Informação sobre produto
- 1-Chloro-2-Iodobenzene
- 1-Iodo-2-chlorobenzene
- 2-Chloro-1-iodobenzene
- 2-Chloroiodobenzene
- 2-Chlorophenyl iodide
- 2-Iodochlorobenzene
- 2-Iodophenyl chloride
- Benzene, 1-chloro-2-iodo-
- NSC 32860
- O-Iodochlorobenzene
- Ver mais sinónimos
- o-Chloroiodobenzene
- o-Chlorophenyl iodide
1-Chloro-2-iodobenzene is a chemical that is used in the synthesis of drugs and other organic compounds. It has been shown to be an effective inhibitor of HIV infection, as well as a potent inhibitor of genotoxic activity. 1-Chloro-2-iodobenzene cleaves to form two products: a palladium complex and a copper complex. The reaction products are then subjected to nucleophilic attack by the enzyme human immunodeficiency virus type 1 reverse transcriptase, which results in the formation of an intermediate product with increased stability. This final product inhibits the replication of HIV by binding to the viral DNA polymerase and preventing RNA synthesis. Chemical ionization is used for mass spectrometry analysis, which can identify the peaks corresponding to these products.
Propriedades químicas
Consulta técnica sobre: 3D-AAA61541 1-Chloro-2-iodobenzene
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