Peptídeos
Subcategorias de "Peptídeos"
Foram encontrados 29681 produtos de "Peptídeos"
H-ILGFVFTL^T-OH
Peptide H-ILGFVFTL^T-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Spexin
Spexin is a neuropeptide that is conserved amongst humans and rodents. Spexin activates galanin2/3 receptors, inducing a different active conformation of GalR2 to galanin. The broad distribution of spexin suggests multiple physiological roles including as a regulating factor in obesity and energy metabolism. Spexin is ubiquitously expressed in human tissue, however, a correlation has been found with obesity and age. Obese patients had significantly lower levels of circulating spexin than those with a healthy weight range. The significance of this suggests spexin regulates appetite, feeding behaviour, and energy expenditure. Spexin also specifically inhibits the uptake of long-chain fatty acids by adipocytes.Spexin is a central modulator of cardiovascular and renal function and can elicit central nervous system behavioural responses. As spexin levels decrease with age there is research to understand if it plays a role in age-related pathophysiology of cardiometabolic conditions. Spexin is also being considered an early biomarker for cardiovascular disease due to the magnitude with which it decreases as the pathophysiology progresses.Peso molecular:1,618.8 g/molAc-CENQIYDLPEGAHEHFPV-OH
Peptide Ac-CENQIYDLPEGAHEHFPV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-G^P-OH
Peptide H-G^P-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-ELQDLALQGAK^-OH
Peptide H-ELQDLALQGAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-VVGAGDVGK^-OH
Peptide H-VVGAGDVGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
PAR-4 Agonist (Mouse)
CAS:Thrombin is the main effector of the coagulation cascade- it is a serine protease. Thrombin binds to active protease activated receptor (PAR) which belongs to a subfamily of G-protein coupled receptors (GPCR). Thrombin activation of mouse PAR-4 reveals an amino terminus sequence of GYPGKF. This is the natural ligand for PAR-4. GYPGKF binds internally to the receptor and leads to signalling activation. Identification of GYPGKF as a PAR-4 agonist has allowed better understand of the function of PAR. Addition of GYPGKF to PAR-4 expressing cell lines achieved 55% of the maximal response of thrombin. GYPGKF can provide understanding of PAR-4 and a template for more potent agonists.
Fórmula:C33H46N8O7Cor e Forma:PowderPeso molecular:666.3 g/molH-EFSEV^EGR-OH
Peptide H-EFSEV^EGR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Biot-EGPWLEEEEAYGWMDF-NH2
Peptide Biot-EGPWLEEEEAYGWMDF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-LLVYTILPDGEVVGDSAK^-OH
Peptide H-LLVYTILPDGEVVGDSAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
VP1 14-22 (HLA-B*07:02)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolAcetyl-Histone H4 (1-21)
Histone 4 (H4) is one of the four core histones (H2A, H2B, H3 and H4) which are essential for compacting eukaryotic DNA into the nucleosome. Due to the high lysine and arginine content, histones have a net positive charge and therefore electrostatically interact with negatively charged DNA. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core. Like other core histones, H4 has a globular domain and a flexible N-terminal domain, the histone tail, which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination.Gene transcriptional activation or inactivation is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes. Both processes function to alter the positioning of the nucleosome, allowing the DNA within to be either accessible to the transcription machinery or inaccessible. H4 lysine rich tail plays a role in the higher order chromatin folding.Acetyl-Histone H4 (1-21)-has an uncharged C-terminal amide and is protected from N-terminal modifications by a covalently bonded acetyl group.Peso molecular:2,131.3 g/molSETD8 Peptide
Setd8 is a member of the SET domain containing family of proteins and is the sole methyltransferase that catalyses monomethylation of lysine 20 on histone H4 (H4K20me1). This histone modification is involved in regulating DNA replication, chromosome condensation and gene expression.Setd8 is widely expressed and in addition to modifying histone H4, it can modify non-histone proteins, including p53. Setd8 has been shown to play a role in maintaining skin differentiation and is dysregulated in multiple cancer types.Peso molecular:1,076.7 g/molH-HSVVVPYEPPEAGSEYTTIHYK^-OH
Peptide H-HSVVVPYEPPEAGSEYTTIHYK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Ac-DRVYIHPF-OH
Angiotensin II plays an essential role in the maintenance of blood pressure and blood volume. It is a peptide hormone that causes vasoconstriction, a sensation of thirst, and stimulation of the adrenal cortex and aldosterone.
Derived from the cleavage of angiotensin I by the angiotensin converting enzyme, angiotensin II is involved in the renin-angiotensin system (RAS).
Angiotensin II is the subject of much scientific research and is already the target of many anti-hypertensive drugs (ACE inhibitors, ARBs or AT1 receptor antagonists).(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino ]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C47H70N14O10Peso molecular:991.17 g/molH-RHSVV-NH2
Peptide H-RHSVV-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Proto-oncogene PIM1 (191-199)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolH-TVQDALSSVQESDIAVVAR^-OH
Peptide H-TVQDALSSVQESDIAVVAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
h-Chemerin-9 (149-157)
A Chemerin-9 peptide derived from chemerin, a protein that is involved in a variety of functions such as autocrine, angiogenic, reproductive and chemotactic processes. Chemerin-9 binds to the chemerin receptor 23 (G-protein coupled receptor) and causes the receptors internalisation.Peso molecular:1,063.5 g/molH-EIPISINYR^-OH
Peptide H-EIPISINYR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.(Asn670,Sta671,Va672)-Amyloid β/A4 Protein Precursor770 (662-675) ammonium salt
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C73H118N16O27Peso molecular:1,651.83 g/molHXB2 gag NO-68
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,692.1 g/molH-CDDYYYGFGCNKFGRPRDD-NH2
Peptide H-CDDYYYGFGCNKFGRPRDD-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-VLLQTLR^-OH
Peptide H-VLLQTLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Biot-RRRVTSAARRS-NH2
Peptide Biot-RRRVTSAARRS-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-DAAQK^-OH
Peptide H-DAAQK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-AVLTIDK^K^-OH
Peptide H-AVLTIDK^K^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-LLFNK^VTLA-OH
Peptide H-LLFNK^VTLA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
SIVmac239 - 73
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,861.1 g/molH-RHFWQQDEPPQSPWDR^-OH
Peptide H-RHFWQQDEPPQSPWDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-DIEVQGFR^-OH
Peptide H-DIEVQGFR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.HLA-A*02:01 HBV core (18-27)
HLA-A*02 is a class I major histocompatibility complex (MHC) allele which is part of the HLA-A group of human major histocompatibility complex (MHC) leukocyte antigens (HLA). HLA-A is a human MHC class I cell surface receptor and is involved in presenting short polypeptides to the immune system. These polypeptides are typically 7-11 amino acids in length and originate from proteins being expressed by the cell. Cytotoxic T cells in the blood "read" the peptide presented by the complex and should only bind to non-self peptides. If binding occurs, a series of events is initiated culminating in cell death via apoptosis. This peptide corresponds to the Hepatitis B variant (HBV) core sequence which is presented on the MHC class I antigen HLA-A*02.Peso molecular:1,154.6 g/molH-VTVFPIGIGDR^-OH
Peptide H-VTVFPIGIGDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-SLDNGGYYISPR^-OH
Peptide H-SLDNGGYYISPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
LCBiot-EAQQHLLQLT-NH2
Peptide LCBiot-EAQQHLLQLT-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Urumin
Urumin is a veridical host defence peptide against influenza A virus.The peptide specifically targets the evolutionarily conserved H1 hemagglutinin stalk region of H1-containing influenza A viruses.Urumin has been used against drug-resistant influenza A viruses that are resistant against oseltamivir, zanamivir and peramivir. While its mechanism of action is not fully understood, urumin seems to inhibit viral growth by physically destroying influenza A virions, and is able to protect naive mice from doses of influenza A infection as high as 2 times the LD50. Because of its specific targeting of the hemagglutinin stalk region of the influenza A virus, the mechanism of action of urumin is similar to that of antibodies induced in the body by universal influenza vaccines.Peso molecular:2,959.4 g/molAlbumin (mouse, rat)
Albumin is a family of globular, water soluble, un-glycosylated proteins commonly found in blood plasma. Albumins generally act as transport proteins that bind to various ligands to transport them around.The most common member of this family is serum albumin. Serum albumin is produced by the liver and is the most abundant plasma protein, it provides oncotic pressure, transports bilirubin, steroids, fatty acids, thyroid hormones and other hormones, and serves as an extracellular antioxidant agent.Too much or too little circulating serum albumin may be harmful. Perturbations in serum albumin concentration is associated with both type 2 diabetes and metabolic syndrome (MetS). Increase in serum albumin concentration might protect against early glycemic deterioration and progression to type 2 diabetes even in subjects without MetS. Albumin in the urine usually denotes the presence of kidney disease.Peso molecular:1,055.7 g/molH-FASFEAQGALANIAVDK^-OH
Peptide H-FASFEAQGALANIAVDK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-QFPILLDFK^-OH
Peptide H-QFPILLDFK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
HIV p17 Gag (77-85)
The HIV gag gene encodes p17 and p24. P17 Gag is a matrix protein that is vital to HIV life cycle, it targets viral RNA to the nucleus and Gag polyproteins to the cell membrane- p17 Gag accumulates in the extracellular space of tissue while interacting with receptors on various cell types to deregulate cell function.During HIV infection the cytotoxic T lymphocyte (CTL) response is key to attenuating viral replication. CTL recognition epitope of p17 Gag is identified as residues 77-85 to activate the immune response. HIV p17 Gag CTL epitope has been used in IgG titres and has been suggested as a suitable prognostic tool for onset of AIDS. A high affinity of IgG for p17 Gag was correlated to patients remaining in an asymptomatic state. p17 Gag epitope has been shown to induce a strong CTL response in the majority of chronically infected HIV patients. This makes the p17 Gag epitope a target for molecular therapy for HIV treatment and potentially a vaccine development.Cor e Forma:PowderPeso molecular:980.5 g/molSynthetic SAA1 (1-76) protein (Human)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:8,575.21 g/molHistone H4 (1-23)
Histone 4 (H4) is one of the four core histones (H2A, H2B, H3 and H4) which are fundamental in compacting eukaryotic DNA into the nucleosome. Due to the high lysine and arginine content, histones have a net positive charge and therefore electrostatically interact with negatively charged DNA. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core. Like other core histones, H4 has a globular domain and a flexible N-terminal domain, the histone tail, which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination.Gene transcriptional activation or inactivation is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes. Both processes function to alter the positioning of the nucleosome, allowing the DNA within to be either accessible to the transcription machinery or inaccessible. H4's lysine rich tail plays a role in the higher order chromatin folding.Cor e Forma:PowderPeso molecular:2,400.5 g/molH-APGLTQALNTK^-OH
Peptide H-APGLTQALNTK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.LCBiot-FPWFPLPSPYGN-OH
Peptide LCBiot-FPWFPLPSPYGN-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-VQSLQDEVAFLR^-OH
Peptide H-VQSLQDEVAFLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Myelin PLP (139-151)
CAS:Myelin PLP (139-151) is a basic protein that belongs to the family of oligodendrocyte-myelin glycoproteins. It has been shown to activate toll-like receptor, which is a pattern recognition receptor that recognizes invading pathogens and triggers an immune response. Myelin PLP (139-151) may play a role in the development of autoimmune diseases, as it has been found to be a target for autoantibodies. It has also been shown to have antioxidative properties, which may help prevent free radical damage in the brain and other tissues. The monoclonal antibody against this protein can be used for immunohistological analysis.Fórmula:C72H104N20O17Pureza:Min. 95%Peso molecular:1,521.72 g/molHIV - 1 MN ENV - 131
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,310.5 g/molH-LSTQNVIDAEK^-OH
Peptide H-LSTQNVIDAEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.SIVmac239 - 28
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,636.9 g/molAra h 2 (147-155) peanut Allergen
Ara h 2 is one of the major allergenic proteins from peanut (Arachis hypogaea) which contains approximately 13 potential allergenic proteins.Ara h 2 is a member of the 2S albumins (conglutinins) belonging to the prolamin superfamily which also includes Ara h 6. 2S albumins contain major food allergens from seeds of many mono- and dicotyledon plants and share a common compact structure that renders the proteins highly resistant to proteolysis.In mouse models Ara h 2 and Ara h 6 are the main cause of effector responses such as mast cell degranulation and anaphylaxis. Ara h 2 has a high predictive value for diagnosis of clinical peanut allergy and is also more potent than Ara h 1 or Ara h 3 in histamine release assays and skin prick tests.This peptide represents a tryptic peptide of Ara h 2.Cor e Forma:PowderPeso molecular:1,027.5 g/molH-ATLTVDK^-OH
Peptide H-ATLTVDK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-AVPI-NH2
Peptide H-AVPI-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Fmoc-L-Glu(OtBu)-Wang Resin (100-200 mesh) 1% DVB
Fmoc-Glu(OtBu)-Wang Resin (100-200 mesh) 1% DVB is a synthetic resin that is used in the synthesis of peptides. It is an activator for the coupling of peptide side chains to amino acid residues. This resin has been shown to be useful as an antibody immobilization and purification agent, and can also be used as a high-purity ion channel inhibitor. Fmoc-Glu(OtBu)-Wang Resin (100-200 mesh) 1% DVB is highly soluble in water, making it an ideal material for use in life science applications such as cell biology and pharmacology.Pureza:Min. 95%H-R^PPGFSPFR-OH
Peptide H-R^PPGFSPFR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-LNALKPDNR^-OH
Peptide H-LNALKPDNR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-EP^QVYTLPPSR^-OH
Peptide H-EP^QVYTLPPSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
[5-FAM] Kemptide
Kemptide is a synthetic substrate of the PKA catalytically active subunit (PKAc), and can bind along with ATP to PKAc. It contains 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag.
Peso molecular:1,129.5 g/molPEN-FFW
Sal-like4 (SALL4) derived peptide able to antagonise the SALL4-NuRD complex in hepatocellular carcinoma, turning SALL4 from a dual transcription repressor-activator to a singular transcription activator. Displays antitumour effects in xenograft mouse models.Cor e Forma:PowderTAT-TRPV1 (736-745)
TAT-TRPV1 (736-745) is a cell-permeable TRPV1 fragment (capsaicin receptor and the vanilloid receptor 1), that can inhibit the interaction of TRPV1 and A-kinase anchoring protein 79 (AKAP79). TAT- TRPV1 (736-745) consists of amino acids 736-749 from the TRPV1 C-terminal domain, combined with amino acids 47-57 of TAT to promote uptake across neuronal cell membranes. TAT-TRPV1 (736-745) inhibits both the first and the second phase of pain behaviour in the formalin test, implying an effect on both acute and inflammatory pain.A-kinase anchoring protein 79 (AKAP79) is a protein that targets kinases to TRPV1. Inflammation causes hyperalgesia but can be reduced when TRPV1 is blocked. a key region on AKAP79, amino acids 326-336, is responsible for its interaction with TRPV1. TAT-TRPV1 (736-745) promotes uptake across the cell membrane and TRPV1 (736-745) inhibited inflammatory hyperalgesia in mice. TAT-TRPV1 (736-745) did not affect pain thresholds in the absence of inflammation. These results suggest that antagonizing the TRPV1-AKAP79 interaction will be a useful strategy for inhibiting inflammatory hyperalgesia and TAT is an effective delivery system.
Peso molecular:2,927.6 g/molH-NTTGALTTR^-OH
Peptide H-NTTGALTTR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-KITDFGRAK^-OH
Peptide H-KITDFGRAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
TAT-NR2B (C-ter)
N-methyl-D-aspartate receptors (NMDARs) are ligand-gated ionotropic glutamate receptors that mediate excitatory synaptic transmission and play important roles in many aspects of nervous system function including: synaptic plasticity- learning and memory- neuronal development and circuit formation. NMDARs have been implicated in various neuronal disorders. NMDARs are heteromers consisting of an obligate NR1 subunit and most commonly one or two kinds of NR2 subunits or occasionally NR3 subunits. NR2B is the predominant subunit found in the postnatal brain, however over time the number of NRA2 subunits increase and eventually outnumber NR2B subunits in a process known as the NR2B-NR2A developmental switch. The greater ratios of the NR2B subunit in post-natal brains leads to NMDA receptors which remain open longer compared to those with more NR2A subunits, this may be related to the greater memory abilities in the immediate postnatal period compared to late in life. NR2B improves synaptic plasticity and memory when over-expressed in neurones. The involvement of NMDAR in the central nervous system (CNS) has become a focus area for neurodegenerative diseases such as Alzheimer's disease, epilepsy and ischemic neuronal cell death.The TAT peptide is present due to its properties as a cell penetrating cationic peptide (CPP). It derived from the N-terminus of the Tat protein, which is a trans-activator of the transcription protein present in the human immunodeficiency virus (HIV). As a CPP, TAT is able facilitate the delivery of NR2B (C-ter) across the plasma membrane.Cor e Forma:PowderPeso molecular:2,517.4 g/molH-LVVVGAGDVGK^-OH
Peptide H-LVVVGAGDVGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-GDYPLEAVR^-OH
Peptide H-GDYPLEAVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-MDRTSASQQSNYGKC-NH2
Peptide H-MDRTSASQQSNYGKC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-YARAAARQARAKAL^ARQL^GVAA-OH
Peptide H-YARAAARQARAKAL^ARQL^GVAA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.[Azhx]-ANP (Human)
ANP (human) is derived from the atrial natriuretic peptide (ANP) which is a cardiac hormone involved in maintaining cardio-renal homeostasis. This occurs through the activation of the guanylyl cyclase-coupled receptor, resulting in the increased concentration of cyclic guanylate monophosphate. Moreover its function in the processes of anti-proliferation and anti-angiogenesis allow it to take part in cardiovascular remodelling.ANP is a member of the natriuretic peptide family and it is encoded by the NPPA gene, located on chromosome 1. Once synthesized from the 151 amino acid pre-prohormone into its biologically active form, ANP is secreted by the atrial cardiomyocytes in the circulating forms: ANP (1-98) and ANP (99-126). This synthesis process involves the signal peptide being removed from the pre-prohormone resulting in pro-ANP (1-126) which is converted into the circulating forms by the type II transmembrane serine protease Corin.At the N-terminus Azhx, 6-azidohexanoic acid, is present.
Peso molecular:3,219.5 g/molThrombin Receptor Antagonist
Thrombin is the main effector of the coagulation cascade- it is a serine protease. Thrombin binds to active protease activated receptor 1 (PAR-1) which belongs to a subfamily of G-protein coupled receptors (GPCR). However, thrombin generated during cardiopulmonary bypass can activate PAR-1 leading to platelet dysfunction and unwanted bleeding. FLLRN is found to be a potent PAR-1 antagonist. Use of FLLRN and variants has aided the study of platelet aggregation dynamics. Further study may provide a suitable clinical application.Peso molecular:661.4 g/molH-LAAFPEDR^-OH
Peptide H-LAAFPEDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.HXB2 gag NO-119
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,799.1 g/molH-DYVSQFEGSALGK^^^-OH
Peptide H-DYVSQFEGSALGK^^^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.[5-FAM]/[Lys(Dabcyl)]-CoV Main Protease (Mpro) Substrate
FRET peptide substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro). The substrate sequence is derived from residues P4-P5' of the SARS-CoV Mpro N-terminal autoprocessing site which has the sequence AVLQSGFRK. SARS-CoV Mpro is a key antiviral target.This peptide contains an N-terminal 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag and the Dabcyl fluorescence quencher. When the peptide is intact, fluorescence is undetectable due to the proximity of the Dabcyl quencher to the 5-FAM fluorophore. However upon cleavage of the peptide by SARS-CoV Mpro, the 5-FAM group and the Dabcyl quencher are separated and fluorescence can be detected. This therefore represents a useful tool for investigating SARS-CoV Mpro activity.Cor e Forma:PowderPeso molecular:1,740.8 g/molMAGE-A4 230-239 (HLA-A*02:01)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,132.2 g/molSpy-Tag peptide
SpyTag is a short peptide derived from the CnaB2 domain of the fibronectin-binding protein FbaB protein from Streptococcus pyogenes. The CnaB2 domain has a spontaneous isopeptide bond between Lys and Asp. By splitting and rational deisgn of this domain, the peptide (SpyTag) can be used in a pair to form an amide bond to its protein partner (SpyCatcher) in minutes. This ability to self-assemble through spontaneous isopeptide bond formation works across a wide range of aqueous buffer, pH and temperatures. Thsi system is therfore a valuable conjugation tool for biotechnolgy and bioengineering.Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesinB. Zakeri, J.O. Fierer, E. Celik, E.C. Chittock, U. Schwarz-Linek, V.T. Moy, M. Howarth, Proc. Natl. Acad. Sci. U.S.A.109 (12) E690-E697 Catalyst-free thiazolidine formation chemistry enables the facile construction of peptide/protein-cell conjugates (PCCs) at physiological pH X Liu, Y Wang, B Ye, X Bi - Chemical Science, 2023 - pubs.rsc.orghttps://pubs.rsc.org/en/content/articlehtml/2023/sc/d3sc01382k AlbuCatcher for Long-Acting Therapeutics JH Rho, JH Lee, I Kwon - ACS omega, 2024 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acsomega.4c02303 T Cell Activating Thermostable Self-Assembly Nanoscaffold Tailored for Cellular Immunity Antigen Delivery J Zhang, J Yang, Q Li, R Peng, S Fan, H Yi - Advanced , 2023 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202303049Cor e Forma:PowderClickable-TAT Azide (49-57)
Modified HIV TAT Sequence 49-57 for Click Chemistry. Product available as a trifluoroacetate salt
Fórmula:C58H114N34O11Pureza:Min. 95%Peso molecular:1,463.78 g/mol[5-FAM]-VGB4
Antagonist peptide of VEGF-A and VEGF-B reproducing two binding regions of VEGF-B (loop 1 and loop3) linked together by a receptor binding region of VEGF-A (loop3). Binds to both VEGFR1 and VEGFR2 and inhibits VEGF-A driven proliferation, migration and tube formation in HUVECs. It contains 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.Peso molecular:3,066.5 g/molLasioglossin-III
Lasioglossin-III (Lasio-III) is a naturally-occurring salt-resistant anti-microbial peptide (AMP) found in-Lasioglossum laticeps-(broad-faced furrow bee). Lasioglossin-III has broad spectrum anti-microbial activity and anti-biofilm properties against Gram negative and Gram positive bacteria, including strong anti-microbial activity against-E. coli,-S. aureus, and-P aeruginosa-under physiological salt concentration, with low toxicity.AMPs form an important part of the innate immune system in plants, animals and insects-and are reported to be effective even against several antibiotic resistant strains due to differing modes of pathogen killing from those of conventional antibiotics. Lasio-III has a membranolytic mode of action. It can bind both the outer and inner membranes of bacteria. Lasio-III possesses a fast killing ability toward both Gram positive and negative bacteria compared to many other active AMPs.Peso molecular:1,764.2 g/mol5(6)-carboxyfluorescein-(Cys-Gln-Thr-Pro-Tyr-Tyr-Met-Asn-Thr-Cys)-OH
5(6)-carboxyfluorescein-(Cys-Gln-Thr-Pro-Tyr-Tyr-Met-Asn-Thr-Cys)-OH is a peptide that is used to study protein and peptide interactions. This compound can be used as a fluorescent probe for detecting the presence of specific proteins. 5(6)-carboxyfluorescein-(Cys-Gln-Thr-Pro-Tyr-Tyr-Met-Asn-Thr-Cys)-OH also has antiapoptotic activity, which may be due to its ability to inhibit the release of cytochrome c from mitochondria, thereby preventing activation of caspases. This peptide binds to phospholipids in the plasma membrane and can be used as a cell penetrating peptide (CPP).Fórmula:C72H82N12O23S3Pureza:Min. 95%Peso molecular:1,579.71 g/molH-GLPSSIEK^-OH
Peptide H-GLPSSIEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-VFIGVNDLER^-OH
Peptide H-VFIGVNDLER^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.SIVmac239 - 16
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,509.8 g/molH-TFDEIASGFR^-OH
Peptide H-TFDEIASGFR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.[Aurora™ Fluor 647]-RGD peptide
The RGD motif has been found in wide range of eukaryotic proteins allowing cell adhesion to the ECM. The tripeptide RGD is the primary domain to bind integrin found in extracellular matrix (ECM) proteins including fibronectin, fibrinogen and osteopontin. It has been shown to effectively adhere various cell types to a wide range of biomaterials. This is a key research tool in the flourishing area of tissue engineering and wound healing using synthetic peptides that are either inert or can be potentially beneficial. RGD is a suitable ligand for targeting nanomolecules and cancer drugs to specific tissues due to its biocompatibility and safety.This RGD peptide is supplied with an Aurora Fluor 647 fluorophore attached and produced to research grade quality. Aurora Fluor 647 excitation suited to 594nm and emission peaked at 671nm. The Molecular Probes Alexa Fluor dyes provide a number of benefits including: more intense fluorescence than other spectrally similar conjugates better photostability, allowing more time for image capture availability of conjugates in an array of distinct fluorescent colours from blue to infrared- and pH insensitivity that enables the dyes to remain highly fluorescent over a broad pH range and high water solubility.Cor e Forma:PowderTKD (450-463)
Heat shock proteins (Hsps) are highly conserved and stress inducible. Hsp70 has been found in tumour cell lines to be highly expressed with a higher plasma membrane localisation. This is correlated to the cell sensitivity to natural killer (NK) cell-mediated lysis. Investigation identified that Hsp70 N-terminal extended peptide TKD (450-463) was critical for this to occur. TKD (450-463) with low dose interleukin (IL-2) has the same capacity to induce NK cell proliferation and activity as the full-length protein Hsp70. Excess of Hsp70 and TKD (450-463) both inhibit cytolytic activity by NK cells. Other related sequences tested did not lead to NK cell-mediated lysis. Further study with the TKD (450-463) epitope could elucidate how NK cells are activated by Hsp70s as the mechanism remains unclear.Peso molecular:1,562.8 g/molPantinin-2
Pantinin-2, like other pantinin peptides, has high activity against Gram-positive bacteria yet weak activity against Gram-negative bacteria. Pantinin-2 also displays activity against Candida tropicalis and has relatively mild haemolytic activity against human red blood cells.Cor e Forma:PowderPeso molecular:1,403.8 g/molH-VPFLVAETPR^-OH
Peptide H-VPFLVAETPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-ILSPFLP^LL-OH
Peptide H-ILSPFLP^LL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.ACTH (7-38) Human
Segment 7-38 of adrenocorticotropic hormone (ACTH). ACTH, also known as corticotropin, is a cleavage product from a larger precursor proopiomelanocortin (POMC). This 39 amino acid-peptide hormone is produced in the anterior pituitary gland upon stimulation by the corticotropin releasing hormone from the hypothalamus in response to stress. It stimulates the secretion of steroid hormone, specifically glucocorticoids in the adrenal cortex by acting through a cell membrane receptor (ACTH-R). In mammals, the action of ACTH is limited to those areas of the adrenal cortex in which the glucocorticoid hormones cortisol (hydrocortisone) and corticosterone are formed. ACTH has little control over the secretion of aldosterone, the other major steroid hormone from the adrenal cortex.Peso molecular:3,659.11 g/molH-Thr-Phe-Leu-Leu-Arg-NH2
CAS:The endothelium is a layer of cells that lines the inner surface of blood vessels and lymphatic vessels, forming a barrier between circulating blood or lymph and the rest of the body. It is involved in maintaining vascular homeostasis as well as in inflammation. The endothelium regulates vascular tone and blood pressure through release of nitric oxide (NO) and other substances, such as prostacyclin, vasoactive peptides, endothelin-1, tumor necrosis factor-α, interleukin-1β, and thromboxane A2. Endothelial cells are activated by various means such as increased intracellular Ca2+ concentration or basic fibroblast growth factor (bFGF). This activation can be inhibited by receptor antagonists such as neurokinin-1 receptor antagonists.Fórmula:C31H53N9O6Pureza:Min. 95%Peso molecular:647.81 g/molH-VPGVG^-OH
Peptide H-VPGVG^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-WDWDWDWDWDWDWDWDWDWD-NH2
Peptide Ac-WDWDWDWDWDWDWDWDWDWD-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-ESSSHHPGIAEFPSR^-OH
Peptide H-ESSSHHPGIAEFPSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Biotin-PEG2-Claudin-9
Biotin-PEG2-Claudin-9 is derived from the tight junction protein Claudin-9 which is encoded by the CLDN6 gene and can be found within epithelial cell to cell contacts. Structurally, the Claudin family, of which Claudin-9 is a member, are transmembrane proteins containing two extracellular loops and are involved in maintaining cell polarity and controlling paracellular ion flux.Reduction in the number of Claudins has been associated with tumour formation. This may be due to Claudin role in maintaining cell detachment and migration.Claudin-9 has been shown to be overexpressed in hepatocellular carcinoma (HCC) and has the ability to increase the metastasis of hepatocytes. It further influences the activation of the Stat3 signalling pathway through tyrosine kinase 2. Overall CLDN9 demonstrates itself to be a HCC proto-oncogene.This peptide has a covalently bonded N-terminal Biotin tag that can be used for detection and purification and contains a polyethylene glycol spacer (PEG2).Cor e Forma:PowderPeso molecular:2,881.5 g/molAc-AAA-NH2
Peptide Ac-AAA-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Ac-RLR-[AMC] Proteasome Substrate
Fluorogenic substrate peptide to assay trypsin-like activity. In its intact state this peptide is non-fluorescent, however when aminomethylcoumarin (AMC) is released upon hydrolysation, fluorescence can be detected. This peptide is therefore a useful tool for analysing trypsin-like enzyme activity.AMC is a fluorescent dye with excitation maxima at around 360 nm and emission maxima at around 450 nm. AMC can be excited with a mercury lamp and observed using a UV filter set.Peso molecular:642.4 g/molH-LKLKSIVSWAKKVL-NH2
Peptide H-LKLKSIVSWAKKVL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-TGISPLALIK^-OH
Peptide H-TGISPLALIK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
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