Terlipressin

CAS: 14636-12-5

Ref. 01-4061053

Informação sobre produto

• Nome: Terlipressin
• Sinónimos: N-(N-(N-Glycylglycyl)Glycyl)-8-L-Lysinevasopressin, (2S)-1-[(4S,7S,10S,13S,16S,19S)-19-[[2-[[2-[(2-Aminoacetyl)Amino]Acetyl]Amino]Acetyl]Amino]-13-Benzyl-10-(2-Carbamoylethyl)-7-(Carbamoylmethyl)-16-[(4-Hydroxyphenyl)Methyl]-6,9,12,15,18-Pentaoxo-1,2-Dithia-5,8,11,14,17-Pentazacycloicosane-4-Carbonyl]-N-[(1S)-5-Amino-1-(Carbamoylmethylcarbamoyl)Pentyl]Pyrrolidine-2-Carboxamide, (2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl}pyrrolidine-2-carboxamide (non-preferred name), Terlipressin Acetate, [N-α-Triglycyl-8-lysine]-vasopressin, 1-Triglycyl-8-lysine vasopressin, Glycylpressin, Glypressin, Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin, Nα-Glycyl-glycyl-glycyl-lysine-vasopressin, Nα-Glycylglycylglycyl-vasopressin, Nα-Gly-Gly-Gly-8-Lys-vasopressin, Remestyp, Terlipressina, Terlipressine, Triglycyl-8-lysine-vasopressin, Vasopressin, N-(glycylglycylglycyl)-8-L-lysine-, Vasopressin, N-[N-(N-glycylglycyl)glycyl]-8-L-lysine-

Descrição

Terlipressin is a synthetic analog of vasopressin which is used as a vasoactive drug in the management of hypotension. It acts as a prodrug, as it is converted to (Lys⁸)-vasopressin by removal of the N-terminal triglycine in vivo. This vasopressin analog has a longer duration of action and a better safety profile than the parent compound. Terlipressin has found application in the management of acute variceal hemorrhage (esophageal varices), hepatorenal syndrome, and norepinephrine-resistant septic shock.

• Marca: Bachem

Propriedades químicas

• Peso molecular: 1227.39
• Fórmula: C₅₂H₇₄N₁₆O₁₅S₂
• Pureza: ≥ 98%
• Cor/forma: White