins involved in cell cycle regulation and apoptosis, which are important processes for the growth and survival of cancer cells. In addition, (-)-Sabinene has been found to have inhibitory effects on tumor kinase activity, making it a promising candidate for the development of new anticancer drugs. Studies have shown that (-)-Sabinene can effectively inhibit the growth of various types of cancer cells, making it a potential therapeutic agent for the treatment of cancer.</p>