Peptídeos

TIP39 is a peptide inhibitor that is a member of the TIP family. It inhibits the activity of calcineurin, a calcium-dependent phosphatase enzyme, and thereby prevents it from dephosphorylating nuclear factor of activated T cells cytoplasmic 1 (NFATc1), which regulates signaling pathways that control inflammatory responses. TIP39 has been shown to inhibit calcineurin in both human and bovine cell lines. This drug has been used as a research tool to study peptide-receptor interactions and ion channels.

IL 4R is a receptor for Interleukin-4. It is a member of the type II cytokine receptor family and has been shown to be an inhibitor of cell proliferation. IL 4R also interacts with the protein tyrosine phosphatase SHP2, which plays a role in signaling pathways. IL 4R binds to specific Ligands, such as IL-4 and IL-13, that are found in the extracellular matrix and on the surface of cells. These interactions activate the receptor and lead to intracellular signaling cascades. The protein's activation can be inhibited by small molecules like peptides or antibodies that bind to its extracellular domain.

Amino-dPEG®4-(m-dPEG®11)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®4-(m-dPEG®11)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

IL1-beta is a pro-inflammatory cytokine that belongs to the Interleukin family. It is expressed in response to inflammation, trauma, and infection and can be found in many tissues of the body. IL1-beta has been shown to have a wide variety of effects on the body including regulating cell growth and differentiation. IL1-beta has also been shown to bind with high affinity to specific receptors that are known as type I interleukins. These receptors are able to activate other cells such as T cells and macrophages, which produce more inflammatory cytokines such as tumor necrosis factor alpha (TNFα) and interferon gamma (IFNγ).
IL1-beta Mouse is a mouse monoclonal antibody that binds specifically with IL1-beta. This antibody can be used for immunohistochemistry or Western blotting experiments. It can also be used for blocking studies using an ELISA assay or RIA assay.

CIF1 is a protein that in humans is encoded by the CIF1 gene. It belongs to the family of ion channels and ligand-gated ion channels. The channel is activated by acetylcholine, a neurotransmitter, and mediates fast synaptic transmission at neuromuscular junctions. CIF1 has been shown to bind to the nicotinic acetylcholine receptor (nAChR) subunit alpha-4/beta-2. This binding leads to inhibition of nAChR function, which may be useful for treatments of conditions such as Parkinson's disease or Alzheimer's disease.

Methoxytrityl-S-dPEG®8 Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Methoxytrityl-S-dPEG®8 Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Please enquire for more information about Fmoc-Trp-Rink-Amide MBHA Resin including the price, delivery time and more detailed product information at the technical inquiry form on this page

G CSF Mouse is a recombinant protein that is an inhibitor of the G-CSF receptor. It has been shown to inhibit the activity of ion channels in cells. G CSF Mouse is a research tool that can be used to study the biology of proteins and peptides. This product can also be used for antibody production and as a reagent for cell biology and pharmacology experiments.

Human s-IgA (Saliva) ELISA (1ea) is a human IgA immunoglobulin that is found in saliva. It is used to detect the presence of antibodies against specific substances such as drugs, food, and other allergens.

Neuromedin U is a peptide that plays a role in the regulation of cardiovascular function and the modulation of pain. It has been found to activate receptors for calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP). Neuromedin U has also been found to be an inhibitor of ligand-induced activation of ion channels, such as those activated by bradykinin or histamine. This protein can be used as a research tool in cell biology, pharmacology, and biochemistry.

m-dPEG®12-Amido-dPEG®12-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®12-Amido-dPEG®12-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

AC 253 is an amylin (AMY3) receptor antagonist.

Joining peptide is a peptide that activates the receptor. It consists of two parts: a receptor-binding domain and a cell-penetrating domain. The receptor-binding domain is designed to bind to specific receptors on cells, while the cell-penetrating domain allows the peptide to cross the plasma membrane and penetrate into the cytoplasm. Joining peptide is used as an activator for ion channels and ligands for antibodies or receptors. Joining peptide can be used in research as a tool for investigating protein interactions, pharmacology, and cell biology.

TRAIL is a peptide that belongs to the group of cytokines. It activates the receptor-mediated apoptosis pathway in cells that have been stimulated by tumor necrosis factor-α (TNF-α) and other pro-inflammatory cytokines. TRAIL has also been shown to inhibit protein interactions, such as those between the TNF receptors and their ligands or receptors, like CD4. TRAIL also binds to the Fas receptor and its ligand, FasL, which leads to activation of caspases in a similar manner as FADD binding. The recombinant human TRAIL is a research tool for studying cell biology and pharmacology.

Anti Galanin (15-29) (Rat) Serum is a recombinant protein that is used as a research tool and has been shown to inhibit the activity of ion channels. It has been used to study the interactions between proteins, peptides, and receptors. This product has not been evaluated by the FDA for use in humans.

Salusin-beta is a peptide that is used as a research tool for the study of ion channels and protein interactions. Salusin-beta inhibits potassium currents in cells, which may be due to its ability to bind to receptor sites on the cell membrane. It also inhibits the activity of protein kinase C and calcium channels. Salusin-beta has been shown to be an inhibitor of protein interactions, such as those between α-synuclein and synaptotagmin, which are involved in Parkinson's disease.

Neuromedin B is a neuropeptide that is found in the central nervous system and peripheral tissues. It activates ligand-gated ion channels, including nicotinic acetylcholine receptors. Neuromedin B has been shown to inhibit the activity of voltage-gated potassium channels and calcium channels, which are involved in neurotransmission. It also inhibits the activation of phospholipase C, which is involved in cellular signaling pathways. This peptide can be used as a research tool for studying the pharmacology of peptides and as an antibody for immunohistochemistry studies.

TentaGel is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. The TentaGel S base resins are available with several different derivative choices. The typical capacity range for our TentaGel base resins is 0.2-0.3 meq/g.
Application: (90 µm)
Substitution Functional Group:-CH2-CH2-SH

Obestatin is a neuropeptide that was first isolated from the mouse and rat hypothalamus. The Obestatin (Mouse, Rat)-EIA Kit is an in-house ELISA assay for the detection of mouse and rat obestatin. This kit can be used to detect obestatin in serum, plasma, or cell culture supernatant samples. It is a useful tool for studying the role of this peptide in various biological processes.

The ALB, GIG20, GIG42 MS Calibrator (25nmol) is a Proteomics Tools product that has been designed to support the identification of biologically active peptides in proteomics. The ALB, GIG20, GIG42 MS Calibrator (25nmol) is a tryptic peptide derived from human serum albumin and can be used as a precursor for the identification of other tryptic peptides in proteomic samples. The New England Peptide Company offers this product at a competitive price and with high quality.

Mannose-binding lectin 2 (MBL2) is a protein that is encoded by the MBL2 gene. It is an activator of the lectin complement pathway, which plays an important role in innate immunity. MBL2 binds to mannose-rich oligosaccharides and activates the lectin complement pathway. This protein also interacts with ion channels, cell surface receptors and other proteins. The recombinant human MBL2 has been expressed in E. coli. The purified protein is supplied at >95% purity and has a CAS number of 80613-62-8.

The Green Fluorescent Protein Recombinant is a highly versatile product that offers a wide range of applications in the field of proteomics. This PEG-linked peptide is designed to enhance the stability and solubility of proteins, making it an ideal choice for various research purposes. With its unique PEG-protected structure, this recombinant protein ensures optimal performance and long-lasting results. Whether you're conducting protein-protein interaction studies or investigating protein localization, this PEGylated peptide will provide you with accurate and reliable data. Trust in the exceptional quality of this product to advance your research and unlock new insights in the world of proteomics.