Peptídeos

RGD peptide with a Biotin Reporting Tag and PEG Spacers for more efficient binding to Lipid surfaces. This product may require further derivatization before use. The one letter sequence for this peptide is: c(RGDfK(Biotin-PEG-PEG)) where PEG = 8-Amino-3,6-Dioxaoctanoic Acid.

MOG (92-106) is a peptide that is derived from myelin basic protein. It has been shown to be immunogenic and can induce the production of antibodies in animals. MOG (92-106) also induces demyelination in mice.

DOTA-Glu-[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2 is a trifunctional cyclic peptide that can be derivatized with various groups such as radiolabels. It has been shown to have strong affinity for the integrin receptor and can be used for targeting of tumors. DOTA-Glu-[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2 has also been found to inhibit cell proliferation and induce apoptosis in tumor cells.

Lysostaphin is a bacteriolytic enzyme that is produced by the bacteria Staphylococcus simulans. It cleaves the cross-linked pentaglycine bridges in bacterial cell walls which are essential for their structural integrity. Lysostaphin displays a broad spectrum of activity against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). The recombinant form of lysostaphin has been expressed in E. coli and can be used to produce large quantities of lysostaphin for therapeutic use. Expression of lysostaphin in E. coli has also allowed for the production of other polypeptides with antimicrobial properties, such as the clostridial bacteriocins and staphylokinase.

Suc-Ala-Pro-Ala-pNA is a synthetic substrate that inhibits serine proteases. It has been shown to inhibit thrombin, trypsin, and chymotrypsin at low concentrations. Suc-Ala-Pro-Ala-pNA is used as an anticoagulant in rat neutrophils and it has also been found to have chemotactic activity for neutrophils at high concentrations. The substrate was also found to be an efficient method of detecting the presence of protease activity in plant physiology experiments. In addition to its use as a proteinase inhibitor, Suc-Ala-Pro-Ala-pNA can also be used as an antiplatelet agent.

MOCA-Pro-Leu-Gly is a peptide that can bind to the receptor for the neurotransmitter acetylcholine. It is a competitive inhibitor of acetylcholine and has been shown to have an affinity for the nicotinic acetylcholine receptor (nAChR) in vitro. MOCA-Pro-Leu-Gly has been used as a research tool to study protein interactions, as well as to investigate the function of ion channels and receptors. This peptide also has potential therapeutic uses, such as treating Alzheimer's disease by blocking nicotinic acetylcholine receptors in the brain.

Fmoc-Ile-Wang resin is a polystyrene resin which is used in the synthesis of peptides. It has a high loading capacity, and can be cleaved with hydrofluoric acid. The Fmoc-Ile-Wang resin contains 1% DVB as an acidic scavenger to prevent the formation of side products. The resin is also available in 100-200 mesh size.

A 27 amino acid peptide toxin from the venom of the Chinese red-headed centipede and a potent activator of TRPV1 capsaicin receptor, inducing intense pain. This product is available in the salt form: trifluoroacetate and has the following disulfide Bonds: Cys1-Cys3, Cys2-Cys4.

Viloxazine is a selective inhibitor for norepinephrine uptake over serotonin (5-HT) uptake in rat hypothalamic synaptosomes. It has been studied for its potential uses in treating attention-deficit hyperactivity disorder (ADHD) and depression.Viloxazine hydrochloride is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

IL-2 is a cytokine that regulates the immune system. It is a protein that is produced by T lymphocytes and natural killer cells, and stimulates the production of other white blood cells. IL-2 has two receptor chains: an alpha chain that binds to IL-2 and a beta chain that binds to IL-2 with high affinity. The receptor chains are encoded by genes in the human major histocompatibility complex (MHC) on chromosome 6. IL-2 has been shown to be an activator of ion channels and ligand for antibody molecules. It also has been used as a research tool in cell biology and as an inhibitor for cancer treatment.br>br> IL 2 Human is a recombinant form of Interleukin 2, which is a type of immunotherapy that is used to treat cancer patients who have not responded well to chemotherapy or radiation therapy. This form of Interleukin 2 is purified from E. coli bacteria, which means it does

Boc-L-Glutamic Acid bis-Propargyl Amide is a building block for Click Chemistry. It is a white solid that is soluble in DMF, DMSO and other organic solvents. This product can be used as a reagent for peptide synthesis and as an intermediate for the synthesis of amino acids. Boc-L-Glutamic Acid bis-Propargyl Amide reacts with dimethylaminoethanol to form the corresponding amide. It has been shown that this product can be used in click chemistry reactions to form amides and ureas.

A human truncated analog of Obestatin, a 23 amino acid gastrointestinal peptide, encoded for by the ghrelin gene and is known to reduce food intake through supressing appetite. This peptide has been found to influence the pancreas, cardiovascular system and adipose tissues as well as the gastrointestinal system. One study showed that when high-fat diet fed rats were given chronic administration of obestatin it prevented the development of non-alcoholic fatty liver disease. Consequently Obestatin has the potential to be used in preventing obesity-related diseases.

H-D-Ala-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin for the synthesis of peptides. It is an amino acid resin with D,L-alanyl side chains, which can be cleaved by hydrochloric acid to release the desired amino acid and trityl resin. This resin is used in peptide synthesis reactions to provide a protecting group for the N-terminal amino acid.

Des-n-Octanoyl-[Ser3]-Ghrelin (Human, 1-18) is a non-acylated analog of Ghrelin (Human, 1-18), amino acids 1-18 of the peptide hormone Ghrelin. This peptide does not contain the unique N-octanoyl group which is linked to Ghrelin's third serine residue covalently and which allows Ghrelin to associate with the growth hormone secretagogue receptor (GHS-R). Through interaction with the GHS-R, Ghrelin can exert its various effects on the body such as stimulating appetite, nutrient sensing, meal initiation and the regulation of insulin resistance, diabetes and obesity. Its wider functions are also associated with glucose homeostasis, energy homeostasis, cardio-protective effects, bone metabolism and its potential to be a target for cancer means that it can be used to develop therapies for a whole spectrum of diseases. This molecule is used as a research tool for studying cell biology and pharmacology.

Fmoc-D-Glu(OtBu)-Wang resin is a solid support for peptide synthesis. It is used to synthesize peptides with the Fmoc or O-benzyl protecting group. The resin has a 1% DVB content and an average particle size of 100-200 mesh.

H-Leu-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin that has been used to synthesize peptides. It can be used as a building block for many other chemical reactions, such as cross-linking and oxidation. This resin is typically used in the synthesis of peptides with an amino acid sequence of H-Leu-2-ClTrt and contains 1% DVB. The resin can be used for the synthesis of small organic molecules, such as antibiotics, with a molecular weight between 500 and 2000 Da.

H-Ala-Phe(para-Fluoro)-Arg-Cha-Cit-Tyr-NH2 is a peptide that has been shown to activate Protease Activated Receptor 1 (PAR1). PAR1 is the receptor for thrombin, which is the enzyme responsible for blood clotting. The peptide was found to be a potent activator of PAR1 in vitro and in vivo. It has also been shown to inhibit the production of angiotensin II, which can lead to hypertension. H-Ala-Phe(para-Fluoro)-Arg-Cha-Cit-Tyr-NH2 is a potential candidate for treating cardiovascular diseases such as hypertension.

Alpha-Neo-Endorphin is a peptide that belongs to the group of opioid peptides. It is a potent activator of opioid receptors and has been used as a research tool in cell biology to study the function of opioid receptors. Alpha-Neo-Endorphin activates these receptors by binding to them, and these opioid receptors are involved in the modulation of pain, epidermal nerve fiber regulation and skin homeostasis. It is further demonstrated the ability to in human keratinocytes, stimulate wound healing. alpha-neoendorphin is derived from prodynorphin when it is proteolytically cleaved. This product is available as a 0.5mg vial and is sourced from Porcine.