Suramin

CAS: 145-63-1

Ref. 3D-AAA14563

Informação sobre produto

• Nome: Suramin
• Sinónimos: Farma 939, 1,3,5-Naphthalenetrisulfonic acid, 8,8′-[ureylenebis[m-phenylenecarbonylimino(4-methyl-m-phenylene)carbonylimino]]di-, Farma, 8,8′-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis[1,3,5-naphthalenetrisulfonic acid], 1,3,5-Naphthalenetrisulfonic acid, 8,8′-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-

Descrição

Suramin is a nonsteroidal anti-inflammatory drug that binds to the ryanodine receptor, which is an intracellular calcium channel. It prevents the release of calcium from the sarcoplasmic reticulum, leading to decreased production of reactive oxygen species and preventing cell death. Suramin has been shown to inhibit the growth of murine sarcoma virus in cells by inhibiting the synthesis of a protein called growth factor-β1 (GF-β1). This drug also inhibits glycol ethers, which are known carcinogens that can cause DNA damage in cancerous cells. Suramin has been shown to have an apoptosis pathway, which is a biological process by which cells self-destruct when they are no longer needed or have become damaged. The binding of suramin to polymerase chain reaction (PCR) can be used as a diagnostic tool for detecting cancer tissues. Suramin has also been shown to bind to dextran sulfate and natural compounds with similar

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 1,297.3 g/mol
• Fórmula: C₅₁H₄₀N₆O₂₃S₆
• Pureza: Min. 95%