Peptídeos
Subcategorias de "Peptídeos"
Foram encontrados 29610 produtos de "Peptídeos"
Ac-RLR-[Rh110]-[D-Pro]
Fluorogenic substrate peptide to assay trypsin-like activity. In its intact state this peptide is non-fluorescent, however when the Rhodamine fluorophore is released upon hydrolysation, fluorescence can be detected. This peptide is therefore a useful tool for analysing trypsin-like enzyme activity.The presence of the D-proline residue on the C terminal of the rhodamine molecule ensures one directional rhodamine cleavage which simplifies fluorescence studies. Rhodamine 110 is a laser grade fluorescent dye with excitation maxima at 496 nm and emission maxima at 522 nm.Peso molecular:894.5 g/molOVA (250-264)
Ovalbumin (OVA) is the primary protein in egg-white, and is involved in initiating food allergies and asthma. It is a highly immunogenic protein and can be used for peptide conjugation in the development of antibodies.OVA (250-264) is a class I (Kb)-restricted peptide epitope of OVA. The ovalbumin fragment is presented by the class I MHC molecule, H-2Kb.Peso molecular:1,718.9 g/molH-TSDLIVLGLPWK^-OH
Peptide H-TSDLIVLGLPWK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-GTFAQLSELHCDK^-OH
Peptide H-GTFAQLSELHCDK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-RQIKIWFQNRRMKWKK-bMPAthioester
Peptide H-RQIKIWFQNRRMKWKK-bMPAthioester is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Insulysin FRET substrate [Mca]/[Dnp]
The Insulysin FRET substrate [Mca]/[Dnp] is a synthetic insulysin peptide substrate that contains an N-terminal fluorescent 7-methoxycoumarin (Mca) group and a C-terminal 2, 4-dinitrophenyl (Dnp) quencher. This FRET peptide exhibits internal fluorescence quenching when intact, however hydrolysis of the peptide between the donor/acceptor pair generates fluorescence, enabling the quantitative measure of enzymatic activity.Insulysin, also known as insulin-degrading enzyme (IDE), is a highly conserved zinc metallopeptidase that contains an inverted zincin motif (HXXEH), characteristic of the inverzincin family of proteases. Insulysin functions as a dimer and exhibits allosteric kinetics, whereby small substrate peptides and polyphosphates such as ATP can act as enzyme activators. The endopeptidase cleaves a wide variety of substrates that are diverse in length, structure and sequence and exhibits a preference for basic or bulky hydrophobic residues.Insulysin is ubiquitously expressed and is responsible for insulin catabolism and the degradation of many bioactive peptide substrates including glucagon, TGF-alpha, β-endorphin, dynorphins and atrial natriuretic peptide. Insulysin also selectively degrades amylin and β-amyloid amyloidogenic peptides at multiple sites.Fluorescence Resonance Energy Transfer (FRET) peptides are convenient tools for the study of peptidase specificity and enzymatic activity.Peso molecular:1,422.6 g/molGLK-19
Anti-microbial peptide (AMP) designed using only residues G, L, and K (GLK-19). Active against-Escherichia coli-with higher activity relative to human AMP LL-37 and also weakly active against methicillin-resistant Staphylococcus aureus (MRSA), but not-active against HIV-1. Activity against E. coli with a minimal inhibitory concentration (MIC) at 10 mM.Cor e Forma:PowderPeso molecular:2,104 g/molGrowth hormone releasing protein-2
CAS:Please enquire for more information about Growth hormone releasing protein-2 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C45H55N9O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:817.98 g/molAlloferon 2
Alloferon 2, a member of the Alloferons was extracted from the blood of a Callifora vicina fly who had been experimentally infected. The Alloferons are, bioactive, cationic peptides and can stimulate Natural Killer cell activity and IFN synthesis.Peso molecular:1,127.5 g/molH-LLHGFSFYL^-OH
Peptide H-LLHGFSFYL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.pp89 phosphoprotein fragment [Mouse cytomegalovirus 1]
Cytomegalovirus (CMV) is a prevalent human pathogen of concern in the immunocompromised such as during organ transplant or in AIDs patients- it can potentially be fatal. Due to the commonness of CMV, one strategy being developed is prevention of viral reactivation in immunosuppressed groups. Current antivirals have significant toxicity thus pushing the search for a specific CMV therapy.Murine CMV has been well established as a model for human CMV, including its susceptibility to T cell mediated clearance. The immediate-early protein 1 (IE1) was fragmented and used to find the best IE1 epitope as a vaccine. YPHFMPTNL, provided here, recognized by H-2 Ld-restricted CD8+ T cells was the best epitope of IE1 for T cell recognition. The fragment has been used to successfully generate CD8+ T cell clones specific for the IE1 epitope of murine CMV. This peptide has the potential to further the development of antiviral immunotherapy for CMV and better understand its ability to evade the host immunity.Peso molecular:1,118.5 g/molFeleucin-B01
Feleucin-B01 was recently identified from the skin secretion of the toad Bombina orientalis with a role in preventing the host from bacterial infection. Synthetic feleucin-B01 shows limited antimicrobial activity against a reference Gram-positive bacterium and is ineffective against the Gram-negative and yeast strains. The mode of action of the non-apeptide is lysis of the bacterial membrane resulting in rapid bacterial death. Feleucin-B01 shows a limited role in the secreted host defences which is complemented by the range of alternate antimicrobial peptides (AMP) also excreted. The amphipathic feleucin-B01 sequence is being studied as a template to hopefully generate more potent synthetic versions with a broader range of activity.Peso molecular:931.17 g/molH-IESVLSSSGK^-OH
Peptide H-IESVLSSSGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-LFGPVDSEQLSR^-OH
Peptide H-LFGPVDSEQLSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-LLVP-NH2
Peptide Ac-LLVP-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-GDPGLIGPK^-OH
Peptide H-GDPGLIGPK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Fmoc-Leu-Wang Resin (100-200 mesh) 1% DVB
Fmoc-Leu-Wang Resin is a research tool that can be used to synthesize peptides. It is used as an activator and ligand in the production of antibodies, ion channels, and cell biology. The resin has a high purity and can be used for a variety of purposes such as pharmacology, protein interactions, and peptide synthesis. Fmoc-Leu-Wang Resin has been shown to inhibit the binding of many different proteins to their receptors.Pureza:Min. 95%Ac-CDGPTEIYKLTRKEAQE-OH
Peptide Ac-CDGPTEIYKLTRKEAQE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-GVYYPDK^-OH
Peptide H-GVYYPDK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Melanostatin DM
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C41H58N14O6Peso molecular:843 g/molSIVmac239 - 16
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,509.8 g/molH-TFDEIASGFR^-OH
Peptide H-TFDEIASGFR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Brazzein (1-54)
Brazzein (1-54) is a peptide that belongs to the group of activators. It has been shown to activate potassium channels, which are protein structures that allow potassium ions to pass through the membrane. Brazzein (1-54) also binds to and activates a number of receptors, including nicotinic acetylcholine receptor, serotonin receptor, and vanilloid receptor. This peptide has been shown to inhibit the activity of ion channels in cell culture studies. It has also been shown that brazzein (1-54) is an excellent antibody mimic.Pureza:Min. 95%H-VVNVSSIMSVR^-OH
Peptide H-VVNVSSIMSVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Biotin TAT (48-60)
Biotin TAT (48-60) is a cell penetrating cationic peptide derived from the N-terminus of the Tat protein, which is a trans-activator of the transcription protein present in the human immunodeficiency virus (HIV). The 48-60 region of the TAT peptide is an arginine-rich bascic domain which as a whole has three domains that function to aid HIV through transactivation, DNA binding and nuclear transport. As a cell penetrating peptide (CPP) TAT aids in the cellular uptake of molecules and hence serves a valuable purpose in transduction methods. This property has been demonstrated through its ability of allowing toxins such as the neurotoxin Botulinum neurotoxin Type A, produced by the Clostridium botulinum type A bacteria to penetrate the skin barrier non-invasively.This peptide has a covalently bonded N-terminal Biotin tag that can be used for detection and purification and contains an N-terminal aminohexanoic acid spacer (Ahx).Peso molecular:2,057.2 g/molH-FTISADTSK^-OH
Peptide H-FTISADTSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.VIP (guinea pig)
Vasoactive intestinal peptide (VIP) is a neuropeptide found throughout the body and the central nervous system. VIP is located within cell bodies and nerve endings of the enteric nervous system, brain and pancreas. VIP neurons in the peripheral system fire to regulate blood vessels, and the CNS innervate cerebral vasculature. VIP binds to G protein-coupled receptors VPAC1 and VPAC2. VIP and VPAC2 are detected in circular smooth muscle cells of cerebral arterioles. VIP and VPAC1 are also found in lymphatic tissue. VIP can block inflammation, modify the Th response favouring Th2 and induce regulatory T cells. Overexpression of each receptor has been linked to various cancers.VIP administration leads to pancreatic bicarbonate-rich fluid secretion but not to the same degree stimulated by secretin. VIP stimulates insulin secretion in a glucose-dependent manner and also stimulates glucagon secretion. Studies have found that in morbidly obese patients, VIP levels are lowered and work to slow gastric and duodenal motility but increase gastric emptying. Therefore, decreasing VIP levels in obese patients may increase weight gain by accelerating gastric emptying.VIP has been well studied in pancreatic acini. VIP is a full agonist of amylase secretion and increases cyclic AMP synchronised with an increase in intracellular Ca2+ triggered by stimuli that act through cholecystokinin (CCK) or cholinergic agonists. Most cAMP increases and amylase secretion appears to be mediated via VPAC1.
Peso molecular:3,342.7 g/molAc-ARTKQTARKSTGGKA-NH2
Peptide Ac-ARTKQTARKSTGGKA-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.SARS-CoV-2 Spike (1196-1205)
The SARS-CoV-2 spike protein is present on the outside of the virus particles and can bind to angiotensin-converting enzyme II (ACE2) present on the host cells. The C-terminal receptor binding domain (RBD) of the spike protein binds to the N-terminal peptidase M2 domain of ACE2. This receptor binding results in the internalisation of the virus-receptor complex and is, therefore the mechanism of entry of SARS-CoV-2 into host cells.The spike protein residues SLIDLQELGK (1196-1205) from SARS-CoV-2 have been identified as a T-cell epitope with a predicted HLA restriction. Immune targeting of confirmed epitopes may potentially offer protection against SARS-CoV-2 and help the development of vaccines for long-lasting immunity.Peso molecular:1,114.6 g/molH-R^GFFYTPKT-OH
Peptide H-R^GFFYTPKT-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.[Cys]-Influenza Virus Nucleoprotein (311 - 325)
The Influenza Virus Nucleoprotein (311 - 325) is a component of the viral ribonucleotide complex, derived from the influenza virus and it is involved in viral replication, RNA packing and nuclear trafficking. As a monomer it contains basic residues which allow it to bind to single stranded RNA and through its flexible tail loop it has the ability to form NP oligomers.Furthermore NP is able to support the viral polymerase structurally, through associating with the two subunits PB1 and PB2, and it allows the viral ribonucleotide complex to be transported in and out of the nucleus due to its nuclear localisation and nuclear export signals.During influenza viral replication messenger RNA, viral genome RNA and complementary positive-sense RNA are produced and NP is crucial for this replication.Inhibitors of NP have potential to be used to prevent the influenza virus in humans.
Peso molecular:1,867.9 g/molH-GDSLAYGLR^-OH
Peptide H-GDSLAYGLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-LLSLTYDQK^-OH
Peptide H-LLSLTYDQK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Glutaryl-Gly-Gly-Phe-AMC
CAS:Glutaryl-Gly-Gly-Phe-AMC is a proteolytic peptide which is used in the study of the proteasome. It has been shown to have affinity for the proteasome, and can be used as a monoclonal antibody for both immunohistochemical analysis and two-dimensional electrophoresis. The peptide was sequenced and found to have no homology to any known protein or peptide. Glutaryl-Gly-Gly-Phe-AMC has been shown to bind specifically to β amyloid (Aβ) subunits in cell homogenates and cytosol, as well as nuclei in tissue sections from AD brain. In addition, it has been shown that this peptide can be fluorescently labeled with Alexa Fluor 488 or 594 dye for use in microscopy studies.Fórmula:C28H30N4O8Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:550.56 g/molH-AATVGSLAGQPLQER^-OH
Peptide H-AATVGSLAGQPLQER^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.[5-TAMRA]-LPETGG N-terminal Sortagging
This peptide is recognised and cleaved by the enzyme Sortase A (SrtA) from-Staphylococcus aureus. The catalytic cysteine residue in the active site of SrtA serves as a nucleophile to cleave the peptide bond between threonine and glycine. Cleavage results in the formation of a thioacyl intermediate between the peptide and SrtA. This intermediate is then resolved by the N-terminus of an (oligo)glycine nucleophile, resulting in the creation of a new peptide bond that links the peptide and its fluorescent dye to the incoming nucleophile. This method of protein labelling is known as sortagging.5-Carboxytetramethylrhodamine (5-TAMRA) is a widely used fluorescent dye which excites at 546 nm and emits at 579 nm.Cor e Forma:PowderPeso molecular:983.4 g/molH-LSITGTYDLK^-OH
Peptide H-LSITGTYDLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.PADRE scrambled
SB-peptide offers the scrambled version of PADRE peptide. AAATLWKAAKFVA can be used as a negative control of PADRE peptide studies. SB-peptide offers also PADRE peptide (see section PADRE peptide). PADRE peptide: Pan HLA DR-binding epitope is a universal peptide that activates antigen specific-CD4+ T cells which can be used as an agonist adjuvant in immunotherapeutic vaccine development. Pan HLA DR-binding epitope has been proposed as a carrier epitope suitable for use in the development of synthetic and recombinant vaccines. It has been demonstrated that PADRE may be an universal approach to control tumor cells. Moreover, PADRE is also used in research about an immunosense approach to develop a base for development of vaccines against toxoplasmosis to protect person with HLA-A*03 type. Pan HLA DR-binding epitope can be also used as tool to study the autoreactive T cell response.Fórmula:C65H100N16O14Cor e Forma:PowderPeso molecular:1,347.60 g/molSARS-CoV-2 Spike (999-1007)
The SARS-CoV-2 spike protein is present on the outside of the virus particles and can bind to angiotensin-converting enzyme II (ACE2) present on the host cells. The C-terminal receptor binding domain (RBD) of the spike protein binds to the N-terminal peptidase M2 domain of ACE2. This receptor binding results in the internalisation of the virus-receptor complex and is, therefore the mechanism of entry of SARS-CoV-2 into host cells.The spike protein residues GRLQSLQTY (999-1007) from C have been identified as a T-cell epitope with a predicted HLA restriction. Immune targeting of confirmed epitopes may potentially offer protection against SARS-CoV-2 and help the development of vaccines for long-lasting immunity.Peso molecular:1,064.6 g/molIntegral membrane TGN38A (350-361) acetyl, mouse
Integral membrane protein TGN38 cycles via endosomes between the cell surface and the trans-Golgi network (TGN). Peptides conjugated to the TGN38 sequence inhibit vesicle budding from TGN membranes-in vitro.-This leads to the conclusion that TGN38 is crucial for forming constitutive exocytic vesicles. The trafficking motif SDYQRL in the cytoplasmic domain at the C-terminal contains a critical tyrosine residue (Y). The motif interacts with the medium-chain adaptor subunits of AP-1/2 to allow sorting from the TGN. Mutation of the key tyrosine dramatically reduces binding affinity to AP-1/2. The flanking sequences to the trafficking motif affect the TGN38 localisation of hybrid proteins. Working with the mouse allele TGN38a has helped understand the conservation between mammalian, rat, and mouse TGN protein sequence and function. The TGN38a trafficking motif with flanking regions is provided here in an acid form with N-terminal acetylation.Peso molecular:1,489.8 g/molProinsulin 90-104
The development of type I diabetes occurs when auto-aggressive T cells are not controlled by T regulatory cells and are allowed to destroy pancreatic islet cells. This ultimately eliminates the production of insulin within the body. A more precise understanding of the regulatory T cell's antigen specificity by using antigens can provide significant clinical insights into the development of long-term diabetes. The proinsulin 90-104 fragment was used to test antigen-specific T-cell responses in type I diabetes CD4+ T cells. This peptide has helped show that the development of diabetes is linked to an increase in proinsulin-specific T regulatory cells, which may be regulating the rise in auto-aggressive T cells. Further work with the proinsulin 90-104 peptide could help design novel antigen-specific therapy.
Peso molecular:1,645.7 g/molAc-CERFLGTSEATKL-OH
Peptide Ac-CERFLGTSEATKL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-AVEPQLEDDER^-OH
Peptide H-AVEPQLEDDER^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Suc-LLVY-[Rh110]-[D-Pro]
Fluorogenic substrate peptide of the 20S proteasome. In its intact state this peptide is non-fluorescent, however when Rhodamine fluorophore is released upon hydrolysation, fluorescence can be detected. This peptide is therefore a useful tool for analysing the activity of the 20S proteasome as well as other chymotrypsin-like proteases and calpains. This peptide is also a substrate for chymase, papain, carboxypeptidase Y, proteinase yscE (kexin) and ingensin.The presence of the D-proline residue on the C terminal of the rhodamine molecule ensures one directional rhodamine cleavage which simplifies fluorescence studies. Rhodamine 110 is a laser grade fluorescent dye with excitation maxima at 496 nm and emission maxima at 522 nm.Peso molecular:1,015.5 g/molAlloferon 1
Alloferon 1, a member of the Alloferons is extracted from the blood of experimentally infected Callifora vicina fly and demonstrates both antimicrobial and anti-tumour activity . The Alloferons are bioactive, cationic peptides and exhibit the ability to stimulate Natural Killer cell activity and IFN synthesis. Due to studies investigating the effect Alloferon 1 would have on the central nervous system it was shown that Alloferon 1 had no toxic effects and therefore has the potential to be used as an anti-tumour therapeutic.Cor e Forma:PowderPeso molecular:1,264.6 g/molEndothelin-2 (human, canine)
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C115H160N26O32S4Peso molecular:2,546.97 g/molIGRP Catalytic Subunit-related Protein (206-214)
Peptide corresponding to residues 206-214 of murine islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), the autoantigen targeted by pathogenic CD8+ T cells in non obese diabetic (NOD) mice. Cells that recognize IGRP(206-214) are present in the earliest islet infiltrates of NOD mice and undergo avidity maturation as islet inflammation progresses to overt disease.Peso molecular:1,094.6 g/mol
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