
Peptídeos
Subcategorias de "Peptídeos"
Foram encontrados 29874 produtos de "Peptídeos"
Angiotensin II (1-8)
Angiotensin II (Ang-II) is a key signalling peptide of the renin angiotensin system (RAS) which is involved in regulating blood pressure, cardiovascular function and energy balance. RAS activity is elevated in obesity and is widely studied in relation to lifestyle-related diseases.Ang-II is produced from angiotensinogen (AGT) via the intermediate angiotensin I (Ang-I). AGT is cleaved by the aspartyl-protease, renin, to produce Ang-I, which is then cleaved by the dicarboxyl-peptidase angiotensin converting enzyme (ACE). ACE removes a histidine and a leucine from the C-terminus of Ang-I to form Ang-II.Ang-II exerts its affect by binding to the G-protein-coupled receptors- Ang II type 1 (AT1) and Ang II type 2 (AT2) receptors. Ang-II plays central roles in glucose metabolism and blood pressure. Increased levels of Ang-II have also been associated with Alzheimer's disease, and certain cancers including oesophageal squamous cell carcinoma (ESCC), brain cancers and breast cancers. The effects of Ang-II appear to be supressed by another branch of the RAS- the ACE2/Ang-(1-7)/Mas pathway.Peso molecular:1,045.5 g/molHXB2 gag NO-56/aa221 - 235
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,567.8 g/mol5Fam-RPKPQQFFGLM-OH
Peptide 5Fam-RPKPQQFFGLM-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-LHDFRHQIL^-OH
Peptide H-LHDFRHQIL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.N-formylated PSMalpha3
Pathogenic Staphylococcus aureus strains produce N-formylmethionyl containing peptides. Peptides starting with an N-formylated methionyl group constitute a unique hallmark of bacterial as well as mitochondrial metabolism, and professional phagocytes of our innate immune system recognise this microbial/mitochondrial pattern as a danger signal that guides innate immune cells.All PSMα peptides have the same basic functions and promote virulence through effects on discrete neutrophil functions (i.e. chemotaxis) and by being cytotoxic at higher concentrations. PSMα2 and PSMα3 can both bind to FPR2 and trigger superoxide release in neutrophils at low nanomolar concentrations. In addition, at high nanomolar concentrations they display cytotoxicity selectively on apoptotic neutrophil membranes and this occurs in an FPR2 independent manner.Cor e Forma:PowderPeso molecular:2,633.4 g/molKRREILSRRPSYR-acid
Protein kinases are important drug targets for numerous diseases to try and better evaluate the enzyme specificity, affinity, mode of action and identify possible inhibitors. In vitro assays and synthetic substrates provide valuable data about human kinase activity. CREBtide KRREILSRRPSYR is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein) it is a substrate for protein kinase A (PKA)(Km = 3.9 mM). However, it has also been tested as a substrate for other protein kinases, including cAMP-dependent protein kinase (cAK) and protein kinase C (PKC). Immunoblots and autoradiography have been used for CREBtide KRREILSRRPSYR in vitro kinase analysis.Cor e Forma:PowderPeso molecular:1,716 g/molH-VTSI^Q^D^WV^Q^K^-OH
Peptide H-VTSI^Q^D^WV^Q^K^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Copeptin (rat)
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C183H307N57O61Peso molecular:4,281.8 g/molTyrosine Kinase Peptide 3 [RRLIEDAE-pY-AARG], Acetylated, Amide, Phosphorylated
Catalogue peptide; min. 95% purityFórmula:C66H110N23O24PPeso molecular:1,640.75 g/molH-SELTQQLNALFQDK^-OH
Peptide H-SELTQQLNALFQDK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Cyclo(-D-Leu-D-Pro)
CAS:Cyclo(-D-Leu-D-Pro) is a macrolide that inhibits the growth of bacteria. It binds to the 50S ribosomal subunit and prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. Cyclo(-D-Leu-D-Pro) has been shown to have antibacterial activity against the Gram negative bacterium Vibrio anguillarum. This drug has also been shown to have endophytic properties, as it was isolated from an endophytic fungus found in leaves of Eucalyptus trees. The stereoisomers of cyclo(-D-Leu-D-Pro) have different effects on bacterial cells, with one being more potent than the other.Fórmula:C11H18N2O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:210.27 g/molClickBMVgag7-25
Brome mosaic virus (BMV) Gag peptide (7-25) has been utilised as a cell penetrating peptide (CPP). Translocation across the cell membrane with a cargo molecule varies in effectiveness depending on the CPP. BMV Gag (7-25) has a very high efficiency of internalisation which has been linked to the high percentage of arginine residues present.BMV Gag (7-25) is provided here with a N-terminal alkyne attachment. Two of the most regularly encountered functional groups for click chemistry are azides and alkynes, and the azide-alkyne cycloaddition has become the most popular click reaction. The use of click chemistry with alkyne-BMV Gag (7-25) allows a wide variety of applications particularly for conjugation, modification, and peptide design.Cor e Forma:PowderH-TWLV^PDSR-OH
Peptide H-TWLV^PDSR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
SARS-CoV-2 NSP13 (476-490)
The SARS-CoV-2 non-structural protein 13 (NSP13) has been identified as a target for anti-viral therapeutics due to its highly conserved sequence and is essential for viral replication. NSP13 is part of the helicase superfamily 1B. As an NTPase and RNA helicase, NSP13 binds to RNA-dependent RNA polymerase and acts in concert with the replication-transcription complex to stimulate backtracking and further activate NSP13 helicase activity. These factors make NSP13 a good target for developing new antiviral drugs. In addition, the identification of epitopes within the NSP13 sequence can help design more effective SARS-CoV-2 vaccines.Models have predicted epitopes exhibiting antigenicity, stability and interactions with MHC class-I and class-II molecules. NSP13 (476-490) is an epitope candidate with various predicted HLA restrictions. This epitope can be used to better vaccine design for more durable CD4+ and CD8+ T cell responses for long-lasting immunity.Peso molecular:1,658.9 g/molH-HEIPVLP^NR-OH
Peptide H-HEIPVLP^NR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.CMVpp65 - 20 (VQHTYFTGSEVENVS)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,696.8 g/molH-VYKSPVVSGDTSPRHL-NH2
Peptide H-VYKSPVVSGDTSPRHL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
SARS-CoV 3C-like protease (3CLpro) substrate (C-terminal KK-acid)
3CLpro are the key enzymes required by coronaviruses to replicate. They cleave polyproteins to form replicase. This makes 3CLpro a drug target for protease inhibitors with particular interest to COVID-19. For, example Paxlovid®- has been brought to market as a 3CLpro inhibitor that can be administered orally to reduce coronavirus disease 19 (COVID-19) hospitalisation. Aiming to expand on such advances, synthesis of more substrates for 3CLpro are being generated and tested for their ability to inhibit the protease activity and thus replication cycle of coronaviruses. This product is the natural substrate for 3CLpro, this makes it a useful tool as a control but also for structural manipulation to design inhibitors.
Fmoc-Pro-Rink-Amide MBHA Resin
Fmoc-Pro-Rink-Amide MBHA Resin is an amino acid resin that is used for the synthesis of peptides and proteins. It has a high purity and can be used as a research tool in the fields of pharmacology, protein interactions, receptor binding, ion channels, ligand binding, antibody production, or cell biology. Fmoc-Pro-Rink-Amide MBHA Resin is also an inhibitor of cyclic nucleotide phosphodiesterases. The chemical name for this product is 4-(2(2-(2-(3-(4-(dimethylamino)phenyl)amido)-6(1H)-pyridinyl)ethoxy)ethoxy)benzoic acid methyl ester hydrochloride.
Pureza:Min. 95%HyNic-GLFHAIAHFIHGGWHGLIHGWYG-OH
Peptide HyNic-GLFHAIAHFIHGGWHGLIHGWYG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-LLIYY^TSR^-OH
Peptide H-LLIYY^TSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-GDLGIEIPAEK^-OH
Peptide H-GDLGIEIPAEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Biot-NPSSLFRYLPSD-OH
Peptide Biot-NPSSLFRYLPSD-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Ac-CKHWRSVYDEFGEL-OH
Peptide Ac-CKHWRSVYDEFGEL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-S^LS^LSPGK^-OH
Peptide H-S^LS^LSPGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Angiotensin I (1-9)
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C56H78N16O13Peso molecular:1,183.35 g/molAc-RRCPLYISYDPVCRR-NH2
Peptide Ac-RRCPLYISYDPVCRR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-GLDSEESYPYEAK^^-OH
Peptide H-GLDSEESYPYEAK^^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Azide-IELLQARC-OH
Peptide Azide-IELLQARC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-TGGKAPR-NH2
Peptide Ac-TGGKAPR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Neuregulin 4 (Nrg4) / pro-Neuregulin 4 (1-61) (Human)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:6,656.63 g/molAc-WEDWVGWI-NH2
Peptide Ac-WEDWVGWI-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-GEGGPQGPR^-OH
Peptide H-GEGGPQGPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Myr-KFEEERARAKWDT-OH
Peptide Myr-KFEEERARAKWDT-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Leuprolide Acetate
Leuprolide acetate is a synthetic peptide analogue of naturally occurring gonadotropin releasing hormone (GnRH also known as luteinising hormone-releasing hormone, LHRH). Leuprolide Acetate has a longer half-life and a higher affinity to the pituitary GnRH-receptor than physiological GnRH due to the presence of a D-amino acid. Leuprolide acts as a super-agonist of the pituitary gonadotropin-releasing hormone (GnRH) receptor in the hypothalamo-pituitary-gonadal axis and disrupts the maintenance of the normal hypothalamo-pituitary-gonadal axis and desensitizes the GnRH receptor. This results in lower levels of testosterone in the blood. Leuprolide is used to treat prostate cancer, endometriosis, fibroids and precocious puberty. Peptide is for research purposes only, strictly not for human use.Peso molecular:1,208.6 g/molInsulin 15-24 (HLA-A*02:01)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
H-ILSP^FLPLL^-OH
Peptide H-ILSP^FLPLL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Neurogranin (43-75) (Human, Monkey)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:2,984.34 g/molH-SLVMSGPYELK^-OH
Peptide H-SLVMSGPYELK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-FQPTLLTLPR^-OH
Peptide H-FQPTLLTLPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-DVINEAWFPEDQR^-OH
Peptide H-DVINEAWFPEDQR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.LCBiot-TFCGTPEYLAPEVLEDNDYGR-OH
Peptide LCBiot-TFCGTPEYLAPEVLEDNDYGR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-PRCGVPDLGR-NH2
Peptide Ac-PRCGVPDLGR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-RLFFYRKSV^-OH
Peptide H-RLFFYRKSV^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Indolicidin
Indolicidin is a natural cationic cathelicidin family anti-microbial peptide (AMP) with a very wide killing spectrum which includes: Gram-positive and Gram-negative bacteria, fungi, protozoa and HIV. It is also an immune system modulator and an inhibitor of aminoglycoside antibiotic-resistance enzymes.Indolicidin contains 5 tryptophan residues (39% of peptide content)- the highest tryptophan proportion ever seen in a peptide or protein.When indolicidin interacts with biological membranes it assumes a wedge- shaped conformation, with the hydrophobic tryptophan residues in the trough of the wedge, and positively charged regions flanking them at each end. If fully extended, indolicidin is able to span both lipid bilayers despite only consisting of 13 amino acid residues. This is possible because indolicidin adopts an approximate poly-l-proline type II helix conformation, which is characterized by very high helical pitches.The exact mode of action of indolicidin is still unknown. At bactericidal concentrations the peptide appears to translocate through the membrane into the cytosol where it may bind to nucleic acids, whereas at higher concentrations it is membranolytic.
Cor e Forma:PowderPeso molecular:1,906.28 g/molRKOpep
Peptide identified through phage display that binds to colorectal cancer cell line RKO cells, as well as other cancer cells including Caco-2, HCT 116 and HCT-15, but not to normal cells, possibly through targeting the monocarboxylate transporter 1, which has been implicated in colorectal cancer progression and prognosis.
Peso molecular:920.4 g/molH-EV^DPIGHLY-OH
Peptide H-EV^DPIGHLY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-QLQPFPQPELPY-OH
Peptide H-QLQPFPQPELPY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
(Gln²²,Asn²³)-Amyloid β-Protein (1-40)
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Fórmula:C194H297N55O56SPeso molecular:4,327.9 g/molH-VLNDINQAK^-OH
Peptide H-VLNDINQAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
