Peptídeos
Subcategorias de "Peptídeos"
Foram encontrados 29874 produtos de "Peptídeos"
P2-Hp-1935
P2-Hp-1935 is an antimicrobial peptide isolated from the skin secretions of the Montevideo tree frog (Hypsiboas pulchellus). P2-Hp-1935 displays activity against Gram positive and negative bacteria.Peso molecular:1,935.32 g/molSARS-CoV-2 Nucleoprotein (86-100)
The coronavirus (CoV) nucleoprotein is the major component of CoV structural proteins. Also known as the nucleocapsid protein, it is an abundant RNA-binding protein critical for viral genome packaging. These factors make nucleoprotein a good target for developing new antiviral drugs. In addition, the identification of epitopes within the nucleoprotein sequence can help design more effective SARS-CoV-2 vaccines.Models have predicted epitopes exhibiting antigenicity, stability and interactions with MHC class-I and class-II molecules. Nucleoprotein (86-100) is an epitope candidate with various HLA restrictions. This epitope can be used to better vaccine design for more durable CD4+ and CD8+ T cell responses for long-lasting immunity.
Peso molecular:1,824 g/molfTAT
Peptide derived from the HIV transactivator of transcription protein. TAT is a cationic cell-penetrating peptide.
Peso molecular:1,396.66 g/molAD01 N-terminal Q
AD01 is a derivative of the FK506 binding protein-like (FKBPL), and exerts potent anti-angiogenic activity in vitro and in vivo to control tumour growth.Recent studies have shown that AD-01 inhibits Rac-1 activity, and up-regulates RhoA and the actin binding proteins, profilin and vinculin.In this way, the anti-angiogenic proteins, FKBPL, and AD-01, offer a promising and alternative approach for targeting both CD44 positive tumours and vasculature networks. Recent clinical studies have shown that AD01 and other FKBPL-based peptides may offer an alternative for targeting treatment-resistant breast cancer stem cells.Peso molecular:2,702.4 g/mol[5-FAM]-(KFF)3K
(KFF)3K is a cationic cell penetrating peptide which can be conjugated to PNA oligomers to aid in their penetration of the bacterial cell wall to function as anti-microbials. It contains 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag.Peso molecular:1,769.9 g/molSARS-CoV-2 NSP13 (231-245)
The SARS-CoV-2 non-structural protein 13 (NSP13) has been identified as a target for anti-viral therapeutics due to its highly conserved sequence and is essential for viral replication. NSP13 is part of the helicase superfamily 1B. As an NTPase and RNA helicase, NSP13 binds to RNA-dependent RNA polymerase and acts in concert with the replication-transcription complex to stimulate backtracking and further activate NSP13 helicase activity. These factors make NSP13 a good target for developing new antiviral drugs. In addition, the identification of epitopes within the NSP13 sequence can help design more effective SARS-CoV-2 vaccines.Models have predicted epitopes exhibiting antigenicity, stability and interactions with MHC class-I and class-II molecules. NSP13 (231-245) is an epitope candidate with various predicted HLA restrictions. This epitope can be used to better vaccine design for more durable CD4+ and CD8+ T cell responses for long-lasting immunity.
Peso molecular:1,618.8 g/molFormyl-MLF-[Cys(AF488)]
Formyl-MLF-[Cys(AF488)] is composed of the chemotactic peptide: N-formyl-methionine-leucine-phenylalanine. N-formyl-methionine is the N-terminal amino acid present on bacteria and allows the bacteria to interact with phagocytic cells such as macrophages and monocyte-derived dendritic cells through surface formyl-MLF receptors. As a result Formyl-MLF labelled with the fluorescent dye, Alexa Fluor 488 can be used as a marker of bacterial infections. It has also been demonstrated that the use of multiple formyl-MLF moieties can target polymeric drug delivery molecules to phagocytic cells. In addition to Alexa Fluor 488's application in marking bacterial infections, its properties of being photo-bleaching resistant and having a high quantum yield allow it to carry out its most common use in the visualisation and location of dendritic structures and synapses.Peso molecular:1,237.3 g/molSARS-CoV-2 NSP7 (46-60)
SARS-CoV-2 NSP7 is part of the RNA-dependent RNA polymerase heterotetramer for mediating coronavirus RNA synthesis. NSP7 and NSP8 form a channel to confer processivity on RNA polymerase. NSP7 aids in stabilising NSP12 regions involved in RNA binding and is essential for a highly active NSP12 polymerase complex. These factors make NSP7 a good target for developing new antiviral drugs. In addition, the identification of epitopes within the NSP7 sequence can help design more effective SARS-CoV-2 vaccines.Models have predicted epitopes exhibiting antigenicity, stability and interactions with MHC class-I and class-II molecules. NSP7 (46-60) is an epitope candidate with various HLA restrictions. This epitope can be used to better vaccine design for more durable CD4+ and CD8+ T cell responses for long-lasting immunity.Peso molecular:1,678.9 g/molLL-37 fragment (30-34)
LL-37 is a member of the large cationic family of anti-microbial peptides called cathelicidins which have broad-spectrum anti-microbial activity and are expressed in many species. The only cathelicidin found in humans is LL-37, this is produced in epithelial cells, by proteolytic cleavage from the C-terminal of the hCAP-18 protein. LL-37 can be processed into different forms of anti-microbial peptides. As well as its anti-microbial properties LL-37 also regulates many aspects of the innate immune system and overexpression of LL-37 has been linked to autoimmune diseases such as asthma and psoriasis, making LL-37 the most studied form of the human cathelicidin peptides.More recently, studies have shown that LL-37 binds to SARS-CoV-2 S protein and inhibits binding to its receptor hACE2, which may inhibit viral entry into the cell. LL-37 is upregulated by vitamin D, therefore this may be one mode of action for the positive outcomes seen with vitamin D treatment for Covid-19.Cor e Forma:PowderPeso molecular:597.4 g/molOvalbumin (324-338), chicken, quail
Ovalbumin (OVA) is the primary protein in egg-white, and is involved in initiating food allergies and asthma. It is a highly immunogenic protein and can be used for peptide conjugation in the development of antibodies.OVA (324-338) is a class I (Kb)-restricted peptide epitope of OVA. The ovalbumin fragment is presented by the class I MHC molecule, H-2Kb.
Peso molecular:1,559.8 g/molFz7-21
Binds to the cysteine rich domain of the Frizzled 7 receptor and inhibits Wnt signalling in cultured cells and stem cell function in intestinal organoids.
Cor e Forma:PowderPeso molecular:1,794.8 g/molDYKDDDDK FLAG peptide
Highly specific protein tag that can be added to a protein using recombinant DNA technology. FLAG is an artificial antigen to which high affinity monoclonal antibodies have been raised, therefore allowing for highly effective protein purification by affinity chromatography as well as accurate localisation of FLAG tagged proteins within living cells, or Western blots. FLAG peptide can be used to effectively purify complexes with multiple proteins as its mild purification procedure tends not to disrupt such complexes. It can be used to obtain proteins of sufficient purity for x-ray crystallography.Peso molecular:1,012.4 g/molTetanus Toxin (1084-1099)
Tetanus Toxin (1084-1099) is a protein that is derived from the single-chain polypeptide neurotoxin produced by Clostridium tetani. The neurotoxins produced by Clostridium tetani are among the most potent molecules known to humankind. Once in the body, the toxin binds to the basal lamina at the neuromuscular junction. From here, the toxin is transported to inhibitory interneurons in the spinal cord, where it prevents the release of neurotransmitters, which causes spastic paralysis.Peso molecular:1,878.1 g/molCSK substrate
Substrate peptide for C-terminal Src kinase (Csk) for use in kinase assays. Csk is a cytosolic tyrosine kinase that is closely related to the kinase Src and is a well-known negative regulator of Src family kinases. Csk has both tumour suppressor and oncogenic properties and has also been implicated in regulating blood pressure, making Csk a novel therapeutic target for hypertension disorders.
Cor e Forma:PowderPeso molecular:1,504.8 g/molCecropin-B
CAS:Cecropins are a lytic peptide family, originally isolated from Hyalophora cecropia. Cecropin-B is a cationic helical peptide that can form pores, this is believed to be the reason for its such potent lytic activity. Cecropin-B has been shown to be effective against both Gram-positive and Gram-negative bacteria plus numerous cancer cell lines including multidrug-resistant types. The ability to insert into the cell membrane and lead to pore formation is attributed to the amphipathic groups present creating amphipathic regions. The effectiveness of cecropin-B on cancer cells has led to further use of the peptide as a model for potential new anticancer drugs including cyclic cationic forms.
Cor e Forma:PowderPeso molecular:3,832.3 g/molApolipoprotein KV domain (67 - 77)
Vascular lipid deposition and altered lipid profiles are typical when unregulated angiogenesis is occurring, it is often seen in vascular disorders such as cancer and atherosclerosis. Apolipoprotein a (ApoA) functions as part of the lipid transporter complex high-density lipoproteins (HDL) to ensure lipid homeostasis and therefore the balance of angiogenesis. Within ApoA the Kringle5 (KV) domain (67 - 77), also known as KV11, has been identified as the region of ApoA that exerts anti-angiogenic effect. KV11 was shown in tumour cells to inhibit angiogenesis and consequently inhibits tumour progression. KV11 targets the angiogenesis c-Src/ERK pathway by blocking the activation signals received from vascular endothelial growth factor (VEGF). KV11 provides a new research potential for an anti-angiogenesis and anti-tumour therapeutic agent.Peso molecular:1,447.66 g/molAcetyl-Alpha-2-antiplasmin-[AF680]
Alpha-2-antiplasmin (alpha2AP), a member of the serine protease inhibitor (SERPIN) superfamily, is the main inhibitor of the fibrinolytic enzyme plasmin as well as an inhibitor of trypsin, elastase, and C protein. It plays a crucial role in reducing plasmin production and activity and thus inhibiting fibrinolysis.alpha2AP is synthesized in the liver and secreted as a single-chain glycoprotein, containing 11-14% carbohydrate, with a methionine (Met) as its N-terminus (Met-alpha2AP). The N-terminus of alpha2AP is involved in the incorporation of alpha2AP into a clot and the C-terminus is involved in the initial interaction of alpha2AP with plasmin(ogen). Circulating alpha2AP undergoes both N-and C-terminal modifications, which alter its activity. Increased concentrations of a2AP are associated with a higher risk of cardiovascular diseases.Pureza:Min. 95%Peso molecular:2,735.2 g/molH-IANVFTNAFR^-OH
Peptide H-IANVFTNAFR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-CGVNNSNEDFREENLKTAN-NH2
Peptide Ac-CGVNNSNEDFREENLKTAN-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-IAVSYQTK^-OH
Peptide H-IAVSYQTK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.CALCRL Blocking Peptide
A synthetic peptide for use as a blocking control in assays to test for specificity of CALCRL antibody, catalog no. 70R-6003Pureza:Min. 95%H-Nle-2-ClTrt-Resin (200-400 mesh) 1% DVB
H-Nle-2-ClTrt-Resin (200-400 mesh) 1% DVB is a resin that is used as a building block for peptide synthesis. It is an alcohol resin that contains amines, thiols, and alcohols. This resin has been shown to be useful in the synthesis of peptides and proteins.Pureza:Min. 95%H-FTLSVDR-OH
Peptide H-FTLSVDR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fórmula:C37H60N10O12Peso molecular:836.93 g/molMBP MAPK Substrate
Peptide MBP MAPK Substrate is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fórmula:C39H70N18O11Peso molecular:967.11 g/molH-Ser-Leu-Ile-Gly-Arg-NH2
Hypertension is a condition that affects the heart and blood vessels. It is caused by a number of factors, including increased blood pressure, high levels of cholesterol, diabetes, and genetics. Hypertension can lead to stroke, kidney disease, heart failure, or death. This drug was designed to target hypertension by activating protease-activated receptor (PAR) peptides in the body. PAR peptides are found in many tissues throughout the body and are involved in inflammation and coagulation. PAR2 has been shown to be involved in cardiovascular diseases such as atherosclerosis and coronary artery disease. The drug was designed for use as an oral treatment for hypertension and related conditions.Fórmula:C23H45N9O6Pureza:Min. 95%Peso molecular:543.67 g/molH-QGDVFVVPR^-OH
Peptide H-QGDVFVVPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fmoc-Asn(Trt)-Rink-Amide MBHA Resin
Fmoc-Asn(Trt)-Rink-Amide MBHA Resin is an ion channel blocker and a research tool that can be used to study the effects of peptides and other small molecules on ion channels. It is a high purity resin with a CAS number of 47794-33-4. The Fmoc-Asn(Trt)-Rink-Amide MBHA Resin is an inhibitor of the Ca2+ channel and the K+ channel and it can be used in pharmacology, cell biology, and immunology research.Pureza:Min. 95%H-Asp-[Pen-Phe-Trp-Lys-Tyr-Cys]-Val-OH
H-Asp-[Pen-Phe-Trp-Lys-Tyr-Cys]-Val-OH is a peptide that belongs to the class of biochemicals. It is a disulfide-rich peptide that is found in the brain, and has been shown to increase blood flow and activate the hypothalamic pituitary adrenal axis in animals. Urotensin II and related peptides are also found in the brain, but have not been shown to have any effect on blood flow or hormone levels.Fórmula:C52H68N10O12S2Pureza:Min. 95%Peso molecular:1,089.31 g/molH-2Kd Mouse MAGE-A3 SYVKVLHHM
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolH-NLNSLSELEVK^-OH
Peptide H-NLNSLSELEVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
13C-PT630
Peptide 13C-PT630 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Fmoc-Thr(tBu)-Rink-Amide MBHA Resin
Fmoc-Thr(tBu)-Rink-Amide MBHA Resin is a resin that can be used for the synthesis of peptides. It is an inhibitor of Protein interactions, Activator, Ligand, and Receptor. This resin can be used in research to study ion channels and antibodies. Fmoc-Thr(tBu)-Rink-Amide MBHA Resin is also a high purity product with CAS No.Pureza:Min. 95%Fmoc-Asp(OtBu)-Rink-Amide MBHA Resin
Fmoc-Asp(OtBu)-Rink-Amide MBHA Resin is a building block for peptides. It is an acid labile resin that can be cleaved with TFA to provide amine-protected dipeptides and tripeptides. This product is used as a building block for peptide synthesis.
Pureza:Min. 95%Abz-Ser-Pro-Tyr(NO2)-OH
Abz-Ser-Pro-Tyr(NO2)-OH is a peptide that has been shown to be an angiotensin I converting enzyme II (ACE) substrate and an inhibitor of ACE. It also inhibits the release of renin from the juxtaglomerular apparatus, which is needed for the production of angiotensin II. This peptide is used in biochemical research and as a standard for measuring enzymatic activity.Fórmula:C24H27N5O9Pureza:Min. 95%Peso molecular:529.51 g/molH-YGGFLRR^I-OH
Peptide H-YGGFLRR^I-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.SIVmac239 envelope - 85
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:2,160.4 g/molRink-Amide-MBHA Resin (200-400 mesh) 1% DVB
Unsubstituted Resins for Solid Phase Synthesis; 0.3-0.65 meq/gPureza:Min. 95%Ac-CIANHTGVDIHRNGDFQKNG-NH2
Peptide Ac-CIANHTGVDIHRNGDFQKNG-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Tylotoin
Tylotoin is a peptide that has been shown to have a proliferative effect on endothelial cells. It also acts as an inhibitor of cell proliferation in keratinocytes and fibroblasts, without affecting the proliferation of other cell types. Tylotoin is structurally similar to the disulfide-rich peptides from the salamander Tylototriton verrucosus, which are known for their wound healing properties. The proliferative effects of tylotoin are thought to be due to its ability to inhibit the proteolytic enzymes that degrade extracellular matrix proteins in endothelial cells.Fórmula:C59H108N24O16S2Pureza:Min. 95%Peso molecular:1,473.8 g/molH-L^L^IYWASTR^-OH
Peptide H-L^L^IYWASTR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-VYLILEYAPLGTVYR^-OH
Peptide H-VYLILEYAPLGTVYR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-LREQLGPVTQEFWDNLEK^-OH
Peptide H-LREQLGPVTQEFWDNLEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
FOXO3A
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
(Tos-GPR)2-[Rh110]
Fluorogenic substrate for thrombin that when in its intact state does not fluoresce, however upon cleavage by thrombin in 2 successive steps, Rhodamine 110 is released to allow fluorescence.Thrombin is a multifunctional serine protease and is the principal enzyme of hemostasis. It catalyzes the conversion of fibrinogen to fibrin and activates procoagulant factors V, VIII, XI, and XIII. When bound to thrombomodulin, it activates protein C, an anticoagulant zymogen. Thrombin also activates platelets, regulates endothelial cell function, and has a host of direct actions on other cells. Thrombin has been found to act as a mediator of vascular dysfunction and inflammation in both the peripheral and the central nervous systems. Thrombin contributes to the development of cardiovascular disease, atherosclerosis and diabetes and promotes vascular dysfunction, inflammation, and neurodegeneration. Thrombin is elevated in the brains of people with Alzheimer's disease (AD) and therefore may be a therapeutic target in AD.Pureza:Min. 95%Cor e Forma:PowderPeso molecular:1,259.42 g/molSLC38A1 Blocking Peptide
A synthetic peptide for use as a blocking control in assays to test for specificity of SLC38A1 antibody, catalog no. 70R-1754Pureza:Min. 95%Glucagon (1-29)-[Lys(AF647)]
Glucagon (1-29)-[Lys(AF647)] is derived from glucagon, which is a peptide hormone secreted by alpha cells located in the islet of Langerhans region of the pancreas. Glucagon is an essential catabolic hormone that is responsible for the regulation of blood glucose levels. Once released into the bloodstream, glucagon stimulates the production of hepatic glucose, which means it is considered to be a glucose-mobilizing agent. Excessive levels of glucagon can result in the development of hyperglycaemia, since the action of glucagon results in abnormally high blood glucose levels.This peptide contains AF647, structural analog to Alexa Fluor® 647 which is a widely used far-red fluorescent dye.Pureza:Min. 95%Cor e Forma:PowderPeso molecular:4,750 g/molAIP-IV
Staphylococcus aureus is a major human pathogen that utilizes autoinducing peptide (AIP) signals to regulate virulence. Methods to intercept bacterial quorum sensing (QS) aim to find novel anti-virulence treatments.Auto-inducing peptide (AIP) is a cyclic thiolactone quorum sensing peptide from Staphylococcus aureus which is responsible for activating the agr response. AIP is released from the bacteria and its extracellular concentration is then sensed by a two-component system on the bacterial surface, AgrC and AgrA. AgrC is the membrane histidine kinase receptor and AgrA is a response regulator- upon binding of AIP, AgrC phosphorylates AgrA.AIP accumulates during growth activating an AgrC and AgrA cascade when it reaches a critical signal level. This cascade activates P2 and P3 promoters which autoactivate the agr system and upregulate RNAIII transcription. RNAIII regulates the expression of virulence factors including toxins, super-antigens, and exo-enzymes. Extensive research to identify AIP:AgrC inhibitors aims to find therapeutics against pathogens.AgrD is the precursor peptide of AIP, and AgrB is an integral membrane endopeptidase essential to biosynthesize AIP. This AIP system is conserved among many Gram-positive bacteria. S. aureus strains are categorized into four groups (I-IV) according to their AIP signal and cognate extracellular receptor, AgrC. Each group is associated with a certain disease profile, S. aureus group-IV strains have been associated with generalized exfoliative syndromes and osteoarticular infections. AIP-IV has been used to develop antibodies and an effective ELISA help detect AIP-IV levels in the nanomolar range. This can be implemented to identify S. aureus type IV infections in patient samples.
Pureza:Min. 95%Cor e Forma:PowderPeso molecular:1,008.4 g/molhsBCL9CT-24
Blocks the Wnt pathway and inhibits the expression of TGFb1 in CT26 colon carcinoma cells, leading to the reduction of CCL20 and CCL22, two TGF-b- dependent chemokines critical for Treg cell recruitment into the tumour microenvironment. hsBCL9CT-24 shows robust antitumour efficacy across multiple in vivo models.
Pureza:Min. 95%Cor e Forma:PowderPeso molecular:1,629 g/molAngiotensin (Human, 1-7)
CAS:Angiotensin 1-7 (Ang-(1-7)) is a component of the renin angiotensin system RAS. Ang-(1-7) is produced by angiotensin-converting enzyme 2 (ACE2), from the angiotensin II (Ang-II) peptide, as well as by prolylendopeptidase (PEP) and neutral endopeptidase (NEP) which produce Ang-(1-7) directly from angiotensin I (Ang-I).Ang-(1-7) broadly opposes Ang-II actions. Ang-(1-7) has vasodilatory and anti-oxidative effects, and exerts protective actions in hypertension, diabetes, and other cardiovascular disorders, Ang-(1-7) therefore represents a promising therapeutic target for cardiovascular and metabolic diseases. Ang-(1-7) exerts its actions via its G-protein-coupled receptor, Mas. This novel arm of the RAS has effects that counterbalance those mediated by the classical ACE/Ang-II pathway.Fórmula:C41H62N12O11Pureza:Min. 95%Cor e Forma:PowderPeso molecular:899.01 g/molOVA (323-339)
CAS:Ovalbumin (OVA) is the primary protein in egg-white, and is involved in initiating food allergies and asthma. It is a highly immunogenic protein and can be used for peptide conjugation in the development of antibodies.OVA (323-339) is a class I (Kb)-restricted peptide epitope of OVA. The ovalbumin fragment is presented by the class I MHC molecule, H-2Kb.Fórmula:C74H120N26O25Pureza:Min. 95%Cor e Forma:PowderPeso molecular:1,773.93 g/molFmoc-Phe-Ser(Psi(Me,Me)Pro)-OH
CAS:Fmoc-Phe-Ser(Psi(Me,Me)Pro)-OH is a diastereomer of Fmoc-Phe-Ser. It is used as a substrate for peptide synthesis and can be used to synthesize oxytocin receptor antagonists. It has been shown to have high affinity for the oxytocin receptor and inhibits the binding of oxytocin to the receptor by competing with it for the same site on the receptor. This inhibition leads to decreased levels of oxytocin that are responsible for uterine contractions during labour and milk ejection from the breast during breastfeeding. Fmoc-Phe-Ser(Psi(Me,Me)Pro)-OH also has been shown to be useful in filtration techniques such as chlorides, propargylamines, and divalent cyclopentenones.Fórmula:C30H30N2O6Pureza:90%Cor e Forma:White PowderPeso molecular:514.57 g/molDes-n-Octanoyl-[Ser3]-Ghrelin (Rat)
The peptide Des-n-octanoyl-[Ser3]-ghrelin (DOG) is a synthetic analogue of ghrelin, the only known natural ligand for the growth hormone secretagogue receptor. DOG binds to the ghrelin receptor and activates it, thereby stimulating growth hormone release from the anterior pituitary gland. In a rat model, DOG counteracts weight gain caused by high-fat diet. It also increases insulin sensitivity in diabetic rats and acts as an appetite suppressant in non-diabetic rats. As such, this peptide has potential as a therapeutic agent for obesity and diabetes.Fórmula:C139H231N45O41Pureza:Min. 95%Peso molecular:3,188.67 g/molFmoc-Cys(tBu)-Wang Resin (100-200 mesh) 1% DVB
Fmoc-Cys(tBu)-Wang Resin (100-200 mesh) is a research tool for use in the synthesis of peptides and proteins. It is an activated resin that can be used to synthesize peptides with a C-terminal cysteine. The resin is suitable for the coupling of amines, alcohols, thiols, phosphates and other compounds. Fmoc-Cys(tBu)-Wang Resin (100-200 mesh) has been shown to be an effective inhibitor of ion channels and may have potential as a therapeutic drug for the treatment of epilepsy.
Pureza:Min. 95%H-Phe-Pro-OH
CAS:H-Phe-Pro-OH is a cyclic peptide that is a structural mimic of the natural amino acid gamma-aminobutyric acid (GABA) and has been shown to be an effective inhibitor of the p450 enzymes responsible for carcinogen activation. The peptide binds to response elements in DNA and RNA, which prevents transcription of genes that are involved in cancer development. H-Phe-Pro-OH also inhibits collagen production and has hemolytic activity due to hydrogen bonding with erythrocytes. This peptide can be used as an antimicrobial agent against Gram negative bacteria, including Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, and Salmonella typhimurium. In addition, it has been shown to inhibit the growth of Gram positive bacteria such as Staphylococcus aureus and Clostridium perfringens. The mechanism by which this compound inhibits bacterial growth is
Fórmula:C14H18N2O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:262.3 g/molEpitope2-S133-A145-A
Research peptide matching Epitope2-S133-A145-AFórmula:C76H114N20O23SCor e Forma:PowderPeso molecular:1,725.92 g/molRetatrutide
CAS:GLP-1, GIP, and GCGR2 mimic; Obesity research
Fórmula:C221H342N46O68Pureza:Min. 99 Area-%Peso molecular:4,731.33 g/molBID amide
BID (BH3 Interacting Domain Death Agonist) is a pro-apoptotic protein and a member of the BH3-only family, which is part of the larger Bcl-2 family of proteins. BID plays a critical role in the regulation of apoptosis (programmed cell death) by linking two major pathways that trigger cell death: the extrinsic (death receptor-mediated) and intrinsic (mitochondria-mediated) pathways.BID is typically present in an inactive form in the cytosol. In response to death signals from the extrinsic apoptotic pathway, such as when death receptors (e.g., Fas or TNF receptors) are activated, BID gets cleaved by caspase-8. This cleavage produces a truncated, active form of BID called tBID (truncated BID). Once activated, tBID translocates to the mitochondria, where it interacts with pro-apoptotic Bcl-2 family proteins like Bax and Bak. This interaction causes mitochondrial outer membrane permeabilization (MOMP), leading to the release of cytochrome c and other apoptogenic factors from the mitochondria into the cytosol. The release of cytochrome c activates the caspase cascade, which ultimately leads to the execution of apoptosis.Cor e Forma:PowderH3 native 6-peptide mixture
H-STQAAIDQINGK-OHH-STQAAIDQISGK-OHH-SDAPIGK-OHH-DEALNNR-OHH-EFSEVEGR-OHH-TITNDR-OHPeptide purity: >98%AAA: Concentration - Duplicate100 aliquots/pack total to equal 1nmol/peptide/vial dry aliquotsH-Gly-Ala-AMC monohydrochloride
CAS:H-Gly-Ala-AMC monohydrochloride is a chemical that is used as a reaction component or reagent in pharmaceutical and research laboratories. It has been shown to be a useful scaffold for the synthesis of complex compounds. This compound is also used as an intermediate in the synthesis of other fine chemicals. H-Gly-Ala-AMC monohydrochloride can be used as a building block for the production of versatile building blocks, which are useful for making speciality chemicals.Fórmula:C15H17N3O4·HClPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:339.77 g/molH-Glu(Val-OH)-OH
CAS:H-Glu(Val-OH)-OH is a synthetic form of l-glutamic acid. It increases the activity of glutamyl synthetase, which is an enzyme that regulates the synthesis of glutathione. H-Glu(Val-OH)-OH has been shown to have anticarcinogenic effects in animal studies. This compound also inhibits the synthesis of alpha-tocopherol, which is a molecule that protects against oxidative stress and is essential for maintaining cell membranes. H-Glu(Val-OH)-OH may be useful as a dietary supplement for individuals with low body mass index (BMI) or cancer patients undergoing chemotherapy. H-Glu(Val-OH)-OH may be used to treat obesity by increasing energy expenditure and decreasing appetite, although it does not affect glucose levels in mice. The mechanism by which this compound affects obesity is yet unknown, but it may be due to its ability to activate proinflammatory cytokines such as TNFα
Fórmula:C10H18N2O5Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:246.26 g/molH-Thr-Phe-Leu-Leu-Arg-NH2
CAS:H-Thr-Phe-Leu-Leu-Arg-NH2 is a peptide that has been shown to reduce the severity of lung inflammation and injury in rats with pulmonary hypertension. It also prevents the release of proinflammatory cytokines such as tumor necrosis factor alpha (TNFα) and interleukin 6 (IL6). This peptide also induces an antibody response against collagen gel, which is used to treat fibrotic diseases and wounds. The peptide binds to the soybean trypsin inhibitor, preventing it from inhibiting protease enzymes, thereby allowing for protein synthesis. H-Thr-Phe-Leu-Leu-Arg-NH2 has been shown to have antiapoptotic effects by restoring mitochondrial membrane potential in cancer cells. This peptide can be used as a therapeutic agent for various diseases including primary pulmonary hypertension, cancer tissues, and mitochondrial disorders.Fórmula:C31H53N9O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:647.81 g/molBiotin-Substance P
Substance P (SP) is a peptide that is highly conserved across the animal kingdom and is involved in a number of inflammatory and growth promoting processes. SP has a net positive charge at physiological pH, it is an amphiphilic peptide with positively charged residues at the N-terminus and hydrophobic residues at the C-terminus, this controls how it interacts with cell membranes. SP is stable in plasma (several hours) but has a short half-life in tissues (seconds/minutes).SP is encoded by the TAC1 gene and is a member of the tachykinin peptide hormone family. SP is expressed by many cell types including: neurons, astrocytes, microglia, epithelial cells, endothelial cells, immune cells such as T cells and macrophages- dendritic cells and eosinophils and some stem cells and progenitor cells. The huge variety of cell types expressing SP suggest it is involved in a wide variety of physiological and pathophysiological functions.SP mediates its functions by interacting with members of the neurokinin (NK) family of G protein-coupled receptors with high selectivity. Among these, SP binds to NK1R with the highest affinity, this receptor is expressed in a wide range of tissue types.Biotin (B7) has been added to the N-terminus.Fórmula:C73H112N20O15S2Peso molecular:1,573.96 g/molHCV NS4A 1635-1643 (HLA-A*03:01)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolH-HLEINPDHSIIETLR^-OH
Peptide H-HLEINPDHSIIETLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-V^L^QWAKKGYYTMKSN-OH
Peptide H-V^L^QWAKKGYYTMKSN-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Cor e Forma:PowderAc-QIMYNYPAM-OH
Peptide Ac-QIMYNYPAM-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-SLHTLFGDK^-OH
Peptide H-SLHTLFGDK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-TNFDNDIALVR^-OH
Peptide H-TNFDNDIALVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-SPDIYNPQAGSLK^-OH
Peptide H-SPDIYNPQAGSLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.GIP (3 - 42), human
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C214H324N58O63SPeso molecular:4,749.38 g/molH-GVASLFAGR^-OH
Peptide H-GVASLFAGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-EGVLYVGSK^-OH
Peptide H-EGVLYVGSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Histone H3 (1-34)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Fórmula:C144H260N54O44Peso molecular:3,451.98 g/molH-LQDAEIAR^-OH
Peptide H-LQDAEIAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.MART-1 (26-35) (human)
CAS:Native Melan-A (26-35) decapeptide derives from the melanocyte lineage-specific protein Melan-A/MART-1, which is expressed in almost 75-100% of primary and metastatic melanomas. The region 26-35 of Melan-A protein acts as an antigenic peptide that is recognized by CD8+ tumor-reactive cytolytic T lymphocytes (CTLs) for designing antigen-specific cancer vaccines1. It has been shown that CD8+ Melan-A-specific CTLs isolated from melanoma patients efficiently lyse the Melan-A-expressing HLA-A*0201+ melanoma cell line. However, CTLs preferentially recognize the Melan-A (26-35) peptide as compared with the Melan-A (27-35) peptide. Moreover, the Melan-A (26-35) A27L analog (ELAGIGILTV) has a higher binding affinity to HLA-A*0201 than the native Melan-A (26-35) peptide (EAAGIGILTV), and consequently displays more potent antigenicity and immunogenicity. It has been reported that the concentration of Melan-A (26-35) A27L analog required to obtain 50% of maximal antigenic activity (EC50) is 0.01nM, whereas that of the native Melan-A (26-35) peptide is 0.25nM1. Therefore, the relative activity of Melan-A (26-35) A27L analog is 25 fold higher than that of the native Melan-A (26-35) peptide. Furthermore, functional competition assay has shown that the concentration of Melan-A (26-35) A27L analog required to achieve 50% inhibition (IC50) of tumor lysis is 2nM, which is 10 fold lower than that of the native Melan-A (26-35) peptide. Regarding peptide stability in human serum, the half-lifes (t1/2) of the native Melan-A (26-35) peptide and the A27L analog are quite similar (45 and 40min, respectively) as measured by HPLC-ESI-MS, but much higher than that of the Melan-A (27-35) nonapeptide (5min).Fórmula:C42H74N10O14Peso molecular:943.11 g/molH-ELTIGSK^-OH
Peptide H-ELTIGSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Aoa-KKSL-OH
Peptide Aoa-KKSL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Neuromedin B, porcine
Peptide Neuromedin B, porcine is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Fórmula:C52H73N15O12SPeso molecular:1,132.3 g/molSIVmac239 envelope - 87
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:2,317.9 g/molFmoc-Arg(Pbf)-Rink-Amide MBHA Resin
FMOC-Arg(Pbf)-Rink-Amide MBHA Resin is a research tool used in cell biology and pharmacology. It is an activator of ion channels and a ligand for receptors. This resin is used to study protein interactions, antibody specificity, and peptide binding properties. The resin can be used as an inhibitor of the phosphorylation of proteins in cells. FMOC-Arg(Pbf)-Rink-Amide MBHA Resin has been shown to be useful in pharmacology for the treatment of various diseases such as diabetes and hypertension.Pureza:Min. 95%Biot-QEQLERALNSS-OH
Peptide Biot-QEQLERALNSS-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
CMVpp65 - 57 (KVYLESFCEDVPSGK)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,700.9 g/molH-VGYMHWYQQKPGK^-OH
Peptide H-VGYMHWYQQKPGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-SVNELIYK^-OH
Peptide H-SVNELIYK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Neuropeptide-Like Protein 12 (NLP-12) (33-39) (54-60) amide (C. elegans)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:937.05 g/molgp100 (457-466)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Fórmula:C47H85N13O15Peso molecular:1,072.28 g/molGalacto-RGD2
When 99mTc-labeled, this cyclic RGD dimer is a useful tool for tumor imaging. This novel galacto RGD dimer has enhanced hydrophilic properties that improve biodistribution and tumor-imaging in comparison to 3P-RGD2 tracer. This product is available as a trifluoroacetate salt.
Fórmula:C91H137N29O32Pureza:Min. 95%Peso molecular:2,149.24 g/molH-NIIHGSDSVESAEK^-OH
Peptide H-NIIHGSDSVESAEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-S^LSLSPG-OH
Peptide H-S^LSLSPG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.CMVpp65 - 69 (RNGFTVLCPKNMIIK)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,655.2 g/molLeu-Enkephalin acetate
CAS:Leu-Enkephalin is an endogenous opioid peptide that has been shown to produce analgesia, anti-inflammatory effects, and changes in locomotor activity. Leu-enkephalin binds to the kappa opioid receptor, which is found in high concentrations in the caudate putamen and hippocampal formation. The enkephalins are a family of basic proteins with two amino acids linked by a single amide bond. They are peptide hormones that act as neurotransmitters in the central nervous system and peripheral nervous system. Leu-enkephalin is a drug candidate for treatment of infectious diseases such as HIV and malaria. In addition, leu-enkephalin has been shown to have side effect profiles that are less severe than morphine or methadone.Fórmula:C28H37N5O7·C2H4O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:554.64 g/molH-F^VAPFPE-OH
Peptide H-F^VAPFPE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-PALEDLR^-OH
Peptide H-PALEDLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Endothelin-1 (Human) Antiserum
Endothelin-1 (ET-1) is a peptide hormone that stimulates the release of catecholamines from the adrenal medulla, and acts as a vasoconstrictor. ET-1 is a potent activator of endothelin receptor type A (ETA), which causes vasoconstriction and bronchoconstriction. The antibody recognizes human ET-1 and does not cross react with other endothelin peptides. This antibody can be used for the detection of ET-1 in tissues or cell culture supernatants. It can also be used to purify recombinant human endothelin or ET receptor subtypes.Pureza:Min. 95%H-IEIPLPFGGK-OH
Peptide H-IEIPLPFGGK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Fórmula:C52H81N11O12Peso molecular:1,070.28 g/molH-QLLQHLIGL-OH TFA salt
Peptide H-QLLQHLIGL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fórmula:C48H81N13O11Peso molecular:1,034.25 g/molH-LCPGNKYEM-OH TFA salt
Peptide H-LCPGNKYEM-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fórmula:C45H69N11O13S2Peso molecular:1,054.24 g/molH-TSALLAGTITSGWTF-OH
Peptide H-TSALLAGTITSGWTF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fórmula:C70H106N16O21Peso molecular:1,525.7 g/mol
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