Peptídeos
Subcategorias de "Peptídeos"
Foram encontrados 29623 produtos de "Peptídeos"
Val-Ile-Pro
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C16H29N3O4Peso molecular:327.42 g/molH-AEDVCDLP-NH2
Peptide H-AEDVCDLP-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Melanocyte Protein PMEL 17 (256-264)
CAS:Peptide H-YLEPGPVTA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Fórmula:C44H67N9O14Peso molecular:946.05 g/molAc-Qpr-NH2
Peptide Ac-Qpr-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-TNQELQEINR^-OH
Peptide H-TNQELQEINR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.AF488 NHS Ester
CAS:Please enquire for more information about AF488 NHS Ester including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C25H17N3O13S2Pureza:Min. 95%Peso molecular:631.5 g/molH-YVTSAPMPEPQAPGR^-OH
Peptide H-YVTSAPMPEPQAPGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-ATADDELSFK^-OH
Peptide H-ATADDELSFK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.AF488 DBCO
CAS:AF488 DBCO is a water-soluble, green-fluorescent probe for copper-less detection of azide-tagged biomolecules. This probe is water-soluble and its fluorescence is pH independent over a wide pH range. The brightness and photostability of blue dyes are best suited to direct imaging of low-abundance targets.Fórmula:C39H28N4O11S2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:792.8 g/molLLPG
CAS:Please enquire for more information about LLPG including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C30H30N4O8Pureza:Min. 95%Peso molecular:574.58 g/molH-Ser-Asp-OH
CAS:H-Ser-Asp-OH is a peptide that is the product of the prokaryotic gene, mycobacterium avium. It has been shown to inhibit the translation of mRNA into protein in mycobacteria. H-Ser-Asp-OH also has an anti-inflammatory effect on human cells by inhibiting the synthesis of prostaglandins. This peptide also has antiviral properties and can be used as a treatment for chronic kidney disease (CKD) and hepatitis C. The drug is not effective against HIV infection or hepatitis B virus, however, because it does not inhibit reverse transcriptase or bind to viral DNA.Fórmula:C7H12N2O6Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:220.18 g/molGluten Exorphin B5 H-Tyr-Gly-Gly-Trp-Leu-OH
CAS:Gluten Exorphin B5 H-Tyr-Gly-Gly-Trp-Leu-OH is a synthetic opioid peptide that has been shown in animal models to reduce food intake and body weight. This peptide is an analog of the endogenous opioid peptides Met-enkephalin and Leu-enkephalin, which have been implicated in the regulation of food intake and energy expenditure. Gluten exorphin B5 H-Tyr-Gly-Gly-Trp-Leu-OH binds to the μ opioid receptor, which is involved in drug safety. It also binds to the prolactin receptor, which plays a role in drug absorption and distribution.Fórmula:C30H38N6O7Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:594.66 g/molH-FSLVGIGGQDLNEGNR^-OH
Peptide H-FSLVGIGGQDLNEGNR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-NIETIINTFHQYSVK^-OH
Peptide H-NIETIINTFHQYSVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-IYLYTLNDNAR^-OH
Peptide H-IYLYTLNDNAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Glutaryl-Gly-Arg-AMC hydrochloride salt
CAS:Glutaryl-Gly-Arg-AMC hydrochloride salt is a high quality, fine chemical reagent that is useful as a building block, scaffold or intermediate. It has been used in the synthesis of other complex compounds and has been shown to have potential for use in drug discovery research. Glutaryl-Gly-Arg-AMC hydrochloride salt is a versatile building block that can be used in reactions that require the presence of an amine group, such as peptide coupling. This reagent can also be used to modify the functional groups on small molecules, such as aldehydes and carboxylic acids. Glutaryl-Gly-Arg-AMC hydrochloride salt is also useful as a reaction component in the synthesis of speciality chemicals, such as pharmaceuticals and agrochemicals.Fórmula:C23H30N6O7•HClPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:538.98 g/molAc-IEEVD-OH
Peptide Ac-IEEVD-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-DAEFRHDSGYEVHHQK^LVFFAEDVGSNK^GAIIGL-OH
Peptide H-DAEFRHDSGYEVHHQK^LVFFAEDVGSNK^GAIIGL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-Asp-Phe-OH
CAS:H-Asp-Phe-OH is a diagnostic agent that contains the amino acid aspartame and a hydroxyl group. It is hydrolyzed in the body to form aspartic acid, phenylalanine, and methanol. The methyl ester of H-Asp-Phe-OH is hydrochloride. This compound has been used to study locomotor activity in mice and rats. Aspartame has also been shown to be an inhibitor of certain enzymes, such as fatty acid synthase, which is associated with human pathogens. The lc-ms/ms method has been used to detect H-Asp-Phe-OH metabolites in human serum samples. In addition, this compound can be used for the diagnosis of diseases such as diabetes mellitus type 2 and Alzheimer’s disease by measuring uptake into cells at enzyme activities.
Fórmula:C13H16N2O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:280.28 g/molH-GAYPLSIEPIGV^R-OH
Peptide H-GAYPLSIEPIGV^R-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Z-Val-Ala-Asn-AMC
CAS:Z-Val-Ala-Asn-AMC is a reagent that is used in the synthesis of complex compounds. It is a versatile building block, which can be used to make a wide range of compounds. It has been shown that Z-Val-Ala-Asn-AMC is an excellent reaction component for the synthesis of several important bioactive compounds.Fórmula:C30H35N5O8Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:593.63 g/molHeat shock protein (3-13)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C57H94N18O20Peso molecular:1,351.49 g/molH-Orn-Hyp-Myristoil2 · 2HCl
Please enquire for more information about H-Orn-Hyp-Myristoil2 · 2HCl including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C38H78N4O4Cl2Pureza:Min. 95%Peso molecular:723.96 g/molH-ASMTNMEL^M-OH
Peptide H-ASMTNMEL^M-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-Ala-Ala-OH
CAS:Ac-Ala-Ala-OH is a compound that has been shown to bind to the receptor molecule, and is stable in the presence of proton. It also forms stable complexes with amide and teicoplanin. Ac-Ala-Ala-OH has a carbonyl group, which can be detected by magnetic resonance spectroscopy (MRS) at 1.8 ppm. The compound also has an nmr spectrum in which it can be seen that the trifluoroacetic acid does not affect the binding experiments. Ac-Ala-Ala-OH is used for binding experiments because it binds specifically to the receptor molecule and has a number of other properties that make it useful for research purposes.Fórmula:C8H14N2O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:202.21 g/molMal-RSQSRSRYYRQRQRSRRRRRRS-NH2
Peptide Mal-RSQSRSRYYRQRQRSRRRRRRS-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.IDE Inhibitor 6bK
The enzyme inhibitor 6bK is a peptide that inhibits the activity of insulin. It has been shown to inhibit the synthesis of protein, DNA, and RNA in cells. This inhibition has led to cell death by apoptosis. 6bK has also been shown to have anti-inflammatory effects.
Fórmula:C41H55N7O7Pureza:Min. 95%Peso molecular:757.94 g/molH-Val-Trp-OH
CAS:H-Val-Trp-OH is a noncompetitive inhibitor of the enzyme tyrosinase, which plays a role in melanin production. It also has radical scavenging activities and can inhibit the activity of other enzymes such as glucose 6-phosphate dehydrogenase and acetylcholinesterase. The compound is stable in aqueous solution and can be used to study the effects of H-Val-Trp-OH on wheat germ cells. It is composed of an amino acid sequence that resembles tyrosine, with a carboxylate group attached to the hydroxyl group at position 3. H-Val-Trp-OH is most active against tyrosinase when it is in its activated form, but it can also act as an inhibitor when it is not activated. The compound inhibits the activity of tyrosinase by binding to its active site and blocking the binding or catalysis of substrate molecules. This inhibition occurs through competitive interactions withFórmula:C16H21N3O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:303.36 g/molSIVmac239 - 23
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,777 g/molH-GGEEEEYFELVKKKK-OH
CAS:JAK3tide is a synthetic peptide, which is a highly specific substrate. Derived from comprehensive biochemical studies, it targets the catalytic activity of the Janus kinase 3 (JAK3) enzyme. JAK3tide's mode of action involves being phosphorylated by JAK3, an essential kinase involved in the signaling pathways of certain cytokines, making it a vital tool for assaying JAK3 activity.When used in in vitro kinase assays, it enables precise quantification of JAK3's enzymatic activity, which is pivotal for understanding pathway dynamics involved in immune responses. Its application extends to research areas focused on elucidating the mechanisms of immune signaling pathways and for the development of inhibitors as potential therapeutic agents in immunological disorders. JAK3tide provides a robust framework for scientists aiming to dissect the nuanced interactions within the JAK-STAT pathway and identify novel therapeutic targets, particularly in conditions where JAK3 is dysregulated.Fórmula:C82H129N19O27Peso molecular:1,813.02 g/molH-SAPATGGVK^-OH
Peptide H-SAPATGGVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-NTQPIMDTDGSYFVYSK^-OH
Peptide H-NTQPIMDTDGSYFVYSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-Glu{Glu[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2}2
H-Glu{Glu[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2}2 is a tetrameric peptide that has been shown to have a broad spectrum of biological activity. This peptide may be involved in the regulation of cell growth and proliferation, which may contribute to its anti-inflammatory effects. H-Glu{Glu[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2}2 also inhibits the production of nitric oxide, which may contribute to its antimicrobial properties against bacteria and fungi.Fórmula:C123H179N39O34Pureza:Min. 95%Peso molecular:2,748.04 g/molH-STALQLIQR^-OH
Peptide H-STALQLIQR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-LGEYGFQNAL^-OH
Peptide H-LGEYGFQNAL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-MASMTGGQQMGR^-OH
Peptide H-MASMTGGQQMGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Fmoc-Ala-Wang Resin (100-200 mesh) 1% DVB
This is a vivitide catalogue product. Please send your vivitide product enquiry to sales@vivitide.com for an up-to-date price and availability.Pureza:Min. 95%H-ALPNNTSSSPQPK^-OH
Peptide H-ALPNNTSSSPQPK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Ac-Arg-[Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys]-NH2
Ac-Arg-[Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys]-NH2 is a peptide that has antagonist activity against melanin, the hormone receptor. This peptide can be used to treat skin pigmentation disorders such as vitiligo, which is an autoimmune disorder in which the melanocytes are destroyed. Ac-Arg-[Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys]-NH2 is also an aminovaleric acid derivative, which can inhibit the production of aminovaleric acid and related compounds.Fórmula:C49H82N16O11S3Pureza:Min. 95%Peso molecular:971.22 g/molDynorphin A (1-11), porcine
Catalogue peptide; min. 95% purityFórmula:C63H103N21O13Peso molecular:1,362.66 g/molH-VGEVIVTK^-OH
Peptide H-VGEVIVTK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-FYGAEIVSALEYLHSR^-OH
Peptide H-FYGAEIVSALEYLHSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Rhodopsin Epitope Tag
ID4 is a highly versatile epitope tag. The peptide sequence is highly specific to rhodopsin and related photoreceptor proteins, meaning when used with monoclonal antibodies off-target signals are virtually non-existent. ID4 is also devoid of charged residues therefore reducing nonspecific ionic interactions. Monoclonal antibodies also bind to ID4 with high affinity therefore there is less need for inserting multiple copies of ID4.Peso molecular:902.4 g/molIndolicidin
Peptide Indolicidin is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fórmula:C100H132N26O13Peso molecular:1,906.33 g/molPolylysine
Peptide Polylysine is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Fórmula:C60H122N20O11Peso molecular:1,299.77 g/molAc-KKRYSREFLLGF-NH2
Peptide Ac-KKRYSREFLLGF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.SIVmac239 - 102
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,777.1 g/molMotilin (1-10)
Residues 1-10 of the gastrointestinal hormone motilin, secreted from endocrine cells in the small intestines, mainly from the jejunum and duodenum, in response to the fasting, drinking water or the mechanical stimulus of eating.Peso molecular:1,184.6 g/molNeurokinin A (Substance K)
Neurokinin A (NKA) is a member of the classical tachykinins family of peptides which also includes substance P and neurokinin B. These peptides are primarily found in the nervous system where they act as neurotransmitters and neuromodulators. They also play key roles in neuronal inflammation, and high levels of NKA have been linked to poor prognosis of some tumours.The tachykinin peptides are characterised by a common C-terminal sequence, Phe-X-Gly-Leu-Met-NH2, where X represents either an aromatic (Phe, Tyr) or a branched aliphatic (Val, Ile) amino acid.This C-terminal region is thought to be responsible for activating the receptor. The divergent N-terminal region is thought to play a role in determining the receptor subtype selectivity. NKA binds preferentially to the NK2 receptor.Peso molecular:1,132.6 g/molPhosphorylated CHKtide
CHKtide is a synthetic peptide substrate for checkpoint-kinase-1 and 2 (CHK1/CHK2) as well as salt-inducible kinase (SIKs) for use in kinase assays. CHKtide has been derived from CDC25C which is phosphorylated by CHK1/CHK2 in one of the DNA repair pathways. SIKs are serine/threonine kinases that are part of a complex network that regulate sodium homeostasis and blood pressure.The serine residue at position 5 of this peptide has been phosphorylated.
Cor e Forma:PowderPeso molecular:2,779.4 g/molUDP-β-L-Rhamnose
CAS:UDP-β-L-Rhamnose is a pentose sugar that is used as a research tool and an activator. It has been shown to be an inhibitor of ion channels and protein interactions, as well as a ligand for certain receptors. This compound has high purity and can be used in the study of cell biology, pharmacology, and immunology.
Fórmula:C15H24N2O16P2Pureza:Min. 95%Peso molecular:550.3 g/molH-GPSSVEDIK^-OH
Peptide H-GPSSVEDIK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
IDR-1
As an antimicrobial peptide (AMP), IDR-1 acts indirectly on pathogenic bacterial infections. IDR-1 is proposed to function by upregulating monocyte cytokines (interleukins) while also reducing a pro-inflammatory cytokine. IDR-1 has been tested for its ability to aid against the rise of multi-drug resistant bacteria. In mouse models, IDR-1 is protective against Gram-positive and Gram-negative pathogens. Supply of IDR-1 can also attenuate methicillin-resistant staphylococcus aureus (MRSA)-induced pneumonia. The IDR-1 sequence is being studied as a template to hopefully generate more potent synthetic versions.Peso molecular:1,391.74 g/mol[5-FAM]-C7
Selective peptide ligand for FRalpha, demonstrating specific binding to FRalpha expression cells and tumour targeting ability in vivo. It contains 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.Peso molecular:1,732.7 g/molCMVpp65 - 73 (HIMLDVAFTSHEHFG)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,741 g/mol5TAMRA-RRRRRRRRRC-NH2
Peptide 5TAMRA-RRRRRRRRRC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Galanin Mouse, Rat
Galanin (mouse, rat) is 29 amino acids, 1 less than human galanin. Galanin is a widely distributed neuropeptide in the central nervous, peripheral, and endocrine systems. Galanin interacts with 3 receptor subtypes, GalR1-3. These G protein-coupled receptors are inserted into the plasma membrane. Galanin has a role in energy homeostasis. Central injections of galanin to the amygdala lead to food intake in rats.Galanin has been shown to inhibit glutamate release from the hippocampus. Glutamate has an excitatory effect in the mechanisms of epileptic seizures- therefore, galanin is considered a possible anticonvulsant. Galanin receptor agonists with anticonvulsant properties have been developed to help seizures. Galanin has also helped provide evidence of neuronal plasticity and degradation. Galanin has been used extensively for administration to animals in vivo including rats and mice to better understand its role and help treat appetite disorders.Cor e Forma:PowderPeso molecular:3,162.6 g/molANP (7-20)
ANP (7-20) is derived from the atrial natriuretic peptide (ANP) which is a cardiac hormone involved in maintaining cardio-renal homeostasis. This occurs through the activation of the guanylyl cyclase-coupled receptor, resulting in the increased concentration of cyclic guanylate monophosphate. Moreover its function in the processes of anti-proliferation and anti-angiogenesis allow it to take part in the cardiovascular remodelling process.ANP is a member of the natriuretic peptide family and it is encoded by the NPPA gene, located on chromosome 1. Once synthesized from the 151 amino acid pre-prohormone into its biologically active form, ANP is secreted by the atrial cardiomyocytes in the circulating forms: ANP (1-98) and ANP (99-126). This synthesis process involves the signal peptide being removed from the pre-prohormone resulting in proANP (1-126) which is converted into the circulating forms by the type II transmembrane serine protease Corin.Cor e Forma:PowderPeso molecular:1,453.7 g/molHistone H3 (1-20) K4Me3, K9Ac, pS10-GG-[Lys(5-FAM)]
Histone 3 (H3) is one of the four core histones (H2A, H2B, H3 and H4) fundamental in compacting eukaryotic DNA into the nucleosome. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core. Both H4 and H3 are highly conserved and perform roles in binding to segments of DNA which enter and leave the nucleosome and in chromatin formation. Similar to the other core histone, H3 has a globular domain and a flexible N-terminal domain, 'histone tail' which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination. The transcriptional activation or silencing of the chromatin is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes which target histone proteins. Both processes function to alter the positioning of the nucleosome, allowing the DNA it to be either available or inaccessible to the transcription machinery.The lysine at position 4 of this peptide has been tri-methylated and it is implicated in studies that this modification may remodel the chromatin so that it is more accessible to transcription factors, which may ultimately increase the level of gene expression. The lysine at position 9 has been acetylated, which neutralizes the positive charge on the amino acid, loosening the chromatin structure. This alteration to the accessibility of chromatin promotes the initiation of transcription. Moreover, the serine at position 10 has been phosphorylated, and studies have suggested that this may induce chromatin condensation, and subsequently repress transcription and gene expression.This peptide contains a C-terminal GGK linker labelled with 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag. This peptide also has an uncharged C-terminal amide.Peso molecular:2,946.5 g/molHXB2 gag NO-90
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,597.9 g/molPAF26
PAF26 is a cell penetrating antimicrobial peptide (CP-AMP) with strong activity against fungi that cause postharvest decay in fruits, such as strains of Penicillium italicum, Penicillium digitatum, and Botrytis cinerea and is also active against Fusarium oxysporum.PAF26 has reduced toxicity to Escherichia coli and Saccharomyces cerevisiae, demonstrating selectivity towards certain filamentous fungi. PAF26 is endocytically internalized at low fungicidal concentrations and accumulates in vacuoles before being actively transported into the cytoplasm where it exerts its antifungal activity. PAF26 is not lytic or cytotoxic to human cells.Cor e Forma:PowderPeso molecular:990.6 g/molNBD peptide / NF-κB blocker (cell permeable)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Fórmula:C121H202N48O32Peso molecular:2,841.2 g/molTAT - GluR23Y
TAT-GluR23Y is a cell penetrating peptide that inhibits phosphorylation of AMPA receptor endocytosis.Recent studies have shown that AMPA receptor endocytosis, which is a cellular mechanism underlying the formation of LTD, plays a critical role in facilitating initial extinction of learned fear. Tat-Glur23Y can block regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus.Peso molecular:2,632.4 g/molH-AL^PAPIEK-OH
Peptide H-AL^PAPIEK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
TAT-CN21
TatCN21 is an inhibitor peptide for the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. TatCN21 blocks both autonomous and stimulated CaMKII activity with high selectivity. CaMKII is highly expressed in brain tissue where it regulates several processes including: neurotransmitter synthesis/release, neuronal plasticity- excitability and calcium homeostasis. Glutamate clearance by astrocytes is an essential part of normal excitatory neurotransmission, and accumulation of glutamate in the central nervous system is associated with many neurodegenerative disorders. CaMKII regulates glutamate homeostasis: CaMKII inhibition results in diminished glutamate uptake, dysregulated calcium homeostasis, release of the gliotransmitter ATP and compromise neuronal survival. Loss of CaMKII signalling may be an important factor in excitotoxicity. Peptide was obtained by linking the 11 amino acid human HIV Tat transporter to a 21 amino acid sequence corresponding to the CN21.
Cor e Forma:PowderPeso molecular:3,986.4 g/molH-EDSILAVR^-OH
Peptide H-EDSILAVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-TPSLPTPPTR-NH2
Peptide Ac-TPSLPTPPTR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
TAT-AKAP79 (326-336) scrambled amide
The activation of transient receptor potential cation channel subfamily V member 1 (TRPV1) is believed to play a role in hyperalgesia, asthma and hypertension. TRPV1 is important for neuronal pain detection as well as the detection of heat, capsaicin, protons and the neurotransmitter anandamide.- The scaffold protein AKAP79 targets kinases to phosphorylate TRPV1, however it has been shown that inflammatory intermediates prostaglandin-E2 or bradykinin can activate these kinases creating a route for inflammation to cause hyperalgesia.This product is composed of the TRPV1 interacting residues of AKAP79 reordered into a scrambled sequence and conjugated to the cell penetrating TAT domain at the N-terminus. The scrambled peptide was shown in vivo to have no effect on TRPV1 algesia and thus is a vital control for research work. This product is a vital tool for research into suitable TRPV1 antagonists. The scrambled-TAT peptide is available for purchase in both an acid and amide form, this is the C-terminal amide form.
Peso molecular:2,877.6 g/molCompstatin
The cyclic tridecapeptide Compstatin, binds to and selectively inhibits the interaction between C3 and convertase, hence preventing the formation of C3a and C3b and activation of the complement system. Compstatin has the ability to form β-turns and hydrophobic clusters which are crucial for its inhibitory properties. When binding between C3 MG4 and MG5 domains, located within the MG-ring of the β-chain, Compstatin undergos a conformational change which is believed to prevent C3 from binding to C3 convertase through steric hindrance. Consequently the complement cascade is inhibited.The complement cascade is an important feature of the immune system. C3b, produced from the interaction of C3 and C3 convertase, binds to pathogens and somatic cells and signals for their removal from the body. However the increased activation of the complement system can result in diseases, associated with Alzheimers, strokes, heart attacks and autoimmune diseases. Therefore Compstatin can be used as a therapeutic agent within medicine.Cor e Forma:PowderPeso molecular:1,549.7 g/molAc-CKNTPDPDDLFSDI-OH
Peptide Ac-CKNTPDPDDLFSDI-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
SIVmac239 - 91
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,582.9 g/molHistone H3 (1-34)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Fórmula:C144H260N54O44Peso molecular:3,451.98 g/molNeuropeptide S human
Neuropeptide S (NPS) is a neuropeptide found in mammalian brains, primarily in neurons in the lateral parabrachial nucleus, the peri-locus coeruleus and the principle sensory 5 nucleus of the trigeminus. NPS in involved in several neuroendocrine, behavioural and inflammatory responses, including: reducing anxiety in mice- suppressing appetite and inducing wakefulness and hyperactivity. NPS treatment can be used to improve fear extinction in mice and limit fear memory retrieval after fear reduction training, thus making it an interesting target for treatment of post-traumatic stress disorder. NPS exerts its actions by binding to a G-protein coupled receptor, NPSR.Peso molecular:2,186.1 g/molsurvivin (baculoviral IAP repeat-containing protein 5) (21-28)
Survivin is an intracellular tumour-associated antigen that is part of the inhibitor of apoptosis (IAP) family. Survivin expression increases as cells age but becomes over-expressed in cancer cells. Expression is also important during embryonic development and tissue regeneration. With roles in aging, apoptosis, and cancer, there is considerable interest in understanding the function of Survivin. Survivin expression is regulated by TGF-β and increased following intestinal inflammation during the healing process.The high expression of Survivin in cancer cells has led to the search for a vaccine that induces epitope-specific CD8+ T cells. The epitope TFKNWPFL restricted to H-2 Db was identified using prediction algorithms and MHC class I binding assays. The epitope was delivered to mice by intradermal electroporation (EP). The Survivin epitope induced a CD8+ cytotoxic T lymphocyte (CTL) response as shown by IFN-staining- they also showed an activated effector phenotype as CD44 and CD107 were upregulated. The Survivin vaccine was able to confer protection against melanoma in mice and suppress angiogenesis. This Survivin epitope could be a vital step in creating a human vaccine that generates CD8 CTLs with specific functional cytotoxic activity against tumour cells.The sequence provided here aligns to residues 21-28 of the Survivin epitope, the initial residue of the epitope has been omitted as it is not conserved between mice and human sequences.Peso molecular:1,051.5 g/molH-LQDAEIAR^-OH
Peptide H-LQDAEIAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.MART-1 (26-35) (human)
CAS:Native Melan-A (26-35) decapeptide derives from the melanocyte lineage-specific protein Melan-A/MART-1, which is expressed in almost 75-100% of primary and metastatic melanomas. The region 26-35 of Melan-A protein acts as an antigenic peptide that is recognized by CD8+ tumor-reactive cytolytic T lymphocytes (CTLs) for designing antigen-specific cancer vaccines1. It has been shown that CD8+ Melan-A-specific CTLs isolated from melanoma patients efficiently lyse the Melan-A-expressing HLA-A*0201+ melanoma cell line. However, CTLs preferentially recognize the Melan-A (26-35) peptide as compared with the Melan-A (27-35) peptide. Moreover, the Melan-A (26-35) A27L analog (ELAGIGILTV) has a higher binding affinity to HLA-A*0201 than the native Melan-A (26-35) peptide (EAAGIGILTV), and consequently displays more potent antigenicity and immunogenicity. It has been reported that the concentration of Melan-A (26-35) A27L analog required to obtain 50% of maximal antigenic activity (EC50) is 0.01nM, whereas that of the native Melan-A (26-35) peptide is 0.25nM1. Therefore, the relative activity of Melan-A (26-35) A27L analog is 25 fold higher than that of the native Melan-A (26-35) peptide. Furthermore, functional competition assay has shown that the concentration of Melan-A (26-35) A27L analog required to achieve 50% inhibition (IC50) of tumor lysis is 2nM, which is 10 fold lower than that of the native Melan-A (26-35) peptide. Regarding peptide stability in human serum, the half-lifes (t1/2) of the native Melan-A (26-35) peptide and the A27L analog are quite similar (45 and 40min, respectively) as measured by HPLC-ESI-MS, but much higher than that of the Melan-A (27-35) nonapeptide (5min).Fórmula:C42H74N10O14Peso molecular:943.11 g/molH-ELTIGSK^-OH
Peptide H-ELTIGSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Peptide YY (Dog, Mouse, Porcine, Rat, 3-36)
CAS:PYY (3-36), a Y2 receptor agonist, is released from the body's gastrointestinal tract in proportion to caloric intake. It has been shown that peripheral injection of PYY (3-36) in rats inhibited food intake and reduced weight gain. In addition, infusion of PYY (3-36) in humans significantly decreased appetite and reduced food intake by 33% over 24h, which suggests that PYY (3-36) has a role in 'longer term' regulation of food intake. Thus, the PYY (3-36) may represent a lead compound for the development of drugs for the treatment of obesity. This product is available as an Acetate salt.Fórmula:C176H272N52O54Pureza:Min. 95%Peso molecular:3,980.45 g/molSARS-CoV-2 Nucleoprotein (353-370)
The coronavirus (CoV) nucleoprotein is the major component of CoV structural proteins. Also known as the nucleocapsid protein, it is an abundant RNA-binding protein critical for viral genome packaging. These factors make nucleoprotein a good target for developing new antiviral drugs. In addition, the identification of epitopes within the nucleoprotein sequence can help design more effective SARS-CoV-2 vaccines.Models have predicted epitopes exhibiting antigenicity, stability and interactions with MHC class-I and class-II molecules. Nucleoprotein (353-370) is an epitope candidate with various HLA restrictions. This epitope can be used to better vaccine design for more durable CD4+ and CD8+ T cell responses for long-lasting immunity.Peso molecular:2,111.1 g/molGLP-1 (1-37)
CAS:Glucagon-like peptide (GLP) 1 is a post-translationally modified version of proglucagon. GLP-1 (1-37) is a naturally produced analog of GLP-1. Unlike truncated GLP-1, GLP-1 (1-37) does not alter food intake in rat models or pancreatic insulin secretion. GLP-1 (1-37) can induce insulin production in developing adult intestinal cells via upregulation of the ngn3 gene and its downstream targets. This can restore glucose homeostasis when implanted into diabetic mice. GLP-1 (1-37) may offer a future treatment for diabetes mellitus. GLP-1 (1-37) can also inhibit chemokine-induced migration of human CD4-positive lymphocytes, an early step in atherogenesis. This raises the possibility that GLP-1 (1-37) is part of a novel mechanism to modulate vascular disease.Peso molecular:4,169.54 g/molHyp-Gly dipeptide
A hydroxyproline glycine peptide in acid form. This peptide is a substrate for prolyl dipeptidase. Ingestion of the Hyp-Gly dipeptide can improve skin conditions. Hyp-Gly ingestion improves facial skin moisture and elasticity and reduces facial aging. Additionally, Hyp-Gly enhances fibroblast proliferation.Peso molecular:188.1 g/molHXB2 gag NO-89/aa353 - 367
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,492.8 g/molH-LPPYLFT-OMe
Peptide H-LPPYLFT-OMe is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Ghrelin Rat, Mouse
Ghrelin is involved in several physiological processes, including feeding and lipid accumulation, stress response, anxiety, cardiac performance, immunity and inflammation, taste sensation, reward-seeking behaviour, regulation of glucose metabolism and thermogenesis, memory, motivation and learning.Ghrelin is a peptide hormone that typically has a serine at the third residue and relies on modification with a fatty acid to give ghrelin its functional activity. In its modified form, ghrelin is an endogenous ligand for the pituitary gland's growth hormone receptor (GHS-R) and stimulates growth hormone release. Rat/mouse ghrelin differs from the human form at positions 11 and 12 (RV) in rats to (KA) in humans.Ghrelin acts on the hypothalamic arcuate nucleus as an orexigenic agent to stimulate appetite. Ghrelin is produced in the stomach as a precursor peptide preproghrelin, cleaved to ghrelin. Ghrelin circulates in the blood and can cross the blood-brain barrier. Levels of ghrelin respond to fasting conditions and allow signals about the energy status to be transmitted from the peripheral organs to the central nervous system to maintain energy homeostasis.Ghrelin is a valuable target for treating conditions such as anorexia, cachexia, sarcopenia, cardiopathy, neurodegenerative disorders, renal and pulmonary disease, gastrointestinal disorders, inflammatory disorders and metabolic syndrome.Cor e Forma:PowderPeso molecular:3,314.8 g/molTransportan
Transportan is an amphipathic 27 amino acid peptide that was generated from 12 functional amino acids of galanin and 14 amino acids of mastoparan connected via a lysine residue. Transportan has been functionally characterised as a cell penetrating peptide (CPP) that does not appear to be mediated by endocytosis. All cell types tested were permeated by transportan, initially localising to the outer membrane it then travels to cytoplasmic membrane structures and eventually perfuses to the nucleoli. This CPP has been used for numerous applications and assays to great effect including indirect immunofluorescence and drug delivery.TP reveals some characteristic features of both galanin and mastoparan since it inhibits the binding of galanin to GALR-1 receptor as well as modulates the activity of G proteins due to the inhibition of GTPase activity.Cor e Forma:PowderPeso molecular:2,180.4 g/molFmoc-Cys-OH
Peptide Fmoc-Cys-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-ALLFIPR^-OH
Peptide H-ALLFIPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-VNLLSAIK^-OH
Peptide H-VNLLSAIK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Z-Leu-Leu-Leu-H (aldehyde)
CAS:Z-Leu-Leu-Leu-H (aldehyde) is an inhibitor that binds to a receptor and prevents the binding of a ligand. This competitive inhibition is reversible and can be used as a research tool to study protein interactions. The high purity of this product makes it ideal for use in pharmacology, cell biology, and life science research.Fórmula:C26H41N3O5Pureza:Min. 95%Peso molecular:475.62 g/molKisspeptin 234
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Fórmula:C63H78N18O13Peso molecular:1,295.42 g/molH-ATFQTPDFIVPLTDLR^-OH
Peptide H-ATFQTPDFIVPLTDLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.[5-FAM]-(RFR)4XB
(RXR)4XB is a cationic membrane-penetrating peptide and is effective in delivering phosphorodiamidate morpholino oligonucleotides (PMOs) into eukaryotic cells such as Escherichia coli. It contains 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.Peso molecular:2,396.3 g/molNangibotide
Nangibotide, also referred as LR12, is an antagonist of triggering receptor expressed on myeloid cells (TREM)-1, and was derived from residues 94 to 105 of TREM-like transcript-1 (TLT-1).TREM-1 plays a crucial role in the onset of sepsis by amplifying the host immune response. TLT-1- and TLT-1-derived peptides therefore exhibit anti-inflammatory properties by dampening TREM-1 signalling. LR12 blocks TREM-1 by binding to the TREM-1 ligand and provides protective effects during sepsis such as inhibiting hyper-responsiveness, organ damage, and death, without causing deleterious effects. The protective effects of modulating TREM-1 signalling are also evident in other models of inflammation such as: pancreatitis- haemorrhagic shock- inflammatory bowel diseases and inflammatory arthritis.Cor e Forma:PowderPeso molecular:1,342.5 g/molXenin
Leptin and melanocortin are well characterised for their roles in energy balance and the regulation of feeding. However, xenin was subsequently isolated from human gastric mucosa and identified as a gastrointestinal peptide hormone. Evidence shows xenin plasma levels rise after meals while administration of xenin leads to feelings of satiation. Unfortunately, the mechanism of xenin regulation on food uptake is still not fully understood. Work has shown xenin negatively effects food intake by a dose dependent manner, the hypothalamus seems to have a key role in this. Furthermore, the signally pathways activated by xenin is independent of those used by leptin or melanocortins. Further work with xenin could provide vital answers to the inhibitory mechanism of this gastrointestinal hormone. It would provide more data to help tackle the ongoing obesity crisis and rise in the number of diabetic patients.Cor e Forma:PowderPeso molecular:2,969.7 g/molAc-TGGKAPR-NH2
Peptide Ac-TGGKAPR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Ac-AKFVAAWTLKA-NH2
Peptide Ac-AKFVAAWTLKA-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Cyclo(Arg-Gly-Asp-D-Phe-Cys)
CAS:Cyclo(Arg-Gly-Asp-D-Phe-Cys) is a cyclic peptide that can form stable complexes with platinum. It has been shown to have anticancer activity against cervical cancer cells in tissue culture. Cyclo(Arg-Gly-Asp-D-Phe-Cys) binds to the integrin receptor on the surface of cancer cells, which leads to changes in redox potential, leading to cell death by apoptosis or necrosis. Cyclo(Arg-Gly-Asp-D-Phe-Cys) also has pharmacological properties that make it a good candidate for treatment of cancer.
Fórmula:C24H34N8O7SPureza:Min. 95%Peso molecular:578.65 g/molXL 13m
Inhibits the epigenetic reader YEATS domain of the Eleven-nineteen leukemia (ENL) protein and perturbs the recruitment of ENL onto chromatin. Induces downregulation of a set of genes that are essential for leukemogenesis and leukaemia maintenance.Peso molecular:509.3 g/molAntennapedia peptide
Identification of cell penetrating conjugates has aided numerous areas of scientific development. The Drosophila transcription factor Antennapedia contains a homeodomain that can be internalised by cells to the cytoplasm and to the nucleus in a receptor-independent mechanism. The key residues for internalisation have been sequenced (RQIKIWFQNRRMKWKK), named penetratin, and used in several studies to aid entry of fusion proteins into cells.The full 60 amino acid homeodomain was fused to a T cell epitope of the influenza nucleoprotein and successfully internalised into T cells for presentation. The CPP, penetratin, was fused to a ligand for Grb-2 resulting in inhibition of downstream Grb-2 signalling events.- Penetratin has also been used in vivo to prime cytotoxic T lymphocytes by conjugating short antigenic peptides to the CPP. Penetratin is provided here as a C-terminal acid but is also available in amide form.Peso molecular:2,246.73 g/mol
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![Histone H3 (1-20) K4Me3, K9Ac, pS10-GG-[Lys(5-FAM)]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FCRB1101265.webp&w=3840&q=75)
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