H-His-Cys-Lys-Phe-Trp-Trp-OH

CAS: 172546-75-7

Ref. 01-4026848

Informação sobre produto

• Nome: H-His-Cys-Lys-Phe-Trp-Trp-OH

Descrição

HCKFWW, potent inhibitor of the HIV-encoded integrase (IN), the enzyme responsible for the integration of HIV DNA into the human genome. HCKFWW inhibits IN-mediated 3'processing and integration with an IC50 of 2 uM. The peptide is also active on IN proteins from other retroviruses such as HIV-2, feline immunodeficiency virus and Moloney murine leukemia virus. It was also found to inhibit the disintegration reaction, suggesting that this hexapeptide acts at or near the catalytic site of IN.

• Marca: Bachem

Propriedades químicas

• Peso molecular: 906.08
• Fórmula: C₄₆H₅₅N₁₁O₇S
• Pureza: 97.9%
• Cor/forma: White Lyophilisate