Mitomycin C - High Purity

CAS: 50-07-7

Ref. 3D-AM161650

Informação sobre produto

• Nome: Mitomycin C - High Purity
• Sinónimos: [(1aS,8S,8aR,8bS)-6-Amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methy
• Marca: Biosynth
• Descrição: Mitomycin C is a cytotoxic agent that inhibits DNA synthesis. This product is tested according to USP specification. Mitomycin C has been shown to be effective against resistant mutants and carcinoma cell lines. It also has genotoxic activity and induces statistically significant chromosome aberrations in mammalian cells. Mitomycin C is toxic to the mitochondria, which may be due to its ability to induce mitochondrial membrane potential collapse, leading to apoptosis. Mitomycin C binds to the response element in the genome, causing transcriptional repression of a number of genes involved in cell proliferation, differentiation, or apoptosis. Mitomycin C inhibits squamous carcinoma cells by binding to their DNA and preventing RNA synthesis.

Propriedades químicas

• Peso molecular: 334.33 g/mol
• Fórmula: C₁₅H₁₈N₄O₅
• Pureza: Cas Rn [50-07-7] M. F. C15H18N4O5
• Cor/forma: Powder