APIs para pesquisa e impurezas

<p>2,3',4',5-Tetrachlorobiphenyl is an analog with potent anticancer activity. It has been shown to induce apoptosis in human cancer cells and inhibit tumor growth in Chinese hamsters. This compound is also a potent inhibitor of protein kinases, including those involved in the regulation of cell growth and differentiation. Additionally, it has been found to enhance the activity of other kinase inhibitors such as tolvaptan. 2,3',4',5-Tetrachlorobiphenyl may be useful for developing new therapies for cancer treatment.</p>

<p>Please enquire for more information about 1-Chloro-3,5,7-trimethyladamantane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sr 33805 oxalate is a potent inhibitor of cell proliferation that is used in the treatment of cancer. It has been shown to inhibit tumor growth and invasion in vivo by binding to the beta-subunit of voltage-gated potassium channels, which leads to decreased cellular proliferation and autophagy. Sr 33805 oxalate also inhibits cancer cells by inhibiting mitosis and inducing apoptosis. This agent has cytotoxic effects on brain cells, with an IC50 value of 0.1 μM in vitro against rat cerebellar neurons. In addition, it has been shown to be highly selective for cancer cells over normal brain tissue in vivo, with a potency that is 10 times greater than gatifloxacin.</p>

<p>R401553 is a potent protein kinase inhibitor that has been shown to induce apoptosis and arrest the cell cycle in various human cancer cell lines. It belongs to the class of indole derivatives and has been found to be particularly effective against leukemia and tumor cells. R401553 selectively inhibits kinases that are involved in cell proliferation, survival, and angiogenesis. This inhibitor has been tested on Chinese hamster ovary (CHO) cells and human cancer cell lines, showing promising results in inhibiting tumor growth. R401553 may have potential as a therapeutic agent for the treatment of various cancers.</p>

<p>Please enquire for more information about 1-[2,3,4-Tris(methoxymethoxy)phenyl]-ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide is a high purity drug product. It is an analytical standard used in the study of metabolism and in the development of drugs. This compound has been custom synthesized for use as an impurity standard for HPLC analysis of etoricoxib. 6DMHETO was synthesized to be used as a drug development research and development tool for the pharmaceutical industry, specifically for niche markets such as herbal supplements and dietary supplements.</p>

<p>Please enquire for more information about 17-Acetoxy-6-chloro-3-ethoxypregna-3,5-dien-20-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Carboxy-3-ethoxy)phenyl acetic acid (CPAE) is a fluorescent compound that has been shown to have antidiabetic and luminescence properties. It absorbs light at wavelengths of 340, 405, and 455 nm and emits light at 525 nm. It also absorbs UV light at 310 nm and emits fluorescence at 495 nm. CPAE is formed by the condensation of two molecules of 4-carboxybenzaldehyde with one molecule of ethyl 3-ethoxypropanoate in the presence of a base. The crystals are monoclinic, with space group P2/c and lattice constants a = 12.872(1) Å, b = 7.319(1) Å, c = 17.814(2) Å, β = 98.664(9)°, Z = 2. The molecular weight is 182.24 g/mol and its molecular</p>

<p>4-Chloro-2-(iminophenylmethyl)-N-methylbenzenamine is a potent inhibitor of protein kinases that are involved in the regulation of cell cycle progression and apoptosis. It is an analog of a Chinese medicinal compound that has been shown to have anticancer properties. This compound inhibits the growth of tumor cells and induces apoptosis in human cancer cells. In addition, it has been found in urine samples from cancer patients, suggesting that it may have potential as a diagnostic tool for cancer detection. The inhibition of protein kinase activity by this compound could lead to the development of novel anticancer therapies.</p>

<p>Perindopril-N-desethylpentanoate is a drug product that is used in research and development of new drugs. It belongs to the class of drugs called angiotensin converting enzyme inhibitors, which act by inhibiting the conversion of angiotensin I to angiotensin II. Perindopril-N-desethylpentanoate can be used for the manufacture of HPLC standards. It can also be used as an analytical standard for impurities found in API, and has been shown to have niche applications in metabolism studies. This compound is purified to high purity levels that meet pharmacopoeia requirements.</p>

<p>Fluocortolone Impurity 13 is a metabolite of fluorocortolone. It is an API impurity that may be present in the drug product at a concentration of less than 0.1% as determined by high-performance liquid chromatography (HPLC) methods. Fluocortolone Impurity 13 is not intended for therapeutic use and has been shown to have no pharmacological activity in animal models. Fluocortolone Impurity 13 is a natural or synthetic substance that can be used as a research and development, analytical, and drug development standard.</p>

<p>Scopolamine is a muscarinic antagonist that is used to prevent motion sickness and the nausea and vomiting associated with anesthesia. It is an ester of scopolamine with hydrobromic acid. Scopolamine hydrobromide has been shown to have similar effects on humans as it does on rats. It is absorbed through the skin and metabolized in the liver, where it is excreted in bile and eliminated through the urinary system. The elimination half-life of scopolamine hydrobromide in humans ranges from 1 to 3 hours, which means that its effects wear off after about three hours.</p>

<p>Tametraline is a medicinal compound that has been used in Chinese traditional medicine to treat tumors. It is an analog of protein kinase inhibitors and has shown potent anticancer activity in preclinical studies. Tametraline is an inhibitor of kinases, which are enzymes involved in the regulation of cell growth and division. It induces apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of these enzymes. Tametraline has also been found to be excreted in urine, indicating that it can be effectively metabolized by the human body. This compound holds great promise as a potential treatment for various types of cancer.</p>

<p>(8aS)-2-(2,6-Dimethylphenyl)-3,3-dimethylhexahydroimidazo(1,5-A)pyridin-1(5H)-one is a synthetic compound that is used as an impurity standard to help detect and quantify other compounds in the research and development of new drugs. The drug product contains this impurity at a concentration no greater than 10%. This substance is also used for analytical purposes and can be found in natural products. Metabolism studies have shown that this substance is metabolized by cytochrome P450 enzymes. (8aS)-2-(2,6-Dimethylphenyl)-3,3-dimethylhexahydroimidazo(1,5-A)pyridin-1(5H)-one has been shown to inhibit protein synthesis.</p>

<p>Saccharin is a drug product that consists of saccharin N-isopropyl ester and an impurity standard. Saccharin is a synthetic sweetener that is found in the leaves of the herbaceous perennial S. dulcis, which has been used as a natural sweetener for centuries. Saccharin can be metabolized by humans to form 2-acetic acid and 4-methyl-1,2,3-thiadiazole (MTT) as a byproduct. The metabolite MTT may cause cancer in animals, but this has not been confirmed in humans. The pharmacopoeia specifies the purity of saccharin as 98% or greater. Metabolite standards are also provided for research purposes.</p>

<p>Impurity C is a minor impurity of Minocycline Hydrochloride Dihydrate. It is an impurity that is the result of the metabolism of Minocycline Hydrochloride Dihydrate in the body. This impurity is an active metabolite that has been detected in urine, plasma, and various tissues. Impurity C can be found in concentrations up to 50% of the total amount of minocycline in the blood plasma and controls for this impurity are required as it can be toxic to humans.</p>

<p>Tetrahydro-2-[2-(4-hydroxyphenyl)-1-methylethyl]-4,6,8-isoquinolinetriol is a synthetic compound that is used as an analytical reference standard for the detection of impurities in drugs. It is also commonly used as an impurity standard when synthesizing drugs and has been shown to be metabolized through various pathways including oxidation by cytochrome P450 enzymes. Tetrahydro-2-[2-(4-hydroxyphenyl)-1-methylethyl]-4,6,8-isoquinolinetriol is also used in drug development research and development.</p>

<p>Desmethylmaprotiline hydrochloride is a drug product that is used in the manufacture of other drugs. It is an impurity standard for analytical purposes and an API impurity for pharmacopoeia. Desmethylmaprotiline hydrochloride is also a metabolite of maprotiline, which is used in the treatment of depression. The chemical structure of Desmethylmaprotiline hydrochloride can be found under CAS No. 92202-51-2 and it has been shown to be synthesized from maprotiline.</p>

<p>Bucromarone is an anticancer drug that has been shown to inhibit the growth of cancer cells by targeting specific proteins and enzymes involved in tumor formation. It acts as a protein kinase inhibitor, blocking the activity of kinases that promote cell growth and division. Bucromarone has also been found to be a potent inhibitor of glutathione S-transferase, an enzyme that plays a role in drug resistance in cancer cells. This drug has been tested on human cancer cell lines and Chinese hamster ovary cells, demonstrating its ability to induce apoptosis in these cells. Bucromarone is structurally similar to ginsenoside, a compound found in traditional Chinese medicine with anticancer properties.</p>

<p>Please enquire for more information about N-[2-Aminoethyl) lenalidomide trifluoroacetic acid salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methiotepa is a potent anticancer drug that has been used for the treatment of various types of tumors. It is a Chinese hamster ovary (CHO) cell-derived analog of chitin, which inhibits the activity of protein kinase C. Methiotepa induces apoptosis in cancer cells by inhibiting DNA synthesis and repair, leading to cell death. This drug has also been shown to be a potent inhibitor of heparin-induced platelet aggregation in human blood. Methiotepa has been found to be effective against a wide range of cancers, including breast, lung, ovarian, and bladder cancer, among others. Its use as an anticancer agent may be due to its ability to inhibit the activity of various kinases and other enzymes involved in cancer cell proliferation and survival.</p>

<p>Bis(o-ethylbenzylamine) catechol dihydrochloride is a potent inhibitor of protein kinases that play a crucial role in the regulation of the cell cycle. It has been shown to induce apoptosis in various human cancer cell lines, including leukemia and Chinese hamster ovary cells. This compound inhibits the activity of several kinases, including indoleamine 2,3-dioxygenase (IDO), which is involved in tumor immune evasion. Bis(o-ethylbenzylamine) catechol dihydrochloride also acts as an inhibitor of other key proteins involved in the growth and proliferation of cancer cells. Its unique mode of action makes it a promising candidate for the development of novel anticancer therapies.</p>

<p>Amoxicillin EP Impurity E is an impurity found in Amoxicillin EP, which is a β-lactam antibiotic. It belongs to the group of β-lactam antibiotics and has antibacterial activity. Amoxicillin EP Impurity E is found by applying validation methods to measure the concentration of this product. The analytical method used for this impurity is a wavelength measurement or a magnetic field measurement. This impurity can be determined using chromatographic or elution methods. The chromatographic methods used are high performance liquid chromatography (HPLC) and gas chromatography (GC). Method development is required for determining the level of this impurity, as well as validation procedures for measuring it with various methods.</p>

<p>BGC-20-1531 is a medicinal compound that has been found to be an effective inhibitor of kinases in cancer cells. This Chinese-derived analog has shown potent anticancer activity in human tumor models and induces apoptosis in cancer cells. It works by inhibiting the protein kinase activity that is essential for cancer cell survival, leading to cell death. BGC-20-1531 has been shown to be effective against a wide range of cancer types and can be used as a potential therapeutic agent for cancer treatment. Additionally, this compound has been found in human urine and may have potential as a biomarker for cancer diagnosis and prognosis. With its unique characteristics, BGC-20-1531 is an exciting new prospect for the development of novel anticancer drugs.</p>

<p>Pentalenolactone O is a natural product, which is used as an analytical standard for the determination of metabolites in drug development and research. It can be synthesized from pentalenolactone A by hydrogenation with Raney nickel catalyst. Pentalenolactone O is also a synthetic compound that has been developed as an impurity standard for HPLC analysis. The purity of this compound is high, and it complies with the requirements of pharmacopoeias such as USP and BP.</p>

<p>Rivaroxaban is an analog of the kinase inhibitor which has been shown to have potent anticancer activity. It works by inhibiting kinases that are involved in cancer cell growth and survival. Rivaroxaban induces apoptosis in human and Chinese hamster ovary cells, leading to tumor cell death. This drug also inhibits glutathione S-transferase activity, which plays a role in the detoxification of reactive oxygen species and other electrophilic compounds. Rivaroxaban has been found to be effective against a variety of cancer types, including breast, lung, prostate, and colon cancers. It is a promising candidate for use as an anticancer therapy due to its ability to inhibit protein kinases that are overexpressed in cancer cells.</p>

<p>D-Ribose-L-cysteine is a combination of D-ribose and L-cysteine. It is used for the treatment of bowel disease, radiation injury, pentobarbital sodium induced ileus, atherosclerotic lesion, oral hypoglycaemic, neuronal death, psychotic disorder in AIDS patients and active antiretroviral therapy. D-Ribose-L-cysteine has been shown to decrease ATP levels and increase histological damage in v79 cells. D-Ribose-L-cysteine has also been shown to have a protective effect on hamster V79 cells against inflammatory bowel disease by decreasing the release of inflammatory cytokines.</p>

<p>2,6-Diethyl-4-thioisonicotinamide is a metabolite of 2,6-diethyl-4-(methylsulfonyl)pyrimidine and is used as an analytical standard for HPLC. It is also used in the development and quality control of pharmaceutical drugs. 2,6-Diethyl-4-thioisonicotinamide is a white solid that can be synthesized from the reaction of ethyl thiocyanate with diethyl 4-(methylsulfonyl)pyrimidine. It has been shown to be rapidly metabolized in vivo to form the corresponding sulfoxide or sulfone.</p>

<p>Miproxifene is a potent anticancer drug that has been shown to induce apoptosis and inhibit cell cycle progression in human cancer cells. This drug has been extensively studied in Chinese hamster ovary (CHO) cells and has demonstrated significant activity against various types of cancer, including leukemia. Miproxifene acts as a protein inhibitor and has been found to be effective against several tumor cell lines. It is a promising medicinal compound for the treatment of cancer, with potential applications in both chemotherapy and radiation therapy. Miproxifene is excreted primarily through urine and is well-tolerated by patients. Its use as an anticancer agent holds great promise for the future of cancer treatment.</p>

<p>1-(9-Deazaguanin-9-yl)-1,4-dideoxy-1,4-iminoribitol is an analog of mannitol that acts as a potent inhibitor of kinase activity. It has been shown to induce apoptosis in cancer cells and has potential as an anticancer agent. This compound inhibits the activity of Chinese hamster ovary cell kinases and luciferase kinases, which are involved in protein synthesis and tumor growth. Additionally, this compound has been found in human urine samples, suggesting that it may have clinical relevance as a therapeutic agent for cancer treatment. Overall, 1-(9-Deazaguanin-9-yl)-1,4-dideoxy-1,4-iminoribitol shows great promise as a novel inhibitor with potential for use in cancer therapy.</p>

<p>Granisetron is a drug that belongs to the group of serotonin receptor antagonists. It is used as an antiemetic, mainly in the prevention and treatment of nausea and vomiting caused by cancer chemotherapy and surgery. This drug has been shown to be effective in controlling nausea and vomiting, even when given after chemotherapy or surgical procedures. Granisetron hydrochloride was synthesized in 1988 by chemists at Hoffmann-La Roche. The synthesis was patented in 1990. Potential impurities are not listed on the USP or EP pharmacopeia, but these impurities have been detected during synthesis.</p>

<p>Please enquire for more information about 6,7-Dihydro canrenone lactol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (E)-4-(2,6-Dimethoxystyryl)-3-methoxyphenol-d6 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Amoxicillin EP Impurity L is an impurity standard for amoxicillin. It is a synthetic compound that is used to ensure the quality of amoxicillin drug products. Amoxicillin EP Impurity L has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. This impurity has also been shown to have anti-inflammatory properties and may be due to its inhibition of prostaglandin synthesis.</p>

<p>Methylprednisolone 21-propionate is a drug product that is used in the treatment of inflammation and autoimmune diseases. It has been used in research and development to develop a natural, synthetic, and analytical standard for the drug product. Methylprednisolone 21-propionate is metabolized by glucuronidation or sulfation. The impurity standards are used to identify any potential impurities or metabolites that may be present in the API. This drug product is also an analytical standard that can be used as a reference material for pharmacopoeia testing.</p>

<p>Linagliptin impurity E is a metabolite of the drug Linagliptin. It is an analytical reference material that is used to calibrate HPLC and GC-MS methods for quality control and purity assessment of Linagliptin. This impurity standard is also used for metabolism studies.</p>

<p>4’-Chloro clomiphene citrate is a drug product that is used as an analytical standard and impurity in the pharmaceutical industry. This compound is a natural metabolite of clomiphene, and is found in urine, serum, liver, and brain tissue. 4’-Chloro clomiphene citrate has been shown to have anti-inflammatory properties.</p>

<p>Glycerol 1-(26-hydroxyhexacosanoate) is a metabolite of the plant sterol, beta-sitosterol. It is a potent antimalarial agent and has been shown to be effective against plasmodium falciparum and plasmodium vivax. Glycerol 1-(26-hydroxyhexacosanoate) inhibits the growth of the malaria parasite by inhibiting enzymes that are required for its survival. The enzyme hydrolysis of glycerol 1-(26-hydroxyhexacosanoate) by cytochrome P450 2B6 produces 26-hydroxycholesterol and 26-hydroxydihydrocorticosterone, which have been shown to have antiplasmodial activity as well.</p>

<p>The Z-isomer impurity of pitavastatin is a synthetic compound that has been used as an analytical standard and pharmacopoeia reference. The Z-isomer impurity is not found in nature, but is generated by the hydrogenation of the natural product. It has been shown to be metabolized by CYP3A4 and CYP2C9 enzymes, which are the primary enzymes responsible for drug metabolism. This impurity does not have any therapeutic effect on the body, but can be used as a research and development standard for HPLC.</p>

<p>N-Desalkyl itraconazole is a triazole antifungal drug that belongs to the group of medicines. It is used in the treatment of systemic mycoses, including blastomycosis and histoplasmosis. N-Desalkyl itraconazole has been shown to inhibit the growth of fungi by interfering with their cell membranes and inhibiting their production of ergosterol. Calibration studies have shown that this drug binds to human liver microsomes and plasma proteins, as well as transporters such as P-glycoprotein. These interactions may influence its pharmacokinetics, which can be determined using a bioanalytical method.</p>

<p>Naringenin 4'-o-β-D-glucuronide sodium salt is an analog of naringenin, a flavonoid found in Chinese herbs and citrus fruits. It has been shown to possess potent anticancer activity by inhibiting cyclin-dependent kinases (CDKs) and inducing apoptosis in cancer cells. Naringenin 4'-o-β-D-glucuronide sodium salt acts as a protein kinase inhibitor that disrupts the signaling pathways involved in tumor growth and metastasis. This compound has been found to be effective against various types of cancer, including breast, lung, prostate, and colon cancer. It is excreted in human urine and can be used as a biomarker for evaluating the efficacy of cancer treatment. Overall, this sodium salt has great potential as an inhibitor of tumor cell proliferation and may be a promising therapeutic agent for cancer treatment.</p>

<p>Please enquire for more information about N-Acetyl-9-(acetylamino)-9-deoxyneuraminic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about VU 0465350 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Preterramide C is a drug that belongs to the class of drugs known as aminopyridines. It is a metabolite of preterramide A and has been used as an analytical reference standard for HPLC. This product is available in the form of a pure white crystalline powder with a purity greater than 98%. It has been shown to be an impurity in drug products and can be used as an impurity standard, as well as being synthesized by natural or synthetic means.</p>

<p>Citalopram N-oxide hydrochloride is the n-oxide form of the antidepressant drug citalopram. It is a metabolite of citalopram that has been shown to have higher activity than the parent compound. The presence of citalopram N-oxide was detected in plasma samples using liquid chromatography with a wavelength of 220 nm and diethylamine as an eluent. Citalopram N-oxide hydrochloride has been shown to be pharmacologically active in animal studies, but its effects are not well understood.</p>

<p>Cycrimine hydrochloride is a molecule that is used as an anticholinergic drug. It has been shown to be effective in humans, with a half life of 3 hours and a duration of action of 8 hours. Cycrimin hydrochloride is also used as a diagnostic agent for irritant contact dermatitis and may be useful in the diagnosis of other allergic reactions. The molecule is also used as a diagnostic aid for cardiac arrhythmias.</p>

<p>Please enquire for more information about Tofacitinib impurity 5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dihydro lafutidine is a drug product that is used in the treatment of acid-related disorders. It is an analytical standard and impurity control compound for HPLC. Dihydro lafutidine has been shown to inhibit the production of gastric acid by blocking the histamine H2 receptor, which is involved in regulating stomach pH. It also inhibits the growth of Helicobacter pylori, which may be due to its ability to bind to bacterial 16S ribosomal RNA and inhibit protein synthesis.</p>

<p>Please enquire for more information about 3-HABA kanamycin A sulfate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>BIM 23127 is a protein kinase inhibitor that acts as an analog of vitamin K. It has been shown to have anticancer effects by inducing apoptosis in cancer cells. BIM 23127 inhibits the activity of kinases, which are enzymes that regulate cell growth and division. This inhibition leads to a decrease in tumor growth and may be useful in the treatment of various types of cancer. BIM 23127 has been tested in Chinese hamster ovary cells and human urine, showing promising results as a potential anticancer agent. Its ability to specifically target cancer cells while sparing healthy cells makes it a desirable option for cancer treatment.</p>

<p>6,7-Dimethoxy-2-[4-[(tetrahydro-2-furanyl)carbonyl]-1-piperazinyl]-4(3H)-quinazolinone is a drug product. It is an analytical standard for the impurity of CAS No. 1177261-73-2. This compound has been synthesized by custom synthesis and its purity is high. The compound has been used in research and development of drugs, pharmacopoeia, HPLC standards, and other related fields.</p>

<p>Niguldipine hydrochloride is a novel prodrug of the calcium channel blocker, niguldipine. This drug is an ATP-binding cassette transporter substrate that inhibits bowel disease by binding to the transporter protein, thereby blocking its activity. The drug has been shown to have low potency and is not effective against infectious diseases. Niguldipine hydrochloride may act as an autophagy inducer, which may reduce the number of cancer cells in human osteosarcoma cells. It also has been shown to inhibit receptor activity in air entrainment models.</p>

<p>Please enquire for more information about (3S,4R)-3-Methyl-4-phenylpiperidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ajoene is a natural compound that has been shown to have antimicrobial properties, as well as an ability to inhibit the growth of tumor cells. Ajoene is also a potent inhibitor of dextran sulfate proteoglycan synthesis in vitro and has been shown to produce a hypoglycemic effect in vivo. Ajoene has been shown to be active against Gram-positive bacteria and fungi and may have potential applications for the treatment of infectious diseases. Further research is needed to determine whether ajoene may be used as an antioxidant or neuroprotective agent.</p>

<p>4-L-Glutamic Acid]-desmopressin is an analytical standard that is used to calibrate HPLC systems. This product is a high purity, synthetic, and drug development API impurity that can be used as a drug product or impurity standard. It is also available as an HPLC standard, niche, and custom synthesis. 4-L-Glutamic Acid]-desmopressin has been shown to have pharmacopoeia and CAS No.</p>

Tecloftalam imide is a drug product that is an analytical standard. It is a natural product, which can be obtained from the fermentation of Streptomyces sp. (CAS No. 26491-30-5). Tecloftalam imide is also an impurity in some APIs. It can be synthesized, and has been used as an impurity standard for HPLC, with a purity of >99%. Tecloftalam imide has been used in drug development and research and development. It has been shown to have niche applications in pharmacopoeia.

<p>5-Oxo atorvastatin is an impurity standard for atorvastatin. It is a synthetic metabolite that has been observed in the urine of patients receiving atorvastatin. 5-Oxo atorvastatin can be used as a reference compound to calibrate HPLC measurements and as an analytical standard in pharmacopoeia testing.</p>

<p>Amlodipine besilate impurity A is a low-energy impurity that is formed in the crystallization process. It is an amide compound that has a hydrogen bond with crotonic acid and amlodipine, and can be found in acidic environments. The structural formula for this impurity is C8H14NO2S·C4H6O4·CH3OH.</p>

<p>Please enquire for more information about (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-vinyl-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Descyclopropyl-2-oxopropyl prasugrel is a metabolite of the prodrug prasugrel. It is a synthetic compound that has been shown to have pharmacological activity similar to its parent drug. Descyclopropyl-2-oxopropyl prasugrel has a purity of &gt;98% and is available as an API standard in impurity grade and as custom synthesis. The chemical name for descyclopropyl-2-oxopropyl prasugrel is 2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2- yl)butoxy]-N-(3S)-(3aR*,8aS*)-octahydroindole-1,3(2H)-dione.</p>

<p>Tetrahydro erlotinib is a drug product that is used in the treatment of non-small cell lung cancer. Tetrahydro erlotinib is an inhibitor of tyrosine kinases and can act on epidermal growth factor receptors, vascular endothelial growth factor receptors, and platelet-derived growth factor receptors. It has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. Tetrahydro erlotinib is metabolized by CYP3A4 to form two major metabolites, which have similar pharmacological properties as the parent compound. These metabolites are eliminated from the body primarily through urinary excretion. Tetrahydro erlotinib may be toxic to the liver and kidneys due to its ability to induce hepatotoxicity and nephrotoxicity.</p>

<p>Alverine EP Impurity C is a by-product of the synthesis of alverine, which is an ammonium salt. The process involves the use of high yield, high purity triflic acid, and organic solvents. The reaction system is typically carried out in a solvent such as toluene or dichloromethane. The organic solvent is then removed by filtration and the desired product can be obtained by crystallization or recrystallization. Alverine EP Impurity C has been shown to have insecticidal properties when applied externally, due to its interaction with insect stereoisomers. It also has anticancer activity and may be used in cancer therapy treatments that involve decompressing tumours and increasing blood supply to the area. Alverine EP Impurity C also has a citric acid binding property that makes it insoluble in water.</p>

<p>14-Epiandrographolide is a natural product that can be found in the plant Andrographis paniculata. It has been shown to have anti-inflammatory, anticancer, and antibacterial properties. 14-Epiandrographolide inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Rifapentine also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

<p>2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran is a benzofuran. It is a yellow solid that can be dissolved in water and alcohol.</p>

<p>Fluocortolone Impurity 5 is a drug product that is custom synthesized for research and development purposes. It has high purity and analytical standards, as well as metabolite and impurity standards. Fluocortolone Impurity 5 can be used in pharmacopoeia, natural products research, drug development, and other niche applications. Fluocortolone Impurity 5 is a synthetic compound that is not found in nature.</p>

<p>6β-Phthalimidopenicillanic acid is an analog of penicillin that acts as an inhibitor of cyclin-dependent kinases (CDKs). It has been shown to have potent anticancer activity and induce apoptosis in tumor cells. This medicinal compound specifically targets CDKs, which are important regulators of the cell cycle and have been implicated in cancer development. 6β-Phthalimidopenicillanic acid has been tested in Chinese hamster ovary cells and human cancer cell lines, where it has demonstrated significant inhibition of CDK activity. This inhibitor also exhibits potential as a protein kinase inhibitor, making it a promising candidate for further development as an anticancer agent.</p>

<p>Abacavir is an antiviral drug that is used to treat HIV/AIDS. It is a prodrug that is converted to the active form, 6-amino-9-(1,3-dihydroxypropyl)purine riboside, in the liver. Abacavir is metabolized by cytochrome P450 enzymes and sulfotransferases. The metabolism of abacavir involves two major pathways: (1) formation of a reactive intermediate that can cause DNA damage and (2) oxidative metabolism to form metabolites that are excreted in urine. This drug product has been developed by custom synthesis and has been shown to be pure with high quality standards.</p>

<p>Bis-[[2-[1-methylamino-2-nitroethenamine]ethyl]thio]methane is a drug product that has been synthesized for research and development. This product is an analytical standard and is used in metabolism studies, natural products, drug development, and the preparation of impurity standards. The CAS number for this product is 1331637-48-9. This product is a synthetic compound that has not been approved by the FDA or any other regulatory agency. It can be shipped to US destinations only.</p>

<p>Ethyl 3-(3-amino-4-(2-((4-cyanophenyl)amino)-N-methylacetamido)-N-(pyridin-2-yl)benzamido)propanoate is an analytical standard and a drug development impurity in the preparation of HPLC standards. It is a metabolite that can be used as an impurity standard for the determination of purity by HPLC, and it is also available as a custom synthesis product. This compound has been assigned CAS No. 1648817-93-9.</p>

<p>9,10-Dihydro-9,10-ethanoanthracene-9-carboxylic acid (DECA) is a halogenated aliphatic carboxylic acid that can be used as an oxidizing agent. It is a diluent in the synthesis of other compounds and can also act as a catalyst for reactions involving carboxylic acids. DECA has been shown to selectively oxidize carboxylic acids with one or more carbon atoms in the aliphatic chain. This is often done with propionic acid, which is oxidized to acrylic acid. The selectivity of DECA for this reaction is attributed to its ability to react with the carbonyl group in the carbon chain due to its electron withdrawing properties.</p>

<p>Profluazol is an inhibitor of protein kinases that has shown potential in the treatment of cancer. This Chinese indole derivative has been found to inhibit the proliferation of leukemia cells and induce apoptosis in tumor cell lines. Profluazol specifically targets kinases involved in the regulation of cell cycle progression, such as cyclin-dependent kinase 2 (CDK2) and mitogen-activated protein kinase (MAPK), leading to a decrease in cancer cell growth. In addition, this compound has shown selectivity towards human cancer cells while sparing normal cells, making it a promising anti-cancer agent with minimal side effects.</p>

<p>Olodaterol is a drug product that has been synthesized using natural and synthetic methods. It is an API impurity that is present in the CAS No. 869478-13-7, which is a custom synthesis of olanzapine. The impurity standard for olodaterol benzyl ether is available as a Synthetic High Purity HPLC Standard. The purity of this product has been tested by HPLC and found to be &gt; 98%. Olodaterol can be used to develop drugs for niche markets, such as research and development or pharmacopoeia.</p>

<p>Quinovin is a Chinese medicinal compound that has been shown to have potent anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in the growth and proliferation of cancer cells. Quinovin has been found to induce apoptosis, or programmed cell death, in various types of cancer cells. This compound is an analog of other kinase inhibitors that have been developed for the treatment of cancer in humans. Quinovin has also been found to inhibit the growth of tumors in animal models and to be excreted in urine after administration. Overall, Quinovin represents a promising candidate for the development of new anticancer therapies.</p>

<p>4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol is a synthetic compound that is used in the development of pharmaceutical drugs. It is used as an analytical standard for HPLC and is available as a new drug product. 4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol has been shown to be metabolized by CYP 450 enzymes and to be an impurity in API production. 4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol is also found in natural products such as plant leaves and bark.</p>

<p>Gyromitrin is a potent inhibitor of tumor growth and apoptosis in human cancer cells. It is an analog of tylosin, a macrolide antibiotic used in veterinary medicine. Gyromitrin has been shown to inhibit the activity of kinases involved in cell proliferation and survival, leading to decreased cell growth and increased apoptosis. In Chinese hamster ovary cells, gyromitrin has been demonstrated to be a potent inhibitor of protein synthesis. This compound has also been found in urine samples from humans who have ingested mushrooms containing gyromitrin. Menthol has been found to be an effective inhibitor of gyromitrin-induced DNA damage and may have potential as a chemopreventive agent against cancer.</p>

<p>2-(Propylamino)-propiotoluidid-hydrochlorid is a drug product that is used as an analytical standard for the determination of impurities in pharmaceuticals. It is a synthetic, natural, and research and development metabolite with niche applications. This product has been shown to be pharmacologically active in metabolism studies on animals. CAS No. 35891-99-7</p>

<p>Please enquire for more information about Tyk2-in-5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Benz[A]anthracene-7-chloromethane-13C including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>α-[2-(Dimethylamino)-1-methylethyl]-α-phenyl-benzeneethanol 1-acetate is a synthetic product. It is also known as α-[2-(dimethylamino)-1-methyl-ethyl]-α-phenylbenzeneethanol acetate. The CAS number for this compound is 53990-51-5, and it has the molecular formula of C19H27NO3. This drug product can be used in research and development, HPLC standard, analytical, pharmacopoeia, metabolic studies, niche and natural drug development.</p>

<p>Please enquire for more information about Carbofuran N,N-dibutyl-2λ1-disulfan-1-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Taxol is a natural product that can be found in the bark of the Pacific yew tree. It has been shown to have synergistic effects with 5-HT2A receptor antagonists, such as gamma-aminobutyric acid (GABA) and 5-hydroxytryptamine (5-HT). Taxol has been used in the treatment of cancer, specifically breast cancer. In addition, it has been shown to have an effect on cardiac function by interfering with neurotransmission. This drug also blocks 5-HT2C receptors and is a human protein.</p>

<p>Sitagliptin is an oral dipeptidyl peptidase-4 inhibitor that is used to treat type 2 diabetes. It binds to the active site of the enzyme and reversibly blocks the action of the enzyme, thereby inhibiting the breakdown of a number of important hormones such as glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide. Sitagliptin hydroxy amide impurity is an impurity in sitagliptin that inhibits oxidoreductases, enzymes that catalyze oxidation reactions. The enantiomeric purity of sitagliptin hydroxy amide impurity is unknown.</p>

<p>Please enquire for more information about BET-IN-4 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PF-04856264 is an anticancer drug that belongs to the class of protein kinase inhibitors. It has been shown to inhibit the growth of cancer cells by inducing apoptosis, which is a process of programmed cell death. PF-04856264 is a medicinal analog of nalbuphine and has been tested in human urine for its effectiveness against various types of cancer. This drug specifically targets tumor cells and inhibits their growth by blocking the activity of certain kinases that are involved in cell division. PF-04856264 has also been found to be effective against Chinese hamster ovary cells, making it a promising candidate for further cancer research.</p>

<p>Please enquire for more information about Lolcde-in-1 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cyproterone acetate EP Impurity A is a metabolite of cyproterone acetate. Cyproterone acetate is an androgen receptor antagonist drug product which is used in the treatment of prostate cancer and male pattern hair loss. Cyproterone acetate EP Impurity A has been found to be toxic to rats when administered orally, with LD50 values of 40-120 mg/kg, depending on the study. It also has been shown to inhibit hepatic p450 enzymes in rats after oral administration.<br>Cyproterone acetate EP Impurity A is an impurity standard for cyproterone acetate and is available as a pure compound or as a custom synthesis. This impurity can be analyzed using HPLC with UV detection at 210 nm or by GC with flame ionization detection at 230°C. The purity of this compound can be confirmed using NMR spectroscopy, melting point determination, or elemental analysis.END&gt;</p>

<p>Amaroswerin is an analog of a medicinal plant compound that has been shown to have potent anticancer properties. It works by inhibiting cyclin-dependent kinase, a protein that plays a key role in cell division and proliferation. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Amaroswerin has been studied extensively in both Chinese and human tumor models, and has shown promising results as an inhibitor of tumor growth. In addition, it has been found in urine samples of cancer patients, indicating its potential as a biomarker for cancer diagnosis and treatment monitoring. Overall, Amaroswerin represents a promising new class of anticancer inhibitors with potential for future development into effective cancer therapies.</p>

<p>Please enquire for more information about 1,4-Dihydro-4-oxo-3-quinolinecarbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>b-1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine is a drug product that is used in the development of drugs. It is a metabolite of cyclizine and has been shown to have antihistaminic effects. This chemical compound is an impurity standard for HPLC analyses of other substances. b-1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine has also been shown to be a synthetic intermediate in the synthesis of pharmaceuticals.</p>

<p>3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol is a potent inhibitor of cancer cell growth and tumor development. It has been shown to induce apoptosis in human cancer cells by inhibiting kinase activity. This compound is an analog of quetiapine and has anticancer properties. 3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol also exhibits inhibitory effects on somatostatin receptors in Chinese hamster ovary cells. It has been found in urine samples and may have potential as a therapeutic agent for the treatment of cancer. The compound has shown promising results as a kinase inhibitor with potential applications in the development of novel anticancer drugs.</p>