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rac-(4aR,9bS)-2,8-Dimethyl-1H,2H,3H,4H,4aH,5H,9bh-pyrido[4,3-b]indole
CAS: 75494-88-1
Ref. 3D-ADA49488
50mg | 325,00 € | ||
500mg | 1.216,00 € |
Informação sobre produto
Dimebon is a drug that binds to dopamine receptors (D2 and D3) and inhibits locomotor activity in rats. It also has been found to be effective in the treatment of cancer-induced cachexia, as well as bowel disease. Dimebon is a hydrogenated form of rac-(4aR,9bS)-2,8-dimethyl-1H,2H,3H,4H,4aH,5H,9bh-pyrido[4,3-b]indole. The drug was originally synthesized in the Soviet Union for use as an antidepressant but was never marketed because it caused severe side effects such as tardive dyskinesia. Dimebon has been shown to cause neuronal death through inhibition of the growth factor BDNF and its receptor activity. It also blocks dopamine release from nerve cells in the striatum. Dimebon is water soluble and can be taken orally or injected intravenously.
Propriedades químicas
Consulta técnica sobre: 3D-ADA49488 rac-(4aR,9bS)-2,8-Dimethyl-1H,2H,3H,4H,4aH,5H,9bh-pyrido[4,3-b]indole
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