Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH₂

CAS: 158584-08-8

Ref. 01-4030841

Informação sobre produto

• Nome: Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH₂
• Sinónimos: NFF-2, Nff 2, (7-Methoxycoumarin-4-yl)acetyl-arginyl-prolyl-lysyl-prolyl-tyrosyl-alanyl-norvalyl-tryptophyl-methionyl-(2,4-dinitrophenyl)lysinamide, Mca-arg-pro-lys-pro-tyr-ala-nva-trp-met-lys(dnp)-NH2, N2-((7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl)-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-tyrosyl-L-alanyl-L-norvalyl-L-tryptophyl-L-methionyl-N6-(2,4-dinitrophenyl)-L-lysinamide, L-Lysinamide, N2-((7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl)-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-tyrosyl-L-alanyl-L-norvalyl-L-tryptophyl-L-methionyl-N6-(2,4-dinitrophenyl)-
• CAS: 158584-08-8

Descrição

The FRET substrate Mca-RPKPYA-Nva-WMK(Dnp)-amide was hydrolyzed 60 times more rapidly by stromelysin 1 (MMP-3) (kcat/Km= 59400 M-1s-1) than by interstitial collagenase (MMP-1). However, it showed little discrimination between MMP-3, gelatinase A (MMP-2) (kcat/Km= 54000 M-1s-1), and gelatinase B (MMP-9) (kcat/Km= 55300 M-1s-1). Metalloelastase (MMP-12) digested this fluorogenic substrate with a kcat/Km of 243000 M-1s-1.

• Marca: Bachem

Propriedades químicas

• Peso molecular: 1656.89
• Fórmula: C₇₉H₁₀₅N₁₉O₁₉S
• Pureza: > 95%
• Cor/forma: White Whitish Powder