Peptídeos

Neuromedin U Precursor-Related Peptide 33 (Rat, Mouse) is a research tool that can be used to study the effects of neuromedin U on the activation of receptors. This peptide is a ligand for the receptor and has been shown to inhibit ion channels. Neuromedin U Precursor-Related Peptide 33 (Rat, Mouse) may also be used as an antibody or in protein interactions studies. This product is made from high purity materials and can be used in pharmacology and life science experiments.

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Leptin is a hormone that regulates energy metabolism by modulating appetite and body weight. Leptin is produced by fat cells and signals to the hypothalamus of the brain about how much fat tissue there is. It also helps regulate other metabolic processes, such as insulin resistance and glucose tolerance. Leptin has been shown to have an anorectic effect in rodents, which may be due to its ability to reduce food intake or increase energy expenditure. In humans, leptin levels are higher in obese individuals than in those with normal weight, which indicates that this hormone may play a role in obesity.

LISA-101 is a peptide that can be used as a research tool for the study of receptor activation and ligand binding. LISA-101 is an inhibitor of ion channels, which are proteins that allow electrically charged particles to move in and out of cells. LISA-101 binds to receptors on the surface of cells and blocks ion channels from opening. This prevents the flow of ions across the membrane, which blocks nerve impulses, leading to a decrease in pain sensation. LISA-101 has been shown to inhibit voltage-gated sodium channels and calcium channels, both which are involved in pain perception.

Anti Bombesin Serum is a research tool that can be used to study the interactions of proteins with receptors and ion channels. Anti Bombesin Serum may also be used to study the inhibition of peptide receptor activity, for example, by bombesin or other ligands. This product is made from high-quality antibodies that have been selected for their ability to bind bombesin.

Insl3 is a protein that is localized in the ovary and human chorionic gonadotropin. It is also found in human serum. In animals, Insl3 causes fertility. In humans, it stimulates the development of the gubernaculum, which attaches to the testes. The expression of Insl3 increases during puberty and continues to be expressed throughout adulthood. Insl3 is translated from mRNA as a precursor protein with an N-terminal signal peptide sequence that directs its secretion from the cell into the extracellular space. The Insl3 precursor protein has two C-terminal domains: an internal domain and a carboxy-terminal domain. These domains are translated from separate initiation codons on one mRNA molecule. The internal domain contains sequences for translation initiation, ribosome binding sites, and translational stop codons; these sequences are not present in the carboxy-terminal domain. Insl3 can be detected by using an

Bromoacetamido-dPEG®24-Amido-DBCO is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromoacetamido-dPEG®24-Amido-DBCO is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

NPY is a peptide that is released by neurons and acts as an activator. It is also found in the central nervous system and regulates appetite, as well as other autonomic, behavioral, and endocrine functions. NPY has been shown to be an inhibitor of ion channels in the central nervous system. NPY has been shown to bind to receptors on the surface of cells, which are ligands for NPY. This binding activates or inhibits the receptor's signaling pathway. The CAS number for NPY is 1139-14-1 and it has a molecular weight of 9.6 kDa.END>

Anti-TNF-alpha (rat) serum is a protein that blocks the effects of tumor necrosis factor-alpha. This protein has been shown to regulate the immune system and inhibit inflammation. Anti-TNF-alpha (rat) serum is a high quality, purified protein for use as a research tool in cell biology or other life science applications. The product is supplied at a concentration of 1 mg/ml in phosphate buffered saline with 0.02% sodium azide and is suitable for use in mammalian experiments.

FRETS-25Lys is a peptide that can be used as an activator, inhibitor, or ligand for various receptors and ion channels. It has been shown to bind with high affinity to the acetylcholine receptor on the surface of muscle cells. FRETS-25Lys also inhibits the interaction between protein kinase C (PKC) and phospholipase Cγ2 (PLCγ2).

β-Defensin-1 is a member of the α-defensin family of antimicrobial peptides. It has been shown to be an activator of the LPS receptor and is involved in the regulation of ion channels in cells. β-Defensin-1 is a ligand for the GPR37 receptor and inhibits protein synthesis, which may be due to its ability to bind to other proteins, such as chemokines. β-Defensin-1 also has antibacterial activity against some strains of bacteria, including Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus.
β-Defensin-1 is a high purity recombinant human protein that can be used as an inhibitor for pharmacological studies.

Cellulose synthase is a crucial enzyme involved in the synthesis of cellulose. Cellulose is an aggregation of unbranched polymer chains made of β-(1-4)-linked glucose residues, and is a component of primary and secondary cell walls - functioning to primarily maintain strength and shape in cells.Cellulose is synthesised by large cellulose synthase complexes (CSCs), which consist of synthase protein isoforms (CesA) that are arranged into a unique hexagonal structure.Specifically the isoform cellulose synthase 7 takes part in secondary cell wall cellulose synthesis.

The coronavirus (CoV) nucleoprotein is the major component of CoV structural proteins. The nucleoprotein has a critical role in virus assembly and RNA transcription. The nucleoprotein is essential in the formation of helical ribonucleoproteins and in regulating viral RNA synthesis. The nucleoprotein can also regulate infected host cellular mechanisms. It is highly expressed during infection and may induce protective immune responses against SARS-CoV and SARS-CoV-2.The nucleoprotein residues HIDAYKTFPPTEPKK (356-370) from SARS-CoV-2 have been identified as a T-cell epitope with a predicted HLA restriction. Immune targeting of confirmed epitopes may potentially offer protection against SARS-CoV-2 and help the development of vaccines for long-lasting immunity.

The cyclic AMP (cAMP) response element binding protein (CREB) is a transcription factor that regulates the transcription of several genes that mediate important cellular processes. CREB is phosphorylated by several kinases, including PKA- Akt- and CamK I, II, and IV. Phosphorylated pCREB translocates to the nucleus, where it forms homodimers or heterodimers, and recruits p300/CREB binding protein (CBP) to initiate transcription of its target genes. pCREB is an important regulator of apoptosis and is also involved in modulating several immune processes and neuronal plasticity. CREB signalling has a critical role in the formation of memories and may be dysfunctional in the brains of Alzheimer's disease (AD).Peptide is labelled with an N-terminal 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.

This is a Biologically Active Peptides, Short=PN-II, Proteomics, Amyloid Precursor Protein, New England Peptide calibrated to 25nmol. This peptide has been shown to be a major component of amyloid plaques in Alzheimer's Disease. It is one of the most abundant proteins in the brain and is found in association with beta-amyloid protein (A4). The precursor protein for APP is encoded by the gene on chromosome 21. APP and its products are involved in many cellular processes such as signal transduction, cell proliferation, apoptosis and inflammation. APP can be cleaved by Beta-secretase or Gamma secretase to release A4 and N-APP.

D-Amino Acid Oxidase is an enzyme that catalyzes the conversion of D-amino acid to alpha keto acid and ammonia. It is also known as DAAO or DAO.

monoFITC INSL5 is a peptide that can be used as a research tool to investigate the interactions between proteins and ligands. It is an activator of the Insulin-like growth factor 1 receptor (IGF1R). This peptide has been shown to inhibit IGF1R-mediated signaling pathways that lead to cell proliferation.