11-Dehydrocorticosterone-13C3

CAS: 72-23-1

Ref. 3D-AAA07223

Informação sobre produto

• Nome: 11-Dehydrocorticosterone-13C3
• Sinónimos: 11-Dehydrocorticosteron, 11-Dehydrocorticosterone, 11-Oxo-11-deoxycorticosterone, 11-Oxocorticosterone, 17-(1-keto-2-Hydroxyethyl)-Δ⁴-androsten-3,11-dione, 21-Hydroxypregn-4-Ene-3,11,20-Trione, 4-Pregnen-21-ol-3,11,20-trione, Corticosterone, 11-dehydro-, Dehydrocorticosterone, Kendall's compound A, Nsc-9702, Pregn-4-ene-3,11,20-trione, 21-hydroxy-, Δ⁴-Pregnen-21-ol-3,11,20-trione, Δ⁴-Pregnene-21-ol-3,11,20-trione

Descrição

11-Dehydrocorticosterone-13C3 is a synthetic glucocorticoid that is used as a nasal drug. It has been shown to inhibit the production of inflammatory cytokines, such as tumor necrosis factor and interleukin-1β, which are involved in the pathogenesis of autoimmune diseases. 11-Dehydrocorticosterone-13C3 binds to the glucocorticoid receptor with high affinity and specificity and possesses a hydroxyl group at C3 position. It is effective in inhibiting the production of proinflammatory cytokines in 3T3-L1 preadipocytes by blocking the function of nuclear factor kappa B (NFκB). It also inhibits the release of colony stimulating factors, such as granulocyte macrophage colony stimulating factor (GMCSF) and granulocyte colony stimulating factor (GCSF), from 3t3-l1 preadipocytes.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 347.42 g/mol
• Fórmula: C₂₁H₂₈O₄
• Pureza: Min. 95%