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N1-[2-Bromo-4-(trifluoromethyl)phenyl]acetamide
CAS: 175135-49-6
Ref. 3D-AHA13549
250mg | 303,00 € | ||
2500mg | 1.151,00 € |
Informação sobre produto
- 2'-Bromo-4'-(trifluoromethyl)acetanilide
- 4-Acetamido-3-bromobenzotrifluoride
- Acetamide, N-[2-bromo-4-(trifluoromethyl)phenyl]-
- N-[2-bromo-4-(trifluoromethyl)phenyl]acetamide
N1-[2-Bromo-4-(trifluoromethyl)phenyl]acetamide (NAPA) is a drug metabolite that is formed by cytochrome P450 enzymes in the liver. This metabolite has been detected in human plasma, urine and faeces. NAPA has been shown to be a major metabolite of the antidepressant drug nortriptyline. The main route of elimination for NAPA is through conjugation with glucuronic acid. High-performance liquid chromatography can be used for the separation and quantification of metabolites such as NAPA. The use of on-line introduction increases sensitivity and reduces detection time. Chromatographic profiles are often used to distinguish between different compounds with similar properties, such as NAPA and its major metabolites.
Propriedades químicas
Consulta técnica sobre: 3D-AHA13549 N1-[2-Bromo-4-(trifluoromethyl)phenyl]acetamide
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