Peptídeos

Adjuvant Peptide is a glycol ether that has been shown to have biological properties. It is used in the production of Immunoassays and other biochemicals. Adjuvant Peptide is an experimental model for immunity, as it stimulates cellular responses and alters the immune system's response to antigens. It shows potential for use in treating bowel diseases, such as ulcerative colitis, because of its ability to stimulate macrophage activity and induce cytokine production.

Physalaemin is a peptide that has been found to be an activator of the G-protein coupled receptor. Physalaemin has been shown to inhibit ion channels, such as potassium channels and calcium channels. Physalaemin may also inhibit the activity of certain ligands, such as bradykinin and substance P. This peptide can also act as a research tool for pharmacology and cell biology.

Cbz-N-Amido-dPEG®12-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Cbz-N-Amido-dPEG®12-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

[Met(O)12]-ANP (Human, 1-28) is a peptide that activates the guanylate cyclase. It has been shown to bind to the receptor for ANP, which is present in many cell types. The binding of [Met(O)12]-ANP (Human, 1-28) to its receptor leads to an increase in intracellular cGMP levels and consequently an increase in intracellular cAMP levels. This product is a research tool for protein interactions and can be used as an inhibitor or activator. The purity of this product is >98%.

BNP-32 is a peptide that is an activator of the B2 receptor. It has been shown to inhibit the ion channels in cells, which may be due to its binding to the ligand-binding site on the receptor. BNP-32 has also been shown to bind to antibodies and can be used as a research tool for cell biology or other areas of life science. BNP-32 is a high purity product with CAS No. 123337-89-3.

E-64-c is a research tool that is used to activate the receptor of a cell. This ligand can bind to the receptor and form a complex, which will then be able to interact with other proteins in the cell. This process can lead to changes in ion channel activity, protein synthesis, or gene expression. E-64-c has been shown to inhibit the activity of ion channels such as calcium channels and potassium channels, as well as protein synthesis. It also binds to antibodies and blocks their binding sites on cells.br>
E-64-c is a high purity ligand that can be used for studying protein interactions or pharmacological purposes. The potency of this ligand has been tested by measuring its ability to inhibit the binding of various peptides such as vasopressin and angiotensin II.

Bz-Gly-Gly-Gly is a prodrug that is metabolized by enzymatic hydrolysis to its active form, hippurylglycylglycine. The prodrug has been shown to have minimal toxicity in mice and humans, and it binds to the target enzyme of infectious diseases (e.g., HIV) with high affinity. Bz-Gly-Gly-Gly has been shown to be effective in vitro against human immunodeficiency virus type 1 (HIV1) and mouse tumor models, as well as in vivo against mouse leukemia cells. The drug has also been shown to be safe at physiological levels in mice.

m-dPEG®2-NHS Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®2-NHS Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Gla17,21,24-Osteocalcin is a peptide that belongs to the family of proteins that have bone-building properties. Osteocalcin is produced by osteoblasts and its production increases in response to activation by parathyroid hormone. It is also an activator of ion channels and has been found to be involved in regulating calcium homeostasis. Gla17,21,24-Osteocalcin has been shown to inhibit protein interactions with the receptor and ligand. This peptide also binds to receptor sites on cells and inhibits the activity of G protein-coupled receptors (GPCRs).

Bis-dPEG®17-PFP Ester is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®17-PFP Ester is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.

Bz-Ala-OMe is a reactive mercuric chloride that undergoes hydrolysis to form reactive mercuric acetate. It has been shown that the activation energy of the reaction is high and the reaction can be initiated by soybean trypsin. The reactive site of Bz-Ala-OMe is composed of chloride atoms and sephadex g-100. This compound reacts with serine proteases, such as trypsin or chymotrypsin, to form an amide intermediate. This intermediate reacts with n-acetyl-l-tyrosine to produce a chloromethyl ketone which then undergoes a nucleophilic attack by histidine to produce histamine in the presence of H2O2 or O2. Histamine binds to H1 receptors in the body, leading to an inflammatory response.

ANP (Rat, 3-28) is a peptide that is a potent inhibitor of protein interactions. This peptide binds to the ligand-binding domain of the receptor and blocks the binding of the ligand. ANP (Rat, 3-28) also has high purity and can be used as a research tool or an antibody in life science studies.

Hydroxy-dPEG®8-t-Butyl Ester is a PEG polymer categorised as monofunctional (OH-PEG-X). Used as a linker, hydroxy-dPEG®8-t-Butyl Ester is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.