Ethylmalonic Acid

CAS: 601-75-2

Ref. 3D-AAA60175

Informação sobre produto

• Nome: Ethylmalonic Acid
• Sinónimos: 1,1-Propanedicarboxylic acid, 2-Ethylmalonic acid, 2-Ethylpropanedioic acid, Ethylpropanedioate, Ethylpropanedioic Acid, Malonic acid, ethyl-, Malonic acid, ethyl- (8CI), Nsc 96615, Propanedioic acid, 2-ethyl-, Propanedioic acid, ethyl-, Propanedioic acid, ethyl- (9CI), alpha-Carboxybutyric acid, α-Carboxybutyric acid
• CAS: 601-75-2

Descrição

Ethylmalonic acid (EA) is a metabolic intermediate that is synthesized in the mitochondria. It is a product of the oxidation of malonyl-CoA and succinyl-CoA by the enzyme dehydrogenase. EA has been shown to be produced in vivo, and can be used as a marker for mitochondrial dysfunction. EA levels are increased in patients with metabolic disorders such as diabetes mellitus and obesity, as well as other diseases such as cancer, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, multiple sclerosis, amyotrophic lateral sclerosis (ALS), heart failure, chronic obstructive pulmonary disorder (COPD), kidney diseases, liver diseases and anemia. EA levels can also be used to diagnose mitochondrial disorders such as mitochondrial DNA depletion syndrome and Kearns-Sayre syndrome.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 132.11 g/mol
• Fórmula: C₅H₈O₄
• Pureza: Min. 95%