Moduladores enzimáticos
Moduladores de enzimas são compostos que podem aumentar ou inibir a atividade de enzimas, regulando assim a taxa de reações bioquímicas. Esses moduladores desempenham um papel crucial no controle de vias metabólicas, sinalização celular e vários processos fisiológicos. Os moduladores de enzimas são amplamente utilizados em pesquisa e desenvolvimento de medicamentos para estudar as funções enzimáticas e desenvolver agentes terapêuticos. Na CymitQuimica, oferecemos uma ampla gama de moduladores de enzimas de alta qualidade para apoiar sua pesquisa em regulação enzimática e descoberta de medicamentos.
Subcategorias de "Moduladores enzimáticos"
Foram encontrados 693 produtos de "Moduladores enzimáticos"
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Larotrectinib sulphate
CAS:A potent ATP-competitive inhibitor of tropomyosin-related kinases (TRK1, TRK2 and TRK3), members of the receptor tyrosine kinase family of neurotrophin receptors. Tumors with oncogenic TRK fusions are sensitive to larotrectinib, leading to reduced proliferation and tumor growth in patients with soft tissue sarcoma, triple-negative breast cancer and lung cancer.Fórmula:C21H22F2N6O2H2SO4Pureza:Min. 95%Peso molecular:526.51 g/molTacrolimus
CAS:Antirheumatic; immunosuppressant; neuroprotective; neuroregenerativeFórmula:C44H69NO12Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:804.02 g/molGNE 6776
CAS:Specific inhibitor of the ubiquitin specific protease-7 (USP7), which is a validated deubiquitinase of the E3 ubiquitin-protein ligase MDM2. The compound inhibits the USP7 deubiquitinase activity by binding to acidic amino acid residues important for the interaction with ubiquitin. Induces tumor cell death and enhances cytotoxicity of chemotherapeutic agents.Fórmula:C20H20N4O2Pureza:Min. 95%Peso molecular:348.4 g/mol5-Fluorouracil - Bio-X ™
CAS:5-Fluorouracil is a cytotoxic drug that inhibits the synthesis of DNA. It is used in combination therapy to treat cancer and is a pyrimidine analog. This drug inhibits the formation of thymidylate synthase from uracil. As a result, this leads to DNA and RNA synthesis inhibition and cell death.Fórmula:C4H3FN2O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:130.08 g/molGRL 0617
CAS:A novel non-covalent inhibitor of the PLpro protease from SARS-CoV-2 and SARS-CoV viruses. GRL 0617 inhibits the proteolytic processing of the viral polypeptide. As PLpro also acts as a protease in pathways involved in innate immunity, there are indications that it can promote immunity against the virus.Fórmula:C20H20N2OPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:304.39 g/molOdiparcil
CAS:Dipeptidyl peptidase 4 (DPP4) inhibitor
Fórmula:C15H16O6SPureza:Min. 99%Cor e Forma:PowderPeso molecular:324.35 g/molIdelalisib
CAS:Idelalisib is a pharmaceutical drug that functions as a PI3Kδ inhibitor, developed through synthetic chemical processes. Its mode of action involves selectively targeting and inhibiting phosphatidylinositol 3-kinase delta (PI3Kδ), a lipid kinase that plays a crucial role in the signaling pathways responsible for cell proliferation, survival, and differentiation. By inhibiting this enzyme, Idelalisib effectively impedes pathways that are often hyperactivated in certain hematologic malignancies, thereby exerting antitumor effects.Fórmula:C22H18FN7OPureza:Min. 95%Cor e Forma:PowderPeso molecular:415.42 g/molTemsirolimus
CAS:mTOR serine/threonine kinase inhibitorFórmula:C56H87NO16Pureza:Min. 95%Cor e Forma:PowderPeso molecular:1,030.29 g/molBKM 120
CAS:Inhibitor of pan-class I PI3K family of lipid kinases; antineoplastic
Fórmula:C18H21O2N6F3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:410.39 g/molN-Butyldeoxynojirimycin
CAS:Competitive inhibitor of ceramide-glycosyltransferase used for substrate reduction therapy in lysosomal storage disorders. It inhibits glucosylceramide synthase, which catalyses the initial step in glycosphingolipid biosynthetic pathway. This compound delays the onset of symptoms in type 1 Gaucher disease, Sandhoff disease and Tay-Sachs disease. It also reduces brain abnormalities in mucolipidosis type IV.Fórmula:C10H21NO4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:219.28 g/molPKC 412
CAS:Inhibits multiple protein kinases, such as PKC and FLT3Fórmula:C35H30N4O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:570.64 g/molTivozanib
CAS:Inhibitor of VEGF receptorsFórmula:C22H19ClN4O5Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:454.86 g/molPimasertib
CAS:A selective inhibitor of MEK1/2 kinase. Anti-proliferative and pro-apoptotic in multiple myeloma (MM) cells via G0/G1 cell cycle arrest and caspase 3 and PARP cleavage, respectively. Synergistic with other anti-MM therapies. Has anti-tumor effects in some solid tumors, such as in K-ras mutated colorectal cancer.Fórmula:C15H15FIN3O3Pureza:Min. 95%Cor e Forma:White To Yellow SolidPeso molecular:431.2 g/molDabigatran etexilate - Bio-X ™
CAS:Dabigatran is an anticoagulant that is used for the treatment of atrial fibrillation and prevention of venous thromboembolic events. It is a drug that acts as an inhibitor of the enzyme thrombin. Dabigatran inhibits platelet activation and aggregation, which reduces the risk of stroke or other vascular events. Dabigatran is a prodrug and does not have any activity in its active form.
Fórmula:C34H41N7O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:627.73 g/molTacrolimus monohydrate
CAS:Anti-rheumatic; immunosuppressant; neuroprotective; neuroregenerativeFórmula:C44H69NO12·H2OPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:822.03 g/molJNJ 10198409
CAS:Selective inhibitor of the platelet derived growth factor receptor PDGFRβ with IC50 value of 4.2 nM. JNJ 10198409 inhibits the PDGFRβ kinase activity and its downstream signalling leading to anti-proliferative and anti-angiogenic effects, which were confirmed in various tumoral cell lines.Fórmula:C18H16FN3O2Pureza:Min. 95%Cor e Forma:SolidPeso molecular:325.34 g/molApatinib mesylate
CAS:Inhibitor of VEGFR; antineoplasticFórmula:C24H23N5O·CH4O3SPureza:Min. 95%Peso molecular:493.58 g/molA 939572
CAS:Inhibitor of stearoyl-CoA desaturase SCD1 with IC50 of 6.3 nM, as measured in the SCD1-expressing human microsomes. A 939572 exhibited anticancer activity as it reduced cell proliferation and triggered cell killing in human non-small cell lung carcinoma cells. A 939572 inhibited tumour growth in an in vivo model for gastric carcinoma and reduced the oleic acid:stearic acid ratio in mouse liver and plasma.Fórmula:C20H22ClN3O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:387.86 g/molKU-0063794
CAS:Inhibits mTORC1 and mTORC2 serine/threonine kinasesFórmula:C25H31N5O4Pureza:Min. 95%Cor e Forma:White To Beige To Yellow SolidPeso molecular:465.54 g/molNiacinamide
CAS:Vitamin B3; antioxidant; favours cell repairFórmula:C6H6N2OPureza:98.5 To 101.5 Area-%Cor e Forma:White PowderPeso molecular:122.12 g/mol
