Informação sobre produto
2-Iodo-1-methyl-1H-indole is a halogenated indole that has been used for the synthesis of 2,4,6-trisubstituted pyridines. It can be prepared by the reaction of iodomethane with aniline in acetonitrile. The addition of a base such as potassium carbonate to the reaction mixture leads to the formation of an unsymmetrical dimer. In order to avoid this undesired product, it is necessary to react with excess iodide ion and use a more nucleophilic catalyst such as palladium on activated copper powder or copper(I) chloride. The coupling reactions are best performed in nitric acid solution at room temperature using copper(II) nitrite as oxidant and a base such as sodium nitrite.
2-Iodo-1-methyl-1H-indole is a halogenated indole that has been used for the synthesis of
Propriedades químicas
Consulta técnica sobre: 3D-ADA83363 2-Iodo-1-methyl-1H-indole
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